aboutsummaryrefslogtreecommitdiff
path: root/gnu/packages/cran.scm
blob: 19bb4ebd0c89dbadf4359c1b3a3ba639d44952cd (plain)
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
31
32
33
34
35
36
37
38
39
40
41
42
43
44
45
46
47
48
49
50
51
52
53
54
55
56
57
58
59
60
61
62
63
64
65
66
67
68
69
70
71
72
73
74
75
76
77
78
79
80
81
82
83
84
85
86
87
88
89
90
91
92
93
94
95
96
97
98
99
100
101
102
103
104
105
106
107
108
109
110
111
112
113
114
115
116
117
118
119
120
121
122
123
124
125
126
127
128
129
130
131
132
133
134
135
136
137
138
139
140
141
142
143
144
145
146
147
148
149
150
151
152
153
154
155
156
157
158
159
160
161
162
163
164
165
166
167
168
169
170
171
172
173
174
175
176
177
178
179
180
181
182
183
184
185
186
187
188
189
190
191
192
193
194
195
196
197
198
199
200
201
202
203
204
205
206
207
208
209
210
211
212
213
214
215
216
217
218
219
220
221
222
223
224
225
226
227
228
229
230
231
232
233
234
235
236
237
238
239
240
241
242
243
244
245
246
247
248
249
250
251
252
253
254
255
256
257
258
259
260
261
262
263
264
265
266
267
268
269
270
271
272
273
274
275
276
277
278
279
280
281
282
283
284
285
286
287
288
289
290
291
292
293
294
295
296
297
298
299
300
301
302
303
304
305
306
307
308
309
310
311
312
313
314
315
316
317
318
319
320
321
322
323
324
325
326
327
328
329
330
331
332
333
334
335
336
337
338
339
340
341
342
343
344
345
346
347
348
349
350
351
352
353
354
355
356
357
358
359
360
361
362
363
364
365
366
367
368
369
370
371
372
373
374
375
376
377
378
379
380
381
382
383
384
385
386
387
388
389
390
391
392
393
394
395
396
397
398
399
400
401
402
403
404
405
406
407
408
409
410
411
412
413
414
415
416
417
418
419
420
421
422
423
424
425
426
427
428
429
430
431
432
433
434
435
436
437
438
439
440
441
442
443
444
445
446
447
448
449
450
451
452
453
454
455
456
457
458
459
460
461
462
463
464
465
466
467
468
469
470
471
472
473
474
475
476
477
478
479
480
481
482
483
484
485
486
487
488
489
490
491
492
493
494
495
496
497
498
499
500
501
502
503
504
505
506
507
508
509
510
511
512
513
514
515
516
517
518
519
520
521
522
523
524
525
526
527
528
529
530
531
532
533
534
535
536
537
538
539
540
541
542
543
544
545
546
547
548
549
550
551
552
553
554
555
556
557
558
559
560
561
562
563
564
565
566
567
568
569
570
571
572
573
574
575
576
577
578
579
580
581
582
583
584
585
586
587
588
589
590
591
592
593
594
595
596
597
598
599
600
601
602
603
604
605
606
607
608
609
610
611
612
613
614
615
616
617
618
619
620
621
622
623
624
625
626
627
628
629
630
631
632
633
634
635
636
637
638
639
640
641
642
643
644
645
646
647
648
649
650
651
652
653
654
655
656
657
658
659
660
661
662
663
664
665
666
667
668
669
670
671
672
673
674
675
676
677
678
679
680
681
682
683
684
685
686
687
688
689
690
691
692
693
694
695
696
697
698
699
700
701
702
703
704
705
706
707
708
709
710
711
712
713
714
715
716
717
718
719
720
721
722
723
724
725
726
727
728
729
730
731
732
733
734
735
736
737
738
739
740
741
742
743
744
745
746
747
748
749
750
751
752
753
754
755
756
757
758
759
760
761
762
763
764
765
766
767
768
769
770
771
772
773
774
775
776
777
778
779
780
781
782
783
784
785
786
787
788
789
790
791
792
793
794
795
796
797
798
799
800
801
802
803
804
805
806
807
808
809
810
811
812
813
814
815
816
817
818
819
820
821
822
823
824
825
826
827
828
829
830
831
832
833
834
835
836
837
838
839
840
841
842
843
844
845
846
847
848
849
850
851
852
853
854
855
856
857
858
859
860
861
862
863
864
865
866
867
868
869
870
871
872
873
874
875
876
877
878
879
880
881
882
883
884
885
886
887
888
889
890
891
892
893
894
895
896
897
898
899
900
901
902
903
904
905
906
907
908
909
910
911
912
913
914
915
916
917
918
919
920
921
922
923
924
925
926
927
928
929
930
931
932
933
934
935
936
937
938
939
940
941
942
943
944
945
946
947
948
949
950
951
952
953
954
955
956
957
958
959
960
961
962
963
964
965
966
967
968
969
970
971
972
973
974
975
976
977
978
979
980
981
982
983
984
985
986
987
988
989
990
991
992
993
994
995
996
997
998
999
1000
1001
1002
1003
1004
1005
1006
1007
1008
1009
1010
1011
1012
1013
1014
1015
1016
1017
1018
1019
1020
1021
1022
1023
1024
1025
1026
1027
1028
1029
1030
1031
1032
1033
1034
1035
1036
1037
1038
1039
1040
1041
1042
1043
1044
1045
1046
1047
1048
1049
1050
1051
1052
1053
1054
1055
1056
1057
1058
1059
1060
1061
1062
1063
1064
1065
1066
1067
1068
1069
1070
1071
1072
1073
1074
1075
1076
1077
1078
1079
1080
1081
1082
1083
1084
1085
1086
1087
1088
1089
1090
1091
1092
1093
1094
1095
1096
1097
1098
1099
1100
1101
1102
1103
1104
1105
1106
1107
1108
1109
1110
1111
1112
1113
1114
1115
1116
1117
1118
1119
1120
1121
1122
1123
1124
1125
1126
1127
1128
1129
1130
1131
1132
1133
1134
1135
1136
1137
1138
1139
1140
1141
1142
1143
1144
1145
1146
1147
1148
1149
1150
1151
1152
1153
1154
1155
1156
1157
1158
1159
1160
1161
1162
1163
1164
1165
1166
1167
1168
1169
1170
1171
1172
1173
1174
1175
1176
1177
1178
1179
1180
1181
1182
1183
1184
1185
1186
1187
1188
1189
1190
1191
1192
1193
1194
1195
1196
1197
1198
1199
1200
1201
1202
1203
1204
1205
1206
1207
1208
1209
1210
1211
1212
1213
1214
1215
1216
1217
1218
1219
1220
1221
1222
1223
1224
1225
1226
1227
1228
1229
1230
1231
1232
1233
1234
1235
1236
1237
1238
1239
1240
1241
1242
1243
1244
1245
1246
1247
1248
1249
1250
1251
1252
1253
1254
1255
1256
1257
1258
1259
1260
1261
1262
1263
1264
1265
1266
1267
1268
1269
1270
1271
1272
1273
1274
1275
1276
1277
1278
1279
1280
1281
1282
1283
1284
1285
1286
1287
1288
1289
1290
1291
1292
1293
1294
1295
1296
1297
1298
1299
1300
1301
1302
1303
1304
1305
1306
1307
1308
1309
1310
1311
1312
1313
1314
1315
1316
1317
1318
1319
1320
1321
1322
1323
1324
1325
1326
1327
1328
1329
1330
1331
1332
1333
1334
1335
1336
1337
1338
1339
1340
1341
1342
1343
1344
1345
1346
1347
1348
1349
1350
1351
1352
1353
1354
1355
1356
1357
1358
1359
1360
1361
1362
1363
1364
1365
1366
1367
1368
1369
1370
1371
1372
1373
1374
1375
1376
1377
1378
1379
1380
1381
1382
1383
1384
1385
1386
1387
1388
1389
1390
1391
1392
1393
1394
1395
1396
1397
1398
1399
1400
1401
1402
1403
1404
1405
1406
1407
1408
1409
1410
1411
1412
1413
1414
1415
1416
1417
1418
1419
1420
1421
1422
1423
1424
1425
1426
1427
1428
1429
1430
1431
1432
1433
1434
1435
1436
1437
1438
1439
1440
1441
1442
1443
1444
1445
1446
1447
1448
1449
1450
1451
1452
1453
1454
1455
1456
1457
1458
1459
1460
1461
1462
1463
1464
1465
1466
1467
1468
1469
1470
1471
1472
1473
1474
1475
1476
1477
1478
1479
1480
1481
1482
1483
1484
1485
1486
1487
1488
1489
1490
1491
1492
1493
1494
1495
1496
1497
1498
1499
1500
1501
1502
1503
1504
1505
1506
1507
1508
1509
1510
1511
1512
1513
1514
1515
1516
1517
1518
1519
1520
1521
1522
1523
1524
1525
1526
1527
1528
1529
1530
1531
1532
1533
1534
1535
1536
1537
1538
1539
1540
1541
1542
1543
1544
1545
1546
1547
1548
1549
1550
1551
1552
1553
1554
1555
1556
1557
1558
1559
1560
1561
1562
1563
1564
1565
1566
1567
1568
1569
1570
1571
1572
1573
1574
1575
1576
1577
1578
1579
1580
1581
1582
1583
1584
1585
1586
1587
1588
1589
1590
1591
1592
1593
1594
1595
1596
1597
1598
1599
1600
1601
1602
1603
1604
1605
1606
1607
1608
1609
1610
1611
1612
1613
1614
1615
1616
1617
1618
1619
1620
1621
1622
1623
1624
1625
1626
1627
1628
1629
1630
1631
1632
1633
1634
1635
1636
1637
1638
1639
1640
1641
1642
1643
1644
1645
1646
1647
1648
1649
1650
1651
1652
1653
1654
1655
1656
1657
1658
1659
1660
1661
1662
1663
1664
1665
1666
1667
1668
1669
1670
1671
1672
1673
1674
1675
1676
1677
1678
1679
1680
1681
1682
1683
1684
1685
1686
1687
1688
1689
1690
1691
1692
1693
1694
1695
1696
1697
1698
1699
1700
1701
1702
1703
1704
1705
1706
1707
1708
1709
1710
1711
1712
1713
1714
1715
1716
1717
1718
1719
1720
1721
1722
1723
1724
1725
1726
1727
1728
1729
1730
1731
1732
1733
1734
1735
1736
1737
1738
1739
1740
1741
1742
1743
1744
1745
1746
1747
1748
1749
1750
1751
1752
1753
1754
1755
1756
1757
1758
1759
1760
1761
1762
1763
1764
1765
1766
1767
1768
1769
1770
1771
1772
1773
1774
1775
1776
1777
1778
1779
1780
1781
1782
1783
1784
1785
1786
1787
1788
1789
1790
1791
1792
1793
1794
1795
1796
1797
1798
1799
1800
1801
1802
1803
1804
1805
1806
1807
1808
1809
1810
1811
1812
1813
1814
1815
1816
1817
1818
1819
1820
1821
1822
1823
1824
1825
1826
1827
1828
1829
1830
1831
1832
1833
1834
1835
1836
1837
1838
1839
1840
1841
1842
1843
1844
1845
1846
1847
1848
1849
1850
1851
1852
1853
1854
1855
1856
1857
1858
1859
1860
1861
1862
1863
1864
1865
1866
1867
1868
1869
1870
1871
1872
1873
1874
1875
1876
1877
1878
1879
1880
1881
1882
1883
1884
1885
1886
1887
1888
1889
1890
1891
1892
1893
1894
1895
1896
1897
1898
1899
1900
1901
1902
1903
1904
1905
1906
1907
1908
1909
1910
1911
1912
1913
1914
1915
1916
1917
1918
1919
1920
1921
1922
1923
1924
1925
1926
1927
1928
1929
1930
1931
1932
1933
1934
1935
1936
1937
1938
1939
1940
1941
1942
1943
1944
1945
1946
1947
1948
1949
1950
1951
1952
1953
1954
1955
1956
1957
1958
1959
1960
1961
1962
1963
1964
1965
1966
1967
1968
1969
1970
1971
1972
1973
1974
1975
1976
1977
1978
1979
1980
1981
1982
1983
1984
1985
1986
1987
1988
1989
1990
1991
1992
1993
1994
1995
1996
1997
1998
1999
2000
2001
2002
2003
2004
2005
2006
2007
2008
2009
2010
2011
2012
2013
2014
2015
2016
2017
2018
2019
2020
2021
2022
2023
2024
2025
2026
2027
2028
2029
2030
2031
2032
2033
2034
2035
2036
2037
2038
2039
2040
2041
2042
2043
2044
2045
2046
2047
2048
2049
2050
2051
2052
2053
2054
2055
2056
2057
2058
2059
2060
2061
2062
2063
2064
2065
2066
2067
2068
2069
2070
2071
2072
2073
2074
2075
2076
2077
2078
2079
2080
2081
2082
2083
2084
2085
2086
2087
2088
2089
2090
2091
2092
2093
2094
2095
2096
2097
2098
2099
2100
2101
2102
2103
2104
2105
2106
2107
2108
2109
2110
2111
2112
2113
2114
2115
2116
2117
2118
2119
2120
2121
2122
2123
2124
2125
2126
2127
2128
2129
2130
2131
2132
2133
2134
2135
2136
2137
2138
2139
2140
2141
2142
2143
2144
2145
2146
2147
2148
2149
2150
2151
2152
2153
2154
2155
2156
2157
2158
2159
2160
2161
2162
2163
2164
2165
2166
2167
2168
2169
2170
2171
2172
2173
2174
2175
2176
2177
2178
2179
2180
2181
2182
2183
2184
2185
2186
2187
2188
2189
2190
2191
2192
2193
2194
2195
2196
2197
2198
2199
2200
2201
2202
2203
2204
2205
2206
2207
2208
2209
2210
2211
2212
2213
2214
2215
2216
2217
2218
2219
2220
2221
2222
2223
2224
2225
2226
2227
2228
2229
2230
2231
2232
2233
2234
2235
2236
2237
2238
2239
2240
2241
2242
2243
2244
2245
2246
2247
2248
2249
2250
2251
2252
2253
2254
2255
2256
2257
2258
2259
2260
2261
2262
2263
2264
2265
2266
2267
2268
2269
2270
2271
2272
2273
2274
2275
2276
2277
2278
2279
2280
2281
2282
2283
2284
2285
2286
2287
2288
2289
2290
2291
2292
2293
2294
2295
2296
2297
2298
2299
2300
2301
2302
2303
2304
2305
2306
2307
2308
2309
2310
2311
2312
2313
2314
2315
2316
2317
2318
2319
2320
2321
2322
2323
2324
2325
2326
2327
2328
2329
2330
2331
2332
2333
2334
2335
2336
2337
2338
2339
2340
2341
2342
2343
2344
2345
2346
2347
2348
2349
2350
2351
2352
2353
2354
2355
2356
2357
2358
2359
2360
2361
2362
2363
2364
2365
2366
2367
2368
2369
2370
2371
2372
2373
2374
2375
2376
2377
2378
2379
2380
2381
2382
2383
2384
2385
2386
2387
2388
2389
2390
2391
2392
2393
2394
2395
2396
2397
2398
2399
2400
2401
2402
2403
2404
2405
2406
2407
2408
2409
2410
2411
2412
2413
2414
2415
2416
2417
2418
2419
2420
2421
2422
2423
2424
2425
2426
2427
2428
2429
2430
2431
2432
2433
2434
2435
2436
2437
2438
2439
2440
2441
2442
2443
2444
2445
2446
2447
2448
2449
2450
2451
2452
2453
2454
2455
2456
2457
2458
2459
2460
2461
2462
2463
2464
2465
2466
2467
2468
2469
2470
2471
2472
2473
2474
2475
2476
2477
2478
2479
2480
2481
2482
2483
2484
2485
2486
2487
2488
2489
2490
2491
2492
2493
2494
2495
2496
2497
2498
2499
2500
2501
2502
2503
2504
2505
2506
2507
2508
2509
2510
2511
2512
2513
2514
2515
2516
2517
2518
2519
2520
2521
2522
2523
2524
2525
2526
2527
2528
2529
2530
2531
2532
2533
2534
2535
2536
2537
2538
2539
2540
2541
2542
2543
2544
2545
2546
2547
2548
2549
2550
2551
2552
2553
2554
2555
2556
2557
2558
2559
2560
2561
2562
2563
2564
2565
2566
2567
2568
2569
2570
2571
2572
2573
2574
2575
2576
2577
2578
2579
2580
2581
2582
2583
2584
2585
2586
2587
2588
2589
2590
2591
2592
2593
2594
2595
2596
2597
2598
2599
2600
2601
2602
2603
2604
2605
2606
2607
2608
2609
2610
2611
2612
2613
2614
2615
2616
2617
2618
2619
2620
2621
2622
2623
2624
2625
2626
2627
2628
2629
2630
2631
2632
2633
2634
2635
2636
2637
2638
2639
2640
2641
2642
2643
2644
2645
2646
2647
2648
2649
2650
2651
2652
2653
2654
2655
2656
2657
2658
2659
2660
2661
2662
2663
2664
2665
2666
2667
2668
2669
2670
2671
2672
2673
2674
2675
2676
2677
2678
2679
2680
2681
2682
2683
2684
2685
2686
2687
2688
2689
2690
2691
2692
2693
2694
2695
2696
2697
2698
2699
2700
2701
2702
2703
2704
2705
2706
2707
2708
2709
2710
2711
2712
2713
2714
2715
2716
2717
2718
2719
2720
2721
2722
2723
2724
2725
2726
2727
2728
2729
2730
2731
2732
2733
2734
2735
2736
2737
2738
2739
2740
2741
2742
2743
2744
2745
2746
2747
2748
2749
2750
2751
2752
2753
2754
2755
2756
2757
2758
2759
2760
2761
2762
2763
2764
2765
2766
2767
2768
2769
2770
2771
2772
2773
2774
2775
2776
2777
2778
2779
2780
2781
2782
2783
2784
2785
2786
2787
2788
2789
2790
2791
2792
2793
2794
2795
2796
2797
2798
2799
2800
2801
2802
2803
2804
2805
2806
2807
2808
2809
2810
2811
2812
2813
2814
2815
2816
2817
2818
2819
2820
2821
2822
2823
2824
2825
2826
2827
2828
2829
2830
2831
2832
2833
2834
2835
2836
2837
2838
2839
2840
2841
2842
2843
2844
2845
2846
2847
2848
2849
2850
2851
2852
2853
2854
2855
2856
2857
2858
2859
2860
2861
2862
2863
2864
2865
2866
2867
2868
2869
2870
2871
2872
2873
2874
2875
2876
2877
2878
2879
2880
2881
2882
2883
2884
2885
2886
2887
2888
2889
2890
2891
2892
2893
2894
2895
2896
2897
2898
2899
2900
2901
2902
2903
2904
2905
2906
2907
2908
2909
2910
2911
2912
2913
2914
2915
2916
2917
2918
2919
2920
2921
2922
2923
2924
2925
2926
2927
2928
2929
2930
2931
2932
2933
2934
2935
2936
2937
2938
2939
2940
2941
2942
2943
2944
2945
2946
2947
2948
2949
2950
2951
2952
2953
2954
2955
2956
2957
2958
2959
2960
2961
2962
2963
2964
2965
2966
2967
2968
2969
2970
2971
2972
2973
2974
2975
2976
2977
2978
2979
2980
2981
2982
2983
2984
2985
2986
2987
2988
2989
2990
2991
2992
2993
2994
2995
2996
2997
2998
2999
3000
3001
3002
3003
3004
3005
3006
3007
3008
3009
3010
3011
3012
3013
3014
3015
3016
3017
3018
3019
3020
3021
3022
3023
3024
3025
3026
3027
3028
3029
3030
3031
3032
3033
3034
3035
3036
3037
3038
3039
3040
3041
3042
3043
3044
3045
3046
3047
3048
3049
3050
3051
3052
3053
3054
3055
3056
3057
3058
3059
3060
3061
3062
3063
3064
3065
3066
3067
3068
3069
3070
3071
3072
3073
3074
3075
3076
3077
3078
3079
3080
3081
3082
3083
3084
3085
3086
3087
3088
3089
3090
3091
3092
3093
3094
3095
3096
3097
3098
3099
3100
3101
3102
3103
3104
3105
3106
3107
3108
3109
3110
3111
3112
3113
3114
3115
3116
3117
3118
3119
3120
3121
3122
3123
3124
3125
3126
3127
3128
3129
3130
3131
3132
3133
3134
3135
3136
3137
3138
3139
3140
3141
3142
3143
3144
3145
3146
3147
3148
3149
3150
3151
3152
3153
3154
3155
3156
3157
3158
3159
3160
3161
3162
3163
3164
3165
3166
3167
3168
3169
3170
3171
3172
3173
3174
3175
3176
3177
3178
3179
3180
3181
3182
3183
3184
3185
3186
3187
3188
3189
3190
3191
3192
3193
3194
3195
3196
3197
3198
3199
3200
3201
3202
3203
3204
3205
3206
3207
3208
3209
3210
3211
3212
3213
3214
3215
3216
3217
3218
3219
3220
3221
3222
3223
3224
3225
3226
3227
3228
3229
3230
3231
3232
3233
3234
3235
3236
3237
3238
3239
3240
3241
3242
3243
3244
3245
3246
3247
3248
3249
3250
3251
3252
3253
3254
3255
3256
3257
3258
3259
3260
3261
3262
3263
3264
3265
3266
3267
3268
3269
3270
3271
3272
3273
3274
3275
3276
3277
3278
3279
3280
3281
3282
3283
3284
3285
3286
3287
3288
3289
3290
3291
3292
3293
3294
3295
3296
3297
3298
3299
3300
3301
3302
3303
3304
3305
3306
3307
3308
3309
3310
3311
3312
3313
3314
3315
3316
3317
3318
3319
3320
3321
3322
3323
3324
3325
3326
3327
3328
3329
3330
3331
3332
3333
3334
3335
3336
3337
3338
3339
3340
3341
3342
3343
3344
3345
3346
3347
3348
3349
3350
3351
3352
3353
3354
3355
3356
3357
3358
3359
3360
3361
3362
3363
3364
3365
3366
3367
3368
3369
3370
3371
3372
3373
3374
3375
3376
3377
3378
3379
3380
3381
3382
3383
3384
3385
3386
3387
3388
3389
3390
3391
3392
3393
3394
3395
3396
3397
3398
3399
3400
3401
3402
3403
3404
3405
3406
3407
3408
3409
3410
3411
3412
3413
3414
3415
3416
3417
3418
3419
3420
3421
3422
3423
3424
3425
3426
3427
3428
3429
3430
3431
3432
3433
3434
3435
3436
3437
3438
3439
3440
3441
3442
3443
3444
3445
3446
3447
3448
3449
3450
3451
3452
3453
3454
3455
3456
3457
3458
3459
3460
3461
3462
3463
3464
3465
3466
3467
3468
3469
3470
3471
3472
3473
3474
3475
3476
3477
3478
3479
3480
3481
3482
3483
3484
3485
3486
3487
3488
3489
3490
3491
3492
3493
3494
3495
3496
3497
3498
3499
3500
3501
3502
3503
3504
3505
3506
3507
3508
3509
3510
3511
3512
3513
3514
3515
3516
3517
3518
3519
3520
3521
3522
3523
3524
3525
3526
3527
3528
3529
3530
3531
3532
3533
3534
3535
3536
3537
3538
3539
3540
3541
3542
3543
3544
3545
3546
3547
3548
3549
3550
3551
3552
3553
3554
3555
3556
3557
3558
3559
3560
3561
3562
3563
3564
3565
3566
3567
3568
3569
3570
3571
3572
3573
3574
3575
3576
3577
3578
3579
3580
3581
3582
3583
3584
3585
3586
3587
3588
3589
3590
3591
3592
3593
3594
3595
3596
3597
3598
3599
3600
3601
3602
3603
3604
3605
3606
3607
3608
3609
3610
3611
3612
3613
3614
3615
3616
3617
3618
3619
3620
3621
3622
3623
3624
3625
3626
3627
3628
3629
3630
3631
3632
3633
3634
3635
3636
3637
3638
3639
3640
3641
3642
3643
3644
3645
3646
3647
3648
3649
3650
3651
3652
3653
3654
3655
3656
3657
3658
3659
3660
3661
3662
3663
3664
3665
3666
3667
3668
3669
3670
3671
3672
3673
3674
3675
3676
3677
3678
3679
3680
3681
3682
3683
3684
3685
3686
3687
3688
3689
3690
3691
3692
3693
3694
3695
3696
3697
3698
3699
3700
3701
3702
3703
3704
3705
3706
3707
3708
3709
3710
3711
3712
3713
3714
3715
3716
3717
3718
3719
3720
3721
3722
3723
3724
3725
3726
3727
3728
3729
3730
3731
3732
3733
3734
3735
3736
3737
3738
3739
3740
3741
3742
3743
3744
3745
3746
3747
3748
3749
3750
3751
3752
3753
3754
3755
3756
3757
3758
3759
3760
3761
3762
3763
3764
3765
3766
3767
3768
3769
3770
3771
3772
3773
3774
3775
3776
3777
3778
3779
3780
3781
3782
3783
3784
3785
3786
3787
3788
3789
3790
3791
3792
3793
3794
3795
3796
3797
3798
3799
3800
3801
3802
3803
3804
3805
3806
3807
3808
3809
3810
3811
3812
3813
3814
3815
3816
3817
3818
3819
3820
3821
3822
3823
3824
3825
3826
3827
3828
3829
3830
3831
3832
3833
3834
3835
3836
3837
3838
3839
3840
3841
3842
3843
3844
3845
3846
3847
3848
3849
3850
3851
3852
3853
3854
3855
3856
3857
3858
3859
3860
3861
3862
3863
3864
3865
3866
3867
3868
3869
3870
3871
3872
3873
3874
3875
3876
3877
3878
3879
3880
3881
3882
3883
3884
3885
3886
3887
3888
3889
3890
3891
3892
3893
3894
3895
3896
3897
3898
3899
3900
3901
3902
3903
3904
3905
3906
3907
3908
3909
3910
3911
3912
3913
3914
3915
3916
3917
3918
3919
3920
3921
3922
3923
3924
3925
3926
3927
3928
3929
3930
3931
3932
3933
3934
3935
3936
3937
3938
3939
3940
3941
3942
3943
3944
3945
3946
3947
3948
3949
3950
3951
3952
3953
3954
3955
3956
3957
3958
3959
3960
3961
3962
3963
3964
3965
3966
3967
3968
3969
3970
3971
3972
3973
3974
3975
3976
3977
3978
3979
3980
3981
3982
3983
3984
3985
3986
3987
3988
3989
3990
3991
3992
3993
3994
3995
3996
3997
3998
3999
4000
4001
4002
4003
4004
4005
4006
4007
4008
4009
4010
4011
4012
4013
4014
4015
4016
4017
4018
4019
4020
4021
4022
4023
4024
4025
4026
4027
4028
4029
4030
4031
4032
4033
4034
4035
4036
4037
4038
4039
4040
4041
4042
4043
4044
4045
4046
4047
4048
4049
4050
4051
4052
4053
4054
4055
4056
4057
4058
4059
4060
4061
4062
4063
4064
4065
4066
4067
4068
4069
4070
4071
4072
4073
4074
4075
4076
4077
4078
4079
4080
4081
4082
4083
4084
4085
4086
4087
4088
4089
4090
4091
4092
4093
4094
4095
4096
4097
4098
4099
4100
4101
4102
4103
4104
4105
4106
4107
4108
4109
4110
4111
4112
4113
4114
4115
4116
4117
4118
4119
4120
4121
4122
4123
4124
4125
4126
4127
4128
4129
4130
4131
4132
4133
4134
4135
4136
4137
4138
4139
4140
4141
4142
4143
4144
4145
4146
4147
4148
4149
4150
4151
4152
4153
4154
4155
4156
4157
4158
4159
4160
4161
4162
4163
4164
4165
4166
4167
4168
4169
4170
4171
4172
4173
4174
4175
4176
4177
4178
4179
4180
4181
4182
4183
4184
4185
4186
4187
4188
4189
4190
4191
4192
4193
4194
4195
4196
4197
4198
4199
4200
4201
4202
4203
4204
4205
4206
4207
4208
4209
4210
4211
4212
4213
4214
4215
4216
4217
4218
4219
4220
4221
4222
4223
4224
4225
4226
4227
4228
4229
4230
4231
4232
4233
4234
4235
4236
4237
4238
4239
4240
4241
4242
4243
4244
4245
4246
4247
4248
4249
4250
4251
4252
4253
4254
4255
4256
4257
4258
4259
4260
4261
4262
4263
4264
4265
4266
4267
4268
4269
4270
4271
4272
4273
4274
4275
4276
4277
4278
4279
4280
4281
4282
4283
4284
4285
4286
4287
4288
4289
4290
4291
4292
4293
4294
4295
4296
4297
4298
4299
4300
4301
4302
4303
4304
4305
4306
4307
4308
4309
4310
4311
4312
4313
4314
4315
4316
4317
4318
4319
4320
4321
4322
4323
4324
4325
4326
4327
4328
4329
4330
4331
4332
4333
4334
4335
4336
4337
4338
4339
4340
4341
4342
4343
4344
4345
4346
4347
4348
4349
4350
4351
4352
4353
4354
4355
4356
4357
4358
4359
4360
4361
4362
4363
4364
4365
4366
4367
4368
4369
4370
4371
4372
4373
4374
4375
4376
4377
4378
4379
4380
4381
4382
4383
4384
4385
4386
4387
4388
4389
4390
4391
4392
4393
4394
4395
4396
4397
4398
4399
4400
4401
4402
4403
4404
4405
4406
4407
4408
4409
4410
4411
4412
4413
4414
4415
4416
4417
4418
4419
4420
4421
4422
4423
4424
4425
4426
4427
4428
4429
4430
4431
4432
4433
4434
4435
4436
4437
4438
4439
4440
4441
4442
4443
4444
4445
4446
4447
4448
4449
4450
4451
4452
4453
4454
4455
4456
4457
4458
4459
4460
4461
4462
4463
4464
4465
4466
4467
4468
4469
4470
4471
4472
4473
4474
4475
4476
4477
4478
4479
4480
4481
4482
4483
4484
4485
4486
4487
4488
4489
4490
4491
4492
4493
4494
4495
4496
4497
4498
4499
4500
4501
4502
4503
4504
4505
4506
4507
4508
4509
4510
4511
4512
4513
4514
4515
4516
4517
4518
4519
4520
4521
4522
4523
4524
4525
4526
4527
4528
4529
4530
4531
4532
4533
4534
4535
4536
4537
4538
4539
4540
4541
4542
4543
4544
4545
4546
4547
4548
4549
4550
4551
4552
4553
4554
4555
4556
4557
4558
4559
4560
4561
4562
4563
4564
4565
4566
4567
4568
4569
4570
4571
4572
4573
4574
4575
4576
4577
4578
4579
4580
4581
4582
4583
4584
4585
4586
4587
4588
4589
4590
4591
4592
4593
4594
4595
4596
4597
4598
4599
4600
4601
4602
4603
4604
4605
4606
4607
4608
4609
4610
4611
4612
4613
4614
4615
4616
4617
4618
4619
4620
4621
4622
4623
4624
4625
4626
4627
4628
4629
4630
4631
4632
4633
4634
4635
4636
4637
4638
4639
4640
4641
4642
4643
4644
4645
4646
4647
4648
4649
4650
4651
4652
4653
4654
4655
4656
4657
4658
4659
4660
4661
4662
4663
4664
4665
4666
4667
4668
4669
4670
4671
4672
4673
4674
4675
4676
4677
4678
4679
4680
4681
4682
4683
4684
4685
4686
4687
4688
4689
4690
4691
4692
4693
4694
4695
4696
4697
4698
4699
4700
4701
4702
4703
4704
4705
4706
4707
4708
4709
4710
4711
4712
4713
4714
4715
4716
4717
4718
4719
4720
4721
4722
4723
4724
4725
4726
4727
4728
4729
4730
4731
4732
4733
4734
4735
4736
4737
4738
4739
4740
4741
4742
4743
4744
4745
4746
4747
4748
4749
4750
4751
4752
4753
4754
4755
4756
4757
4758
4759
4760
4761
4762
4763
4764
4765
4766
4767
4768
4769
4770
4771
4772
4773
4774
4775
4776
4777
4778
4779
4780
4781
4782
4783
4784
4785
4786
4787
4788
4789
4790
4791
4792
4793
4794
4795
4796
4797
4798
4799
4800
4801
4802
4803
4804
4805
4806
4807
4808
4809
4810
4811
4812
4813
4814
4815
4816
4817
4818
4819
4820
4821
4822
4823
4824
4825
4826
4827
4828
4829
4830
4831
4832
4833
4834
4835
4836
4837
4838
4839
4840
4841
4842
4843
4844
4845
4846
4847
4848
4849
4850
4851
4852
4853
4854
4855
4856
4857
4858
4859
4860
4861
4862
4863
4864
4865
4866
4867
4868
4869
4870
4871
4872
4873
4874
4875
4876
4877
4878
4879
4880
4881
4882
4883
4884
4885
4886
4887
4888
4889
4890
4891
4892
4893
4894
4895
4896
4897
4898
4899
4900
4901
4902
4903
4904
4905
4906
4907
4908
4909
4910
4911
4912
4913
4914
4915
4916
4917
4918
4919
4920
4921
4922
4923
4924
4925
4926
4927
4928
4929
4930
4931
4932
4933
4934
4935
4936
4937
4938
4939
4940
4941
4942
4943
4944
4945
4946
4947
4948
4949
4950
4951
4952
4953
4954
4955
4956
4957
4958
4959
4960
4961
4962
4963
4964
4965
4966
4967
4968
4969
4970
4971
4972
4973
4974
4975
4976
4977
4978
4979
4980
4981
4982
4983
4984
4985
4986
4987
4988
4989
4990
4991
4992
4993
4994
4995
4996
4997
4998
4999
5000
5001
5002
5003
5004
5005
5006
5007
5008
5009
5010
5011
5012
5013
5014
5015
5016
5017
5018
5019
5020
5021
5022
5023
5024
5025
5026
5027
5028
5029
5030
5031
5032
5033
5034
5035
5036
5037
5038
5039
5040
5041
5042
5043
5044
5045
5046
5047
5048
5049
5050
5051
5052
5053
5054
5055
5056
5057
5058
5059
5060
5061
5062
5063
5064
5065
5066
5067
5068
5069
5070
5071
5072
5073
5074
5075
5076
5077
5078
5079
5080
5081
5082
5083
5084
5085
5086
5087
5088
5089
5090
5091
5092
5093
5094
5095
5096
5097
5098
5099
5100
5101
5102
5103
5104
5105
5106
5107
5108
5109
5110
5111
5112
5113
5114
5115
5116
5117
5118
5119
5120
5121
5122
5123
5124
5125
5126
5127
5128
5129
5130
5131
5132
5133
5134
5135
5136
5137
5138
5139
5140
5141
5142
5143
5144
5145
5146
5147
5148
5149
5150
5151
5152
5153
5154
5155
5156
5157
5158
5159
5160
5161
5162
5163
5164
5165
5166
5167
5168
5169
5170
5171
5172
5173
5174
5175
5176
5177
5178
5179
5180
5181
5182
5183
5184
5185
5186
5187
5188
5189
5190
5191
5192
5193
5194
5195
5196
5197
5198
5199
5200
5201
5202
5203
5204
5205
5206
5207
5208
5209
5210
5211
5212
5213
5214
5215
5216
5217
5218
5219
5220
5221
5222
5223
5224
5225
5226
5227
5228
5229
5230
5231
5232
5233
5234
5235
5236
5237
5238
5239
5240
5241
5242
5243
5244
5245
5246
5247
5248
5249
5250
5251
5252
5253
5254
5255
5256
5257
5258
5259
5260
5261
5262
5263
5264
5265
5266
5267
5268
5269
5270
5271
5272
5273
5274
5275
5276
5277
5278
5279
5280
5281
5282
5283
5284
5285
5286
5287
5288
5289
5290
5291
5292
5293
5294
5295
5296
5297
5298
5299
5300
5301
5302
5303
5304
5305
5306
5307
5308
5309
5310
5311
5312
5313
5314
5315
5316
5317
5318
5319
5320
5321
5322
5323
5324
5325
5326
5327
5328
5329
5330
5331
5332
5333
5334
5335
5336
5337
5338
5339
5340
5341
5342
5343
5344
5345
5346
5347
5348
5349
5350
5351
5352
5353
5354
5355
5356
5357
5358
5359
5360
5361
5362
5363
5364
5365
5366
5367
5368
5369
5370
5371
5372
5373
5374
5375
5376
5377
5378
5379
5380
5381
5382
5383
5384
5385
5386
5387
5388
5389
5390
5391
5392
5393
5394
5395
5396
5397
5398
5399
5400
5401
5402
5403
5404
5405
5406
5407
5408
5409
5410
5411
5412
5413
5414
5415
5416
5417
5418
5419
5420
5421
5422
5423
5424
5425
5426
5427
5428
5429
5430
5431
5432
5433
5434
5435
5436
5437
5438
5439
5440
5441
5442
5443
5444
5445
5446
5447
5448
5449
5450
5451
5452
5453
5454
5455
5456
5457
5458
5459
5460
5461
5462
5463
5464
5465
5466
5467
5468
5469
5470
5471
5472
5473
5474
5475
5476
5477
5478
5479
5480
5481
5482
5483
5484
5485
5486
5487
5488
5489
5490
5491
5492
5493
5494
5495
5496
5497
5498
5499
5500
5501
5502
5503
5504
5505
5506
5507
5508
5509
5510
5511
5512
5513
5514
5515
5516
5517
5518
5519
5520
5521
5522
5523
5524
5525
5526
5527
5528
5529
5530
5531
5532
5533
5534
5535
5536
5537
5538
5539
5540
5541
5542
5543
5544
5545
5546
5547
5548
5549
5550
5551
5552
5553
5554
5555
5556
5557
5558
5559
5560
5561
5562
5563
5564
5565
5566
5567
5568
5569
5570
5571
5572
5573
5574
5575
5576
5577
5578
5579
5580
5581
5582
5583
5584
5585
5586
5587
5588
5589
5590
5591
5592
5593
5594
5595
5596
5597
5598
5599
5600
5601
5602
5603
5604
5605
5606
5607
5608
5609
5610
5611
5612
5613
5614
5615
5616
5617
5618
5619
5620
5621
5622
5623
5624
5625
5626
5627
5628
5629
5630
5631
5632
5633
5634
5635
5636
5637
5638
5639
5640
5641
5642
5643
5644
5645
5646
5647
5648
5649
5650
5651
5652
5653
5654
5655
5656
5657
5658
5659
5660
5661
5662
5663
5664
5665
5666
5667
5668
5669
5670
5671
5672
5673
5674
5675
5676
5677
5678
5679
5680
5681
5682
5683
5684
5685
5686
5687
5688
5689
5690
5691
5692
5693
5694
5695
5696
5697
5698
5699
5700
5701
5702
5703
5704
5705
5706
5707
5708
5709
5710
5711
5712
5713
5714
5715
5716
5717
5718
5719
5720
5721
5722
5723
5724
5725
5726
5727
5728
5729
5730
5731
5732
5733
5734
5735
5736
5737
5738
5739
5740
5741
5742
5743
5744
5745
5746
5747
5748
5749
5750
5751
5752
5753
5754
5755
5756
5757
5758
5759
5760
5761
5762
5763
5764
5765
5766
5767
5768
5769
5770
5771
5772
5773
5774
5775
5776
5777
5778
5779
5780
5781
5782
5783
5784
5785
5786
5787
5788
5789
5790
5791
5792
5793
5794
5795
5796
5797
5798
5799
5800
5801
5802
5803
5804
5805
5806
5807
5808
5809
5810
5811
5812
5813
5814
5815
5816
5817
5818
5819
5820
5821
5822
5823
5824
5825
5826
5827
5828
5829
5830
5831
5832
5833
5834
5835
5836
5837
5838
5839
5840
5841
5842
5843
5844
5845
5846
5847
5848
5849
5850
5851
5852
5853
5854
5855
5856
5857
5858
5859
5860
5861
5862
5863
5864
5865
5866
5867
5868
5869
5870
5871
5872
5873
5874
5875
5876
5877
5878
5879
5880
5881
5882
5883
5884
5885
5886
5887
5888
5889
5890
5891
5892
5893
5894
5895
5896
5897
5898
5899
5900
5901
5902
5903
5904
5905
5906
5907
5908
5909
5910
5911
5912
5913
5914
5915
5916
5917
5918
5919
5920
5921
5922
5923
5924
5925
5926
5927
5928
5929
5930
5931
5932
5933
5934
5935
5936
5937
5938
5939
5940
5941
5942
5943
5944
5945
5946
5947
5948
5949
5950
5951
5952
5953
5954
5955
5956
5957
5958
5959
5960
5961
5962
5963
5964
5965
5966
5967
5968
5969
5970
5971
5972
5973
5974
5975
5976
5977
5978
5979
5980
5981
5982
5983
5984
5985
5986
5987
5988
5989
5990
5991
5992
5993
5994
5995
5996
5997
5998
5999
6000
6001
6002
6003
6004
6005
6006
6007
6008
6009
6010
6011
6012
6013
6014
6015
6016
6017
6018
6019
6020
6021
6022
6023
6024
6025
6026
6027
6028
6029
6030
6031
6032
6033
6034
6035
6036
6037
6038
6039
6040
6041
6042
6043
6044
6045
6046
6047
6048
6049
6050
6051
6052
6053
6054
6055
6056
6057
6058
6059
6060
6061
6062
6063
6064
6065
6066
6067
6068
6069
6070
6071
6072
6073
6074
6075
6076
6077
6078
6079
6080
6081
6082
6083
6084
6085
6086
6087
6088
6089
6090
6091
6092
6093
6094
6095
6096
6097
6098
6099
6100
6101
6102
6103
6104
6105
6106
6107
6108
6109
6110
6111
6112
6113
6114
6115
6116
6117
6118
6119
6120
6121
6122
6123
6124
6125
6126
6127
6128
6129
6130
6131
6132
6133
6134
6135
6136
6137
6138
6139
6140
6141
6142
6143
6144
6145
6146
6147
6148
6149
6150
6151
6152
6153
6154
6155
6156
6157
6158
6159
6160
6161
6162
6163
6164
6165
6166
6167
6168
6169
6170
6171
6172
6173
6174
6175
6176
6177
6178
6179
6180
6181
6182
6183
6184
6185
6186
6187
6188
6189
6190
6191
6192
6193
6194
6195
6196
6197
6198
6199
6200
6201
6202
6203
6204
6205
6206
6207
6208
6209
6210
6211
6212
6213
6214
6215
6216
6217
6218
6219
6220
6221
6222
6223
6224
6225
6226
6227
6228
6229
6230
6231
6232
6233
6234
6235
6236
6237
6238
6239
6240
6241
6242
6243
6244
6245
6246
6247
6248
6249
6250
6251
6252
6253
6254
6255
6256
6257
6258
6259
6260
6261
6262
6263
6264
6265
6266
6267
6268
6269
6270
6271
6272
6273
6274
6275
6276
6277
6278
6279
6280
6281
6282
6283
6284
6285
6286
6287
6288
6289
6290
6291
6292
6293
6294
6295
6296
6297
6298
6299
6300
6301
6302
6303
6304
6305
6306
6307
6308
6309
6310
6311
6312
6313
6314
6315
6316
6317
6318
6319
6320
6321
6322
6323
6324
6325
6326
6327
6328
6329
6330
6331
6332
6333
6334
6335
6336
6337
6338
6339
6340
6341
6342
6343
6344
6345
6346
6347
6348
6349
6350
6351
6352
6353
6354
6355
6356
6357
6358
6359
6360
6361
6362
6363
6364
6365
6366
6367
6368
6369
6370
6371
6372
6373
6374
6375
6376
6377
6378
6379
6380
6381
6382
6383
6384
6385
6386
6387
6388
6389
6390
6391
6392
6393
6394
6395
6396
6397
6398
6399
6400
6401
6402
6403
6404
6405
6406
6407
6408
6409
6410
6411
6412
6413
6414
6415
6416
6417
6418
6419
6420
6421
6422
6423
6424
6425
6426
6427
6428
6429
6430
6431
6432
6433
6434
6435
6436
6437
6438
6439
6440
6441
6442
6443
6444
6445
6446
6447
6448
6449
6450
6451
6452
6453
6454
6455
6456
6457
6458
6459
6460
6461
6462
6463
6464
6465
6466
6467
6468
6469
6470
6471
6472
6473
6474
6475
6476
6477
6478
6479
6480
6481
6482
6483
6484
6485
6486
6487
6488
6489
6490
6491
6492
6493
6494
6495
6496
6497
6498
6499
6500
6501
6502
6503
6504
6505
6506
6507
6508
6509
6510
6511
6512
6513
6514
6515
6516
6517
6518
6519
6520
6521
6522
6523
6524
6525
6526
6527
6528
6529
6530
6531
6532
6533
6534
6535
6536
6537
6538
6539
6540
6541
6542
6543
6544
6545
6546
6547
6548
6549
6550
6551
6552
6553
6554
6555
6556
6557
6558
6559
6560
6561
6562
6563
6564
6565
6566
6567
6568
6569
6570
6571
6572
6573
6574
6575
6576
6577
6578
6579
6580
6581
6582
6583
6584
6585
6586
6587
6588
6589
6590
6591
6592
6593
6594
6595
6596
6597
6598
6599
6600
6601
6602
6603
6604
6605
6606
6607
6608
6609
6610
6611
6612
6613
6614
6615
6616
6617
6618
6619
6620
6621
6622
6623
6624
6625
6626
6627
6628
6629
6630
6631
6632
6633
6634
6635
6636
6637
6638
6639
6640
6641
6642
6643
6644
6645
6646
6647
6648
6649
6650
6651
6652
6653
6654
6655
6656
6657
6658
6659
6660
6661
6662
6663
6664
6665
6666
6667
6668
6669
6670
6671
6672
6673
6674
6675
6676
6677
6678
6679
6680
6681
6682
6683
6684
6685
6686
6687
6688
6689
6690
6691
6692
6693
6694
6695
6696
6697
6698
6699
6700
6701
6702
6703
6704
6705
6706
6707
6708
6709
6710
6711
6712
6713
6714
6715
6716
6717
6718
6719
6720
6721
6722
6723
6724
6725
6726
6727
6728
6729
6730
6731
6732
6733
6734
6735
6736
6737
6738
6739
6740
6741
6742
6743
6744
6745
6746
6747
6748
6749
6750
6751
6752
6753
6754
6755
6756
6757
6758
6759
6760
6761
6762
6763
6764
6765
6766
6767
6768
6769
6770
6771
6772
6773
6774
6775
6776
6777
6778
6779
6780
6781
6782
6783
6784
6785
6786
6787
6788
6789
6790
6791
6792
6793
6794
6795
6796
6797
6798
6799
6800
6801
6802
6803
6804
6805
6806
6807
6808
6809
6810
6811
6812
6813
6814
6815
6816
6817
6818
6819
6820
6821
6822
6823
6824
6825
6826
6827
6828
6829
6830
6831
6832
6833
6834
6835
6836
6837
6838
6839
6840
6841
6842
6843
6844
6845
6846
6847
6848
6849
6850
6851
6852
6853
6854
6855
6856
6857
6858
6859
6860
6861
6862
6863
6864
6865
6866
6867
6868
6869
6870
6871
6872
6873
6874
6875
6876
6877
6878
6879
6880
6881
6882
6883
6884
6885
6886
6887
6888
6889
6890
6891
6892
6893
6894
6895
6896
6897
6898
6899
6900
6901
6902
6903
6904
6905
6906
6907
6908
6909
6910
6911
6912
6913
6914
6915
6916
6917
6918
6919
6920
6921
6922
6923
6924
6925
6926
6927
6928
6929
6930
6931
6932
6933
6934
6935
6936
6937
6938
6939
6940
6941
6942
6943
6944
6945
6946
6947
6948
6949
6950
6951
6952
6953
6954
6955
6956
6957
6958
6959
6960
6961
6962
6963
6964
6965
6966
6967
6968
6969
6970
6971
6972
6973
6974
6975
6976
6977
6978
6979
6980
6981
6982
6983
6984
6985
6986
6987
6988
6989
6990
6991
6992
6993
6994
6995
6996
6997
6998
6999
7000
7001
7002
7003
7004
7005
7006
7007
7008
7009
7010
7011
7012
7013
7014
7015
7016
7017
7018
7019
7020
7021
7022
7023
7024
7025
7026
7027
7028
7029
7030
7031
7032
7033
7034
7035
7036
7037
7038
7039
7040
7041
7042
7043
7044
7045
7046
7047
7048
7049
7050
7051
7052
7053
7054
7055
7056
7057
7058
7059
7060
7061
7062
7063
7064
7065
7066
7067
7068
7069
7070
7071
7072
7073
7074
7075
7076
7077
7078
7079
7080
7081
7082
7083
7084
7085
7086
7087
7088
7089
7090
7091
7092
7093
7094
7095
7096
7097
7098
7099
7100
7101
7102
7103
7104
7105
7106
7107
7108
7109
7110
7111
7112
7113
7114
7115
7116
7117
7118
7119
7120
7121
7122
7123
7124
7125
7126
7127
7128
7129
7130
7131
7132
7133
7134
7135
7136
7137
7138
7139
7140
7141
7142
7143
7144
7145
7146
7147
7148
7149
7150
7151
7152
7153
7154
7155
7156
7157
7158
7159
7160
7161
7162
7163
7164
7165
7166
7167
7168
7169
7170
7171
7172
7173
7174
7175
7176
7177
7178
7179
7180
7181
7182
7183
7184
7185
7186
7187
7188
7189
7190
7191
7192
7193
7194
7195
7196
7197
7198
7199
7200
7201
7202
7203
7204
7205
7206
7207
7208
7209
7210
7211
7212
7213
7214
7215
7216
7217
7218
7219
7220
7221
7222
7223
7224
7225
7226
7227
7228
7229
7230
7231
7232
7233
7234
7235
7236
7237
7238
7239
7240
7241
7242
7243
7244
7245
7246
7247
7248
7249
7250
7251
7252
7253
7254
7255
7256
7257
7258
7259
7260
7261
7262
7263
7264
7265
7266
7267
7268
7269
7270
7271
7272
7273
7274
7275
7276
7277
7278
7279
7280
7281
7282
7283
7284
7285
7286
7287
7288
7289
7290
7291
7292
7293
7294
7295
7296
7297
7298
7299
7300
7301
7302
7303
7304
7305
7306
7307
7308
7309
7310
7311
7312
7313
7314
7315
7316
7317
7318
7319
7320
7321
7322
7323
7324
7325
7326
7327
7328
7329
7330
7331
7332
7333
7334
7335
7336
7337
7338
7339
7340
7341
7342
7343
7344
7345
7346
7347
7348
7349
7350
7351
7352
7353
7354
7355
7356
7357
7358
7359
7360
7361
7362
7363
7364
7365
7366
7367
7368
7369
7370
7371
7372
7373
7374
7375
7376
7377
7378
7379
7380
7381
7382
7383
7384
7385
7386
7387
7388
7389
7390
7391
7392
7393
7394
7395
7396
7397
7398
7399
7400
7401
7402
7403
7404
7405
7406
7407
7408
7409
7410
7411
7412
7413
7414
7415
7416
7417
7418
7419
7420
7421
7422
7423
7424
7425
7426
7427
7428
7429
7430
7431
7432
7433
7434
7435
7436
7437
7438
7439
7440
7441
7442
7443
7444
7445
7446
7447
7448
7449
7450
7451
7452
7453
7454
7455
7456
7457
7458
7459
7460
7461
7462
7463
7464
7465
7466
7467
7468
7469
7470
7471
7472
7473
7474
7475
7476
7477
7478
7479
7480
7481
7482
7483
7484
7485
7486
7487
7488
7489
7490
7491
7492
7493
7494
7495
7496
7497
7498
7499
7500
7501
7502
7503
7504
7505
7506
7507
7508
7509
7510
7511
7512
7513
7514
7515
7516
7517
7518
7519
7520
7521
7522
7523
7524
7525
7526
7527
7528
7529
7530
7531
7532
7533
7534
7535
7536
7537
7538
7539
7540
7541
7542
7543
7544
7545
7546
7547
7548
7549
7550
7551
7552
7553
7554
7555
7556
7557
7558
7559
7560
7561
7562
7563
7564
7565
7566
7567
7568
7569
7570
7571
7572
7573
7574
7575
7576
7577
7578
7579
7580
7581
7582
7583
7584
7585
7586
7587
7588
7589
7590
7591
7592
7593
7594
7595
7596
7597
7598
7599
7600
7601
7602
7603
7604
7605
7606
7607
7608
7609
7610
7611
7612
7613
7614
7615
7616
7617
7618
7619
7620
7621
7622
7623
7624
7625
7626
7627
7628
7629
7630
7631
7632
7633
7634
7635
7636
7637
7638
7639
7640
7641
7642
7643
7644
7645
7646
7647
7648
7649
7650
7651
7652
7653
7654
7655
7656
7657
7658
7659
7660
7661
7662
7663
7664
7665
7666
7667
7668
7669
7670
7671
7672
7673
7674
7675
7676
7677
7678
7679
7680
7681
7682
7683
7684
7685
7686
7687
7688
7689
7690
7691
7692
7693
7694
7695
7696
7697
7698
7699
7700
7701
7702
7703
7704
7705
7706
7707
7708
7709
7710
7711
7712
7713
7714
7715
7716
7717
7718
7719
7720
7721
7722
7723
7724
7725
7726
7727
7728
7729
7730
7731
7732
7733
7734
7735
7736
7737
7738
7739
7740
7741
7742
7743
7744
7745
7746
7747
7748
7749
7750
7751
7752
7753
7754
7755
7756
7757
7758
7759
7760
7761
7762
7763
7764
7765
7766
7767
7768
7769
7770
7771
7772
7773
7774
7775
7776
7777
7778
7779
7780
7781
7782
7783
7784
7785
7786
7787
7788
7789
7790
7791
7792
7793
7794
7795
7796
7797
7798
7799
7800
7801
7802
7803
7804
7805
7806
7807
7808
7809
7810
7811
7812
7813
7814
7815
7816
7817
7818
7819
7820
7821
7822
7823
7824
7825
7826
7827
7828
7829
7830
7831
7832
7833
7834
7835
7836
7837
7838
7839
7840
7841
7842
7843
7844
7845
7846
7847
7848
7849
7850
7851
7852
7853
7854
7855
7856
7857
7858
7859
7860
7861
7862
7863
7864
7865
7866
7867
7868
7869
7870
7871
7872
7873
7874
7875
7876
7877
7878
7879
7880
7881
7882
7883
7884
7885
7886
7887
7888
7889
7890
7891
7892
7893
7894
7895
7896
7897
7898
7899
7900
7901
7902
7903
7904
7905
7906
7907
7908
7909
7910
7911
7912
7913
7914
7915
7916
7917
7918
7919
7920
7921
7922
7923
7924
7925
7926
7927
7928
7929
7930
7931
7932
7933
7934
7935
7936
7937
7938
7939
7940
7941
7942
7943
7944
7945
7946
7947
7948
7949
7950
7951
7952
7953
7954
7955
7956
7957
7958
7959
7960
7961
7962
7963
7964
7965
7966
7967
7968
7969
7970
7971
7972
7973
7974
7975
7976
7977
7978
7979
7980
7981
7982
7983
7984
7985
7986
7987
7988
7989
7990
7991
7992
7993
7994
7995
7996
7997
7998
7999
8000
8001
8002
8003
8004
8005
8006
8007
8008
8009
8010
8011
8012
8013
8014
8015
8016
8017
8018
8019
8020
8021
8022
8023
8024
8025
8026
8027
8028
8029
8030
8031
8032
8033
8034
8035
8036
8037
8038
8039
8040
8041
8042
8043
8044
8045
8046
8047
8048
8049
8050
8051
8052
8053
8054
8055
8056
8057
8058
8059
8060
8061
8062
8063
8064
8065
8066
8067
8068
8069
8070
8071
8072
8073
8074
8075
8076
8077
8078
8079
8080
8081
8082
8083
8084
8085
8086
8087
8088
8089
8090
8091
8092
8093
8094
8095
8096
8097
8098
8099
8100
8101
8102
8103
8104
8105
8106
8107
8108
8109
8110
8111
8112
8113
8114
8115
8116
8117
8118
8119
8120
8121
8122
8123
8124
8125
8126
8127
8128
8129
8130
8131
8132
8133
8134
8135
8136
8137
8138
8139
8140
8141
8142
8143
8144
8145
8146
8147
8148
8149
8150
8151
8152
8153
8154
8155
8156
8157
8158
8159
8160
8161
8162
8163
8164
8165
8166
8167
8168
8169
8170
8171
8172
8173
8174
8175
8176
8177
8178
8179
8180
8181
8182
8183
8184
8185
8186
8187
8188
8189
8190
8191
8192
8193
8194
8195
8196
8197
8198
8199
8200
8201
8202
8203
8204
8205
8206
8207
8208
8209
8210
8211
8212
8213
8214
8215
8216
8217
8218
8219
8220
8221
8222
8223
8224
8225
8226
8227
8228
8229
8230
8231
8232
8233
8234
8235
8236
8237
8238
8239
8240
8241
8242
8243
8244
8245
8246
8247
8248
8249
8250
8251
8252
8253
8254
8255
8256
8257
8258
8259
8260
8261
8262
8263
8264
8265
8266
8267
8268
8269
8270
8271
8272
8273
8274
8275
8276
8277
8278
8279
8280
8281
8282
8283
8284
8285
8286
8287
8288
8289
8290
8291
8292
8293
8294
8295
8296
8297
8298
8299
8300
8301
8302
8303
8304
8305
8306
8307
8308
8309
8310
8311
8312
8313
8314
8315
8316
8317
8318
8319
8320
8321
8322
8323
8324
8325
8326
8327
8328
8329
8330
8331
8332
8333
8334
8335
8336
8337
8338
8339
8340
8341
8342
8343
8344
8345
8346
8347
8348
8349
8350
8351
8352
8353
8354
8355
8356
8357
8358
8359
8360
8361
8362
8363
8364
8365
8366
8367
8368
8369
8370
8371
8372
8373
8374
8375
8376
8377
8378
8379
8380
8381
8382
8383
8384
8385
8386
8387
8388
8389
8390
8391
8392
8393
8394
8395
8396
8397
8398
8399
8400
8401
8402
8403
8404
8405
8406
8407
8408
8409
8410
8411
8412
8413
8414
8415
8416
8417
8418
8419
8420
8421
8422
8423
8424
8425
8426
8427
8428
8429
8430
8431
8432
8433
8434
8435
8436
8437
8438
8439
8440
8441
8442
8443
8444
8445
8446
8447
8448
8449
8450
8451
8452
8453
8454
8455
8456
8457
8458
8459
8460
8461
8462
8463
8464
8465
8466
8467
8468
8469
8470
8471
8472
8473
8474
8475
8476
8477
8478
8479
8480
8481
8482
8483
8484
8485
8486
8487
8488
8489
8490
8491
8492
8493
8494
8495
8496
8497
8498
8499
8500
8501
8502
8503
8504
8505
8506
8507
8508
8509
8510
8511
8512
8513
8514
8515
8516
8517
8518
8519
8520
8521
8522
8523
8524
8525
8526
8527
8528
8529
8530
8531
8532
8533
8534
8535
8536
8537
8538
8539
8540
8541
8542
8543
8544
8545
8546
8547
8548
8549
8550
8551
8552
8553
8554
8555
8556
8557
8558
8559
8560
8561
8562
8563
8564
8565
8566
8567
8568
8569
8570
8571
8572
8573
8574
8575
8576
8577
8578
8579
8580
8581
8582
8583
8584
8585
8586
8587
8588
8589
8590
8591
8592
8593
8594
8595
8596
8597
8598
8599
8600
8601
8602
8603
8604
8605
8606
8607
8608
8609
8610
8611
8612
8613
8614
8615
8616
8617
8618
8619
8620
8621
8622
8623
8624
8625
8626
8627
8628
8629
8630
8631
8632
8633
8634
8635
8636
8637
8638
8639
8640
8641
8642
8643
8644
8645
8646
8647
8648
8649
8650
8651
8652
8653
8654
8655
8656
8657
8658
8659
8660
8661
8662
8663
8664
8665
8666
8667
8668
8669
8670
8671
8672
8673
8674
8675
8676
8677
8678
8679
8680
8681
8682
8683
8684
8685
8686
8687
8688
8689
8690
8691
8692
8693
8694
8695
8696
8697
8698
8699
8700
8701
8702
8703
8704
8705
8706
8707
8708
8709
8710
8711
8712
8713
8714
8715
8716
8717
8718
8719
8720
8721
8722
8723
8724
8725
8726
8727
8728
8729
8730
8731
8732
8733
8734
8735
8736
8737
8738
8739
8740
8741
8742
8743
8744
8745
8746
8747
8748
8749
8750
8751
8752
8753
8754
8755
8756
8757
8758
8759
8760
8761
8762
8763
8764
8765
8766
8767
8768
8769
8770
8771
8772
8773
8774
8775
8776
8777
8778
8779
8780
8781
8782
8783
8784
8785
8786
8787
8788
8789
8790
8791
8792
8793
8794
8795
8796
8797
8798
8799
8800
8801
8802
8803
8804
8805
8806
8807
8808
8809
8810
8811
8812
8813
8814
8815
8816
8817
8818
8819
8820
8821
8822
8823
8824
8825
8826
8827
8828
8829
8830
8831
8832
8833
8834
8835
8836
8837
8838
8839
8840
8841
8842
8843
8844
8845
8846
8847
8848
8849
8850
8851
8852
8853
8854
8855
8856
8857
8858
8859
8860
8861
8862
8863
8864
8865
8866
8867
8868
8869
8870
8871
8872
8873
8874
8875
8876
8877
8878
8879
8880
8881
8882
8883
8884
8885
8886
8887
8888
8889
8890
8891
8892
8893
8894
8895
8896
8897
8898
8899
8900
8901
8902
8903
8904
8905
8906
8907
8908
8909
8910
8911
8912
8913
8914
8915
8916
8917
8918
8919
8920
8921
8922
8923
8924
8925
8926
8927
8928
8929
8930
8931
8932
8933
8934
8935
8936
8937
8938
8939
8940
8941
8942
8943
8944
8945
8946
8947
8948
8949
8950
8951
8952
8953
8954
8955
8956
8957
8958
8959
8960
8961
8962
8963
8964
8965
8966
8967
8968
8969
8970
8971
8972
8973
8974
8975
8976
8977
8978
8979
8980
8981
8982
8983
8984
8985
8986
8987
8988
8989
8990
8991
8992
8993
8994
8995
8996
8997
8998
8999
9000
9001
9002
9003
9004
9005
9006
9007
9008
9009
9010
9011
9012
9013
9014
9015
9016
9017
9018
9019
9020
9021
9022
9023
9024
9025
9026
9027
9028
9029
9030
9031
9032
9033
9034
9035
9036
9037
9038
9039
9040
9041
9042
9043
9044
9045
9046
9047
9048
9049
9050
9051
9052
9053
9054
9055
9056
9057
9058
9059
9060
9061
9062
9063
9064
9065
9066
9067
9068
9069
9070
9071
9072
9073
9074
9075
9076
9077
9078
9079
9080
9081
9082
9083
9084
9085
9086
9087
9088
9089
9090
9091
9092
9093
9094
9095
9096
9097
9098
9099
9100
9101
9102
9103
9104
9105
9106
9107
9108
9109
9110
9111
9112
9113
9114
9115
9116
9117
9118
9119
9120
9121
9122
9123
9124
9125
9126
9127
9128
9129
9130
9131
9132
9133
9134
9135
9136
9137
9138
9139
9140
9141
9142
9143
9144
9145
9146
9147
9148
9149
9150
9151
9152
9153
9154
9155
9156
9157
9158
9159
9160
9161
9162
9163
9164
9165
9166
9167
9168
9169
9170
9171
9172
9173
9174
9175
9176
9177
9178
9179
9180
9181
9182
9183
9184
9185
9186
9187
9188
9189
9190
9191
9192
9193
9194
9195
9196
9197
9198
9199
9200
9201
9202
9203
9204
9205
9206
9207
9208
9209
9210
9211
9212
9213
9214
9215
9216
9217
9218
9219
9220
9221
9222
9223
9224
9225
9226
9227
9228
9229
9230
9231
9232
9233
9234
9235
9236
9237
9238
9239
9240
9241
9242
9243
9244
9245
9246
9247
9248
9249
9250
9251
9252
9253
9254
9255
9256
9257
9258
9259
9260
9261
9262
9263
9264
9265
9266
9267
9268
9269
9270
9271
9272
9273
9274
9275
9276
9277
9278
9279
9280
9281
9282
9283
9284
9285
9286
9287
9288
9289
9290
9291
9292
9293
9294
9295
9296
9297
9298
9299
9300
9301
9302
9303
9304
9305
9306
9307
9308
9309
9310
9311
9312
9313
9314
9315
9316
9317
9318
9319
9320
9321
9322
9323
9324
9325
9326
9327
9328
9329
9330
9331
9332
9333
9334
9335
9336
9337
9338
9339
9340
9341
9342
9343
9344
9345
9346
9347
9348
9349
9350
9351
9352
9353
9354
9355
9356
9357
9358
9359
9360
9361
9362
9363
9364
9365
9366
9367
9368
9369
9370
9371
9372
9373
9374
9375
9376
9377
9378
9379
9380
9381
9382
9383
9384
9385
9386
9387
9388
9389
9390
9391
9392
9393
9394
9395
9396
9397
9398
9399
9400
9401
9402
9403
9404
9405
9406
9407
9408
9409
9410
9411
9412
9413
9414
9415
9416
9417
9418
9419
9420
9421
9422
9423
9424
9425
9426
9427
9428
9429
9430
9431
9432
9433
9434
9435
9436
9437
9438
9439
9440
9441
9442
9443
9444
9445
9446
9447
9448
9449
9450
9451
9452
9453
9454
9455
9456
9457
9458
9459
9460
9461
9462
9463
9464
9465
9466
9467
9468
9469
9470
9471
9472
9473
9474
9475
9476
9477
9478
9479
9480
9481
9482
9483
9484
9485
9486
9487
9488
9489
9490
9491
9492
9493
9494
9495
9496
9497
9498
9499
9500
9501
9502
9503
9504
9505
9506
9507
9508
9509
9510
9511
9512
9513
9514
9515
9516
9517
9518
9519
9520
9521
9522
9523
9524
9525
9526
9527
9528
9529
9530
9531
9532
9533
9534
9535
9536
9537
9538
9539
9540
9541
9542
9543
9544
9545
9546
9547
9548
9549
9550
9551
9552
9553
9554
9555
9556
9557
9558
9559
9560
9561
9562
9563
9564
9565
9566
9567
9568
9569
9570
9571
9572
9573
9574
9575
9576
9577
9578
9579
9580
9581
9582
9583
9584
9585
9586
9587
9588
9589
9590
9591
9592
9593
9594
9595
9596
9597
9598
9599
9600
9601
9602
9603
9604
9605
9606
9607
9608
9609
9610
9611
9612
9613
9614
9615
9616
9617
9618
9619
9620
9621
9622
9623
9624
9625
9626
9627
9628
9629
9630
9631
9632
9633
9634
9635
9636
9637
9638
9639
9640
9641
9642
9643
9644
9645
9646
9647
9648
9649
9650
9651
9652
9653
9654
9655
9656
9657
9658
9659
9660
9661
9662
9663
9664
9665
9666
9667
9668
9669
9670
9671
9672
9673
9674
9675
9676
9677
9678
9679
9680
9681
9682
9683
9684
9685
9686
9687
9688
9689
9690
9691
9692
9693
9694
9695
9696
9697
9698
9699
9700
9701
9702
9703
9704
9705
9706
9707
9708
9709
9710
9711
9712
9713
9714
9715
9716
9717
9718
9719
9720
9721
9722
9723
9724
9725
9726
9727
9728
9729
9730
9731
9732
9733
9734
9735
9736
9737
9738
9739
9740
9741
9742
9743
9744
9745
9746
9747
9748
9749
9750
9751
9752
9753
9754
9755
9756
9757
9758
9759
9760
9761
9762
9763
9764
9765
9766
9767
9768
9769
9770
9771
9772
9773
9774
9775
9776
9777
9778
9779
9780
9781
9782
9783
9784
9785
9786
9787
9788
9789
9790
9791
9792
9793
9794
9795
9796
9797
9798
9799
9800
9801
9802
9803
9804
9805
9806
9807
9808
9809
9810
9811
9812
9813
9814
9815
9816
9817
9818
9819
9820
9821
9822
9823
9824
9825
9826
9827
9828
9829
9830
9831
9832
9833
9834
9835
9836
9837
9838
9839
9840
9841
9842
9843
9844
9845
9846
9847
9848
9849
9850
9851
9852
9853
9854
9855
9856
9857
9858
9859
9860
9861
9862
9863
9864
9865
9866
9867
9868
9869
9870
9871
9872
9873
9874
9875
9876
9877
9878
9879
9880
9881
9882
9883
9884
9885
9886
9887
9888
9889
9890
9891
9892
9893
9894
9895
9896
9897
9898
9899
9900
9901
9902
9903
9904
9905
9906
9907
9908
9909
9910
9911
9912
9913
9914
9915
9916
9917
9918
9919
9920
9921
9922
9923
9924
9925
9926
9927
9928
9929
9930
9931
9932
9933
9934
9935
9936
9937
9938
9939
9940
9941
9942
9943
9944
9945
9946
9947
9948
9949
9950
9951
9952
9953
9954
9955
9956
9957
9958
9959
9960
9961
9962
9963
9964
9965
9966
9967
9968
9969
9970
9971
9972
9973
9974
9975
9976
9977
9978
9979
9980
9981
9982
9983
9984
9985
9986
9987
9988
9989
9990
9991
9992
9993
9994
9995
9996
9997
9998
9999
10000
10001
10002
10003
10004
10005
10006
10007
10008
10009
10010
10011
10012
10013
10014
10015
10016
10017
10018
10019
10020
10021
10022
10023
10024
10025
10026
10027
10028
10029
10030
10031
10032
10033
10034
10035
10036
10037
10038
10039
10040
10041
10042
10043
10044
10045
10046
10047
10048
10049
10050
10051
10052
10053
10054
10055
10056
10057
10058
10059
10060
10061
10062
10063
10064
10065
10066
10067
10068
10069
10070
10071
10072
10073
10074
10075
10076
10077
10078
10079
10080
10081
10082
10083
10084
10085
10086
10087
10088
10089
10090
10091
10092
10093
10094
10095
10096
10097
10098
10099
10100
10101
10102
10103
10104
10105
10106
10107
10108
10109
10110
10111
10112
10113
10114
10115
10116
10117
10118
10119
10120
10121
10122
10123
10124
10125
10126
10127
10128
10129
10130
10131
10132
10133
10134
10135
10136
10137
10138
10139
10140
10141
10142
10143
10144
10145
10146
10147
10148
10149
10150
10151
10152
10153
10154
10155
10156
10157
10158
10159
10160
10161
10162
10163
10164
10165
10166
10167
10168
10169
10170
10171
10172
10173
10174
10175
10176
10177
10178
10179
10180
10181
10182
10183
10184
10185
10186
10187
10188
10189
10190
10191
10192
10193
10194
10195
10196
10197
10198
10199
10200
10201
10202
10203
10204
10205
10206
10207
10208
10209
10210
10211
10212
10213
10214
10215
10216
10217
10218
10219
10220
10221
10222
10223
10224
10225
10226
10227
10228
10229
10230
10231
10232
10233
10234
10235
10236
10237
10238
10239
10240
10241
10242
10243
10244
10245
10246
10247
10248
10249
10250
10251
10252
10253
10254
10255
10256
10257
10258
10259
10260
10261
10262
10263
10264
10265
10266
10267
10268
10269
10270
10271
10272
10273
10274
10275
10276
10277
10278
10279
10280
10281
10282
10283
10284
10285
10286
10287
10288
10289
10290
10291
10292
10293
10294
10295
10296
10297
10298
10299
10300
10301
10302
10303
10304
10305
10306
10307
10308
10309
10310
10311
10312
10313
10314
10315
10316
10317
10318
10319
10320
10321
10322
10323
10324
10325
10326
10327
10328
10329
10330
10331
10332
10333
10334
10335
10336
10337
10338
10339
10340
10341
10342
10343
10344
10345
10346
10347
10348
10349
10350
10351
10352
10353
10354
10355
10356
10357
10358
10359
10360
10361
10362
10363
10364
10365
10366
10367
10368
10369
10370
10371
10372
10373
10374
10375
10376
10377
10378
10379
10380
10381
10382
10383
10384
10385
10386
10387
10388
10389
10390
10391
10392
10393
10394
10395
10396
10397
10398
10399
10400
10401
10402
10403
10404
10405
10406
10407
10408
10409
10410
10411
10412
10413
10414
10415
10416
10417
10418
10419
10420
10421
10422
10423
10424
10425
10426
10427
10428
10429
10430
10431
10432
10433
10434
10435
10436
10437
10438
10439
10440
10441
10442
10443
10444
10445
10446
10447
10448
10449
10450
10451
10452
10453
10454
10455
10456
10457
10458
10459
10460
10461
10462
10463
10464
10465
10466
10467
10468
10469
10470
10471
10472
10473
10474
10475
10476
10477
10478
10479
10480
10481
10482
10483
10484
10485
10486
10487
10488
10489
10490
10491
10492
10493
10494
10495
10496
10497
10498
10499
10500
10501
10502
10503
10504
10505
10506
10507
10508
10509
10510
10511
10512
10513
10514
10515
10516
10517
10518
10519
10520
10521
10522
10523
10524
10525
10526
10527
10528
10529
10530
10531
10532
10533
10534
10535
10536
10537
10538
10539
10540
10541
10542
10543
10544
10545
10546
10547
10548
10549
10550
10551
10552
10553
10554
10555
10556
10557
10558
10559
10560
10561
10562
10563
10564
10565
10566
10567
10568
10569
10570
10571
10572
10573
10574
10575
10576
10577
10578
10579
10580
10581
10582
10583
10584
10585
10586
10587
10588
10589
10590
10591
10592
10593
10594
10595
10596
10597
10598
10599
10600
10601
10602
10603
10604
10605
10606
10607
10608
10609
10610
10611
10612
10613
10614
10615
10616
10617
10618
10619
10620
10621
10622
10623
10624
10625
10626
10627
10628
10629
10630
10631
10632
10633
10634
10635
10636
10637
10638
10639
10640
10641
10642
10643
10644
10645
10646
10647
10648
10649
10650
10651
10652
10653
10654
10655
10656
10657
10658
10659
10660
10661
10662
10663
10664
10665
10666
10667
10668
10669
10670
10671
10672
10673
10674
10675
10676
10677
10678
10679
10680
10681
10682
10683
10684
10685
10686
10687
10688
10689
10690
10691
10692
10693
10694
10695
10696
10697
10698
10699
10700
10701
10702
10703
10704
10705
10706
10707
10708
10709
10710
10711
10712
10713
10714
10715
10716
10717
10718
10719
10720
10721
10722
10723
10724
10725
10726
10727
10728
10729
10730
10731
10732
10733
10734
10735
10736
10737
10738
10739
10740
10741
10742
10743
10744
10745
10746
10747
10748
10749
10750
10751
10752
10753
10754
10755
10756
10757
10758
10759
10760
10761
10762
10763
10764
10765
10766
10767
10768
10769
10770
10771
10772
10773
10774
10775
10776
10777
10778
10779
10780
10781
10782
10783
10784
10785
10786
10787
10788
10789
10790
10791
10792
10793
10794
10795
10796
10797
10798
10799
10800
10801
10802
10803
10804
10805
10806
10807
10808
10809
10810
10811
10812
10813
10814
10815
10816
10817
10818
10819
10820
10821
10822
10823
10824
10825
10826
10827
10828
10829
10830
10831
10832
10833
10834
10835
10836
10837
10838
10839
10840
10841
10842
10843
10844
10845
10846
10847
10848
10849
10850
10851
10852
10853
10854
10855
10856
10857
10858
10859
10860
10861
10862
10863
10864
10865
10866
10867
10868
10869
10870
10871
10872
10873
10874
10875
10876
10877
10878
10879
10880
10881
10882
10883
10884
10885
10886
10887
10888
10889
10890
10891
10892
10893
10894
10895
10896
10897
10898
10899
10900
10901
10902
10903
10904
10905
10906
10907
10908
10909
10910
10911
10912
10913
10914
10915
10916
10917
10918
10919
10920
10921
10922
10923
10924
10925
10926
10927
10928
10929
10930
10931
10932
10933
10934
10935
10936
10937
10938
10939
10940
10941
10942
10943
10944
10945
10946
10947
10948
10949
10950
10951
10952
10953
10954
10955
10956
10957
10958
10959
10960
10961
10962
10963
10964
10965
10966
10967
10968
10969
10970
10971
10972
10973
10974
10975
10976
10977
10978
10979
10980
10981
10982
10983
10984
10985
10986
10987
10988
10989
10990
10991
10992
10993
10994
10995
10996
10997
10998
10999
11000
11001
11002
11003
11004
11005
11006
11007
11008
11009
11010
11011
11012
11013
11014
11015
11016
11017
11018
11019
11020
11021
11022
11023
11024
11025
11026
11027
11028
11029
11030
11031
11032
11033
11034
11035
11036
11037
11038
11039
11040
11041
11042
11043
11044
11045
11046
11047
11048
11049
11050
11051
11052
11053
11054
11055
11056
11057
11058
11059
11060
11061
11062
11063
11064
11065
11066
11067
11068
11069
11070
11071
11072
11073
11074
11075
11076
11077
11078
11079
11080
11081
11082
11083
11084
11085
11086
11087
11088
11089
11090
11091
11092
11093
11094
11095
11096
11097
11098
11099
11100
11101
11102
11103
11104
11105
11106
11107
11108
11109
11110
11111
11112
11113
11114
11115
11116
11117
11118
11119
11120
11121
11122
11123
11124
11125
11126
11127
11128
11129
11130
11131
11132
11133
11134
11135
11136
11137
11138
11139
11140
11141
11142
11143
11144
11145
11146
11147
11148
11149
11150
11151
11152
11153
11154
11155
11156
11157
11158
11159
11160
11161
11162
11163
11164
11165
11166
11167
11168
11169
11170
11171
11172
11173
11174
11175
11176
11177
11178
11179
11180
11181
11182
11183
11184
11185
11186
11187
11188
11189
11190
11191
11192
11193
11194
11195
11196
11197
11198
11199
11200
11201
11202
11203
11204
11205
11206
11207
11208
11209
11210
11211
11212
11213
11214
11215
11216
11217
11218
11219
11220
11221
11222
11223
11224
11225
11226
11227
11228
11229
11230
11231
11232
11233
11234
11235
11236
11237
11238
11239
11240
11241
11242
11243
11244
11245
11246
11247
11248
11249
11250
11251
11252
11253
11254
11255
11256
11257
11258
11259
11260
11261
11262
11263
11264
11265
11266
11267
11268
11269
11270
11271
11272
11273
11274
11275
11276
11277
11278
11279
11280
11281
11282
11283
11284
11285
11286
11287
11288
11289
11290
11291
11292
11293
11294
11295
11296
11297
11298
11299
11300
11301
11302
11303
11304
11305
11306
11307
11308
11309
11310
11311
11312
11313
11314
11315
11316
11317
11318
11319
11320
11321
11322
11323
11324
11325
11326
11327
11328
11329
11330
11331
11332
11333
11334
11335
11336
11337
11338
11339
11340
11341
11342
11343
11344
11345
11346
11347
11348
11349
11350
11351
11352
11353
11354
11355
11356
11357
11358
11359
11360
11361
11362
11363
11364
11365
11366
11367
11368
11369
11370
11371
11372
11373
11374
11375
11376
11377
11378
11379
11380
11381
11382
11383
11384
11385
11386
11387
11388
11389
11390
11391
11392
11393
11394
11395
11396
11397
11398
11399
11400
11401
11402
11403
11404
11405
11406
11407
11408
11409
11410
11411
11412
11413
11414
11415
11416
11417
11418
11419
11420
11421
11422
11423
11424
11425
11426
11427
11428
11429
11430
11431
11432
11433
11434
11435
11436
11437
11438
11439
11440
11441
11442
11443
11444
11445
11446
11447
11448
11449
11450
11451
11452
11453
11454
11455
11456
11457
11458
11459
11460
11461
11462
11463
11464
11465
11466
11467
11468
11469
11470
11471
11472
11473
11474
11475
11476
11477
11478
11479
11480
11481
11482
11483
11484
11485
11486
11487
11488
11489
11490
11491
11492
11493
11494
11495
11496
11497
11498
11499
11500
11501
11502
11503
11504
11505
11506
11507
11508
11509
11510
11511
11512
11513
11514
11515
11516
11517
11518
11519
11520
11521
11522
11523
11524
11525
11526
11527
11528
11529
11530
11531
11532
11533
11534
11535
11536
11537
11538
11539
11540
11541
11542
11543
11544
11545
11546
11547
11548
11549
11550
11551
11552
11553
11554
11555
11556
11557
11558
11559
11560
11561
11562
11563
11564
11565
11566
11567
11568
11569
11570
11571
11572
11573
11574
11575
11576
11577
11578
11579
11580
11581
11582
11583
11584
11585
11586
11587
11588
11589
11590
11591
11592
11593
11594
11595
11596
11597
11598
11599
11600
11601
11602
11603
11604
11605
11606
11607
11608
11609
11610
11611
11612
11613
11614
11615
11616
11617
11618
11619
11620
11621
11622
11623
11624
11625
11626
11627
11628
11629
11630
11631
11632
11633
11634
11635
11636
11637
11638
11639
11640
11641
11642
11643
11644
11645
11646
11647
11648
11649
11650
11651
11652
11653
11654
11655
11656
11657
11658
11659
11660
11661
11662
11663
11664
11665
11666
11667
11668
11669
11670
11671
11672
11673
11674
11675
11676
11677
11678
11679
11680
11681
11682
11683
11684
11685
11686
11687
11688
11689
11690
11691
11692
11693
11694
11695
11696
11697
11698
11699
11700
11701
11702
11703
11704
11705
11706
11707
11708
11709
11710
11711
11712
11713
11714
11715
11716
11717
11718
11719
11720
11721
11722
11723
11724
11725
11726
11727
11728
11729
11730
11731
11732
11733
11734
11735
11736
11737
11738
11739
11740
11741
11742
11743
11744
11745
11746
11747
11748
11749
11750
11751
11752
11753
11754
11755
11756
11757
11758
11759
11760
11761
11762
11763
11764
11765
11766
11767
11768
11769
11770
11771
11772
11773
11774
11775
11776
11777
11778
11779
11780
11781
11782
11783
11784
11785
11786
11787
11788
11789
11790
11791
11792
11793
11794
11795
11796
11797
11798
11799
11800
11801
11802
11803
11804
11805
11806
11807
11808
11809
11810
11811
11812
11813
11814
11815
11816
11817
11818
11819
11820
11821
11822
11823
11824
11825
11826
11827
11828
11829
11830
11831
11832
11833
11834
11835
11836
11837
11838
11839
11840
11841
11842
11843
11844
11845
11846
11847
11848
11849
11850
11851
11852
11853
11854
11855
11856
11857
11858
11859
11860
11861
11862
11863
11864
11865
11866
11867
11868
11869
11870
11871
11872
11873
11874
11875
11876
11877
11878
11879
11880
11881
11882
11883
11884
11885
11886
11887
11888
11889
11890
11891
11892
11893
11894
11895
11896
11897
11898
11899
11900
11901
11902
11903
11904
11905
11906
11907
11908
11909
11910
11911
11912
11913
11914
11915
11916
11917
11918
11919
11920
11921
11922
11923
11924
11925
11926
11927
11928
11929
11930
11931
11932
11933
11934
11935
11936
11937
11938
11939
11940
11941
11942
11943
11944
11945
11946
11947
11948
11949
11950
11951
11952
11953
11954
11955
11956
11957
11958
11959
11960
11961
11962
11963
11964
11965
11966
11967
11968
11969
11970
11971
11972
11973
11974
11975
11976
11977
11978
11979
11980
11981
11982
11983
11984
11985
11986
11987
11988
11989
11990
11991
11992
11993
11994
11995
11996
11997
11998
11999
12000
12001
12002
12003
12004
12005
12006
12007
12008
12009
12010
12011
12012
12013
12014
12015
12016
12017
12018
12019
12020
12021
12022
12023
12024
12025
12026
12027
12028
12029
12030
12031
12032
12033
12034
12035
12036
12037
12038
12039
12040
12041
12042
12043
12044
12045
12046
12047
12048
12049
12050
12051
12052
12053
12054
12055
12056
12057
12058
12059
12060
12061
12062
12063
12064
12065
12066
12067
12068
12069
12070
12071
12072
12073
12074
12075
12076
12077
12078
12079
12080
12081
12082
12083
12084
12085
12086
12087
12088
12089
12090
12091
12092
12093
12094
12095
12096
12097
12098
12099
12100
12101
12102
12103
12104
12105
12106
12107
12108
12109
12110
12111
12112
12113
12114
12115
12116
12117
12118
12119
12120
12121
12122
12123
12124
12125
12126
12127
12128
12129
12130
12131
12132
12133
12134
12135
12136
12137
12138
12139
12140
12141
12142
12143
12144
12145
12146
12147
12148
12149
12150
12151
12152
12153
12154
12155
12156
12157
12158
12159
12160
12161
12162
12163
12164
12165
12166
12167
12168
12169
12170
12171
12172
12173
12174
12175
12176
12177
12178
12179
12180
12181
12182
12183
12184
12185
12186
12187
12188
12189
12190
12191
12192
12193
12194
12195
12196
12197
12198
12199
12200
12201
12202
12203
12204
12205
12206
12207
12208
12209
12210
12211
12212
12213
12214
12215
12216
12217
12218
12219
12220
12221
12222
12223
12224
12225
12226
12227
12228
12229
12230
12231
12232
12233
12234
12235
12236
12237
12238
12239
12240
12241
12242
12243
12244
12245
12246
12247
12248
12249
12250
12251
12252
12253
12254
12255
12256
12257
12258
12259
12260
12261
12262
12263
12264
12265
12266
12267
12268
12269
12270
12271
12272
12273
12274
12275
12276
12277
12278
12279
12280
12281
12282
12283
12284
12285
12286
12287
12288
12289
12290
12291
12292
12293
12294
12295
12296
12297
12298
12299
12300
12301
12302
12303
12304
12305
12306
12307
12308
12309
12310
12311
12312
12313
12314
12315
12316
12317
12318
12319
12320
12321
12322
12323
12324
12325
12326
12327
12328
12329
12330
12331
12332
12333
12334
12335
12336
12337
12338
12339
12340
12341
12342
12343
12344
12345
12346
12347
12348
12349
12350
12351
12352
12353
12354
12355
12356
12357
12358
12359
12360
12361
12362
12363
12364
12365
12366
12367
12368
12369
12370
12371
12372
12373
12374
12375
12376
12377
12378
12379
12380
12381
12382
12383
12384
12385
12386
12387
12388
12389
12390
12391
12392
12393
12394
12395
12396
12397
12398
12399
12400
12401
12402
12403
12404
12405
12406
12407
12408
12409
12410
12411
12412
12413
12414
12415
12416
12417
12418
12419
12420
12421
12422
12423
12424
12425
12426
12427
12428
12429
12430
12431
12432
12433
12434
12435
12436
12437
12438
12439
12440
12441
12442
12443
12444
12445
12446
12447
12448
12449
12450
12451
12452
12453
12454
12455
12456
12457
12458
12459
12460
12461
12462
12463
12464
12465
12466
12467
12468
12469
12470
12471
12472
12473
12474
12475
12476
12477
12478
12479
12480
12481
12482
12483
12484
12485
12486
12487
12488
12489
12490
12491
12492
12493
12494
12495
12496
12497
12498
12499
12500
12501
12502
12503
12504
12505
12506
12507
12508
12509
12510
12511
12512
12513
12514
12515
12516
12517
12518
12519
12520
12521
12522
12523
12524
12525
12526
12527
12528
12529
12530
12531
12532
12533
12534
12535
12536
12537
12538
12539
12540
12541
12542
12543
12544
12545
12546
12547
12548
12549
12550
12551
12552
12553
12554
12555
12556
12557
12558
12559
12560
12561
12562
12563
12564
12565
12566
12567
12568
12569
12570
12571
12572
12573
12574
12575
12576
12577
12578
12579
12580
12581
12582
12583
12584
12585
12586
12587
12588
12589
12590
12591
12592
12593
12594
12595
12596
12597
12598
12599
12600
12601
12602
12603
12604
12605
12606
12607
12608
12609
12610
12611
12612
12613
12614
12615
12616
12617
12618
12619
12620
12621
12622
12623
12624
12625
12626
12627
12628
12629
12630
12631
12632
12633
12634
12635
12636
12637
12638
12639
12640
12641
12642
12643
12644
12645
12646
12647
12648
12649
12650
12651
12652
12653
12654
12655
12656
12657
12658
12659
12660
12661
12662
12663
12664
12665
12666
12667
12668
12669
12670
12671
12672
12673
12674
12675
12676
12677
12678
12679
12680
12681
12682
12683
12684
12685
12686
12687
12688
12689
12690
12691
12692
12693
12694
12695
12696
12697
12698
12699
12700
12701
12702
12703
12704
12705
12706
12707
12708
12709
12710
12711
12712
12713
12714
12715
12716
12717
12718
12719
12720
12721
12722
12723
12724
12725
12726
12727
12728
12729
12730
12731
12732
12733
12734
12735
12736
12737
12738
12739
12740
12741
12742
12743
12744
12745
12746
12747
12748
12749
12750
12751
12752
12753
12754
12755
12756
12757
12758
12759
12760
12761
12762
12763
12764
12765
12766
12767
12768
12769
12770
12771
12772
12773
12774
12775
12776
12777
12778
12779
12780
12781
12782
12783
12784
12785
12786
12787
12788
12789
12790
12791
12792
12793
12794
12795
12796
12797
12798
12799
12800
12801
12802
12803
12804
12805
12806
12807
12808
12809
12810
12811
12812
12813
12814
12815
12816
12817
12818
12819
12820
12821
12822
12823
12824
12825
12826
12827
12828
12829
12830
12831
12832
12833
12834
12835
12836
12837
12838
12839
12840
12841
12842
12843
12844
12845
12846
12847
12848
12849
12850
12851
12852
12853
12854
12855
12856
12857
12858
12859
12860
12861
12862
12863
12864
12865
12866
12867
12868
12869
12870
12871
12872
12873
12874
12875
12876
12877
12878
12879
12880
12881
12882
12883
12884
12885
12886
12887
12888
12889
12890
12891
12892
12893
12894
12895
12896
12897
12898
12899
12900
12901
12902
12903
12904
12905
12906
12907
12908
12909
12910
12911
12912
12913
12914
12915
12916
12917
12918
12919
12920
12921
12922
12923
12924
12925
12926
12927
12928
12929
12930
12931
12932
12933
12934
12935
12936
12937
12938
12939
12940
12941
12942
12943
12944
12945
12946
12947
12948
12949
12950
12951
12952
12953
12954
12955
12956
12957
12958
12959
12960
12961
12962
12963
12964
12965
12966
12967
12968
12969
12970
12971
12972
12973
12974
12975
12976
12977
12978
12979
12980
12981
12982
12983
12984
12985
12986
12987
12988
12989
12990
12991
12992
12993
12994
12995
12996
12997
12998
12999
13000
13001
13002
13003
13004
13005
13006
13007
13008
13009
13010
13011
13012
13013
13014
13015
13016
13017
13018
13019
13020
13021
13022
13023
13024
13025
13026
13027
13028
13029
13030
13031
13032
13033
13034
13035
13036
13037
13038
13039
13040
13041
13042
13043
13044
13045
13046
13047
13048
13049
13050
13051
13052
13053
13054
13055
13056
13057
13058
13059
13060
13061
13062
13063
13064
13065
13066
13067
13068
13069
13070
13071
13072
13073
13074
13075
13076
13077
13078
13079
13080
13081
13082
13083
13084
13085
13086
13087
13088
13089
13090
13091
13092
13093
13094
13095
13096
13097
13098
13099
13100
13101
13102
13103
13104
13105
13106
13107
13108
13109
13110
13111
13112
13113
13114
13115
13116
13117
13118
13119
13120
13121
13122
13123
13124
13125
13126
13127
13128
13129
13130
13131
13132
13133
13134
13135
13136
13137
13138
13139
13140
13141
13142
13143
13144
13145
13146
13147
13148
13149
13150
13151
13152
13153
13154
13155
13156
13157
13158
13159
13160
13161
13162
13163
13164
13165
13166
13167
13168
13169
13170
13171
13172
13173
13174
13175
13176
13177
13178
13179
13180
13181
13182
13183
13184
13185
13186
13187
13188
13189
13190
13191
13192
13193
13194
13195
13196
13197
13198
13199
13200
13201
13202
13203
13204
13205
13206
13207
13208
13209
13210
13211
13212
13213
13214
13215
13216
13217
13218
13219
13220
13221
13222
13223
13224
13225
13226
13227
13228
13229
13230
13231
13232
13233
13234
13235
13236
13237
13238
13239
13240
13241
13242
13243
13244
13245
13246
13247
13248
13249
13250
13251
13252
13253
13254
13255
13256
13257
13258
13259
13260
13261
13262
13263
13264
13265
13266
13267
13268
13269
13270
13271
13272
13273
13274
13275
13276
13277
13278
13279
13280
13281
13282
13283
13284
13285
13286
13287
13288
13289
13290
13291
13292
13293
13294
13295
13296
13297
13298
13299
13300
13301
13302
13303
13304
13305
13306
13307
13308
13309
13310
13311
13312
13313
13314
13315
13316
13317
13318
13319
13320
13321
13322
13323
13324
13325
13326
13327
13328
13329
13330
13331
13332
13333
13334
13335
13336
13337
13338
13339
13340
13341
13342
13343
13344
13345
13346
13347
13348
13349
13350
13351
13352
13353
13354
13355
13356
13357
13358
13359
13360
13361
13362
13363
13364
13365
13366
13367
13368
13369
13370
13371
13372
13373
13374
13375
13376
13377
13378
13379
13380
13381
13382
13383
13384
13385
13386
13387
13388
13389
13390
13391
13392
13393
13394
13395
13396
13397
13398
13399
13400
13401
13402
13403
13404
13405
13406
13407
13408
13409
13410
13411
13412
13413
13414
13415
13416
13417
13418
13419
13420
13421
13422
13423
13424
13425
13426
13427
13428
13429
13430
13431
13432
13433
13434
13435
13436
13437
13438
13439
13440
13441
13442
13443
13444
13445
13446
13447
13448
13449
13450
13451
13452
13453
13454
13455
13456
13457
13458
13459
13460
13461
13462
13463
13464
13465
13466
13467
13468
13469
13470
13471
13472
13473
13474
13475
13476
13477
13478
13479
13480
13481
13482
13483
13484
13485
13486
13487
13488
13489
13490
13491
13492
13493
13494
13495
13496
13497
13498
13499
13500
13501
13502
13503
13504
13505
13506
13507
13508
13509
13510
13511
13512
13513
13514
13515
13516
13517
13518
13519
13520
13521
13522
13523
13524
13525
13526
13527
13528
13529
13530
13531
13532
13533
13534
13535
13536
13537
13538
13539
13540
13541
13542
13543
13544
13545
13546
13547
13548
13549
13550
13551
13552
13553
13554
13555
13556
13557
13558
13559
13560
13561
13562
13563
13564
13565
13566
13567
13568
13569
13570
13571
13572
13573
13574
13575
13576
13577
13578
13579
13580
13581
13582
13583
13584
13585
13586
13587
13588
13589
13590
13591
13592
13593
13594
13595
13596
13597
13598
13599
13600
13601
13602
13603
13604
13605
13606
13607
13608
13609
13610
13611
13612
13613
13614
13615
13616
13617
13618
13619
13620
13621
13622
13623
13624
13625
13626
13627
13628
13629
13630
13631
13632
13633
13634
13635
13636
13637
13638
13639
13640
13641
13642
13643
13644
13645
13646
13647
13648
13649
13650
13651
13652
13653
13654
13655
13656
13657
13658
13659
13660
13661
13662
13663
13664
13665
13666
13667
13668
13669
13670
13671
13672
13673
13674
13675
13676
13677
13678
13679
13680
13681
13682
13683
13684
13685
13686
13687
13688
13689
13690
13691
13692
13693
13694
13695
13696
13697
13698
13699
13700
13701
13702
13703
13704
13705
13706
13707
13708
13709
13710
13711
13712
13713
13714
13715
13716
13717
13718
13719
13720
13721
13722
13723
13724
13725
13726
13727
13728
13729
13730
13731
13732
13733
13734
13735
13736
13737
13738
13739
13740
13741
13742
13743
13744
13745
13746
13747
13748
13749
13750
13751
13752
13753
13754
13755
13756
13757
13758
13759
13760
13761
13762
13763
13764
13765
13766
13767
13768
13769
13770
13771
13772
13773
13774
13775
13776
13777
13778
13779
13780
13781
13782
13783
13784
13785
13786
13787
13788
13789
13790
13791
13792
13793
13794
13795
13796
13797
13798
13799
13800
13801
13802
13803
13804
13805
13806
13807
13808
13809
13810
13811
13812
13813
13814
13815
13816
13817
13818
13819
13820
13821
13822
13823
13824
13825
13826
13827
13828
13829
13830
13831
13832
13833
13834
13835
13836
13837
13838
13839
13840
13841
13842
13843
13844
13845
13846
13847
13848
13849
13850
13851
13852
13853
13854
13855
13856
13857
13858
13859
13860
13861
13862
13863
13864
13865
13866
13867
13868
13869
13870
13871
13872
13873
13874
13875
13876
13877
13878
13879
13880
13881
13882
13883
13884
13885
13886
13887
13888
13889
13890
13891
13892
13893
13894
13895
13896
13897
13898
13899
13900
13901
13902
13903
13904
13905
13906
13907
13908
13909
13910
13911
13912
13913
13914
13915
13916
13917
13918
13919
13920
13921
13922
13923
13924
13925
13926
13927
13928
13929
13930
13931
13932
13933
13934
13935
13936
13937
13938
13939
13940
13941
13942
13943
13944
13945
13946
13947
13948
13949
13950
13951
13952
13953
13954
13955
13956
13957
13958
13959
13960
13961
13962
13963
13964
13965
13966
13967
13968
13969
13970
13971
13972
13973
13974
13975
13976
13977
13978
13979
13980
13981
13982
13983
13984
13985
13986
13987
13988
13989
13990
13991
13992
13993
13994
13995
13996
13997
13998
13999
14000
14001
14002
14003
14004
14005
14006
14007
14008
14009
14010
14011
14012
14013
14014
14015
14016
14017
14018
14019
14020
14021
14022
14023
14024
14025
14026
14027
14028
14029
14030
14031
14032
14033
14034
14035
14036
14037
14038
14039
14040
14041
14042
14043
14044
14045
14046
14047
14048
14049
14050
14051
14052
14053
14054
14055
14056
14057
14058
14059
14060
14061
14062
14063
14064
14065
14066
14067
14068
14069
14070
14071
14072
14073
14074
14075
14076
14077
14078
14079
14080
14081
14082
14083
14084
14085
14086
14087
14088
14089
14090
14091
14092
14093
14094
14095
14096
14097
14098
14099
14100
14101
14102
14103
14104
14105
14106
14107
14108
14109
14110
14111
14112
14113
14114
14115
14116
14117
14118
14119
14120
14121
14122
14123
14124
14125
14126
14127
14128
14129
14130
14131
14132
14133
14134
14135
14136
14137
14138
14139
14140
14141
14142
14143
14144
14145
14146
14147
14148
14149
14150
14151
14152
14153
14154
14155
14156
14157
14158
14159
14160
14161
14162
14163
14164
14165
14166
14167
14168
14169
14170
14171
14172
14173
14174
14175
14176
14177
14178
14179
14180
14181
14182
14183
14184
14185
14186
14187
14188
14189
14190
14191
14192
14193
14194
14195
14196
14197
14198
14199
14200
14201
14202
14203
14204
14205
14206
14207
14208
14209
14210
14211
14212
14213
14214
14215
14216
14217
14218
14219
14220
14221
14222
14223
14224
14225
14226
14227
14228
14229
14230
14231
14232
14233
14234
14235
14236
14237
14238
14239
14240
14241
14242
14243
14244
14245
14246
14247
14248
14249
14250
14251
14252
14253
14254
14255
14256
14257
14258
14259
14260
14261
14262
14263
14264
14265
14266
14267
14268
14269
14270
14271
14272
14273
14274
14275
14276
14277
14278
14279
14280
14281
14282
14283
14284
14285
14286
14287
14288
14289
14290
14291
14292
14293
14294
14295
14296
14297
14298
14299
14300
14301
14302
14303
14304
14305
14306
14307
14308
14309
14310
14311
14312
14313
14314
14315
14316
14317
14318
14319
14320
14321
14322
14323
14324
14325
14326
14327
14328
14329
14330
14331
14332
14333
14334
14335
14336
14337
14338
14339
14340
14341
14342
14343
14344
14345
14346
14347
14348
14349
14350
14351
14352
14353
14354
14355
14356
14357
14358
14359
14360
14361
14362
14363
14364
14365
14366
14367
14368
14369
14370
14371
14372
14373
14374
14375
14376
14377
14378
14379
14380
14381
14382
14383
14384
14385
14386
14387
14388
14389
14390
14391
14392
14393
14394
14395
14396
14397
14398
14399
14400
14401
14402
14403
14404
14405
14406
14407
14408
14409
14410
14411
14412
14413
14414
14415
14416
14417
14418
14419
14420
14421
14422
14423
14424
14425
14426
14427
14428
14429
14430
14431
14432
14433
14434
14435
14436
14437
14438
14439
14440
14441
14442
14443
14444
14445
14446
14447
14448
14449
14450
14451
14452
14453
14454
14455
14456
14457
14458
14459
14460
14461
14462
14463
14464
14465
14466
14467
14468
14469
14470
14471
14472
14473
14474
14475
14476
14477
14478
14479
14480
14481
14482
14483
14484
14485
14486
14487
14488
14489
14490
14491
14492
14493
14494
14495
14496
14497
14498
14499
14500
14501
14502
14503
14504
14505
14506
14507
14508
14509
14510
14511
14512
14513
14514
14515
14516
14517
14518
14519
14520
14521
14522
14523
14524
14525
14526
14527
14528
14529
14530
14531
14532
14533
14534
14535
14536
14537
14538
14539
14540
14541
14542
14543
14544
14545
14546
14547
14548
14549
14550
14551
14552
14553
14554
14555
14556
14557
14558
14559
14560
14561
14562
14563
14564
14565
14566
14567
14568
14569
14570
14571
14572
14573
14574
14575
14576
14577
14578
14579
14580
14581
14582
14583
14584
14585
14586
14587
14588
14589
14590
14591
14592
14593
14594
14595
14596
14597
14598
14599
14600
14601
14602
14603
14604
14605
14606
14607
14608
14609
14610
14611
14612
14613
14614
14615
14616
14617
14618
14619
14620
14621
14622
14623
14624
14625
14626
14627
14628
14629
14630
14631
14632
14633
14634
14635
14636
14637
14638
14639
14640
14641
14642
14643
14644
14645
14646
14647
14648
14649
14650
14651
14652
14653
14654
14655
14656
14657
14658
14659
14660
14661
14662
14663
14664
14665
14666
14667
14668
14669
14670
14671
14672
14673
14674
14675
14676
14677
14678
14679
14680
14681
14682
14683
14684
14685
14686
14687
14688
14689
14690
14691
14692
14693
14694
14695
14696
14697
14698
14699
14700
14701
14702
14703
14704
14705
14706
14707
14708
14709
14710
14711
14712
14713
14714
14715
14716
14717
14718
14719
14720
14721
14722
14723
14724
14725
14726
14727
14728
14729
14730
14731
14732
14733
14734
14735
14736
14737
14738
14739
14740
14741
14742
14743
14744
14745
14746
14747
14748
14749
14750
14751
14752
14753
14754
14755
14756
14757
14758
14759
14760
14761
14762
14763
14764
14765
14766
14767
14768
14769
14770
14771
14772
14773
14774
14775
14776
14777
14778
14779
14780
14781
14782
14783
14784
14785
14786
14787
14788
14789
14790
14791
14792
14793
14794
14795
14796
14797
14798
14799
14800
14801
14802
14803
14804
14805
14806
14807
14808
14809
14810
14811
14812
14813
14814
14815
14816
14817
14818
14819
14820
14821
14822
14823
14824
14825
14826
14827
14828
14829
14830
14831
14832
14833
14834
14835
14836
14837
14838
14839
14840
14841
14842
14843
14844
14845
14846
14847
14848
14849
14850
14851
14852
14853
14854
14855
14856
14857
14858
14859
14860
14861
14862
14863
14864
14865
14866
14867
14868
14869
14870
14871
14872
14873
14874
14875
14876
14877
14878
14879
14880
14881
14882
14883
14884
14885
14886
14887
14888
14889
14890
14891
14892
14893
14894
14895
14896
14897
14898
14899
14900
14901
14902
14903
14904
14905
14906
14907
14908
14909
14910
14911
14912
14913
14914
14915
14916
14917
14918
14919
14920
14921
14922
14923
14924
14925
14926
14927
14928
14929
14930
14931
14932
14933
14934
14935
14936
14937
14938
14939
14940
14941
14942
14943
14944
14945
14946
14947
14948
14949
14950
14951
14952
14953
14954
14955
14956
14957
14958
14959
14960
14961
14962
14963
14964
14965
14966
14967
14968
14969
14970
14971
14972
14973
14974
14975
14976
14977
14978
14979
14980
14981
14982
14983
14984
14985
14986
14987
14988
14989
14990
14991
14992
14993
14994
14995
14996
14997
14998
14999
15000
15001
15002
15003
15004
15005
15006
15007
15008
15009
15010
15011
15012
15013
15014
15015
15016
15017
15018
15019
15020
15021
15022
15023
15024
15025
15026
15027
15028
15029
15030
15031
15032
15033
15034
15035
15036
15037
15038
15039
15040
15041
15042
15043
15044
15045
15046
15047
15048
15049
15050
15051
15052
15053
15054
15055
15056
15057
15058
15059
15060
15061
15062
15063
15064
15065
15066
15067
15068
15069
15070
15071
15072
15073
15074
15075
15076
15077
15078
15079
15080
15081
15082
15083
15084
15085
15086
15087
15088
15089
15090
15091
15092
15093
15094
15095
15096
15097
15098
15099
15100
15101
15102
15103
15104
15105
15106
15107
15108
15109
15110
15111
15112
15113
15114
15115
15116
15117
15118
15119
15120
15121
15122
15123
15124
15125
15126
15127
15128
15129
15130
15131
15132
15133
15134
15135
15136
15137
15138
15139
15140
15141
15142
15143
15144
15145
15146
15147
15148
15149
15150
15151
15152
15153
15154
15155
15156
15157
15158
15159
15160
15161
15162
15163
15164
15165
15166
15167
15168
15169
15170
15171
15172
15173
15174
15175
15176
15177
15178
15179
15180
15181
15182
15183
15184
15185
15186
15187
15188
15189
15190
15191
15192
15193
15194
15195
15196
15197
15198
15199
15200
15201
15202
15203
15204
15205
15206
15207
15208
15209
15210
15211
15212
15213
15214
15215
15216
15217
15218
15219
15220
15221
15222
15223
15224
15225
15226
15227
15228
15229
15230
15231
15232
15233
15234
15235
15236
15237
15238
15239
15240
15241
15242
15243
15244
15245
15246
15247
15248
15249
15250
15251
15252
15253
15254
15255
15256
15257
15258
15259
15260
15261
15262
15263
15264
15265
15266
15267
15268
15269
15270
15271
15272
15273
15274
15275
15276
15277
15278
15279
15280
15281
15282
15283
15284
15285
15286
15287
15288
15289
15290
15291
15292
15293
15294
15295
15296
15297
15298
15299
15300
15301
15302
15303
15304
15305
15306
15307
15308
15309
15310
15311
15312
15313
15314
15315
15316
15317
15318
15319
15320
15321
15322
15323
15324
15325
15326
15327
15328
15329
15330
15331
15332
15333
15334
15335
15336
15337
15338
15339
15340
15341
15342
15343
15344
15345
15346
15347
15348
15349
15350
15351
15352
15353
15354
15355
15356
15357
15358
15359
15360
15361
15362
15363
15364
15365
15366
15367
15368
15369
15370
15371
15372
15373
15374
15375
15376
15377
15378
15379
15380
15381
15382
15383
15384
15385
15386
15387
15388
15389
15390
15391
15392
15393
15394
15395
15396
15397
15398
15399
15400
15401
15402
15403
15404
15405
15406
15407
15408
15409
15410
15411
15412
15413
15414
15415
15416
15417
15418
15419
15420
15421
15422
15423
15424
15425
15426
15427
15428
15429
15430
15431
15432
15433
15434
15435
15436
15437
15438
15439
15440
15441
15442
15443
15444
15445
15446
15447
15448
15449
15450
15451
15452
15453
15454
15455
15456
15457
15458
15459
15460
15461
15462
15463
15464
15465
15466
15467
15468
15469
15470
15471
15472
15473
15474
15475
15476
15477
15478
15479
15480
15481
15482
15483
15484
15485
15486
15487
15488
15489
15490
15491
15492
15493
15494
15495
15496
15497
15498
15499
15500
15501
15502
15503
15504
15505
15506
15507
15508
15509
15510
15511
15512
15513
15514
15515
15516
15517
15518
15519
15520
15521
15522
15523
15524
15525
15526
15527
15528
15529
15530
15531
15532
15533
15534
15535
15536
15537
15538
15539
15540
15541
15542
15543
15544
15545
15546
15547
15548
15549
15550
15551
15552
15553
15554
15555
15556
15557
15558
15559
15560
15561
15562
15563
15564
15565
15566
15567
15568
15569
15570
15571
15572
15573
15574
15575
15576
15577
15578
15579
15580
15581
15582
15583
15584
15585
15586
15587
15588
15589
15590
15591
15592
15593
15594
15595
15596
15597
15598
15599
15600
15601
15602
15603
15604
15605
15606
15607
15608
15609
15610
15611
15612
15613
15614
15615
15616
15617
15618
15619
15620
15621
15622
15623
15624
15625
15626
15627
15628
15629
15630
15631
15632
15633
15634
15635
15636
15637
15638
15639
15640
15641
15642
15643
15644
15645
15646
15647
15648
15649
15650
15651
15652
15653
15654
15655
15656
15657
15658
15659
15660
15661
15662
15663
15664
15665
15666
15667
15668
15669
15670
15671
15672
15673
15674
15675
15676
15677
15678
15679
15680
15681
15682
15683
15684
15685
15686
15687
15688
15689
15690
15691
15692
15693
15694
15695
15696
15697
15698
15699
15700
15701
15702
15703
15704
15705
15706
15707
15708
15709
15710
15711
15712
15713
15714
15715
15716
15717
15718
15719
15720
15721
15722
15723
15724
15725
15726
15727
15728
15729
15730
15731
15732
15733
15734
15735
15736
15737
15738
15739
15740
15741
15742
15743
15744
15745
15746
15747
15748
15749
15750
15751
15752
15753
15754
15755
15756
15757
15758
15759
15760
15761
15762
15763
15764
15765
15766
15767
15768
15769
15770
15771
15772
15773
15774
15775
15776
15777
15778
15779
15780
15781
15782
15783
15784
15785
15786
15787
15788
15789
15790
15791
15792
15793
15794
15795
15796
15797
15798
15799
15800
15801
15802
15803
15804
15805
15806
15807
15808
15809
15810
15811
15812
15813
15814
15815
15816
15817
15818
15819
15820
15821
15822
15823
15824
15825
15826
15827
15828
15829
15830
15831
15832
15833
15834
15835
15836
15837
15838
15839
15840
15841
15842
15843
15844
15845
15846
15847
15848
15849
15850
15851
15852
15853
15854
15855
15856
15857
15858
15859
15860
15861
15862
15863
15864
15865
15866
15867
15868
15869
15870
15871
15872
15873
15874
15875
15876
15877
15878
15879
15880
15881
15882
15883
15884
15885
15886
15887
15888
15889
15890
15891
15892
15893
15894
15895
15896
15897
15898
15899
15900
15901
15902
15903
15904
15905
15906
15907
15908
15909
15910
15911
15912
15913
15914
15915
15916
15917
15918
15919
15920
15921
15922
15923
15924
15925
15926
15927
15928
15929
15930
15931
15932
15933
15934
15935
15936
15937
15938
15939
15940
15941
15942
15943
15944
15945
15946
15947
15948
15949
15950
15951
15952
15953
15954
15955
15956
15957
15958
15959
15960
15961
15962
15963
15964
15965
15966
15967
15968
15969
15970
15971
15972
15973
15974
15975
15976
15977
15978
15979
15980
15981
15982
15983
15984
15985
15986
15987
15988
15989
15990
15991
15992
15993
15994
15995
15996
15997
15998
15999
16000
16001
16002
16003
16004
16005
16006
16007
16008
16009
16010
16011
16012
16013
16014
16015
16016
16017
16018
16019
16020
16021
16022
16023
16024
16025
16026
16027
16028
16029
16030
16031
16032
16033
16034
16035
16036
16037
16038
16039
16040
16041
16042
16043
16044
16045
16046
16047
16048
16049
16050
16051
16052
16053
16054
16055
16056
16057
16058
16059
16060
16061
16062
16063
16064
16065
16066
16067
16068
16069
16070
16071
16072
16073
16074
16075
16076
16077
16078
16079
16080
16081
16082
16083
16084
16085
16086
16087
16088
16089
16090
16091
16092
16093
16094
16095
16096
16097
16098
16099
16100
16101
16102
16103
16104
16105
16106
16107
16108
16109
16110
16111
16112
16113
16114
16115
16116
16117
16118
16119
16120
16121
16122
16123
16124
16125
16126
16127
16128
16129
16130
16131
16132
16133
16134
16135
16136
16137
16138
16139
16140
16141
16142
16143
16144
16145
16146
16147
16148
16149
16150
16151
16152
16153
16154
16155
16156
16157
16158
16159
16160
16161
16162
16163
16164
16165
16166
16167
16168
16169
16170
16171
16172
16173
16174
16175
16176
16177
16178
16179
16180
16181
16182
16183
16184
16185
16186
16187
16188
16189
16190
16191
16192
16193
16194
16195
16196
16197
16198
16199
16200
16201
16202
16203
16204
16205
16206
16207
16208
16209
16210
16211
16212
16213
16214
16215
16216
16217
16218
16219
16220
16221
16222
16223
16224
16225
16226
16227
16228
16229
16230
16231
16232
16233
16234
16235
16236
16237
16238
16239
16240
16241
16242
16243
16244
16245
16246
16247
16248
16249
16250
16251
16252
16253
16254
16255
16256
16257
16258
16259
16260
16261
16262
16263
16264
16265
16266
16267
16268
16269
16270
16271
16272
16273
16274
16275
16276
16277
16278
16279
16280
16281
16282
16283
16284
16285
16286
16287
16288
16289
16290
16291
16292
16293
16294
16295
16296
16297
16298
16299
16300
16301
16302
16303
16304
16305
16306
16307
16308
16309
16310
16311
16312
16313
16314
16315
16316
16317
16318
16319
16320
16321
16322
16323
16324
16325
16326
16327
16328
16329
16330
16331
16332
16333
16334
16335
16336
16337
16338
16339
16340
16341
16342
16343
16344
16345
16346
16347
16348
16349
16350
16351
16352
16353
16354
16355
16356
16357
16358
16359
16360
16361
16362
16363
16364
16365
16366
16367
16368
16369
16370
16371
16372
16373
16374
16375
16376
16377
16378
16379
16380
16381
16382
16383
16384
16385
16386
16387
16388
16389
16390
16391
16392
16393
16394
16395
16396
16397
16398
16399
16400
16401
16402
16403
16404
16405
16406
16407
16408
16409
16410
16411
16412
16413
16414
16415
16416
16417
16418
16419
16420
16421
16422
16423
16424
16425
16426
16427
16428
16429
16430
16431
16432
16433
16434
16435
16436
16437
16438
16439
16440
16441
16442
16443
16444
16445
16446
16447
16448
16449
16450
16451
16452
16453
16454
16455
16456
16457
16458
16459
16460
16461
16462
16463
16464
16465
16466
16467
16468
16469
16470
16471
16472
16473
16474
16475
16476
16477
16478
16479
16480
16481
16482
16483
16484
16485
16486
16487
16488
16489
16490
16491
16492
16493
16494
16495
16496
16497
16498
16499
16500
16501
16502
16503
16504
16505
16506
16507
16508
16509
16510
16511
16512
16513
16514
16515
16516
16517
16518
16519
16520
16521
16522
16523
16524
16525
16526
16527
16528
16529
16530
16531
16532
16533
16534
16535
16536
16537
16538
16539
16540
16541
16542
16543
16544
16545
16546
16547
16548
16549
16550
16551
16552
16553
16554
16555
16556
16557
16558
16559
16560
16561
16562
16563
16564
16565
16566
16567
16568
16569
16570
16571
16572
16573
16574
16575
16576
16577
16578
16579
16580
16581
16582
16583
16584
16585
16586
16587
16588
16589
16590
16591
16592
16593
16594
16595
16596
16597
16598
16599
16600
16601
16602
16603
16604
16605
16606
16607
16608
16609
16610
16611
16612
16613
16614
16615
16616
16617
16618
16619
16620
16621
16622
16623
16624
16625
16626
16627
16628
16629
16630
16631
16632
16633
16634
16635
16636
16637
16638
16639
16640
16641
16642
16643
16644
16645
16646
16647
16648
16649
16650
16651
16652
16653
16654
16655
16656
16657
16658
16659
16660
16661
16662
16663
16664
16665
16666
16667
16668
16669
16670
16671
16672
16673
16674
16675
16676
16677
16678
16679
16680
16681
16682
16683
16684
16685
16686
16687
16688
16689
16690
16691
16692
16693
16694
16695
16696
16697
16698
16699
16700
16701
16702
16703
16704
16705
16706
16707
16708
16709
16710
16711
16712
16713
16714
16715
16716
16717
16718
16719
16720
16721
16722
16723
16724
16725
16726
16727
16728
16729
16730
16731
16732
16733
16734
16735
16736
16737
16738
16739
16740
16741
16742
16743
16744
16745
16746
16747
16748
16749
16750
16751
16752
16753
16754
16755
16756
16757
16758
16759
16760
16761
16762
16763
16764
16765
16766
16767
16768
16769
16770
16771
16772
16773
16774
16775
16776
16777
16778
16779
16780
16781
16782
16783
16784
16785
16786
16787
16788
16789
16790
16791
16792
16793
16794
16795
16796
16797
16798
16799
16800
16801
16802
16803
16804
16805
16806
16807
16808
16809
16810
16811
16812
16813
16814
16815
16816
16817
16818
16819
16820
16821
16822
16823
16824
16825
16826
16827
16828
16829
16830
16831
16832
16833
16834
16835
16836
16837
16838
16839
16840
16841
16842
16843
16844
16845
16846
16847
16848
16849
16850
16851
16852
16853
16854
16855
16856
16857
16858
16859
16860
16861
16862
16863
16864
16865
16866
16867
16868
16869
16870
16871
16872
16873
16874
16875
16876
16877
16878
16879
16880
16881
16882
16883
16884
16885
16886
16887
16888
16889
16890
16891
16892
16893
16894
16895
16896
16897
16898
16899
16900
16901
16902
16903
16904
16905
16906
16907
16908
16909
16910
16911
16912
16913
16914
16915
16916
16917
16918
16919
16920
16921
16922
16923
16924
16925
16926
16927
16928
16929
16930
16931
16932
16933
16934
16935
16936
16937
16938
16939
16940
16941
16942
16943
16944
16945
16946
16947
16948
16949
16950
16951
16952
16953
16954
16955
16956
16957
16958
16959
16960
16961
16962
16963
16964
16965
16966
16967
16968
16969
16970
16971
16972
16973
16974
16975
16976
16977
16978
16979
16980
16981
16982
16983
16984
16985
16986
16987
16988
16989
16990
16991
16992
16993
16994
16995
16996
16997
16998
16999
17000
17001
17002
17003
17004
17005
17006
17007
17008
17009
17010
17011
17012
17013
17014
17015
17016
17017
17018
17019
17020
17021
17022
17023
17024
17025
17026
17027
17028
17029
17030
17031
17032
17033
17034
17035
17036
17037
17038
17039
17040
17041
17042
17043
17044
17045
17046
17047
17048
17049
17050
17051
17052
17053
17054
17055
17056
17057
17058
17059
17060
17061
17062
17063
17064
17065
17066
17067
17068
17069
17070
17071
17072
17073
17074
17075
17076
17077
17078
17079
17080
17081
17082
17083
17084
17085
17086
17087
17088
17089
17090
17091
17092
17093
17094
17095
17096
17097
17098
17099
17100
17101
17102
17103
17104
17105
17106
17107
17108
17109
17110
17111
17112
17113
17114
17115
17116
17117
17118
17119
17120
17121
17122
17123
17124
17125
17126
17127
17128
17129
17130
17131
17132
17133
17134
17135
17136
17137
17138
17139
17140
17141
17142
17143
17144
17145
17146
17147
17148
17149
17150
17151
17152
17153
17154
17155
17156
17157
17158
17159
17160
17161
17162
17163
17164
17165
17166
17167
17168
17169
17170
17171
17172
17173
17174
17175
17176
17177
17178
17179
17180
17181
17182
17183
17184
17185
17186
17187
17188
17189
17190
17191
17192
17193
17194
17195
17196
17197
17198
17199
17200
17201
17202
17203
17204
17205
17206
17207
17208
17209
17210
17211
17212
17213
17214
17215
17216
17217
17218
17219
17220
17221
17222
17223
17224
17225
17226
17227
17228
17229
17230
17231
17232
17233
17234
17235
17236
17237
17238
17239
17240
17241
17242
17243
17244
17245
17246
17247
17248
17249
17250
17251
17252
17253
17254
17255
17256
17257
17258
17259
17260
17261
17262
17263
17264
17265
17266
17267
17268
17269
17270
17271
17272
17273
17274
17275
17276
17277
17278
17279
17280
17281
17282
17283
17284
17285
17286
17287
17288
17289
17290
17291
17292
17293
17294
17295
17296
17297
17298
17299
17300
17301
17302
17303
17304
17305
17306
17307
17308
17309
17310
17311
17312
17313
17314
17315
17316
17317
17318
17319
17320
17321
17322
17323
17324
17325
17326
17327
17328
17329
17330
17331
17332
17333
17334
17335
17336
17337
17338
17339
17340
17341
17342
17343
17344
17345
17346
17347
17348
17349
17350
17351
17352
17353
17354
17355
17356
17357
17358
17359
17360
17361
17362
17363
17364
17365
17366
17367
17368
17369
17370
17371
17372
17373
17374
17375
17376
17377
17378
17379
17380
17381
17382
17383
17384
17385
17386
17387
17388
17389
17390
17391
17392
17393
17394
17395
17396
17397
17398
17399
17400
17401
17402
17403
17404
17405
17406
17407
17408
17409
17410
17411
17412
17413
17414
17415
17416
17417
17418
17419
17420
17421
17422
17423
17424
17425
17426
17427
17428
17429
17430
17431
17432
17433
17434
17435
17436
17437
17438
17439
17440
17441
17442
17443
17444
17445
17446
17447
17448
17449
17450
17451
17452
17453
17454
17455
17456
17457
17458
17459
17460
17461
17462
17463
17464
17465
17466
17467
17468
17469
17470
17471
17472
17473
17474
17475
17476
17477
17478
17479
17480
17481
17482
17483
17484
17485
17486
17487
17488
17489
17490
17491
17492
17493
17494
17495
17496
17497
17498
17499
17500
17501
17502
17503
17504
17505
17506
17507
17508
17509
17510
17511
17512
17513
17514
17515
17516
17517
17518
17519
17520
17521
17522
17523
17524
17525
17526
17527
17528
17529
17530
17531
17532
17533
17534
17535
17536
17537
17538
17539
17540
17541
17542
17543
17544
17545
17546
17547
17548
17549
17550
17551
17552
17553
17554
17555
17556
17557
17558
17559
17560
17561
17562
17563
17564
17565
17566
17567
17568
17569
17570
17571
17572
17573
17574
17575
17576
17577
17578
17579
17580
17581
17582
17583
17584
17585
17586
17587
17588
17589
17590
17591
17592
17593
17594
17595
17596
17597
17598
17599
17600
17601
17602
17603
17604
17605
17606
17607
17608
17609
17610
17611
17612
17613
17614
17615
17616
17617
17618
17619
17620
17621
17622
17623
17624
17625
17626
17627
17628
17629
17630
17631
17632
17633
17634
17635
17636
17637
17638
17639
17640
17641
17642
17643
17644
17645
17646
17647
17648
17649
17650
17651
17652
17653
17654
17655
17656
17657
17658
17659
17660
17661
17662
17663
17664
17665
17666
17667
17668
17669
17670
17671
17672
17673
17674
17675
17676
17677
17678
17679
17680
17681
17682
17683
17684
17685
17686
17687
17688
17689
17690
17691
17692
17693
17694
17695
17696
17697
17698
17699
17700
17701
17702
17703
17704
17705
17706
17707
17708
17709
17710
17711
17712
17713
17714
17715
17716
17717
17718
17719
17720
17721
17722
17723
17724
17725
17726
17727
17728
17729
17730
17731
17732
17733
17734
17735
17736
17737
17738
17739
17740
17741
17742
17743
17744
17745
17746
17747
17748
17749
17750
17751
17752
17753
17754
17755
17756
17757
17758
17759
17760
17761
17762
17763
17764
17765
17766
17767
17768
17769
17770
17771
17772
17773
17774
17775
17776
17777
17778
17779
17780
17781
17782
17783
17784
17785
17786
17787
17788
17789
17790
17791
17792
17793
17794
17795
17796
17797
17798
17799
17800
17801
17802
17803
17804
17805
17806
17807
17808
17809
17810
17811
17812
17813
17814
17815
17816
17817
17818
17819
17820
17821
17822
17823
17824
17825
17826
17827
17828
17829
17830
17831
17832
17833
17834
17835
17836
17837
17838
17839
17840
17841
17842
17843
17844
17845
17846
17847
17848
17849
17850
17851
17852
17853
17854
17855
17856
17857
17858
17859
17860
17861
17862
17863
17864
17865
17866
17867
17868
17869
17870
17871
17872
17873
17874
17875
17876
17877
17878
17879
17880
17881
17882
17883
17884
17885
17886
17887
17888
17889
17890
17891
17892
17893
17894
17895
17896
17897
17898
17899
17900
17901
17902
17903
17904
17905
17906
17907
17908
17909
17910
17911
17912
17913
17914
17915
17916
17917
17918
17919
17920
17921
17922
17923
17924
17925
17926
17927
17928
17929
17930
17931
17932
17933
17934
17935
17936
17937
17938
17939
17940
17941
17942
17943
17944
17945
17946
17947
17948
17949
17950
17951
17952
17953
17954
17955
17956
17957
17958
17959
17960
17961
17962
17963
17964
17965
17966
17967
17968
17969
17970
17971
17972
17973
17974
17975
17976
17977
17978
17979
17980
17981
17982
17983
17984
17985
17986
17987
17988
17989
17990
17991
17992
17993
17994
17995
17996
17997
17998
17999
18000
18001
18002
18003
18004
18005
18006
18007
18008
18009
18010
18011
18012
18013
18014
18015
18016
18017
18018
18019
18020
18021
18022
18023
18024
18025
18026
18027
18028
18029
18030
18031
18032
18033
18034
18035
18036
18037
18038
18039
18040
18041
18042
18043
18044
18045
18046
18047
18048
18049
18050
18051
18052
18053
18054
18055
18056
18057
18058
18059
18060
18061
18062
18063
18064
18065
18066
18067
18068
18069
18070
18071
18072
18073
18074
18075
18076
18077
18078
18079
18080
18081
18082
18083
18084
18085
18086
18087
18088
18089
18090
18091
18092
18093
18094
18095
18096
18097
18098
18099
18100
18101
18102
18103
18104
18105
18106
18107
18108
18109
18110
18111
18112
18113
18114
18115
18116
18117
18118
18119
18120
18121
18122
18123
18124
18125
18126
18127
18128
18129
18130
18131
18132
18133
18134
18135
18136
18137
18138
18139
18140
18141
18142
18143
18144
18145
18146
18147
18148
18149
18150
18151
18152
18153
18154
18155
18156
18157
18158
18159
18160
18161
18162
18163
18164
18165
18166
18167
18168
18169
18170
18171
18172
18173
18174
18175
18176
18177
18178
18179
18180
18181
18182
18183
18184
18185
18186
18187
18188
18189
18190
18191
18192
18193
18194
18195
18196
18197
18198
18199
18200
18201
18202
18203
18204
18205
18206
18207
18208
18209
18210
18211
18212
18213
18214
18215
18216
18217
18218
18219
18220
18221
18222
18223
18224
18225
18226
18227
18228
18229
18230
18231
18232
18233
18234
18235
18236
18237
18238
18239
18240
18241
18242
18243
18244
18245
18246
18247
18248
18249
18250
18251
18252
18253
18254
18255
18256
18257
18258
18259
18260
18261
18262
18263
18264
18265
18266
18267
18268
18269
18270
18271
18272
18273
18274
18275
18276
18277
18278
18279
18280
18281
18282
18283
18284
18285
18286
18287
18288
18289
18290
18291
18292
18293
18294
18295
18296
18297
18298
18299
18300
18301
18302
18303
18304
18305
18306
18307
18308
18309
18310
18311
18312
18313
18314
18315
18316
18317
18318
18319
18320
18321
18322
18323
18324
18325
18326
18327
18328
18329
18330
18331
18332
18333
18334
18335
18336
18337
18338
18339
18340
18341
18342
18343
18344
18345
18346
18347
18348
18349
18350
18351
18352
18353
18354
18355
18356
18357
18358
18359
18360
18361
18362
18363
18364
18365
18366
18367
18368
18369
18370
18371
18372
18373
18374
18375
18376
18377
18378
18379
18380
18381
18382
18383
18384
18385
18386
18387
18388
18389
18390
18391
18392
18393
18394
18395
18396
18397
18398
18399
18400
18401
18402
18403
18404
18405
18406
18407
18408
18409
18410
18411
18412
18413
18414
18415
18416
18417
18418
18419
18420
18421
18422
18423
18424
18425
18426
18427
18428
18429
18430
18431
18432
18433
18434
18435
18436
18437
18438
18439
18440
18441
18442
18443
18444
18445
18446
18447
18448
18449
18450
18451
18452
18453
18454
18455
18456
18457
18458
18459
18460
18461
18462
18463
18464
18465
18466
18467
18468
18469
18470
18471
18472
18473
18474
18475
18476
18477
18478
18479
18480
18481
18482
18483
18484
18485
18486
18487
18488
18489
18490
18491
18492
18493
18494
18495
18496
18497
18498
18499
18500
18501
18502
18503
18504
18505
18506
18507
18508
18509
18510
18511
18512
18513
18514
18515
18516
18517
18518
18519
18520
18521
18522
18523
18524
18525
18526
18527
18528
18529
18530
18531
18532
18533
18534
18535
18536
18537
18538
18539
18540
18541
18542
18543
18544
18545
18546
18547
18548
18549
18550
18551
18552
18553
18554
18555
18556
18557
18558
18559
18560
18561
18562
18563
18564
18565
18566
18567
18568
18569
18570
18571
18572
18573
18574
18575
18576
18577
18578
18579
18580
18581
18582
18583
18584
18585
18586
18587
18588
18589
18590
18591
18592
18593
18594
18595
18596
18597
18598
18599
18600
18601
18602
18603
18604
18605
18606
18607
18608
18609
18610
18611
18612
18613
18614
18615
18616
18617
18618
18619
18620
18621
18622
18623
18624
18625
18626
18627
18628
18629
18630
18631
18632
18633
18634
18635
18636
18637
18638
18639
18640
18641
18642
18643
18644
18645
18646
18647
18648
18649
18650
18651
18652
18653
18654
18655
18656
18657
18658
18659
18660
18661
18662
18663
18664
18665
18666
18667
18668
18669
18670
18671
18672
18673
18674
18675
18676
18677
18678
18679
18680
18681
18682
18683
18684
18685
18686
18687
18688
18689
18690
18691
18692
18693
18694
18695
18696
18697
18698
18699
18700
18701
18702
18703
18704
18705
18706
18707
18708
18709
18710
18711
18712
18713
18714
18715
18716
18717
18718
18719
18720
18721
18722
18723
18724
18725
18726
18727
18728
18729
18730
18731
18732
18733
18734
18735
18736
18737
18738
18739
18740
18741
18742
18743
18744
18745
18746
18747
18748
18749
18750
18751
18752
18753
18754
18755
18756
18757
18758
18759
18760
18761
18762
18763
18764
18765
18766
18767
18768
18769
18770
18771
18772
18773
18774
18775
18776
18777
18778
18779
18780
18781
18782
18783
18784
18785
18786
18787
18788
18789
18790
18791
18792
18793
18794
18795
18796
18797
18798
18799
18800
18801
18802
18803
18804
18805
18806
18807
18808
18809
18810
18811
18812
18813
18814
18815
18816
18817
18818
18819
18820
18821
18822
18823
18824
18825
18826
18827
18828
18829
18830
18831
18832
18833
18834
18835
18836
18837
18838
18839
18840
18841
18842
18843
18844
18845
18846
18847
18848
18849
18850
18851
18852
18853
18854
18855
18856
18857
18858
18859
18860
18861
18862
18863
18864
18865
18866
18867
18868
18869
18870
18871
18872
18873
18874
18875
18876
18877
18878
18879
18880
18881
18882
18883
18884
18885
18886
18887
18888
18889
18890
18891
18892
18893
18894
18895
18896
18897
18898
18899
18900
18901
18902
18903
18904
18905
18906
18907
18908
18909
18910
18911
18912
18913
18914
18915
18916
18917
18918
18919
18920
18921
18922
18923
18924
18925
18926
18927
18928
18929
18930
18931
18932
18933
18934
18935
18936
18937
18938
18939
18940
18941
18942
18943
18944
18945
18946
18947
18948
18949
18950
18951
18952
18953
18954
18955
18956
18957
18958
18959
18960
18961
18962
18963
18964
18965
18966
18967
18968
18969
18970
18971
18972
18973
18974
18975
18976
18977
18978
18979
18980
18981
18982
18983
18984
18985
18986
18987
18988
18989
18990
18991
18992
18993
18994
18995
18996
18997
18998
18999
19000
19001
19002
19003
19004
19005
19006
19007
19008
19009
19010
19011
19012
19013
19014
19015
19016
19017
19018
19019
19020
19021
19022
19023
19024
19025
19026
19027
19028
19029
19030
19031
19032
19033
19034
19035
19036
19037
19038
19039
19040
19041
19042
19043
19044
19045
19046
19047
19048
19049
19050
19051
19052
19053
19054
19055
19056
19057
19058
19059
19060
19061
19062
19063
19064
19065
19066
19067
19068
19069
19070
19071
19072
19073
19074
19075
19076
19077
19078
19079
19080
19081
19082
19083
19084
19085
19086
19087
19088
19089
19090
19091
19092
19093
19094
19095
19096
19097
19098
19099
19100
19101
19102
19103
19104
19105
19106
19107
19108
19109
19110
19111
19112
19113
19114
19115
19116
19117
19118
19119
19120
19121
19122
19123
19124
19125
19126
19127
19128
19129
19130
19131
19132
19133
19134
19135
19136
19137
19138
19139
19140
19141
19142
19143
19144
19145
19146
19147
19148
19149
19150
19151
19152
19153
19154
19155
19156
19157
19158
19159
19160
19161
19162
19163
19164
19165
19166
19167
19168
19169
19170
19171
19172
19173
19174
19175
19176
19177
19178
19179
19180
19181
19182
19183
19184
19185
19186
19187
19188
19189
19190
19191
19192
19193
19194
19195
19196
19197
19198
19199
19200
19201
19202
19203
19204
19205
19206
19207
19208
19209
19210
19211
19212
19213
19214
19215
19216
19217
19218
19219
19220
19221
19222
19223
19224
19225
19226
19227
19228
19229
19230
19231
19232
19233
19234
19235
19236
19237
19238
19239
19240
19241
19242
19243
19244
19245
19246
19247
19248
19249
19250
19251
19252
19253
19254
19255
19256
19257
19258
19259
19260
19261
19262
19263
19264
19265
19266
19267
19268
19269
19270
19271
19272
19273
19274
19275
19276
19277
19278
19279
19280
19281
19282
19283
19284
19285
19286
19287
19288
19289
19290
19291
19292
19293
19294
19295
19296
19297
19298
19299
19300
19301
19302
19303
19304
19305
19306
19307
19308
19309
19310
19311
19312
19313
19314
19315
19316
19317
19318
19319
19320
19321
19322
19323
19324
19325
19326
19327
19328
19329
19330
19331
19332
19333
19334
19335
19336
19337
19338
19339
19340
19341
19342
19343
19344
19345
19346
19347
19348
19349
19350
19351
19352
19353
19354
19355
19356
19357
19358
19359
19360
19361
19362
19363
19364
19365
19366
19367
19368
19369
19370
19371
19372
19373
19374
19375
19376
19377
19378
19379
19380
19381
19382
19383
19384
19385
19386
19387
19388
19389
19390
19391
19392
19393
19394
19395
19396
19397
19398
19399
19400
19401
19402
19403
19404
19405
19406
19407
19408
19409
19410
19411
19412
19413
19414
19415
19416
19417
19418
19419
19420
19421
19422
19423
19424
19425
19426
19427
19428
19429
19430
19431
19432
19433
19434
19435
19436
19437
19438
19439
19440
19441
19442
19443
19444
19445
19446
19447
19448
19449
19450
19451
19452
19453
19454
19455
19456
19457
19458
19459
19460
19461
19462
19463
19464
19465
19466
19467
19468
19469
19470
19471
19472
19473
19474
19475
19476
19477
19478
19479
19480
19481
19482
19483
19484
19485
19486
19487
19488
19489
19490
19491
19492
19493
19494
19495
19496
19497
19498
19499
19500
19501
19502
19503
19504
19505
19506
19507
19508
19509
19510
19511
19512
19513
19514
19515
19516
19517
19518
19519
19520
19521
19522
19523
19524
19525
19526
19527
19528
19529
19530
19531
19532
19533
19534
19535
19536
19537
19538
19539
19540
19541
19542
19543
19544
19545
19546
19547
19548
19549
19550
19551
19552
19553
19554
19555
19556
19557
19558
19559
19560
19561
19562
19563
19564
19565
19566
19567
19568
19569
19570
19571
19572
19573
19574
19575
19576
19577
19578
19579
19580
19581
19582
19583
19584
19585
19586
19587
19588
19589
19590
19591
19592
19593
19594
19595
19596
19597
19598
19599
19600
19601
19602
19603
19604
19605
19606
19607
19608
19609
19610
19611
19612
19613
19614
19615
19616
19617
19618
19619
19620
19621
19622
19623
19624
19625
19626
19627
19628
19629
19630
19631
19632
19633
19634
19635
19636
19637
19638
19639
19640
19641
19642
19643
19644
19645
19646
19647
19648
19649
19650
19651
19652
19653
19654
19655
19656
19657
19658
19659
19660
19661
19662
19663
19664
19665
19666
19667
19668
19669
19670
19671
19672
19673
19674
19675
19676
19677
19678
19679
19680
19681
19682
19683
19684
19685
19686
19687
19688
19689
19690
19691
19692
19693
19694
19695
19696
19697
19698
19699
19700
19701
19702
19703
19704
19705
19706
19707
19708
19709
19710
19711
19712
19713
19714
19715
19716
19717
19718
19719
19720
19721
19722
19723
19724
19725
19726
19727
19728
19729
19730
19731
19732
19733
19734
19735
19736
19737
19738
19739
19740
19741
19742
19743
19744
19745
19746
19747
19748
19749
19750
19751
19752
19753
19754
19755
19756
19757
19758
19759
19760
19761
19762
19763
19764
19765
19766
19767
19768
19769
19770
19771
19772
19773
19774
19775
19776
19777
19778
19779
19780
19781
19782
19783
19784
19785
19786
19787
19788
19789
19790
19791
19792
19793
19794
19795
19796
19797
19798
19799
19800
19801
19802
19803
19804
19805
19806
19807
19808
19809
19810
19811
19812
19813
19814
19815
19816
19817
19818
19819
19820
19821
19822
19823
19824
19825
19826
19827
19828
19829
19830
19831
19832
19833
19834
19835
19836
19837
19838
19839
19840
19841
19842
19843
19844
19845
19846
19847
19848
19849
19850
19851
19852
19853
19854
19855
19856
19857
19858
19859
19860
19861
19862
19863
19864
19865
19866
19867
19868
19869
19870
19871
19872
19873
19874
19875
19876
19877
19878
19879
19880
19881
19882
19883
19884
19885
19886
19887
19888
19889
19890
19891
19892
19893
19894
19895
19896
19897
19898
19899
19900
19901
19902
19903
19904
19905
19906
19907
19908
19909
19910
19911
19912
19913
19914
19915
19916
19917
19918
19919
19920
19921
19922
19923
19924
19925
19926
19927
19928
19929
19930
19931
19932
19933
19934
19935
19936
19937
19938
19939
19940
19941
19942
19943
19944
19945
19946
19947
19948
19949
19950
19951
19952
19953
19954
19955
19956
19957
19958
19959
19960
19961
19962
19963
19964
19965
19966
19967
19968
19969
19970
19971
19972
19973
19974
19975
19976
19977
19978
19979
19980
19981
19982
19983
19984
19985
19986
19987
19988
19989
19990
19991
19992
19993
19994
19995
19996
19997
19998
19999
20000
20001
20002
20003
20004
20005
20006
20007
20008
20009
20010
20011
20012
20013
20014
20015
20016
20017
20018
20019
20020
20021
20022
20023
20024
20025
20026
20027
20028
20029
20030
20031
20032
20033
20034
20035
20036
20037
20038
20039
20040
20041
20042
20043
20044
20045
20046
20047
20048
20049
20050
20051
20052
20053
20054
20055
20056
20057
20058
20059
20060
20061
20062
20063
20064
20065
20066
20067
20068
20069
20070
20071
20072
20073
20074
20075
20076
20077
20078
20079
20080
20081
20082
20083
20084
20085
20086
20087
20088
20089
20090
20091
20092
20093
20094
20095
20096
20097
20098
20099
20100
20101
20102
20103
20104
20105
20106
20107
20108
20109
20110
20111
20112
20113
20114
20115
20116
20117
20118
20119
20120
20121
20122
20123
20124
20125
20126
20127
20128
20129
20130
20131
20132
20133
20134
20135
20136
20137
20138
20139
20140
20141
20142
20143
20144
20145
20146
20147
20148
20149
20150
20151
20152
20153
20154
20155
20156
20157
20158
20159
20160
20161
20162
20163
20164
20165
20166
20167
20168
20169
20170
20171
20172
20173
20174
20175
20176
20177
20178
20179
20180
20181
20182
20183
20184
20185
20186
20187
20188
20189
20190
20191
20192
20193
20194
20195
20196
20197
20198
20199
20200
20201
20202
20203
20204
20205
20206
20207
20208
20209
20210
20211
20212
20213
20214
20215
20216
20217
20218
20219
20220
20221
20222
20223
20224
20225
20226
20227
20228
20229
20230
20231
20232
20233
20234
20235
20236
20237
20238
20239
20240
20241
20242
20243
20244
20245
20246
20247
20248
20249
20250
20251
20252
20253
20254
20255
20256
20257
20258
20259
20260
20261
20262
20263
20264
20265
20266
20267
20268
20269
20270
20271
20272
20273
20274
20275
20276
20277
20278
20279
20280
20281
20282
20283
20284
20285
20286
20287
20288
20289
20290
20291
20292
20293
20294
20295
20296
20297
20298
20299
20300
20301
20302
20303
20304
20305
20306
20307
20308
20309
20310
20311
20312
20313
20314
20315
20316
20317
20318
20319
20320
20321
20322
20323
20324
20325
20326
20327
20328
20329
20330
20331
20332
20333
20334
20335
20336
20337
20338
20339
20340
20341
20342
20343
20344
20345
20346
20347
20348
20349
20350
20351
20352
20353
20354
20355
20356
20357
20358
20359
20360
20361
20362
20363
20364
20365
20366
20367
20368
20369
20370
20371
20372
20373
20374
20375
20376
20377
20378
20379
20380
20381
20382
20383
20384
20385
20386
20387
20388
20389
20390
20391
20392
20393
20394
20395
20396
20397
20398
20399
20400
20401
20402
20403
20404
20405
20406
20407
20408
20409
20410
20411
20412
20413
20414
20415
20416
20417
20418
20419
20420
20421
20422
20423
20424
20425
20426
20427
20428
20429
20430
20431
20432
20433
20434
20435
20436
20437
20438
20439
20440
20441
20442
20443
20444
20445
20446
20447
20448
20449
20450
20451
20452
20453
20454
20455
20456
20457
20458
20459
20460
20461
20462
20463
20464
20465
20466
20467
20468
20469
20470
20471
20472
20473
20474
20475
20476
20477
20478
20479
20480
20481
20482
20483
20484
20485
20486
20487
20488
20489
20490
20491
20492
20493
20494
20495
20496
20497
20498
20499
20500
20501
20502
20503
20504
20505
20506
20507
20508
20509
20510
20511
20512
20513
20514
20515
20516
20517
20518
20519
20520
20521
20522
20523
20524
20525
20526
20527
20528
20529
20530
20531
20532
20533
20534
20535
20536
20537
20538
20539
20540
20541
20542
20543
20544
20545
20546
20547
20548
20549
20550
20551
20552
20553
20554
20555
20556
20557
20558
20559
20560
20561
20562
20563
20564
20565
20566
20567
20568
20569
20570
20571
20572
20573
20574
20575
20576
20577
20578
20579
20580
20581
20582
20583
20584
20585
20586
20587
20588
20589
20590
20591
20592
20593
20594
20595
20596
20597
20598
20599
20600
20601
20602
20603
20604
20605
20606
20607
20608
20609
20610
20611
20612
20613
20614
20615
20616
20617
20618
20619
20620
20621
20622
20623
20624
20625
20626
20627
20628
20629
20630
20631
20632
20633
20634
20635
20636
20637
20638
20639
20640
20641
20642
20643
20644
20645
20646
20647
20648
20649
20650
20651
20652
20653
20654
20655
20656
20657
20658
20659
20660
20661
20662
20663
20664
20665
20666
20667
20668
20669
20670
20671
20672
20673
20674
20675
20676
20677
20678
20679
20680
20681
20682
20683
20684
20685
20686
20687
20688
20689
20690
20691
20692
20693
20694
20695
20696
20697
20698
20699
20700
20701
20702
20703
20704
20705
20706
20707
20708
20709
20710
20711
20712
20713
20714
20715
20716
20717
20718
20719
20720
20721
20722
20723
20724
20725
20726
20727
20728
20729
20730
20731
20732
20733
20734
20735
20736
20737
20738
20739
20740
20741
20742
20743
20744
20745
20746
20747
20748
20749
20750
20751
20752
20753
20754
20755
20756
20757
20758
20759
20760
20761
20762
20763
20764
20765
20766
20767
20768
20769
20770
20771
20772
20773
20774
20775
20776
20777
20778
20779
20780
20781
20782
20783
20784
20785
20786
20787
20788
20789
20790
20791
20792
20793
20794
20795
20796
20797
20798
20799
20800
20801
20802
20803
20804
20805
20806
20807
20808
20809
20810
20811
20812
20813
20814
20815
20816
20817
20818
20819
20820
20821
20822
20823
20824
20825
20826
20827
20828
20829
20830
20831
20832
20833
20834
20835
20836
20837
20838
20839
20840
20841
20842
20843
20844
20845
20846
20847
20848
20849
20850
20851
20852
20853
20854
20855
20856
20857
20858
20859
20860
20861
20862
20863
20864
20865
20866
20867
20868
20869
20870
20871
20872
20873
20874
20875
20876
20877
20878
20879
20880
20881
20882
20883
20884
20885
20886
20887
20888
20889
20890
20891
20892
20893
20894
20895
20896
20897
20898
20899
20900
20901
20902
20903
20904
20905
20906
20907
20908
20909
20910
20911
20912
20913
20914
20915
20916
20917
20918
20919
20920
20921
20922
20923
20924
20925
20926
20927
20928
20929
20930
20931
20932
20933
20934
20935
20936
20937
20938
20939
20940
20941
20942
20943
20944
20945
20946
20947
20948
20949
20950
20951
20952
20953
20954
20955
20956
20957
20958
20959
20960
20961
20962
20963
20964
20965
20966
20967
20968
20969
20970
20971
20972
20973
20974
20975
20976
20977
20978
20979
20980
20981
20982
20983
20984
20985
20986
20987
20988
20989
20990
20991
20992
20993
20994
20995
20996
20997
20998
20999
21000
21001
21002
21003
21004
21005
21006
21007
21008
21009
21010
21011
21012
21013
21014
21015
21016
21017
21018
21019
21020
21021
21022
21023
21024
21025
21026
21027
21028
21029
21030
21031
21032
21033
21034
21035
21036
21037
21038
21039
21040
21041
21042
21043
21044
21045
21046
21047
21048
21049
21050
21051
21052
21053
21054
21055
21056
21057
21058
21059
21060
21061
21062
21063
21064
21065
21066
21067
21068
21069
21070
21071
21072
21073
21074
21075
21076
21077
21078
21079
21080
21081
;;; GNU Guix --- Functional package management for GNU
;;; Copyright © 2015, 2016, 2017, 2018, 2019, 2020 Ricardo Wurmus <rekado@elephly.net>
;;; Copyright © 2015 Andreas Enge <andreas@enge.fr>
;;; Copyright © 2016, 2017 Ben Woodcroft <donttrustben@gmail.com>
;;; Copyright © 2016, 2017, 2018 Roel Janssen <roel@gnu.org>
;;; Copyright © 2017, 2018, 2019, 2020 Tobias Geerinckx-Rice <me@tobias.gr>
;;; Copyright © 2017 Raoul Bonnal <ilpuccio.febo@gmail.com>
;;; Copyright © 2018 Vijayalakshmi Vedantham <vijimay12@gmail.com>
;;; Copyright © 2018 Sahithi Yarlagadda <sahi@swecha.net>
;;; Copyright © 2018 Sandeep Subramanian <sandeepsubramanian94@gmail.com>
;;; Copyright © 2018 Charlie Ritter <chewzeirta@posteo.net>
;;; Copyright © 2018 Konrad Hinsen <konrad.hinsen@fastmail.net>
;;; Copyright © 2018, 2020 Mădălin Ionel Patrașcu <madalinionel.patrascu@mdc-berlin.de>
;;; Copyright © 2018 Laura Lazzati <laura.lazzati.15@gmail.com>
;;; Copyright © 2018 Leo Famulari <leo@famulari.name>
;;; Copyright © 2018 Marius Bakke <mbakke@fastmail.com>
;;; Copyright © 2018 Eric Brown <brown@fastmail.com>
;;; Copyright © 2018, 2019 Brett Gilio <brettg@gnu.org>
;;; Copyright © 2019 Nicolò Balzarotti <anothersms@gmail.com>
;;; Copyright © 2019 Wiktor Żelazny <wzelazny@vurv.cz>
;;; Copyright © 2020 Todor Kondić <tk.code@protonmail.com>
;;; Copyright © 2020 Danjela Lura <danielaluraa@gmail.com>
;;; Copyright © 2020 Naga Malleswari <nagamalli@riseup.net>
;;;
;;; This file is part of GNU Guix.
;;;
;;; GNU Guix is free software; you can redistribute it and/or modify it
;;; under the terms of the GNU General Public License as published by
;;; the Free Software Foundation; either version 3 of the License, or (at
;;; your option) any later version.
;;;
;;; GNU Guix is distributed in the hope that it will be useful, but
;;; WITHOUT ANY WARRANTY; without even the implied warranty of
;;; MERCHANTABILITY or FITNESS FOR A PARTICULAR PURPOSE.  See the
;;; GNU General Public License for more details.
;;;
;;; You should have received a copy of the GNU General Public License
;;; along with GNU Guix.  If not, see <http://www.gnu.org/licenses/>.

(define-module (gnu packages cran)
  #:use-module ((guix licenses) #:prefix license:)
  #:use-module (guix packages)
  #:use-module (guix download)
  #:use-module (guix git-download)
  #:use-module (guix utils)
  #:use-module (guix build-system r)
  #:use-module (gnu packages algebra)
  #:use-module (gnu packages autotools)
  #:use-module (gnu packages base)
  #:use-module (gnu packages bioinformatics)
  #:use-module (gnu packages c)
  #:use-module (gnu packages compression)
  #:use-module (gnu packages curl)
  #:use-module (gnu packages databases)
  #:use-module (gnu packages fontutils)
  #:use-module (gnu packages gcc)
  #:use-module (gnu packages geo)
  #:use-module (gnu packages ghostscript)
  #:use-module (gnu packages gl)
  #:use-module (gnu packages gnome)
  #:use-module (gnu packages graph)
  #:use-module (gnu packages gtk)
  #:use-module (gnu packages haskell-xyz)
  #:use-module (gnu packages icu4c)
  #:use-module (gnu packages image)
  #:use-module (gnu packages imagemagick)
  #:use-module (gnu packages java)
  #:use-module (gnu packages javascript)
  #:use-module (gnu packages lisp-xyz)
  #:use-module (gnu packages machine-learning)
  #:use-module (gnu packages maths)
  #:use-module (gnu packages mpi)
  #:use-module (gnu packages multiprecision)
  #:use-module (gnu packages networking)
  #:use-module (gnu packages pcre)
  #:use-module (gnu packages perl)
  #:use-module (gnu packages pkg-config)
  #:use-module (gnu packages python)
  #:use-module (gnu packages python-xyz)
  #:use-module (gnu packages statistics)
  #:use-module (gnu packages tcl)
  #:use-module (gnu packages tls)
  #:use-module (gnu packages web)
  #:use-module (gnu packages xorg))

(define-public r-clipr
  (package
    (name "r-clipr")
    (version "0.7.0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "clipr" version))
       (sha256
        (base32
         "1qn2p13d0c1bpqss6mv9hk60980rzhznfqpyaf5x0fy65svy9903"))))
    (build-system r-build-system)
    (home-page "https://github.com/mdlincoln/clipr")
    (synopsis "Read and write from the system clipboard")
    (description
     "This package provides simple utility functions to read from and write to
the system clipboards.")
    (license license:gpl3)))

(define-public r-oenb
  (package
    (name "r-oenb")
    (version "0.0.1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "oenb" version))
       (sha256
        (base32
         "1x1jlqp6r27c4gb7wafzpmh5rq6yq61a2d395r5lsmv2g5jb4biz"))))
    (properties `((upstream-name . "oenb")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-dplyr" ,r-dplyr)
       ("r-xml" ,r-xml)))
    (native-inputs `(("r-knitr" ,r-knitr)))
    (home-page "https://github.com/franzmohr/oenb")
    (synopsis "Tools for the OeNB Data Web Service")
    (description
     "Tools to access data from the data web service of the
@acronym{OeNB, Oesterreichische Nationalbank},
@url{https://www.oenb.at/en/Statistics/User-Defined-Tables/webservice.html}.")
    (license license:gpl2+)))

(define-public r-scales
  (package
    (name "r-scales")
    (version "1.1.0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "scales" version))
       (sha256
        (base32 "00rdbfj5mwc3kr8pskidn3n2zkp4ms6cx36xazz54pxw3pysdr0y"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-farver" ,r-farver)
       ("r-labeling" ,r-labeling)
       ("r-lifecycle" ,r-lifecycle)
       ("r-munsell" ,r-munsell)
       ("r-rcolorbrewer" ,r-rcolorbrewer)
       ("r-r6" ,r-r6)
       ("r-viridislite" ,r-viridislite)))
    (home-page "https://github.com/hadley/scales")
    (synopsis "Scale functions for visualization")
    (description
     "This package provides graphical scales that map data to aesthetics, and
provides methods for automatically determining breaks and labels for axes and
legends.")
    (license license:expat)))

(define-public r-pheatmap
  (package
    (name "r-pheatmap")
    (version "1.0.12")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "pheatmap" version))
       (sha256
        (base32
         "1hdh74az3vyzz6dqa311rhxdm74n46lyr03p862kn80p0kp9d7ap"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-gtable" ,r-gtable)
       ("r-rcolorbrewer" ,r-rcolorbrewer)
       ("r-scales" ,r-scales)))
    (home-page "https://cran.r-project.org/web/packages/pheatmap")
    (synopsis "Pretty heatmaps")
    (description
     "This package provides an implementation of heatmaps that offers more
control over dimensions and appearance.")
    (license license:gpl2+)))

(define-public r-ellipsis
  (package
    (name "r-ellipsis")
    (version "0.3.0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "ellipsis" version))
       (sha256
        (base32
         "01z9gq311nzwv3a0sa49jhm5ylqd59srip4vjkrf23hzgb5i9y0b"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-rlang" ,r-rlang)))
    (home-page "https://github.com/hadley/ellipsis")
    (synopsis "Tools for working with additional arguments")
    (description
     "In S3 generics, it's useful to take @code{...} so that methods can have
additional arguments.  But this flexibility comes at a cost: misspelled
arguments will be silently ignored.  The @code{ellipsis} package is an
experiment that allows a generic to warn if any arguments passed in @code{...}
are not used.")
    (license license:gpl3)))

(define-public r-grr
  (package
    (name "r-grr")
    (version "0.9.5")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "grr" version))
       (sha256
        (base32
         "0arbcgrvhkwb5xk4nry1ffg2qj0v8ivhjghdr505ib4357g0c9i9"))))
    (build-system r-build-system)
    (home-page "https://cran.r-project.org/web/packages/grr")
    (synopsis "Alternative implementations of base R functions")
    (description
     "This package provides alternative implementations of some base R
functions, including @code{sort}, @code{order}, and @code{match}.  The
functions are simplified but can be faster or have other advantages.")
    (license license:gpl3)))

(define-public r-matrix-utils
  (package
    (name "r-matrix-utils")
    (version "0.9.8")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "Matrix.utils" version))
       (sha256
        (base32
         "0a5fq1scykqk0kc9j051j6fix6j2dqwz5wbgb0amaxsiywz9vigb"))))
    (properties `((upstream-name . "Matrix.utils")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-grr" ,r-grr)
       ("r-matrix" ,r-matrix)))
    (home-page "https://github.com/cvarrichio/Matrix.utils")
    (synopsis
     "Data.frame-Like Operations on Sparse and Dense Matrix Objects")
    (description
     "This package implements data manipulation methods such as @code{cast},
@code{aggregate}, and @code{merge}/@code{join} for Matrix and Matrix-like
objects.")
    (license license:gpl3)))

(define-public r-sys
  (package
    (name "r-sys")
    (version "3.3")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "sys" version))
       (sha256
        (base32
         "14wvy46i2iz9jn7lj3cvifmps932s3395wq681hniva0f8m7q8d6"))))
    (build-system r-build-system)
    (home-page "https://github.com/jeroen/sys")
    (synopsis "Powerful and reliable tools for running system commands in R")
    (description
     "This package provides drop-in replacements for the base @code{system2()}
function with fine control and consistent behavior across platforms.  It
supports clean interruption, timeout, background tasks, and streaming STDIN /
STDOUT / STDERR over binary or text connections.  The package also provides
functions for evaluating expressions inside a temporary fork.  Such
evaluations have no side effects on the main R process, and support reliable
interrupts and timeouts.  This provides the basis for a sandboxing
mechanism.")
    (license license:expat)))

(define-public r-askpass
  (package
    (name "r-askpass")
    (version "1.1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "askpass" version))
       (sha256
        (base32
         "07q0ik8jzk44vpwh48rr3fnpd7dzsdhjjsl4l850rffv3dyq4h6v"))))
    (build-system r-build-system)
    (propagated-inputs `(("r-sys" ,r-sys)))
    (home-page "https://github.com/jeroen/askpass")
    (synopsis "Safe password entry for R")
    (description
     "This package provides cross-platform utilities for prompting the user
for credentials or a passphrase, for example to authenticate with a server or
read a protected key.")
    (license license:expat)))

(define-public r-vegan
  (package
    (name "r-vegan")
    (version "2.5-6")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "vegan" version))
       (sha256
        (base32
         "0g60rgn1i7wqf9pf5m1yki1m45gcp7i5hmjic0ci0f6vng70mh5k"))))
    (build-system r-build-system)
    (native-inputs
     `(("gfortran" ,gfortran)))
    (propagated-inputs
     `(("r-cluster" ,r-cluster)
       ("r-knitr" ,r-knitr)             ; needed for vignettes
       ("r-lattice" ,r-lattice)
       ("r-mass" ,r-mass)
       ("r-mgcv" ,r-mgcv)
       ("r-permute" ,r-permute)))
    (home-page "https://cran.r-project.org/web/packages/vegan")
    (synopsis "Functions for community ecology")
    (description
     "The vegan package provides tools for descriptive community ecology.  It
has most basic functions of diversity analysis, community ordination and
dissimilarity analysis.  Most of its multivariate tools can be used for other
data types as well.")
    (license license:gpl2+)))

(define-public r-tidyverse
  (package
    (name "r-tidyverse")
    (version "1.3.0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "tidyverse" version))
       (sha256
        (base32
         "02gyys08qv2v4cl2d66gml4d31ipxay0iyfwwksvxyclx60wp2kd"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-broom" ,r-broom)
       ("r-cli" ,r-cli)
       ("r-crayon" ,r-crayon)
       ("r-dbplyr" ,r-dbplyr)
       ("r-dplyr" ,r-dplyr)
       ("r-forcats" ,r-forcats)
       ("r-ggplot2" ,r-ggplot2)
       ("r-haven" ,r-haven)
       ("r-hms" ,r-hms)
       ("r-httr" ,r-httr)
       ("r-jsonlite" ,r-jsonlite)
       ("r-lubridate" ,r-lubridate)
       ("r-magrittr" ,r-magrittr)
       ("r-modelr" ,r-modelr)
       ("r-pillar" ,r-pillar)
       ("r-purrr" ,r-purrr)
       ("r-readr" ,r-readr)
       ("r-readxl" ,r-readxl)
       ("r-reprex" ,r-reprex)
       ("r-rlang" ,r-rlang)
       ("r-rstudioapi" ,r-rstudioapi)
       ("r-rvest" ,r-rvest)
       ("r-stringr" ,r-stringr)
       ("r-tibble" ,r-tibble)
       ("r-tidyr" ,r-tidyr)
       ("r-xml2" ,r-xml2)))
    (home-page "https://tidyverse.tidyverse.org")
    (synopsis "Install and load packages from the \"Tidyverse\"")
    (description
     "The @code{tidyverse} is a set of packages that work in harmony because
they share common data representations and API design.  This package is
designed to make it easy to install and load multiple tidyverse packages in a
single step.")
    (license license:gpl3)))

(define-public r-rvest
  (package
    (name "r-rvest")
    (version "0.3.5")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "rvest" version))
       (sha256
        (base32 "0r0a5jic09xw5pk0x42pr99r3zab5m9s4x85ymx1sl769jz42zqf"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-httr" ,r-httr)
       ("r-magrittr" ,r-magrittr)
       ("r-selectr" ,r-selectr)
       ("r-xml2" ,r-xml2)))
    (home-page "https://github.com/hadley/rvest")
    (synopsis "Simple web scraping for R")
    (description
     "@code{r-rvest} helps you scrape information from web pages.  It is
designed to work with @code{magrittr} to make it easy to express common web
scraping tasks, inspired by libraries like @code{BeautifulSoup}.")
    (license license:gpl3)))

(define-public r-selectr
  (package
    (name "r-selectr")
    (version "0.4-2")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "selectr" version))
       (sha256
        (base32 "09y1n3iy297g49xlpl7xrjpwgnm57pskx5991lyfcpizbz8ax22m"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-stringr" ,r-stringr)
       ("r-r6" ,r-r6)))
    (home-page "https://sjp.co.nz/projects/selectr/")
    (synopsis "Translate CSS selectors to XPath expressions")
    (description
     "@code{r-selectr} translates a CSS3 selector into an equivalent XPath
expression.  This allows you to use CSS selectors when working with the XML
package as it can only evaluate XPath expressions.  Also provided are
convenience functions useful for using CSS selectors on XML nodes.  This
package is a port of the Python package @code{cssselect}.")
    (license license:bsd-3)))

(define-public r-reprex
  (package
    (name "r-reprex")
    (version "0.3.0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "reprex" version))
       (sha256
        (base32
         "0v7vxzs8alwz8y1cjicpimp5yimf1g9gb8x5wy3zhvrz6kk2lg10"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-callr" ,r-callr)
       ("r-clipr" ,r-clipr)
       ("r-fs" ,r-fs)
       ("r-rlang" ,r-rlang)
       ("r-rmarkdown" ,r-rmarkdown)
       ("r-whisker" ,r-whisker)
       ("r-withr" ,r-withr)))
    (home-page "https://github.com/tidyverse/reprex")
    (synopsis "Prepare reproducible R code examples for sharing")
    (description
     "This package provides a convenience wrapper that uses the
@code{rmarkdown} package to render small snippets of code to target formats
that include both code and output.  The goal is to encourage the sharing of
small, reproducible, and runnable examples on code-oriented websites or email.
@code{reprex} also extracts clean, runnable R code from various common formats,
such as copy/paste from an R session.")
    (license license:expat)))

(define-public r-callr
  (package
    (name "r-callr")
    (version "3.4.3")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "callr" version))
       (sha256
        (base32
         "1dc20gdawy9mhnc452qlshv2p4krs6c2gymvpv365mn141zjgdq1"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-r6" ,r-r6)
       ("r-processx" ,r-processx)))
    (home-page "https://github.com/r-lib/callr#readme")
    (synopsis "Call R from R")
    (description
     "It is sometimes useful to perform a computation in a separate R process,
without affecting the current R process at all.  This package does exactly
that.")
    (license license:expat)))

(define-public r-readxl
  (package
    (name "r-readxl")
    (version "1.3.1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "readxl" version))
       (sha256
        (base32
         "15mambxr8c7k2ikdfsl1w3vxvm54dsnk0cl1qvks6iig7rql3d14"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-cellranger" ,r-cellranger)
       ("r-progress" ,r-progress)
       ("r-rcpp" ,r-rcpp)
       ("r-tibble" ,r-tibble)))
    (home-page "https://readxl.tidyverse.org")
    (synopsis "Read Excel files")
    (description
     "This package lets you import Excel files into R.  It supports
@file{.xls} via the embedded @code{libxls} C library and @file{.xlsx} via
the embedded @code{RapidXML} C++ library.")
    ;; XXX: This package bundles a copy of 'libxsl' which is BSD-2 and
    ;; 'rapidxml' which is Boost.
    (license (list license:gpl3 license:bsd-2 license:boost1.0))))

(define-public r-modelr
  (package
    (name "r-modelr")
    (version "0.1.6")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "modelr" version))
       (sha256
        (base32
         "1x2m34m4qirb401krmgc5wg3g7ndbcglfab2l0655rmky3fz7rfp"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-broom" ,r-broom)
       ("r-dplyr" ,r-dplyr)
       ("r-magrittr" ,r-magrittr)
       ("r-purrr" ,r-purrr)
       ("r-rlang" ,r-rlang)
       ("r-tibble" ,r-tibble)
       ("r-tidyr" ,r-tidyr)
       ("r-tidyselect" ,r-tidyselect)))
    (home-page "https://github.com/tidyverse/modelr")
    (synopsis "Helper functions for modelling in pipelines")
    (description
     "Functions for modelling that help you seamlessly integrate modelling
into a pipeline of data manipulation and visualisation.")
    (license license:gpl3)))

(define-public r-httpuv
  (package
    (name "r-httpuv")
    (version "1.5.2")
    (source (origin
              (method url-fetch)
              (uri (cran-uri "httpuv" version))
              (sha256
               (base32
                "13ax0hs2lc39ilznh1zarwqdzahcbhb8adilrfik3xg0fkljpcwk"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-bh" ,r-bh)
       ("r-later" ,r-later)
       ("r-promises" ,r-promises)
       ("r-r6" ,r-r6)
       ("r-rcpp" ,r-rcpp)))
    (home-page "https://github.com/rstudio/httpuv")
    (synopsis "HTTP and WebSocket server library for R")
    (description
     "The httpuv package provides low-level socket and protocol support for
handling HTTP and WebSocket requests directly from within R.  It is primarily
intended as a building block for other packages, rather than making it
particularly easy to create complete web applications using httpuv alone.")
    ;; This package includes third-party code that was originally released
    ;; under various non-copyleft licenses.  Full licensing information can be
    ;; obtained here: https://github.com/rstudio/httpuv/blob/master/LICENSE
    (license license:gpl3+)))

(define-public r-jsonlite
  (package
    (name "r-jsonlite")
    (version "1.6.1")
    (source (origin
              (method url-fetch)
              (uri (cran-uri "jsonlite" version))
              (sha256
               (base32
                "0xrki07wc17bkmhz0h7jay784j1sls2i9bf1mfpj6yl59791v4kl"))))
    (build-system r-build-system)
    (home-page "https://arxiv.org/abs/1403.2805")
    (synopsis "Robust, high performance JSON parser and generator for R")
    (description
     "The jsonlite package provides a fast JSON parser and generator optimized
for statistical data and the web.  It offers flexible, robust, high
performance tools for working with JSON in R and is particularly powerful for
building pipelines and interacting with a web API.  In addition to converting
JSON data from/to R objects, jsonlite contains functions to stream, validate,
and prettify JSON data.  The unit tests included with the package verify that
all edge cases are encoded and decoded consistently for use with dynamic data
in systems and applications.")
    (license license:expat)))

(define-public r-servr
  (package
    (name "r-servr")
    (version "0.16")
    (source (origin
              (method url-fetch)
              (uri (cran-uri "servr" version))
              (sha256
               (base32
                "106skz04iq4dkblr17idxsxfcfqic6rcaz8mahydkwjjppnhp5fc"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-httpuv" ,r-httpuv)
       ("r-jsonlite" ,r-jsonlite)
       ("r-mime" ,r-mime)
       ("r-xfun" ,r-xfun)))
    (home-page "https://github.com/yihui/servr")
    (synopsis "Simple HTTP server to serve static files or dynamic documents")
    (description
     "Servr provides an HTTP server in R to serve static files, or dynamic
documents that can be converted to HTML files (e.g., R Markdown) under a given
directory.")
    (license license:expat)))

(define-public r-htmltools
  (package
    (name "r-htmltools")
    (version "0.4.0")
    (source (origin
              (method url-fetch)
              (uri (cran-uri "htmltools" version))
              (sha256
               (base32
                "06l17d8jkf438yk2mchpsp4j90bynnapz3nabh5vkcc324p5a62v"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-digest" ,r-digest)
       ("r-rcpp" ,r-rcpp)
       ("r-rlang" ,r-rlang)))
    (home-page "https://cran.r-project.org/web/packages/htmltools")
    (synopsis "R tools for HTML")
    (description
     "This package provides tools for HTML generation and output in R.")
    (license license:expat)))

(define-public r-htmlwidgets
  (package
    (name "r-htmlwidgets")
    (version "1.5.1")
    (source (origin
              (method url-fetch)
              (uri (cran-uri "htmlwidgets" version))
              (sha256
               (base32
                "10fp306l1nybkah6jrlrqwwdb6zvklbddp8i3w9v9naj8la5jbnl"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-htmltools" ,r-htmltools)
       ("r-jsonlite" ,r-jsonlite)
       ("r-yaml" ,r-yaml)))
    (home-page "https://github.com/ramnathv/htmlwidgets")
    (synopsis "HTML Widgets for R")
    (description
     "HTML widgets is a framework for creating HTML widgets that render in
various contexts including the R console, R Markdown documents, and Shiny web
applications.")
    (license license:expat)))

(define-public r-htmltable
  (package
    (name "r-htmltable")
    (version "1.13.3")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "htmlTable" version))
       (sha256
        (base32
         "0g9r156k9yl1f092hfw3b9wjx11akf0shbi3x0d0mvpnflvc8nfl"))))
    (properties `((upstream-name . "htmlTable")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-checkmate" ,r-checkmate)
       ("r-htmltools" ,r-htmltools)
       ("r-htmlwidgets" ,r-htmlwidgets)
       ("r-knitr" ,r-knitr)
       ("r-magrittr" ,r-magrittr)
       ("r-rstudioapi" ,r-rstudioapi)
       ("r-stringr" ,r-stringr)))
    (home-page "http://gforge.se/packages/")
    (synopsis "Advanced tables for Markdown/HTML")
    (description
     "This package provides functions to build tables with advanced layout
elements such as row spanners, column spanners, table spanners, zebra
striping, and more.  While allowing advanced layout, the underlying
CSS-structure is simple in order to maximize compatibility with word
processors such as LibreOffice.  The package also contains a few text
formatting functions that help outputting text compatible with HTML or
LaTeX.")
    (license license:gpl3+)))

(define-public r-curl
  (package
    (name "r-curl")
    (version "4.3")
    (source (origin
              (method url-fetch)
              (uri (cran-uri "curl" version))
              (sha256
               (base32
                "1nrf6md41b37j424y6rvifdj9zb3j14f60fj7q71k9jhpf2x81kl"))))
    (build-system r-build-system)
    (arguments
     `(#:phases
       (modify-phases %standard-phases
         ;; The environment variable CURL_CA_BUNDLE is only respected when
         ;; running Windows, so we disable the platform checks.
         ;; This can be removed once the libcurl has been patched.
         (add-after 'unpack 'allow-CURL_CA_BUNDLE
           (lambda _
             (substitute* "R/onload.R"
               (("if \\(!grepl\\(\"mingw\".*")
                "if (FALSE)\n"))
             (substitute* "src/handle.c"
               (("/\\* Only set" m)
                (string-append "\
const char *_ca_bundle = getenv(\"CURL_CA_BUNDLE\");
if(_ca_bundle != NULL) { curl_easy_setopt(handle, CURLOPT_CAINFO, _ca_bundle); }
" m)))
             #t)))))
    (inputs
     `(("libcurl" ,curl)
       ("zlib" ,zlib)))
    (native-inputs
     `(("pkg-config" ,pkg-config)))
    (home-page "https://github.com/jeroenooms/curl")
    (synopsis "HTTP client for R")
    (description
     "The @code{curl()} and @code{curl_download()} functions provide highly
configurable drop-in replacements for base @code{url()} and
@code{download.file()} with better performance, support for encryption, gzip
compression, authentication, and other @code{libcurl} goodies.  The core of
the package implements a framework for performing fully customized requests
where data can be processed either in memory, on disk, or streaming via the
callback or connection interfaces.")
    (license license:expat)))

(define-public r-hwriter
  (package
    (name "r-hwriter")
    (version "1.3.2")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "hwriter" version))
       (sha256
        (base32
         "0arjsz854rfkfqhgvpqbm9lfni97dcjs66isdsfvwfd2wz932dbb"))))
    (build-system r-build-system)
    (home-page "https://cran.r-project.org/web/packages/hwriter")
    (synopsis "Output R objects in HTML format")
    (description
     "This package provides easy-to-use and versatile functions to output R
objects in HTML format.")
    (license license:lgpl2.1+)))

(define-public r-rjson
  (package
    (name "r-rjson")
    (version "0.2.20")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "rjson" version))
       (sha256
        (base32
         "0v1zvdd3svnavklh7y5xbwrrkbvx6053r4c5hgnk7hz7bqg7qa1s"))))
    (build-system r-build-system)
    (home-page "https://cran.r-project.org/web/packages/rjson")
    (synopsis "JSON library for R")
    (description
     "This package provides functions to convert R objects into JSON objects
and vice-versa.")
    (license license:gpl2+)))

(define-public r-fastmap
  (package
    (name "r-fastmap")
    (version "1.0.1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "fastmap" version))
       (sha256
        (base32
         "1v7sp56xiha0bh78g3w92k52p9vkp7ryzpw0z66nyddxzrfv0y27"))))
    (properties `((upstream-name . "fastmap")))
    (build-system r-build-system)
    (home-page "https://r-lib.github.io/fastmap/")
    (synopsis "Fast implementation of a key-value store")
    (description
     "This package provides a fast implementation of a key-value store.
Environments are commonly used as key-value stores, but every time a new key
is used, it is added to R's global symbol table, causing a small amount of
memory leakage.  This can be problematic in cases where many different keys
are used.  Fastmap avoids this memory leak issue by implementing the map using
data structures in C++.")
    (license license:expat)))

(define-public r-shiny
  (package
    (name "r-shiny")
    (version "1.4.0.2")
    (source
     (origin
       (method git-fetch)
       (uri (git-reference
             (url "https://github.com/rstudio/shiny.git")
             (commit (string-append "v" version))))
       (file-name (git-file-name name version))
       (sha256
        (base32
         "005wgcxq7f2q9g6wvfk29n2nms262w0abpz93sfvx79yv6qxppzs"))))
    (build-system r-build-system)
    (arguments
     `(#:modules ((guix build r-build-system)
                  (guix build minify-build-system)
                  (guix build utils)
                  (ice-9 match))
       #:imported-modules (,@%r-build-system-modules
                           (guix build minify-build-system))
       #:phases
       (modify-phases (@ (guix build r-build-system) %standard-phases)
         (add-after 'unpack 'replace-bundled-minified-JavaScript
           (lambda* (#:key inputs #:allow-other-keys)
             (let ((replace-file (lambda (old new)
                                   (format #t "replacing ~a with ~a\n" old new)
                                   (delete-file old)
                                   (symlink new old))))
               ;; NOTE: Files in ./inst/www/shared/datepicker/js/locales/
               ;; contain just data.  They are not minified code, so we don't
               ;; replace them.
               (with-directory-excursion "inst/www/shared"
                 (replace-file "bootstrap/shim/respond.min.js"
                               (string-append (assoc-ref inputs "js-respond")
                                              "/share/javascript/respond.min.js"))
                 (replace-file "bootstrap/shim/html5shiv.min.js"
                               (string-append (assoc-ref inputs "js-html5shiv")
                                              "/share/javascript/html5shiv.min.js"))
                 (replace-file "json2-min.js"
                               (string-append (assoc-ref inputs "js-json2")
                                              "/share/javascript/json2-min.js"))
                 (replace-file "strftime/strftime-min.js"
                               (string-append (assoc-ref inputs "js-strftime")
                                              "/share/javascript/strftime.min.js"))
                 (replace-file "highlight/highlight.pack.js"
                               (string-append (assoc-ref inputs "js-highlight")
                                              "/share/javascript/highlight.min.js"))
                 (replace-file "datatables/js/jquery.dataTables.min.js"
                               (string-append (assoc-ref inputs "js-datatables")
                                              "/share/javascript/jquery.dataTables.min.js"))
                 (replace-file "selectize/js/selectize.min.js"
                               (string-append (assoc-ref inputs "js-selectize")
                                              "/share/javascript/selectize.min.js"))
                 (replace-file "selectize/js/es5-shim.min.js"
                               (string-append (assoc-ref inputs "js-es5-shim")
                                              "/share/javascript/es5-shim.min.js"))
                 (for-each (match-lambda
                             ((source . target)
                              (delete-file target)
                              (minify source #:target target)))
                           '(("jqueryui/jquery-ui.js" .
                              "jqueryui/jquery-ui.min.js")
                             ("datepicker/js/bootstrap-datepicker.js" .
                              "datepicker/js/bootstrap-datepicker.min.js")
                             ("ionrangeslider/js/ion.rangeSlider.js" .
                              "ionrangeslider/js/ion.rangeSlider.min.js")
                             ("bootstrap/js/bootstrap.js" .
                              "bootstrap/js/bootstrap.min.js")
                             ("shiny.js" .
                              "shiny.min.js")
                             ("jquery.js" .
                              "jquery.min.js")
                             ("legacy/jquery.js" .
                              "legacy/jquery.min.js")
                             ("showdown/src/showdown.js" .
                              "showdown/compressed/showdown.js")))))
             #t)))))
    (propagated-inputs
     `(("r-crayon" ,r-crayon)
       ("r-digest" ,r-digest)
       ("r-fastmap" ,r-fastmap)
       ("r-htmltools" ,r-htmltools)
       ("r-httpuv" ,r-httpuv)
       ("r-jsonlite" ,r-jsonlite)
       ("r-later" ,r-later)
       ("r-mime" ,r-mime)
       ("r-promises" ,r-promises)
       ("r-r6" ,r-r6)
       ("r-rlang" ,r-rlang)
       ("r-sourcetools" ,r-sourcetools)
       ("r-withr" ,r-withr)
       ("r-xtable" ,r-xtable)))
    (inputs
     `(("js-datatables" ,js-datatables)
       ("js-html5shiv" ,js-html5shiv)
       ("js-json2" ,js-json2)
       ("js-respond" ,js-respond)
       ("js-selectize" ,js-selectize)
       ("js-strftime" ,js-strftime)
       ("js-highlight" ,js-highlight)
       ("js-es5-shim" ,js-es5-shim)))
    (native-inputs
     `(("uglify-js" ,uglify-js)
       ("gfortran" ,gfortran)))
    (home-page "http://shiny.rstudio.com")
    (synopsis "Easy interactive web applications with R")
    (description
     "Makes it incredibly easy to build interactive web applications
with R.  Automatic \"reactive\" binding between inputs and outputs and
extensive prebuilt widgets make it possible to build beautiful,
responsive, and powerful applications with minimal effort.")
    (license license:artistic2.0)))

;; This package includes minified JavaScript files.  When upgrading please
;; check that there are no new minified JavaScript files.
(define-public r-shinytree
  (package
    (name "r-shinytree")
    (version "0.2.7")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "shinyTree" version))
       (sha256
        (base32
         "0jfx2capckv7hf2yx3fn8i4rcmhi222ah91jnmhg497x8wgz31s3"))
       (modules '((guix build utils)))
       (snippet
        '(begin
           ;; Delete minified JavaScript
           (for-each delete-file
                     '("inst/www/jsTree-3.3.7/libs/require.js"
                       "inst/www/jsTree-3.3.7/libs/jquery.js"
                       "inst/www/jsTree-3.3.7/jstree.min.js"))
           #t))))
    (properties `((upstream-name . "shinyTree")))
    (build-system r-build-system)
    (arguments
     `(#:modules ((guix build utils)
                  (guix build r-build-system)
                  (srfi srfi-1)
                  (ice-9 popen))
       #:phases
       (modify-phases %standard-phases
         (add-after 'unpack 'replace-minified-javascript
           (lambda* (#:key inputs #:allow-other-keys)
             (with-directory-excursion "inst/www/jsTree-3.3.7/"
               (symlink (string-append (assoc-ref inputs "js-requirejs")
                                       "/share/javascript/require.min.js")
                        "libs/require.js")
               (call-with-values
                   (lambda ()
                     (unzip2
                      `((,(assoc-ref inputs "js-jquery")
                         "libs/jquery.js")
                        ("jstree.js"
                         "jstree.min.js"))))
                 (lambda (sources targets)
                   (for-each (lambda (source target)
                               (format #t "Processing ~a --> ~a~%"
                                       source target)
                               (let ((minified (open-pipe* OPEN_READ "uglify-js" source)))
                                 (call-with-output-file target
                                   (lambda (port)
                                     (dump-port minified port)))))
                             sources targets))))
             #t)))))
    (propagated-inputs
     `(("r-htmlwidgets" ,r-htmlwidgets)
       ("r-jsonlite" ,r-jsonlite)
       ("r-promises" ,r-promises)
       ("r-shiny" ,r-shiny)
       ("r-stringr" ,r-stringr)))
    (inputs
     `(("js-requirejs" ,js-requirejs)))
    (native-inputs
     `(("uglify-js" ,uglify-js)
       ("js-jquery"
        ,(origin
           (method url-fetch)
           (uri "https://code.jquery.com/jquery-3.3.1.js")
           (sha256
            (base32
             "1b8zxrp6xwzpw25apn8j4qws0f6sr7qr7h2va5h1mjyfqvn29anq"))))))
    (home-page "https://cran.r-project.org/web/packages/shinyTree/")
    (synopsis "jsTree bindings for Shiny")
    (description
     "This package exposes R bindings to jsTree, a JavaScript library that
supports interactive trees, to enable rich, editable trees in Shiny.")
    (license license:expat)))

(define-public r-shinydashboard
  (package
    (name "r-shinydashboard")
    (version "0.7.1")
    (source (origin
              (method url-fetch)
              (uri (cran-uri "shinydashboard" version))
              (sha256
               (base32
                "0khac8b27q3swdw07kl609hm0fjfjsjv591b388q99mqqr2rk92i"))))
    (build-system r-build-system)
    ;; The directory inst/AdminLTE/ contains a minified JavaScript file.
    ;; Regenerate it from the included sources.
    (arguments
     `(#:modules ((guix build utils)
                  (guix build r-build-system)
                  (ice-9 popen))
       #:phases
       (modify-phases %standard-phases
         (add-after 'unpack 'generate-minified-javascript
           (lambda _
             (with-directory-excursion "inst/AdminLTE"
               (delete-file "app.min.js")
               (let ((minified (open-pipe* OPEN_READ "uglify-js" "app.js")))
                 (call-with-output-file "app.min.js"
                   (lambda (port)
                     (dump-port minified port))))))))))
    (propagated-inputs
     `(("r-htmltools" ,r-htmltools)
       ("r-promises" ,r-promises)
       ("r-shiny" ,r-shiny)))
    (native-inputs
     `(("uglify-js" ,uglify-js)))
    (home-page "https://rstudio.github.io/shinydashboard/")
    (synopsis "Create dashboards with shiny")
    (description "This package provides an extension to the Shiny web
application framework for R, making it easy to create attractive dashboards.")
    ;; This package includes software that was released under the Expat
    ;; license, but the whole package is released under GPL version 2 or
    ;; later.
    (license license:gpl2+)))

(define-public r-shinyfiles
  (package
    (name "r-shinyfiles")
    (version "0.7.5")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "shinyFiles" version))
       (sha256
        (base32 "1143m941hma9hc77c3xcw26c0ygfhn9ii2sbp9wrydxv4gc7mr8a"))))
    (properties `((upstream-name . "shinyFiles")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-fs" ,r-fs)
       ("r-htmltools" ,r-htmltools)
       ("r-jsonlite" ,r-jsonlite)
       ("r-shiny" ,r-shiny)
       ("r-tibble" ,r-tibble)))
    (home-page "https://github.com/thomasp85/shinyFiles")
    (synopsis "Server-side file system viewer for Shiny")
    (description
     "This package provides functionality for client-side navigation of the
server side file system in shiny apps.  In case the app is running locally
this gives the user direct access to the file system without the need to
\"download\" files to a temporary location.  Both file and folder selection as
well as file saving is available.")
    (license license:gpl2+)))

(define-public r-shinythemes
  (package
    (name "r-shinythemes")
    (version "1.1.2")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "shinythemes" version))
       (sha256
        (base32
         "12miz44n2zxfswnia7p8dirxj3miw0aqn4pkx2111ikz67ax84rf"))))
    (properties `((upstream-name . "shinythemes")))
    (build-system r-build-system)
    (propagated-inputs `(("r-shiny" ,r-shiny)))
    (home-page "https://rstudio.github.io/shinythemes/")
    (synopsis "Themes for Shiny")
    (description
     "This package provides themes for use with Shiny.  It includes several
Bootstrap themes, which are packaged for use with Shiny applications.")
    ;; The package is released under version 3 of the GPL, but it includes
    ;; source files that are covered by the Expat license.  It also includes
    ;; fonts under SIL or the ASL.
    (license (list license:gpl3 license:expat
                   license:silofl1.1 license:asl2.0))))

;; The package sources include minified variants of d3.js and non-minified
;; source code of d3-jetpack.
(define-public r-d3r
  (package
    (name "r-d3r")
    (version "0.8.7")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "d3r" version))
       (sha256
        (base32
         "0xl3im76lp7pd5lhp8jfyqdm4j4zvjrx5a5fl81xv2cf7x3n4f2a"))))
    (build-system r-build-system)
    (arguments
     `(#:modules ((guix build utils)
                  (guix build r-build-system)
                  (srfi srfi-1)
                  (ice-9 popen))
       #:phases
       (modify-phases %standard-phases
         (add-after 'unpack 'process-javascript
           (lambda* (#:key inputs #:allow-other-keys)
             (with-directory-excursion "inst/www/d3/"
               (call-with-values
                   (lambda ()
                     (unzip2
                      `((,(assoc-ref inputs "d3.v3.js")
                         "v3/dist/d3.min.js")
                        (,(assoc-ref inputs "d3.v4.js")
                         "v4/dist/d3.min.js")
                        (,(assoc-ref inputs "d3.v5.js")
                         "v5/dist/d3.min.js"))))
                 (lambda (sources targets)
                   (for-each (lambda (source target)
                               (format #t "Processing ~a --> ~a~%"
                                       source target)
                               (delete-file target)
                               (let ((minified (open-pipe* OPEN_READ "uglify-js" source)))
                                 (call-with-output-file target
                                   (lambda (port)
                                     (dump-port minified port)))))
                             sources targets))))
             #t)))))
    (propagated-inputs
     `(("r-dplyr" ,r-dplyr)
       ("r-htmltools" ,r-htmltools)
       ("r-tidyr" ,r-tidyr)))
    (native-inputs
     `(("uglify-js" ,uglify-js)
       ("d3.v3.js"
        ,(origin
           (method url-fetch)
           (uri "https://d3js.org/d3.v3.js")
           (sha256
            (base32
             "1arr7sr08vy7wh0nvip2mi7dpyjw4576vf3bm45rp4g5lc1k1x41"))))
       ("d3.v4.js"
        ,(origin
           (method url-fetch)
           (uri "https://d3js.org/d3.v4.js")
           (sha256
            (base32
             "0y7byf6kcinfz9ac59jxc4v6kppdazmnyqfav0dm4h550fzfqqlg"))))
       ("d3.v5.js"
        ,(origin
           (method url-fetch)
           (uri "https://d3js.org/d3.v5.js")
           (sha256
            (base32
             "0kxvx5pfagxn6nhavdwsdnzyd26g0z5dsfi1pi5dvcmb0c8ipcdn"))))))
    (home-page "https://github.com/timelyportfolio/d3r")
    (synopsis "d3.js utilities for R")
    (description
     "This package provides a suite of functions to help ease the use of the
d3.js visualization library in R.  These helpers include
@code{htmltools::htmlDependency} functions, hierarchy builders, and conversion
tools for @code{partykit}, @code{igraph}, @code{table}, and @code{data.frame}
R objects into the JSON format that the d3.js library expects.")
    (license license:bsd-3)))

;; We use the latest commit here because the last release was in 2016 while
;; the latest commit was in 2018.
(define-public r-sankeyd3
  (let ((commit "fd50a74e29056e0d67d75b4d04de47afb2f932bc")
        (revision "1"))
    (package
      (name "r-sankeyd3")
      (version (git-version "0.3.2" revision commit))
      (source
       (origin
         (method git-fetch)
         (uri (git-reference
               (url "https://github.com/fbreitwieser/sankeyD3.git")
               (commit commit)))
         (file-name (git-file-name name version))
         (sha256
          (base32
           "0jrcnfax321pszbpjdifnkbrgbjr43bjzvlzv1p5a8wskksqwiyx"))))
      (build-system r-build-system)
      (propagated-inputs
       `(("r-d3r" ,r-d3r)
         ("r-htmlwidgets" ,r-htmlwidgets)
         ("r-shiny" ,r-shiny)
         ("r-magrittr" ,r-magrittr)))
      (home-page "https://github.com/fbreitwieser/sankeyD3")
      (synopsis "Sankey network graphs from R")
      (description
       "This package provides an R library to generate Sankey network graphs
in R and Shiny via the D3 visualization library.")
      ;; The R code is licensed under GPLv3+.  It includes the non-minified
      ;; JavaScript source code of d3-sankey, which is released under the
      ;; 3-clause BSD license.
      (license (list license:gpl3+ license:bsd-3)))))

(define-public r-crosstalk
  (package
    (name "r-crosstalk")
    (version "1.1.0.1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "crosstalk" version))
       (sha256
        (base32
         "03ihj7cimkklrbad9zic78xsrfcisygmgy859hqnx0hiph80p9rn"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-htmltools" ,r-htmltools)
       ("r-jsonlite" ,r-jsonlite)
       ("r-lazyeval" ,r-lazyeval)
       ("r-r6" ,r-r6)))
    (home-page "https://rstudio.github.io/crosstalk/")
    (synopsis "Inter-widget interactivity for HTML widgets")
    (description
     "This package provides building blocks for allowing HTML widgets to
communicate with each other, with Shiny or without (i.e.  static @code{.html}
files).  It currently supports linked brushing and filtering.")
    (license license:expat)))

(define-public r-rook
  (package
    (name "r-rook")
    (version "1.1-1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "Rook" version))
       (sha256
        (base32
         "00s9a0kr9rwxvlq433daxjk4ji8m0w60hjdprf502msw9kxfrx00"))))
    (properties `((upstream-name . "Rook")))
    (build-system r-build-system)
    (propagated-inputs `(("r-brew" ,r-brew)))
    (home-page "https://cran.r-project.org/web/packages/Rook")
    (synopsis "Web server interface for R")
    (description
     "This package contains the Rook specification and convenience software
for building and running Rook applications.  A Rook application is an R
reference class object that implements a @code{call} method or an R closure
that takes exactly one argument, an environment, and returns a list with three
named elements: the @code{status}, the @code{headers}, and the @code{body}.")
    (license license:gpl2)))

(define-public r-miniui
  (package
    (name "r-miniui")
    (version "0.1.1.1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "miniUI" version))
       (sha256
        (base32
         "1h5h2sc57h95d6bsgs95l26911g38hvjc1v50bc31xl9689l2as5"))))
    (properties `((upstream-name . "miniUI")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-htmltools" ,r-htmltools)
       ("r-shiny" ,r-shiny)))
    (home-page "https://cran.r-project.org/web/packages/miniUI/")
    (synopsis "Shiny UI widgets for small screens")
    (description
     "This package provides UI widget and layout functions for writing Shiny apps that
work well on small screens.")
    (license license:gpl3)))

(define-public r-feather
  (package
    (name "r-feather")
    (version "0.3.5")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "feather" version))
       (sha256
        (base32
         "1gxd0h2m56sjjlzn4dry6s13nddxc4l5i11gsvavaf2dwbahdzsh"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-hms" ,r-hms)
       ("r-rcpp" ,r-rcpp)
       ("r-tibble" ,r-tibble)))
    (home-page "https://github.com/wesm/feather")
    (synopsis "R Bindings to the Feather API")
    (description "Read and write feather files, a lightweight binary columnar
data store designed for maximum speed.")
    (license license:asl2.0)))

(define-public r-maps
  (package
    (name "r-maps")
    (version "3.3.0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "maps" version))
       (sha256
        (base32
         "05i2ppl5z4p8rawgqmy3z4ia05fcblpq1vvrmrkgkkpdlhczx6hr"))))
    (build-system r-build-system)
    (home-page "https://cran.r-project.org/web/packages/maps")
    (synopsis "Draw geographical maps")
    (description "This package provides an R module for display of maps.
Projection code and larger maps are in separate packages (@code{mapproj} and
@code{mapdata}).")
    (license license:gpl2)))

(define-public r-mapproj
  (package
    (name "r-mapproj")
    (version "1.2.7")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "mapproj" version))
       (sha256
        (base32
         "0nscsfq8md6ri9258xz57c3dj81wdl6kdwf4a9qcrwwbn20i427h"))))
    (build-system r-build-system)
    (propagated-inputs `(("r-maps" ,r-maps)))
    (home-page "https://cran.r-project.org/web/packages/mapproj")
    (synopsis "Map projection in R")
    (description "This package converts latitude/longitude into projected
coordinates.")
    (license (list license:gpl2          ; The R interface
                   (license:non-copyleft ; The C code
                    "https://www.gnu.org/licenses/license-list.en.html#lucent102"
                    "Lucent Public License Version 1.02")))))

(define-public r-rgooglemaps
  (package
    (name "r-rgooglemaps")
    (version "1.4.5.3")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "RgoogleMaps" version))
       (sha256
        (base32
         "02v8k0bw70q4qwx4lcdy8p25q7n3ql2ll46lfpqllxa1p26svmfi"))))
    (properties `((upstream-name . "RgoogleMaps")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-png" ,r-png)
       ("r-sp" ,r-sp)))
    (home-page "https://cran.r-project.org/web/packages/RgoogleMaps")
    (synopsis "Use Google Maps in R")
    (description "This package serves two purposes:
@enumerate
@item Provide a comfortable R interface to query the Google server for static
  maps, and
@item Use the map as a background image to overlay plots within R.  This
  requires proper coordinate scaling.
@end enumerate\n")
    (license license:gpl2+)))

(define-public r-geosphere
  (package
    (name "r-geosphere")
    (version "1.5-10")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "geosphere" version))
       (sha256
        (base32
         "15xlgsmn0vwky1l13n6acdz6jn2b2na3gf6x367y3qh1f5w4zkan"))))
    (build-system r-build-system)
    (propagated-inputs `(("r-sp" ,r-sp)))
    (home-page "https://cran.r-project.org/web/packages/geosphere")
    (synopsis "Spherical trigonometry")
    (description "This package computes spherical trigonometry for geographic
applications.  That is, compute distances and related measures for angular
(longitude/latitude) locations.")
    (license license:gpl3+)))

(define-public r-jpeg
  (package
    (name "r-jpeg")
    (version "0.1-8.1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "jpeg" version))
       (sha256
        (base32
         "1a8mi70x79a691r40yiw684jkg1mr9n8agkxlcksxcnrdybs9c0x"))))
    (build-system r-build-system)
    (inputs `(("libjpeg" ,libjpeg)))
    (home-page "https://www.rforge.net/jpeg/")
    (synopsis "Read and write JPEG images with R")
    (description "This package provides a way to read, write and display
bitmap images stored in the JPEG format with R.  It can read and write both
files and in-memory raw vectors.")
    (license license:gpl2+)))

(define-public r-ggmap
  (package
    (name "r-ggmap")
    (version "3.0.0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "ggmap" version))
       (sha256
        (base32
         "13dmzl6z62pzjiffilarkji46vy0sacxa8a7mhrhc3biq3ylzhln"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-bitops" ,r-bitops)
       ("r-digest" ,r-digest)
       ("r-dplyr" ,r-dplyr)
       ("r-ggplot2" ,r-ggplot2)
       ("r-glue" ,r-glue)
       ("r-httr" ,r-httr)
       ("r-jpeg" ,r-jpeg)
       ("r-magrittr" ,r-magrittr)
       ("r-plyr" ,r-plyr)
       ("r-png" ,r-png)
       ("r-purrr" ,r-purrr)
       ("r-rgooglemaps" ,r-rgooglemaps)
       ("r-rjson" ,r-rjson)
       ("r-scales" ,r-scales)
       ("r-stringr" ,r-stringr)
       ("r-tibble" ,r-tibble)
       ("r-tidyr" ,r-tidyr)))
    (home-page "https://github.com/dkahle/ggmap")
    (synopsis "Spatial visualization with ggplot2")
    (description "This package provides a collection of functions to visualize
spatial data and models on top of static maps from various online sources (e.g
Google Maps and Stamen Maps).  It includes tools common to those tasks,
including functions for geolocation and routing.")
    (license license:gpl2)))

(define-public r-haven
  (package
    (name "r-haven")
    (version "2.2.0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "haven" version))
       (sha256
        (base32
         "0g9d6mxqmrw2zdms78jpx2sx73pczlyy771v1h5hmxqz9sqyk7hr"))))
    (build-system r-build-system)
    (inputs
     `(("zlib" ,zlib)))
    (propagated-inputs
     `(("r-forcats" ,r-forcats)
       ("r-hms" ,r-hms)
       ("r-rcpp" ,r-rcpp)
       ("r-rlang" ,r-rlang)
       ("r-readr" ,r-readr)
       ("r-tibble" ,r-tibble)
       ("r-tidyselect" ,r-tidyselect)))
    (home-page "https://haven.tidyverse.org")
    (synopsis "Import and Export 'SPSS', 'Stata' and 'SAS' Files")
    (description
     "This package lets you mport foreign statistical formats into R via the
embedded @url{https://github.com/WizardMac/ReadStat,ReadStat} C library.")
    (license license:expat)))

(define-public r-amap
  (package
    (name "r-amap")
    (version "0.8-18")
    (source (origin
              (method url-fetch)
              (uri (cran-uri "amap" version))
              (sha256
               (base32
                "0zpcb73w413na23f6giml9311jh0j0y766w2fh9i40d2h7bbvyvs"))))
    (build-system r-build-system)
    (native-inputs
     `(("gfortran" ,gfortran)))
    (home-page "http://mulcyber.toulouse.inra.fr/projects/amap/")
    (synopsis "Another multidimensional analysis package")
    (description "This package provides tools for clustering and principal
component analysis (with robust methods, and parallelized functions).")
    (license license:gpl2+)))

(define-public r-ape
  (package
    (name "r-ape")
    (version "5.3")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "ape" version))
       (sha256
        (base32
         "08wbk1kxhs32bmmvqlqanbdg1w235amd35k8m00fngsj9h9xzc08"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-lattice" ,r-lattice)
       ("r-nlme" ,r-nlme)
       ("r-rcpp" ,r-rcpp)))
    (home-page "http://ape-package.ird.fr/")
    (synopsis "Analyses of phylogenetics and evolution")
    (description
     "This package provides functions for reading, writing, plotting, and
manipulating phylogenetic trees, analyses of comparative data in a
phylogenetic framework, ancestral character analyses, analyses of
diversification and macroevolution, computing distances from DNA sequences,
and several other tools.")
    (license license:gpl2+)))

(define-public r-abbyyr
  (package
    (name "r-abbyyr")
    (version "0.5.5")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "abbyyR" version))
       (sha256
        (base32
         "1vldnd3dg89aj6a73nhirirqddbfdrnzhb5m3679i60sark8nk6r"))))
    (properties `((upstream-name . "abbyyR")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-curl" ,r-curl)
       ("r-httr" ,r-httr)
       ("r-plyr" ,r-plyr)
       ("r-progress" ,r-progress)
       ("r-readr" ,r-readr)
       ("r-xml" ,r-xml)))
    (home-page "https://github.com/soodoku/abbyyR")
    (synopsis "Access to Abbyy Optical Character Recognition (OCR) API")
    (description
     "This package provides tools to get text from images of text using Abbyy
Cloud Optical Character Recognition (OCR) API.  With abbyyyR, one can easily
OCR images, barcodes, forms, documents with machine readable zones, e.g.
passports and get the results in a variety of formats including plain text and
XML.  To learn more about the Abbyy OCR API, see @url{http://ocrsdk.com/}.")
    (license license:expat)))

(define-public r-colorspace
  (package
    (name "r-colorspace")
    (version "1.4-1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "colorspace" version))
       (sha256
        (base32 "0wyny3ah2d74hqv80s6imrarpna09gq3j9rjnz6zx2qg0lx72gb9"))))
    (build-system r-build-system)
    (home-page "https://cran.r-project.org/web/packages/colorspace")
    (synopsis "Color space manipulation")
    (description
     "This package carries out a mapping between assorted color spaces
including RGB, HSV, HLS, CIEXYZ, CIELUV, HCL (polar CIELUV), CIELAB and polar
CIELAB.  Qualitative, sequential, and diverging color palettes based on HCL
colors are provided.")
    (license license:bsd-3)))

(define-public r-glue
  (package
    (name "r-glue")
    (version "1.3.2")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "glue" version))
       (sha256
        (base32
         "0alklqcf68kmccssp4j7a7fv553pyqyy6mkkfslav83inppm4d3g"))))
    (build-system r-build-system)
    (home-page "https://github.com/tidyverse/glue")
    (synopsis "Interpreted string literals")
    (description
     "This package provides an implementation of interpreted string literals,
inspired by Python's Literal String Interpolation (PEP-0498) and
Docstrings (PEP-0257) and Julia's Triple-Quoted String Literals.")
    (license license:expat)))

(define-public r-pastecs
  (package
   (name "r-pastecs")
   (version "1.3.21")
   (source (origin
            (method url-fetch)
            (uri (cran-uri "pastecs" version))
            (sha256
             (base32
              "0z4dic94ar646w7zc2ggi5hgvf2qnznsani94c5pyql8zspz47lc"))))
   (build-system r-build-system)
   (propagated-inputs
    `(("r-boot" ,r-boot)))
   (home-page "http://www.sciviews.org/pastecs")
   (synopsis "Analysis of space-time ecological series")
   (description
    "This package provides functions for regulation, decomposition and analysis
of space-time series.  The @code{pastecs} library is a PNEC-Art4 and IFREMER
initiative to bring PASSTEC 2000 functionalities to R.")
   (license license:gpl2+)))

(define-public r-plogr
  (package
    (name "r-plogr")
    (version "0.2.0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "plogr" version))
       (sha256
        (base32
         "0a8dhzlna79ggyhfr0nncgh15a9n6r0dsz664pz0ah323wpblqqf"))))
    (build-system r-build-system)
    (home-page "https://github.com/krlmlr/plogr")
    (synopsis "R bindings for the plog C++ logging library")
    (description
     "This package provides the header files for a stripped-down version of
the plog header-only C++ logging library, and a method to log to R's standard
error stream.")
    (license license:expat)))

(define-public r-pls
  (package
    (name "r-pls")
    (version "2.7-2")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "pls" version))
       (sha256
        (base32 "121byimd6bg7jbrq5wz5fpi0vxq0vh8g724vkhnjzszbvcv1xsb7"))))
    (build-system r-build-system)
    (home-page "https://mevik.net/work/software/pls.html")
    (synopsis "Partial Least Squares and Principal Component Regression")
    (description
     "The pls package implements multivariate regression methods: Partial Least
Squares Regression (@dfn{PLSR}), Principal Component Regression (@dfn{PCR}), and
Canonical Powered Partial Least Squares (@dfn{CPPLS}).  It supports:

@itemize
@item several algorithms: the traditional orthogonal scores (@dfn{NIPALS}) PLS
algorithm, kernel PLS, wide kernel PLS, Simpls, and PCR through @code{svd}
@item multi-response models (or @dfn{PLS2})
@item flexible cross-validation
@item Jackknife variance estimates of regression coefficients
@item extensive and flexible plots: scores, loadings, predictions, coefficients,
(R)MSEP, R², and correlation loadings
@item formula interface, modelled after @code{lm()}, with methods for predict,
print, summary, plot, update, etc.
@item extraction functions for coefficients, scores, and loadings
@item MSEP, RMSEP, and R² estimates
@item multiplicative scatter correction (@dfn{MSC})
@end itemize\n")
    (license license:gpl2)))

(define-public r-ps
  (package
    (name "r-ps")
    (version "1.3.2")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "ps" version))
       (sha256
        (base32 "0127q6pw9iw8hhcfp231gmdh29nahh2n5jzc38avrzy7yrm4bwl9"))))
    (build-system r-build-system)
    (home-page "https://ps.r-lib.org")
    (synopsis "List, query, and manipulate system processes")
    (description
     "The ps package implements an API to list, query, and manipulate system
processes.  Most of its code is based on the @code{psutil} Python package.")
    (license license:bsd-3)))

(define-public r-pkgbuild
  (package
    (name "r-pkgbuild")
    (version "1.0.6")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "pkgbuild" version))
       (sha256
        (base32 "0xnlz6ivhkbmncg9hfw5p69lm4rjy3wn5lyxmygxyf4rrfnnqwxx"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-callr" ,r-callr)
       ("r-cli" ,r-cli)
       ("r-crayon" ,r-crayon)
       ("r-desc" ,r-desc)
       ("r-prettyunits" ,r-prettyunits)
       ("r-r6" ,r-r6)
       ("r-rprojroot" ,r-rprojroot)
       ("r-withr" ,r-withr)))
    (home-page "https://github.com/r-pkgs/pkgbuild")
    (synopsis "Find tools needed to build R packages")
    (description
     "This package provides functions used to build R packages.  It locates
compilers needed to build R packages on various platforms and ensures the PATH
is configured appropriately so R can use them.")
    (license license:gpl3)))

(define-public r-pkgload
  (package
    (name "r-pkgload")
    (version "1.0.2")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "pkgload" version))
       (sha256
        (base32
         "0z7jvharafahi2gv5547mk1n499isjzw06kfwymmxc0gd575d1ii"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-desc" ,r-desc)
       ("r-pkgbuild" ,r-pkgbuild)
       ("r-rlang" ,r-rlang)
       ("r-rprojroot" ,r-rprojroot)
       ("r-rstudioapi" ,r-rstudioapi)
       ("r-withr" ,r-withr)))
    (home-page "https://github.com/r-lib/pkgload")
    (synopsis "Simulate package installation and attach")
    (description
     "This package simulates the process of installing a package and then
attaching it.  This is a key part of the @code{devtools} package as it allows
you to rapidly iterate while developing a package.")
    (license license:gpl3)))

(define-public r-rcpp
  (package
    (name "r-rcpp")
    (version "1.0.4.6")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "Rcpp" version))
       (sha256
        (base32 "00mk23zmrqn1c4mk9d6csjcbnl12wd7yicjk2ikmw5dyvdfngbs5"))))
    (build-system r-build-system)
    (home-page "http://www.rcpp.org")
    (synopsis "Seamless R and C++ integration")
    (description
     "The Rcpp package provides R functions as well as C++ classes which offer
a seamless integration of R and C++.  Many R data types and objects can be
mapped back and forth to C++ equivalents which facilitates both writing of new
code as well as easier integration of third-party libraries.  Documentation
about Rcpp is provided by several vignettes included in this package, via the
@code{Rcpp Gallery} site at <http://gallery.rcpp.org>, the paper by Eddelbuettel
and Francois (2011, JSS), and the book by Eddelbuettel (2013, Springer); see
@code{citation(\"Rcpp\")} for details on these last two.")
    (license license:gpl2+)))

(define-public r-bindr
  (package
    (name "r-bindr")
    (version "0.1.1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "bindr" version))
       (sha256
        (base32
         "1l05fpk2yql3jka321c0bdgx6mqq9pvfrg2844lbjfpbgjkmqy3w"))))
    (build-system r-build-system)
    (home-page "https://github.com/krlmlr/bindr")
    (synopsis "Parametrized active bindings")
    (description
     "This package provides a simple interface for creating active bindings
where the bound function accepts additional arguments.")
    (license license:expat)))

(define-public r-bindrcpp
  (package
    (name "r-bindrcpp")
    (version "0.2.2")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "bindrcpp" version))
       (sha256
        (base32
         "0rz4ibjdjsxl99ff3ha79z7cnjmilx4rx58fk9kk7ld9xc4hf4s8"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-bindr" ,r-bindr)
       ("r-plogr" ,r-plogr)
       ("r-rcpp" ,r-rcpp)))
    (home-page "https://github.com/krlmlr/bindrcpp")
    (synopsis "Rcpp interface to active bindings")
    (description
     "This package provides an easy way to fill an environment with active
bindings that call a C++ function.")
    (license license:expat)))

(define-public r-auc
  (package
    (name "r-auc")
    (version "0.3.0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "AUC" version))
       (sha256
        (base32
         "0ripcib2qz0m7rgr1kiz68nx8f6p408l1ww7j78ljqik7p3g41g7"))))
    (properties `((upstream-name . "AUC")))
    (build-system r-build-system)
    (home-page "https://cran.r-project.org/web/packages/AUC")
    (synopsis "Compute the area under the curve of selected measures")
    (description
     "This package includes functions to compute the area under the curve of
selected measures: the area under the sensitivity curve (AUSEC), the area
under the specificity curve (AUSPC), the area under the accuracy
curve (AUACC), and the area under the receiver operating characteristic
curve (AUROC).  The curves can also be visualized.  Support for partial areas
is provided.")
    (license license:gpl2+)))

(define-public r-calibrate
  (package
    (name "r-calibrate")
    (version "1.7.5")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "calibrate" version))
       (sha256
        (base32 "1s423nr176l2sc66wp7hzgqkv7c2bq8d2bjrrvrrm5qa9y3zdx1k"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-mass" ,r-mass)))
    (home-page "https://cran.r-project.org/web/packages/calibrate")
    (synopsis "Calibration of scatterplot and biplot axes")
    (description
     "This is a package for drawing calibrated scales with tick marks
on (non-orthogonal) variable vectors in scatterplots and biplots.")
    (license license:gpl2)))

(define-public r-shape
  (package
    (name "r-shape")
    (version "1.4.4")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "shape" version))
       (sha256
        (base32
         "0hadk3mapkhbh8xjkiz52vxdagmmgvm15xwpzb90ikw4giyipjzl"))))
    (build-system r-build-system)
    (home-page "https://cran.r-project.org/web/packages/shape")
    (synopsis "Functions for plotting graphical shapes")
    (description
     "This package provides functions for plotting graphical shapes such as
ellipses, circles, cylinders, arrows, ...")
    (license license:gpl3+)))

(define-public r-globaloptions
  (package
    (name "r-globaloptions")
    (version "0.1.1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "GlobalOptions" version))
       (sha256
        (base32 "0x89hfz80avq4zcskxl71i4zi0mgniqqxfrvz050aa2189wfyja2"))))
    (properties `((upstream-name . "GlobalOptions")))
    (build-system r-build-system)
    (home-page "https://github.com/jokergoo/GlobalOptions")
    (synopsis "Generate functions to get or set global options")
    (description
     "This package provides more controls on the option values such as
validation and filtering on the values, making options invisible or private.")
    (license license:gpl2+)))

(define-public r-circlize
  (package
    (name "r-circlize")
    (version "0.4.8")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "circlize" version))
       (sha256
        (base32
         "0jvr9hmxyhg0zx101iiqkrg8wfaj86kp62xpv42n2j9fkn5r1mi2"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-colorspace" ,r-colorspace)
       ("r-globaloptions" ,r-globaloptions)
       ("r-shape" ,r-shape)))
    (home-page "https://github.com/jokergoo/circlize")
    (synopsis "Circular visualization")
    (description
     "Circular layout is an efficient way to visualise huge amounts of
information.  This package provides an implementation of circular layout
generation in R as well as an enhancement of available software.  Its
flexibility is based on the usage of low-level graphics functions such that
self-defined high-level graphics can be easily implemented by users for
specific purposes.  Together with the seamless connection between the powerful
computational and visual environment in R, it gives users more convenience and
freedom to design figures for better understanding complex patterns behind
multi-dimensional data.")
    (license license:gpl2+)))

(define-public r-powerlaw
  (package
    (name "r-powerlaw")
    (version "0.70.4")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "poweRlaw" version))
       (sha256
        (base32 "19zah9mx93az5lh9vicn3c8q1xb12g0w46dh5p901fbyimc32vwk"))))
    (properties `((upstream-name . "poweRlaw")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-vgam" ,r-vgam)))
    (home-page "https://github.com/csgillespie/poweRlaw")
    (synopsis "Tools for the analysis of heavy tailed distributions")
    (description
     "This package provides an implementation of maximum likelihood estimators
for a variety of heavy tailed distributions, including both the discrete and
continuous power law distributions.  Additionally, a goodness-of-fit based
approach is used to estimate the lower cut-off for the scaling region.")
    ;; Any of these GPL versions.
    (license (list license:gpl2 license:gpl3))))

(define-public r-compare
  (package
    (name "r-compare")
    (version "0.2-6")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "compare" version))
       (sha256
        (base32
         "0k9zms930b5dz9gy8414li21wy0zg9x9vp7301v5cvyfi0g7xzgw"))))
    (build-system r-build-system)
    (home-page "https://cran.r-project.org/web/packages/compare")
    (synopsis "Comparing objects for differences")
    (description
     "This package provides functions to compare a model object to a
comparison object.  If the objects are not identical, the functions can be
instructed to explore various modifications of the objects (e.g., sorting
rows, dropping names) to see if the modified versions are identical.")
    (license license:gpl2+)))

(define-public r-dendextend
  (package
    (name "r-dendextend")
    (version "1.13.4")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "dendextend" version))
       (sha256
        (base32
         "1pjbz6sb4pgh3d5pm53vmf3q8y6lq3hrgjd6547xxs3m63sb8mn4"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-ggplot2" ,r-ggplot2)
       ("r-magrittr" ,r-magrittr)
       ("r-viridis" ,r-viridis)))
    (home-page "https://cran.r-project.org/web/packages/dendextend")
    (synopsis "Extending 'dendrogram' functionality in R")
    (description
     "This package offers a set of functions for extending @code{dendrogram}
objects in R, letting you visualize and compare trees of hierarchical
clusterings.  You can adjust a tree's graphical parameters (the color, size,
type, etc of its branches, nodes and labels) and visually and statistically
compare different dendrograms to one another.")
    ;; Any of these versions
    (license (list license:gpl2 license:gpl3))))

(define-public r-getoptlong
  (package
    (name "r-getoptlong")
    (version "0.1.8")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "GetoptLong" version))
       (sha256
        (base32
         "1l8xkvyl152bsyvxazsvx2sm1vkygn75x0lsg3sbg7xp6drdn3kc"))))
    (properties `((upstream-name . "GetoptLong")))
    (build-system r-build-system)
    (inputs
     `(("perl" ,perl)))
    (propagated-inputs
     `(("r-globaloptions" ,r-globaloptions)
       ("r-rjson" ,r-rjson)))
    (home-page "https://github.com/jokergoo/GetoptLong")
    (synopsis "Parsing command-line arguments and variable interpolation")
    (description
     "This is yet another command-line argument parser which wraps the
powerful Perl module @code{Getopt::Long} and with some adaptation for easier
use in R.  It also provides a simple way for variable interpolation in R.")
    (license license:gpl2+)))

(define-public r-fastmatch
  (package
    (name "r-fastmatch")
    (version "1.1-0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "fastmatch" version))
       (sha256
        (base32
         "0z80jxkygmzn11sq0c2iz357s9bpki548lg926g85gldhfj1md90"))))
    (build-system r-build-system)
    (home-page "https://www.rforge.net/fastmatch")
    (synopsis "Fast match function")
    (description
     "This package provides a fast @code{match} replacement for cases that
require repeated look-ups.  It is slightly faster that R's built-in
@code{match} function on first match against a table, but extremely fast on
any subsequent lookup as it keeps the hash table in memory.")
    (license license:gpl2)))

(define-public r-ff
  (package
    (name "r-ff")
    (version "2.2-14")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "ff" version))
       (sha256
        (base32
         "1w724q4jpzbvzpilb2ifviaxkjgk9lzwxz9gksnvicbmfa20fqqw"))))
    (build-system r-build-system)
    (propagated-inputs `(("r-bit" ,r-bit)))
    (home-page "http://ff.r-forge.r-project.org/")
    (synopsis "Memory-efficient storage of large data on disk and access functions")
    (description
     "This package provides data structures that are stored on disk but
behave (almost) as if they were in RAM by transparently mapping only a section
in main memory.")
    ;; error Architecture not supported.
    (supported-systems (delete "aarch64-linux" %supported-systems))
    (license license:gpl2)))

(define-public r-ffbase
  (package
    (name "r-ffbase")
    (version "0.12.8")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "ffbase" version))
       (sha256
        (base32
         "0mjk7dkq1ginqqfvngzny747ggf9a8fd7kblq96n5ys1jrwjyqhq"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-bit" ,r-bit)
       ("r-fastmatch" ,r-fastmatch)
       ("r-ff" ,r-ff)))
    (home-page "http://github.com/edwindj/ffbase")
    (synopsis "Basic statistical functions for package 'ff'")
    (description
     "This package extends the out of memory vectors of @code{ff} with
statistical functions and other utilities to ease their usage.")
    (license license:gpl3)))

(define-public r-prettyunits
  (package
    (name "r-prettyunits")
    (version "1.1.1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "prettyunits" version))
       (sha256
        (base32
         "1ibmzgknw5896q2i6r59jz2izblxwgb29ivvjzx50pkd1jl9l6cs"))))
    (build-system r-build-system)
    (home-page "https://github.com/gaborcsardi/prettyunits")
    (synopsis "Pretty, human readable formatting of quantities")
    (description
     "This package provides tools for pretty, human readable formatting of
quantities.")
    (license license:expat)))

(define-public r-reshape
  (package
    (name "r-reshape")
    (version "0.8.8")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "reshape" version))
       (sha256
        (base32
         "0s6i0sqxg1vldxs6miv8mi0zydxbqzgpmzfiwkj8y7jix3yrfmad"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-plyr" ,r-plyr)
       ("r-rcpp" ,r-rcpp)))
    (home-page "http://had.co.nz/reshape")
    (synopsis "Flexibly reshape data")
    (description
     "Flexibly restructure and aggregate data using just two functions:
@code{melt} and @code{cast}.  This package provides them.")
    (license license:expat)))

(define-public r-progress
  (package
    (name "r-progress")
    (version "1.2.2")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "progress" version))
       (sha256
        (base32
         "0dgzb362641aqm8xd88iqa8jmpdm43xs0aba0d5kk6fvapnxi95l"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-crayon" ,r-crayon)
       ("r-hms" ,r-hms)
       ("r-prettyunits" ,r-prettyunits)
       ("r-r6" ,r-r6)))
    (home-page "https://github.com/gaborcsardi/progress")
    (synopsis "Terminal progress bars")
    (description
     "This package provides configurable progress bars.  They may include
percentage, elapsed time, and/or the estimated completion time.  They work in
terminals, in Emacs ESS, RStudio, Windows Rgui, and the macOS R.app.  The
package also provides a C++ API, that works with or without Rcpp.")
    (license license:expat)))

(define-public r-ggally
  (package
    (name "r-ggally")
    (version "1.5.0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "GGally" version))
       (sha256
        (base32
         "082s321zspg5al6acigwrhg4fsrmkkk5caabg662qbcy8v6n34h6"))))
    (properties `((upstream-name . "GGally")))
    (build-system r-build-system)
    (inputs
     `(("libressl" ,libressl)))
    (propagated-inputs
     `(("r-ggplot2" ,r-ggplot2)
       ("r-gtable" ,r-gtable)
       ("r-plyr" ,r-plyr)
       ("r-progress" ,r-progress)
       ("r-rcolorbrewer" ,r-rcolorbrewer)
       ("r-reshape" ,r-reshape)
       ("r-rlang" ,r-rlang)))
    (home-page "https://ggobi.github.io/ggally")
    (synopsis "Extension to ggplot2")
    (description
     "The R package ggplot2 is a plotting system based on the grammar of
graphics.  GGally extends ggplot2 by adding several functions to reduce the
complexity of combining geometric objects with transformed data.  Some of
these functions include a pairwise plot matrix, a two group pairwise plot
matrix, a parallel coordinates plot, a survival plot, and several functions to
plot networks.")
    (license license:gpl2+)))

(define-public r-proxy
  (package
    (name "r-proxy")
    (version "0.4-23")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "proxy" version))
       (sha256
        (base32
         "17b6qfllqrhzrxqgx7dccffgybnkcria5a68ap5ly3plg04ypm4x"))))
    (build-system r-build-system)
    (home-page "https://cran.r-project.org/web/packages/proxy")
    (synopsis "Distance and similarity measures")
    (description
     "This package provides an extensible framework for the efficient
calculation of auto- and cross-proximities, along with implementations of the
most popular ones.")
    (license license:gpl2)))

(define-public r-sp
  (package
    (name "r-sp")
    (version "1.4-1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "sp" version))
       (sha256
        (base32 "0fbh865r4py89g6ln8bslig2vbxxwa642p5k5g02rskyhajg35lg"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-lattice" ,r-lattice)))
    (home-page "https://cran.r-project.org/web/packages/sp")
    (synopsis "Classes and methods for spatial data")
    (description
     "This package provides classes and methods for spatial data; the classes
document where the spatial location information resides, for 2D or 3D data.
Utility functions are provided, e.g. for plotting data as maps, spatial
selection, as well as methods for retrieving coordinates, for subsetting,
print, summary, etc.")
    (license license:gpl2+)))

(define-public r-rmtstat
  (package
    (name "r-rmtstat")
    (version "0.3")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "RMTstat" version))
       (sha256
        (base32
         "1nn25q4kmh9kj975sxkrpa97vh5irqrlqhwsfinbck6h6ia4rsw1"))))
    (properties `((upstream-name . "RMTstat")))
    (build-system r-build-system)
    (home-page "https://cran.r-project.org/web/packages/RMTstat")
    (synopsis "Distributions, statistics and tests derived from random matrix theory")
    (description
     "This package provides functions for working with the Tracy-Widom laws
and other distributions related to the eigenvalues of large Wishart
matrices.")
    (license license:bsd-3)))

(define-public r-rmpi
  (package
    (name "r-rmpi")
    (version "0.6-9")
    (source (origin
              (method url-fetch)
              (uri (cran-uri "Rmpi" version))
              (sha256
               (base32
                "1rhycla98hxgnnxlxxldr1x51djak7c2jjvlrv3jcsvgwp1ymqdj"))))
    (properties `((upstream-name . "Rmpi")))
    (build-system r-build-system)
    (arguments
     `(#:configure-flags '("--configure-args=\"--with-Rmpi-type=OPENMPI\"")
       #:phases (modify-phases %standard-phases
                  (add-before 'install 'mpi-setup
                    ,%openmpi-setup))))
    (inputs
     `(("openmpi" ,openmpi)))
    (native-inputs
     `(("pkg-config" ,pkg-config)))
    (home-page "http://www.stats.uwo.ca/faculty/yu/Rmpi")
    (synopsis "R interface to message-passing interface (MPI)")
    (description
     "This package provides an interface (wrapper) to MPI APIs.  It also
provides an interactive R manager and worker environment.")
    (license license:gpl2+)))

(define-public r-lmoments
  (package
    (name "r-lmoments")
    (version "1.3-1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "Lmoments" version))
       (sha256
        (base32
         "0pc63bj9a8hzr5m3yssrc4kin39fffwkl8rggs3sagzr12d4i7bw"))))
    (properties `((upstream-name . "Lmoments")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-rcpp" ,r-rcpp)
       ("r-rcpparmadillo" ,r-rcpparmadillo)))
    (home-page "http://www.tilastotiede.fi/juha_karvanen.html")
    (synopsis "L-moments and quantile mixtures")
    (description
     "This package contains functions to estimate L-moments and trimmed
L-moments from the data.  It also contains functions to estimate the
parameters of the normal polynomial quantile mixture and the Cauchy polynomial
quantile mixture from L-moments and trimmed L-moments.")
    (license license:gpl2)))

(define-public r-distillery
  (package
    (name "r-distillery")
    (version "1.0-6")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "distillery" version))
       (sha256
        (base32
         "1mi3ig9jq0kd7yrwc5m37lmrw04p1b4lirnbsxi10z3n5yay4429"))))
    (build-system r-build-system)
    (home-page "https://ral.ucar.edu/staff/ericg/")
    (synopsis "Functions for confidence intervals and object information")
    (description
     "This package provides some very simple method functions for confidence
interval calculation and to distill pertinent information from a potentially
complex object; primarily used in common with the packages extRemes and
SpatialVx.")
    (license license:gpl2+)))

(define-public r-extremes
  (package
    (name "r-extremes")
    (version "2.0-11")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "extRemes" version))
       (sha256
        (base32
         "0hmgynxhzswqnhwb2sxrkczgam8c17s3vpxqc5bcz0bwczpxxyvm"))))
    (properties `((upstream-name . "extRemes")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-distillery" ,r-distillery)
       ("r-lmoments" ,r-lmoments)))
    (home-page "https://www.assessment.ucar.edu/toolkit/")
    (synopsis "Extreme value analysis")
    (description
     "ExtRemes is a suite of functions for carrying out analyses on the
extreme values of a process of interest; be they block maxima over long blocks
or excesses over a high threshold.")
    (license license:gpl2+)))

(define-public r-lmtest
  (package
    (name "r-lmtest")
    (version "0.9-37")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "lmtest" version))
       (sha256
        (base32
         "02nasm0j2vwkhz11dxqixs23msy1s3yj0jps6949fmgh9gwjkjfx"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-zoo" ,r-zoo)))
    (native-inputs
     `(("gfortran" ,gfortran)))
    (home-page "https://cran.r-project.org/web/packages/lmtest")
    (synopsis "Testing linear regression models")
    (description
     "This package provides a collection of tests, data sets, and examples for
diagnostic checking in linear regression models.  Furthermore, some generic
tools for inference in parametric models are provided.")
    ;; Either version is okay
    (license (list license:gpl2 license:gpl3))))

(define-public r-idr
  (package
    (name "r-idr")
    (version "1.2")
    (source (origin
              (method url-fetch)
              (uri (cran-uri "idr" version))
              (sha256
               (base32
                "05nvgw1xdg670bsjjrxkgd1mrdkciccpw4krn0zcgdf2r21dzgwb"))))
    (build-system r-build-system)
    (home-page "https://cran.r-project.org/web/packages/idr/")
    (synopsis "Irreproducible discovery rate")
    (description
     "This is a package for estimating the copula mixture model and plotting
correspondence curves in \"Measuring reproducibility of high-throughput
experiments\" (2011), Annals of Applied Statistics, Vol. 5, No. 3, 1752-1779,
by Li, Brown, Huang, and Bickel")
    (license license:gpl2+)))

(define-public r-inline
  (package
    (name "r-inline")
    (version "0.3.15")
    (source (origin
              (method url-fetch)
              (uri (cran-uri "inline" version))
              (sha256
               (base32
                "0s4wssvpan189fijahknxq5s22ww9bzmdlmyhnra748r7khky17z"))))
    (build-system r-build-system)
    (home-page "https://cran.r-project.org/web/packages/inline")
    (synopsis "Functions to inline C, C++, Fortran function calls from R")
    (description
     "This package provides functionality to dynamically define R functions
and S4 methods with inlined C, C++ or Fortran code supporting @code{.C} and
@code{.Call} calling conventions.")
    ;; Any version of the LGPL.
    (license license:lgpl3+)))

(define-public r-bdsmatrix
  (package
    (name "r-bdsmatrix")
    (version "1.3-4")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "bdsmatrix" version))
       (sha256
        (base32
         "1sh6pg43rgqvips4fx0k4vmp5i9lmniix0bqwj2yq5m06gs227i5"))))
    (properties `((upstream-name . "bdsmatrix")))
    (build-system r-build-system)
    (home-page "https://cran.r-project.org/web/packages/bdsmatrix/")
    (synopsis "Routines for block diagonal symmetric matrices")
    (description
     "This package provides procedures to work with block diagonal symmetric
matrices, a special case of sparse matrices.")
    (license license:lgpl2.0)))

(define-public r-bbmle
  (package
    (name "r-bbmle")
    (version "1.0.23.1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "bbmle" version))
       (sha256
        (base32
         "0p3l9shbr2846qmw8n0fyzf4j7gmi08aypl82jml3dwh26q1whk0"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-bdsmatrix" ,r-bdsmatrix)
       ("r-lattice" ,r-lattice)
       ("r-mass" ,r-mass)
       ("r-matrix" ,r-matrix)
       ("r-mvtnorm" ,r-mvtnorm)
       ("r-numderiv" ,r-numderiv)))
    (home-page "https://cran.r-project.org/web/packages/bbmle")
    (synopsis "Tools for General Maximum Likelihood Estimation")
    (description
     "This package provides methods and functions for fitting maximum
likelihood models in R.  This package modifies and extends the @code{mle}
classes in the @code{stats4} package.")
    ;; Any version of the GPL
    (license license:gpl2+)))

(define-public r-emdbook
  (package
    (name "r-emdbook")
    (version "1.3.12")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "emdbook" version))
       (sha256
        (base32
         "0ls3zxxlwmdv7zn1v9i1y9zc2sn0hbgmyjvsj7zn3ajsw7wwlih6"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-bbmle" ,r-bbmle)
       ("r-coda" ,r-coda)
       ("r-lattice" ,r-lattice)
       ("r-mass" ,r-mass)
       ("r-plyr" ,r-plyr)))
    (home-page "http://www.math.mcmaster.ca/bolker/emdbook")
    (synopsis "Support functions and data for \"Ecological Models and Data\"")
    (description
     "This package provides auxiliary functions and data sets for \"Ecological
Models and Data\", a book presenting maximum likelihood estimation and related
topics for ecologists (ISBN 978-0-691-12522-0).")
    ;; Any GPL version
    (license (list license:gpl2 license:gpl3))))

(define-public r-lpsolve
  (package
    (name "r-lpsolve")
    (version "5.6.15")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "lpSolve" version))
       (sha256
        (base32
         "1fpkyjyqykwa1dxnhiky01pm09syxg169lm7hpy39bdbg10vw9s6"))))
    (properties `((upstream-name . "lpSolve")))
    (build-system r-build-system)
    (home-page "https://cran.r-project.org/web/packages/lpSolve")
    (synopsis "R interface to Lp_solve to solve linear/integer programs")
    (description
     "Lp_solve is software for solving linear, integer and mixed integer
programs.  This implementation supplies a \"wrapper\" function in C and some R
functions that solve general linear/integer problems, assignment problems, and
transportation problems.")
    (license license:lgpl2.0)))

(define-public r-limsolve
  (package
    (name "r-limsolve")
    (version "1.5.6")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "limSolve" version))
       (sha256
        (base32
         "1829rd2cnd8qj80z9a7sgc7gx4sf3kvl5g6d2a0lqqw30f9sjzmr"))))
    (properties `((upstream-name . "limSolve")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-lpsolve" ,r-lpsolve)
       ("r-mass" ,r-mass)
       ("r-quadprog" ,r-quadprog)))
    (native-inputs `(("gfortran" ,gfortran)))
    (home-page "https://cran.r-project.org/web/packages/limSolve")
    (synopsis "Solving linear inverse models")
    (description
     "This package provides functions that:

@enumerate
@item find the minimum/maximum of a linear or quadratic function,
@item sample an underdetermined or overdetermined system,
@item solve a linear system Ax=B for the unknown x.
@end enumerate

It includes banded and tridiagonal linear systems.  The package calls Fortran
functions from LINPACK.")
    ;; Any GPL version.
    (license (list license:gpl2+ license:gpl3+))))

(define-public r-fitdistrplus
  (package
    (name "r-fitdistrplus")
    (version "1.0-14")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "fitdistrplus" version))
       (sha256
        (base32
         "10q08wsv8v3w7797jdvvv60bgrf1bi6438wf0jcqv81ays82a245"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-mass" ,r-mass)
       ("r-npsurv" ,r-npsurv)
       ("r-survival" ,r-survival)))
    (home-page "http://riskassessment.r-forge.r-project.org")
    (synopsis "Fitting a parametric distribution from data")
    (description
     "This package extends the @code{fitdistr} function of the MASS package
with several functions to help the fit of a parametric distribution to
non-censored or censored data.  Censored data may contain left-censored,
right-censored and interval-censored values, with several lower and upper
bounds.  In addition to @dfn{maximum likelihood estimation} (MLE), the package
provides moment matching (MME), quantile matching (QME) and maximum
goodness-of-fit estimation (MGE) methods (available only for non-censored
data).  Weighted versions of MLE, MME and QME are available.")
    (license license:gpl2+)))

(define-public r-energy
  (package
    (name "r-energy")
    (version "1.7-7")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "energy" version))
       (sha256
        (base32
         "13wnx5nwk7nsv7vf5sxhz4y0rxrnzm76ldgywk1bxrz67srqzf37"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-boot" ,r-boot)
       ("r-rcpp" ,r-rcpp)))
    (home-page "https://cran.r-project.org/web/packages/energy")
    (synopsis "Multivariate inference via the energy of data")
    (description
     "This package provides e-statistics (energy) tests and statistics for
multivariate and univariate inference, including distance correlation,
one-sample, two-sample, and multi-sample tests for comparing multivariate
distributions, are implemented.  Measuring and testing multivariate
independence based on distance correlation, partial distance correlation,
multivariate goodness-of-fit tests, clustering based on energy distance,
testing for multivariate normality, distance components (disco) for
non-parametric analysis of structured data, and other energy
statistics/methods are implemented.")
    (license license:gpl2+)))

(define-public r-suppdists
  (package
    (name "r-suppdists")
    (version "1.1-9.5")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "SuppDists" version))
       (sha256
        (base32
         "01j6p94m1g363nph2158fq2rmd6z3h5dvcv6aidh2d6syw131xak"))))
    (properties `((upstream-name . "SuppDists")))
    (build-system r-build-system)
    (home-page "https://cran.r-project.org/web/packages/SuppDists")
    (synopsis "Supplementary distributions")
    (description
     "This package provides ten distributions supplementing those built into
R.  Inverse Gauss, Kruskal-Wallis, Kendall's Tau, Friedman's chi squared,
Spearman's rho, maximum F ratio, the Pearson product moment correlation
coefficient, Johnson distributions, normal scores and generalized
hypergeometric distributions.  In addition two random number generators of
George Marsaglia are included.")
    (license license:gpl2+)))

(define-public r-ksamples
  (package
    (name "r-ksamples")
    (version "1.2-9")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "kSamples" version))
       (sha256
        (base32
         "1zs22p68d6320kcylisnk0b5wmpapxkyz15py09czxzw7npw8gms"))))
    (properties `((upstream-name . "kSamples")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-suppdists" ,r-suppdists)))
    (home-page "https://cran.r-project.org/web/packages/kSamples")
    (synopsis "K-Sample rank tests and their combinations")
    (description
     "This package provides tools to compares k samples using the
Anderson-Darling test, Kruskal-Wallis type tests with different rank score
criteria, Steel's multiple comparison test, and the Jonckheere-Terpstra (JT)
test.  It computes asymptotic, simulated or (limited) exact P-values, all
valid under randomization, with or without ties, or conditionally under random
sampling from populations, given the observed tie pattern.  Except for Steel's
test and the JT test it also combines these tests across several blocks of
samples.")
    (license license:gpl2+)))

(define-public r-cvst
  (package
    (name "r-cvst")
    (version "0.2-2")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "CVST" version))
       (sha256
        (base32
         "05l3yzkfrbds09ah9cdwn2sn4ryhq78lz33ryzrgkv176jc8qjw5"))))
    (properties `((upstream-name . "CVST")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-kernlab" ,r-kernlab)
       ("r-matrix" ,r-matrix)))
    (home-page "https://cran.r-project.org/web/packages/CVST")
    (synopsis "Fast cross-validation via sequential testing")
    (description
     "This package implements the fast cross-validation via sequential
testing (CVST) procedure.  CVST is an improved cross-validation procedure
which uses non-parametric testing coupled with sequential analysis to
determine the best parameter set on linearly increasing subsets of the data.
Additionally to the CVST the package contains an implementation of the
ordinary k-fold cross-validation with a flexible and powerful set of helper
objects and methods to handle the overall model selection process.  The
implementations of the Cochran's Q test with permutations and the sequential
testing framework of Wald are generic and can therefore also be used in other
contexts.")
    (license license:gpl2+)))

(define-public r-squarem
  (package
    (name "r-squarem")
    (version "2020.2")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "SQUAREM" version))
       (sha256
        (base32
         "1j6sa93xjvynnzx9jx79a3fysbykmbqyknknsqif5bcha6xp6cvf"))))
    (properties `((upstream-name . "SQUAREM")))
    (build-system r-build-system)
    (home-page "https://coah.jhu.edu/people/Faculty_personal_Pages/Varadhan.html")
    (synopsis "Squared Extrapolation Methods for Accelerating EM-Like Monotone Algorithms")
    (description
     "This package provides algorithms for accelerating the convergence of
slow, monotone sequences from smooth, contraction mapping such as the EM
algorithm.  It can be used to accelerate any smooth, linearly convergent
acceleration scheme.  A tutorial style introduction to this package is
available in a vignette.")
    (license license:gpl2+)))

(define-public r-lava
  (package
    (name "r-lava")
    (version "1.6.7")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "lava" version))
       (sha256
        (base32
         "0ffzxbb8pvfh1m6j61az4ga37snyhylq2941fyc76w7w9i2sixv3"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-numderiv" ,r-numderiv)
       ("r-squarem" ,r-squarem)
       ("r-survival" ,r-survival)))
    (home-page "https://github.com/kkholst/lava")
    (synopsis "Latent variable models")
    (description
     "This package provides tools for the estimation and simulation of latent
variable models.")
    (license license:gpl3)))

(define-public r-drr
  (package
    (name "r-drr")
    (version "0.0.4")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "DRR" version))
       (sha256
        (base32
         "1y70si1gig4l7jx5jiqsqliyywfsvimkx53x3zh1lc3yj2j6bqwk"))))
    (properties `((upstream-name . "DRR")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-cvst" ,r-cvst)
       ("r-kernlab" ,r-kernlab)
       ("r-matrix" ,r-matrix)))
    (home-page "https://cran.r-project.org/web/packages/DRR")
    (synopsis "Dimensionality reduction via regression")
    (description
     "This package provides an implementation of dimensionality reduction via
regression using Kernel Ridge Regression.")
    (license license:gpl3)))

(define-public r-prodlim
  (package
    (name "r-prodlim")
    (version "2019.11.13")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "prodlim" version))
       (sha256
        (base32
         "03wvh3kirp1prac5nky6a5whs97rvaf4hc27x0fnh51sa17r42b8"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-kernsmooth" ,r-kernsmooth)
       ("r-lava" ,r-lava)
       ("r-rcpp" ,r-rcpp)
       ("r-survival" ,r-survival)))
    (home-page "https://cran.r-project.org/web/packages/prodlim")
    (synopsis "Product-limit estimation for censored event history analysis")
    (description
     "This package provides a fast and user-friendly implementation of
nonparametric estimators for censored event history (survival) analysis with
the Kaplan-Meier and Aalen-Johansen methods.")
    (license license:gpl2+)))

(define-public r-dimred
  (package
    (name "r-dimred")
    (version "0.2.3")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "dimRed" version))
       (sha256
        (base32
         "110d6y83ib1nfpxzmvkvb3fn3brskwkdbsk4dqrdrswrd4znxrg6"))))
    (properties `((upstream-name . "dimRed")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-drr" ,r-drr)
       ("r-magrittr" ,r-magrittr)))
    (home-page "https://github.com/gdkrmr/dimRed")
    (synopsis "Framework for dimensionality reduction")
    (description
     "This package provides a collection of dimensionality reduction
techniques from R packages and provides a common interface for calling the
methods.")
    (license license:gpl3)))

(define-public r-timedate
  (package
    (name "r-timedate")
    (version "3043.102")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "timeDate" version))
       (sha256
        (base32
         "0wvl5pq261rvbgly7vilk3x3m9xk3ly6il1i5scwdf6srl1vlz1p"))))
    (properties `((upstream-name . "timeDate")))
    (build-system r-build-system)
    (home-page "https://www.rmetrics.org")
    (synopsis "Chronological and calendar objects")
    (description
     "This package provides an environment for teaching \"Financial
Engineering and Computational Finance\" and for managing chronological and
calendar objects.")
    (license license:gpl2+)))

(define-public r-magic
  (package
    (name "r-magic")
    (version "1.5-9")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "magic" version))
       (sha256
        (base32
         "0snmdh6vk0p6ar1swsihisinxrx7l8371dri5lk0z24ysgr5w7gs"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-abind" ,r-abind)))
    (home-page "https://github.com/RobinHankin/magic.git")
    (synopsis "Create and investigate magic squares")
    (description
     "This package provides a collection of efficient, vectorized algorithms
for the creation and investigation of magic squares and hypercubes, including
a variety of functions for the manipulation and analysis of arbitrarily
dimensioned arrays.")
    (license license:gpl2)))

(define-public r-rmysql
  (package
    (name "r-rmysql")
    (version "0.10.20")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "RMySQL" version))
       (sha256
        (base32
         "0lv9m6zpm8dgv7yixr6xhw379vbq45d7n7gkrmjrppdj8vcih77i"))))
    (properties `((upstream-name . "RMySQL")))
    (build-system r-build-system)
    (inputs
     `(("mariadb" ,mariadb "lib")
       ("mariadb-dev" ,mariadb "dev")
       ("zlib" ,zlib)))
    (propagated-inputs
     `(("r-dbi" ,r-dbi)))
    (home-page "https://github.com/r-dbi/RMySQL")
    (synopsis "Database interface and MySQL driver for R")
    (description
     "This package provides a DBI interface to MySQL / MariaDB.  The RMySQL
package contains an old implementation based on legacy code from S-PLUS which
is being phased out.  A modern MySQL client based on Rcpp is available from
the RMariaDB package.")
    (license license:gpl2)))

(define-public r-rpostgresql
  (package
    (name "r-rpostgresql")
    (version "0.6-2")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "RPostgreSQL" version))
       (sha256
        (base32
         "1mdhw5821v2h7hpa53v10wz53k4i90r0vb6a3dia5gq8f9j1h088"))))
    (properties `((upstream-name . "RPostgreSQL")))
    (build-system r-build-system)
    (inputs
     `(("postgresql" ,postgresql)))
    (propagated-inputs
     `(("r-dbi" ,r-dbi)))
    (home-page "https://github.com/tomoakin/RPostgreSQL")
    (synopsis "R interface to the PostgreSQL database system")
    (description
     "This package provides a Database Interface (DBI) compliant driver for R
to access PostgreSQL database systems.")
    ;; The whole package is released under GPL version 2.  It includes code
    ;; under the PostgreSQL license.
    (license license:gpl2)))

(define-public r-linprog
  (package
    (name "r-linprog")
    (version "0.9-2")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "linprog" version))
       (sha256
        (base32
         "1ki14an0pmhs2mnmfjjvdzd76pshiyvi659zf7hqvqwj0viv4dw9"))))
    (build-system r-build-system)
    (propagated-inputs `(("r-lpsolve" ,r-lpsolve)))
    (home-page "http://linprog.r-forge.r-project.org/")
    (synopsis "Linear programming and optimization")
    (description
     "This package can be used to solve Linear Programming / Linear
Optimization problems by using the simplex algorithm.")
    (license license:gpl2+)))

(define-public r-geometry
  (package
    (name "r-geometry")
    (version "0.4.5")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "geometry" version))
       (sha256
        (base32
         "1n10l8ax3783v3lgaacb15qsn8b3f0wpmhg3k39j31s6ciyd3vcg"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-magic" ,r-magic)
       ("r-linprog" ,r-linprog)
       ("r-lpsolve" ,r-lpsolve)
       ("r-rcpp" ,r-rcpp)
       ("r-rcppprogress" ,r-rcppprogress)))
    (home-page "http://geometry.r-forge.r-project.org/")
    (synopsis "Mesh generation and surface tesselation")
    (description
     "This package makes the qhull library available in R, in a similar manner
as in Octave.  Qhull computes convex hulls, Delaunay triangulations, halfspace
intersections about a point, Voronoi diagrams, furthest-site Delaunay
triangulations, and furthest-site Voronoi diagrams.  It runs in 2-d, 3-d, 4-d,
and higher dimensions.  It implements the Quickhull algorithm for computing
the convex hull.  Qhull does not support constrained Delaunay triangulations,
or mesh generation of non-convex objects, but the package does include some R
functions that allow for this.  Currently the package only gives access to
Delaunay triangulation and convex hull computation.")
    ;; The Qhull sources are included and are distributed under a custom
    ;; non-copyleft license.  The R sources are released under GPL version 2.
    (license (list license:gpl2
                   (license:non-copyleft "http://www.qhull.org/COPYING.txt")))))

(define-public r-ddalpha
  (package
    (name "r-ddalpha")
    (version "1.3.11")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "ddalpha" version))
       (sha256
        (base32
         "1sdnb47r534nh138zk3a6b2mgi74nvshc7p5m304vjs9jlx4l2y3"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-bh" ,r-bh)
       ("r-class" ,r-class)
       ("r-geometry" ,r-geometry)
       ("r-mass" ,r-mass)
       ("r-rcpp" ,r-rcpp)
       ("r-robustbase" ,r-robustbase)
       ("r-sfsmisc" ,r-sfsmisc)))
    (native-inputs
     `(("gfortran" ,gfortran)))
    (home-page "https://cran.r-project.org/web/packages/ddalpha")
    (synopsis "Depth-Based classification and calculation of data depth")
    (description
     "This package contains procedures for depth-based supervised learning,
which are entirely non-parametric, in particular the DDalpha-procedure (Lange,
Mosler and Mozharovskyi, 2014).  The training data sample is transformed by a
statistical depth function to a compact low-dimensional space, where the final
classification is done.  It also offers an extension to functional data and
routines for calculating certain notions of statistical depth functions.  50
multivariate and 5 functional classification problems are included.")
    (license license:gpl2)))

(define-public r-gower
  (package
    (name "r-gower")
    (version "0.2.1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "gower" version))
       (sha256
        (base32
         "007ivwn1nagpi26qq8iih1c2l61c53glvv60n90hi341ry8vwgxg"))))
    (build-system r-build-system)
    (home-page "https://github.com/markvanderloo/gower")
    (synopsis "Gower's distance")
    (description
     "This package provides tools to compute Gower's distance (or similarity)
coefficient between records, and to compute the top-n matches between records.
Core algorithms are executed in parallel on systems supporting OpenMP.")
    (license license:gpl3)))

(define-public r-rcpproll
  (package
    (name "r-rcpproll")
    (version "0.3.0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "RcppRoll" version))
       (sha256
        (base32
         "0srzfhzkk42kzrdjnhbb37946jp1p688rgysy6k3i2is8jb21zyb"))))
    (properties `((upstream-name . "RcppRoll")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-rcpp" ,r-rcpp)))
    (home-page "https://cran.r-project.org/web/packages/RcppRoll")
    (synopsis "Efficient rolling and windowed operations")
    (description
     "This package provides fast and efficient routines for common rolling /
windowed operations.  Routines for the efficient computation of windowed mean,
median, sum, product, minimum, maximum, standard deviation and variance are
provided.")
    (license license:gpl2+)))

(define-public r-ipred
  (package
    (name "r-ipred")
    (version "0.9-9")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "ipred" version))
       (sha256
        (base32
         "0vs1hqfx7yd0xdbmfsf2gim7spkni0845cj6gswn0nhdfdq7ma0d"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-class" ,r-class)
       ("r-mass" ,r-mass)
       ("r-nnet" ,r-nnet)
       ("r-prodlim" ,r-prodlim)
       ("r-rpart" ,r-rpart)
       ("r-survival" ,r-survival)))
    (home-page "https://cran.r-project.org/web/packages/ipred")
    (synopsis "Improved predictors")
    (description
     "This package provides improved predictive models by indirect
classification and bagging for classification, regression and survival
problems as well as resampling based estimators of prediction error.")
    (license license:gpl2+)))

(define-public r-psych
  (package
    (name "r-psych")
    (version "1.9.12.31")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "psych" version))
       (sha256
        (base32
         "02i9p6appf15hjdsi58g39bzs9as40f9qhy8m7ki30hd1fz1vrr5"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-lattice" ,r-lattice)
       ("r-mnormt" ,r-mnormt)
       ("r-nlme" ,r-nlme)))
    (home-page "https://cran.r-project.org/web/packages/psych/")
    (synopsis "Procedures for psychological, psychometric, and personality research")
    (description
     "This package provides a general purpose toolbox for personality,
psychometric theory and experimental psychology.  Functions are primarily for
multivariate analysis and scale construction using factor analysis, principal
component analysis, cluster analysis and reliability analysis, although others
provide basic descriptive statistics.  Item Response Theory is done using
factor analysis of tetrachoric and polychoric correlations.  Functions for
analyzing data at multiple levels include within and between group statistics,
including correlations and factor analysis.  Functions for simulating and
testing particular item and test structures are included.  Several functions
serve as a useful front end for structural equation modeling.  Graphical
displays of path diagrams, factor analysis and structural equation models are
created using basic graphics.")
    (license license:gpl2+)))

(define-public r-generics
  (package
    (name "r-generics")
    (version "0.0.2")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "generics" version))
       (sha256
        (base32
         "0xk1xhpy7gpv3pvaygzhpfdxj72zmb38pb4nscfyg2ff36vx3cvi"))))
    (build-system r-build-system)
    (home-page "https://github.com/r-lib/generics")
    (synopsis "Common S3 generics not provided by base R methods")
    (description
     "In order to reduce potential package dependencies and conflicts,
generics provides a number of commonly used S3 generics that are not provided
by base R methods related to model fitting.")
    (license license:gpl2)))

(define-public r-broom
  (package
    (name "r-broom")
    (version "0.5.5")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "broom" version))
       (sha256
        (base32
         "0n7zd64263kfavdi28rl2bxrsa00c3m4vjhhjdrfwvvmrcxj39fx"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-backports" ,r-backports)
       ("r-dplyr" ,r-dplyr)
       ("r-generics" ,r-generics)
       ("r-nlme" ,r-nlme)
       ("r-purrr" ,r-purrr)
       ("r-reshape2" ,r-reshape2)
       ("r-stringr" ,r-stringr)
       ("r-tibble" ,r-tibble)
       ("r-tidyr" ,r-tidyr)))
    (home-page "https://github.com/tidyverse/broom")
    (synopsis "Convert statistical analysis objects into tidy data frames")
    (description
     "This package provides tools to convert statistical analysis objects from
R into tidy data frames, so that they can more easily be combined, reshaped
and otherwise processed with tools like @code{dplyr}, @code{tidyr} and
@code{ggplot2}.  The package provides three S3 generics: @code{tidy}, which
summarizes a model's statistical findings such as coefficients of a
regression; @code{augment}, which adds columns to the original data such as
predictions, residuals and cluster assignments; and @code{glance}, which
provides a one-row summary of model-level statistics.")
    (license license:expat)))

(define-public r-recipes
  (package
    (name "r-recipes")
    (version "0.1.10")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "recipes" version))
       (sha256
        (base32
         "11f96aanrzi2v6cn49fhvf9y4cmhra63wcy6nvpv6hcfaqqmwd2g"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-dplyr" ,r-dplyr)
       ("r-generics" ,r-generics)
       ("r-glue" ,r-glue)
       ("r-gower" ,r-gower)
       ("r-ipred" ,r-ipred)
       ("r-lubridate" ,r-lubridate)
       ("r-magrittr" ,r-magrittr)
       ("r-matrix" ,r-matrix)
       ("r-purrr" ,r-purrr)
       ("r-rlang" ,r-rlang)
       ("r-tibble" ,r-tibble)
       ("r-tidyr" ,r-tidyr)
       ("r-tidyselect" ,r-tidyselect)
       ("r-timedate" ,r-timedate)
       ("r-withr" ,r-withr)))
    (native-inputs
     `(("r-knitr" ,r-knitr)))
    (home-page "https://github.com/topepo/recipes")
    (synopsis "Preprocessing tools to create design matrices")
    (description
     "Recipes is an extensible framework to create and preprocess design
matrices.  Recipes consist of one or more data manipulation and analysis
\"steps\".  Statistical parameters for the steps can be estimated from an
initial data set and then applied to other data sets.  The resulting design
matrices can then be used as inputs into statistical or machine learning
models.")
    (license license:gpl2)))

(define-public r-pdist
  (package
    (name "r-pdist")
    (version "1.2")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "pdist" version))
       (sha256
        (base32
         "18nd3mgad11f2zmwcp0w3sxlch4a9y6wp8dfdyzvjn7y4b4bq0dd"))))
    (build-system r-build-system)
    (home-page "https://github.com/jeffwong/pdist")
    (synopsis "Partitioned distance function")
    (description
     "Pdist computes the euclidean distance between rows of a matrix X and
rows of another matrix Y.  Previously, this could be done by binding the two
matrices together and calling @code{dist}, but this creates unnecessary
computation by computing the distances between a row of X and another row of
X, and likewise for Y.  Pdist strictly computes distances across the two
matrices, not within the same matrix, making computations significantly faster
for certain use cases.")
    (license license:gpl3+)))

(define-public r-ggrepel
  (package
    (name "r-ggrepel")
    (version "0.8.2")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "ggrepel" version))
       (sha256
        (base32
         "1qaifn3dazdqbqlii210xhw7yf142iw7g9p2axmmxbz90p0by08d"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-ggplot2" ,r-ggplot2)
       ("r-rcpp" ,r-rcpp)
       ("r-scales" ,r-scales)))
    (native-inputs
     `(("r-knitr" ,r-knitr))) ; for vignettes
    (home-page "http://github.com/slowkow/ggrepel")
    (synopsis "Repulsive text and label geometries for ggplot2")
    (description
     "This package provides text and label geometries for ggplot2 that help to
avoid overlapping text labels.  Labels repel away from each other and away
from the data points.")
    (license license:gpl3)))

(define-public r-corrplot
  (package
    (name "r-corrplot")
    (version "0.84")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "corrplot" version))
       (sha256
        (base32
         "1k03qd8db7pwg1v318xapx5mpiypiz2n07qr19c4b45diri5xkhd"))))
    (build-system r-build-system)
    (home-page "https://github.com/taiyun/corrplot")
    (synopsis "Visualization of a correlation matrix")
    (description
     "This package provides a graphical display of a correlation matrix or
general matrix.  It also contains some algorithms to do matrix reordering.  In
addition, corrplot is good at details, including choosing color, text labels,
color labels, layout, etc.")
    ;; Any version of the GPL
    (license license:gpl2+)))

(define-public r-stringdist
  (package
    (name "r-stringdist")
    (version "0.9.5.5")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "stringdist" version))
       (sha256
        (base32 "1dqfakclzaf878x7mhwmqrcpcql2h9cv19fz5f3ygpajf3si5kqi"))))
    (build-system r-build-system)
    (home-page "https://github.com/markvanderloo/stringdist")
    (synopsis "Approximate string matching and string distance functions")
    (description
     "This package implements an approximate string matching version of R's
native @code{match} function.  It can calculate various string distances based
on edits (Damerau-Levenshtein, Hamming, Levenshtein, optimal sting alignment),
qgrams (q- gram, cosine, jaccard distance) or heuristic metrics (Jaro,
Jaro-Winkler).  An implementation of soundex is provided as well.  Distances
can be computed between character vectors while taking proper care of encoding
or between integer vectors representing generic sequences.")
    (license license:gpl3+)))

(define-public r-ucminf
  (package
    (name "r-ucminf")
    (version "1.1-4")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "ucminf" version))
       (sha256
        (base32
         "01vggwg1w71k98qs6fhb0x1843vi322mf4g3hbclks94kcpkisx2"))))
    (build-system r-build-system)
    (native-inputs `(("gfortran" ,gfortran)))
    (home-page "https://cran.r-project.org/web/packages/ucminf/")
    (synopsis "General-purpose unconstrained non-linear optimization")
    (description
     "This package provides an implementation of an algorithm for
general-purpose unconstrained non-linear optimization.  The algorithm is of
quasi-Newton type with BFGS updating of the inverse Hessian and soft line
search with a trust region type monitoring of the input to the line search
algorithm.  The interface of @code{ucminf} is designed for easy interchange
with the package @code{optim}.")
    (license license:gpl2+)))

(define-public r-ordinal
  (package
    (name "r-ordinal")
    (version "2019.12-10")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "ordinal" version))
       (sha256
        (base32
         "09bpmjmbf4x82kgf6bm4bkncq2apdv9mk20zj4zgma2jx2vyfhbs"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-mass" ,r-mass)
       ("r-matrix" ,r-matrix)
       ("r-numderiv" ,r-numderiv)
       ("r-ucminf" ,r-ucminf)))
    (home-page "https://github.com/runehaubo/ordinal")
    (synopsis "Regression models for ordinal data")
    (description
     "This package provides an implementation of cumulative link (mixed)
models also known as ordered regression models, proportional odds models,
proportional hazards models for grouped survival times and ordered models.
Estimation is via maximum likelihood and mixed models are fitted with the
Laplace approximation and adaptive Gauss-Hermite quadrature.")
    (license license:gpl2+)))

(define-public r-jomo
  (package
    (name "r-jomo")
    (version "2.6-10")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "jomo" version))
       (sha256
        (base32
         "1k9l4290g350zbw1pjs871q9bxj3j2h1dilxpp06v4wy4n7d8qs0"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-lme4" ,r-lme4)
       ("r-mass" ,r-mass)
       ("r-ordinal" ,r-ordinal)
       ("r-survival" ,r-survival)))
    (home-page "https://cran.r-project.org/web/packages/jomo/")
    (synopsis "Multilevel Joint Modelling Multiple Imputation")
    (description
     "Similarly to Schafer's package pan, jomo is a package for multilevel
joint modelling multiple imputation @url{Carpenter and Kenward (2013),
http://doi.org/10.1002/9781119942283}.  Novel aspects of jomo are the
possibility of handling binary and categorical data through latent normal
variables, the option to use cluster-specific covariance matrices and to
impute compatibly with the substantive model.")
    (license license:gpl2)))

(define-public r-pan
  (package
    (name "r-pan")
    (version "1.6")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "pan" version))
       (sha256
        (base32
         "1dk3jjj826p7xrz10qz04vyc068xnypg7bp0pj4c32z3da0xzh5d"))))
    (build-system r-build-system)
    (native-inputs `(("gfortran" ,gfortran)))
    (home-page "https://cran.r-project.org/web/packages/pan/")
    (synopsis "Multiple imputation for multivariate panel or clustered data")
    (description
     "This package implements multiple imputation for multivariate panel or
clustered data.")
    (license license:gpl3)))

(define-public r-mitml
  (package
    (name "r-mitml")
    (version "0.3-7")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "mitml" version))
       (sha256
        (base32
         "0yqyxkyi1kmv5k63wxj5kkg5g8igk1axk2csb4xhj6wz0p89dxy6"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-haven" ,r-haven)
       ("r-jomo" ,r-jomo)
       ("r-pan" ,r-pan)))
    (home-page "https://cran.r-project.org/web/packages/mitml/")
    (synopsis "Tools for multiple imputation in multilevel modeling")
    (description
     "This package provides tools for multiple imputation of missing data in
multilevel modeling.  It includes a user-friendly interface to the packages
pan and jomo, and several functions for visualization, data management and the
analysis of multiply imputed data sets.")
    (license license:gpl2+)))

(define-public r-mice
  (package
    (name "r-mice")
    (version "3.8.0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "mice" version))
       (sha256
        (base32
         "1ibybvigqkkla4xwhqs2w4m6c68alfcdsljx99nn4p92rzb1ig04"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-broom" ,r-broom)
       ("r-dplyr" ,r-dplyr)
       ("r-lattice" ,r-lattice)
       ("r-rcpp" ,r-rcpp)
       ("r-tidyr" ,r-tidyr)))
    (home-page "https://cran.r-project.org/web/packages/mice/")
    (synopsis "Multivariate imputation by chained equations")
    (description
     "Multiple imputation using @dfn{Fully Conditional Specification} (FCS)
implemented by the MICE algorithm as described in @url{Van Buuren and
Groothuis-Oudshoorn (2011), http://doi.org/10.18637/jss.v045.i03}.  Each
variable has its own imputation model.  Built-in imputation models are
provided for continuous data (predictive mean matching, normal), binary
data (logistic regression), unordered categorical data (polytomous logistic
regression) and ordered categorical data (proportional odds).  MICE can also
impute continuous two-level data (normal model, pan, second-level variables).
Passive imputation can be used to maintain consistency between variables.
Various diagnostic plots are available to inspect the quality of the
imputations.")
    ;; Any of these two versions.
    (license (list license:gpl2 license:gpl3))))

(define-public r-truncnorm
  (package
    (name "r-truncnorm")
    (version "1.0-8")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "truncnorm" version))
       (sha256
        (base32
         "0zn88wdd58223kibk085rhsikl4yhlrwiyq109hzjg06hy6lwmj9"))))
    (build-system r-build-system)
    (home-page "https://cran.r-project.org/web/packages/truncnorm/")
    (synopsis "Truncated normal distribution")
    (description "This package provides functions for the truncated normal
distribution with mean equal to @code{mean} and standard deviation equal to
@code{sd}.  It includes density, distribution, quantile, and expected value
functions, as well as a random generation function.")
    (license license:gpl2)))

(define-public r-rsolnp
  (package
    (name "r-rsolnp")
    (version "1.16")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "Rsolnp" version))
       (sha256
        (base32
         "0w7nkj6igr0gi7r7jg950lsx7dj6aipgxi6vbjsf5f5yc9h7fhii"))))
    (properties `((upstream-name . "Rsolnp")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-truncnorm" ,r-truncnorm)))
    (home-page "https://cran.r-project.org/web/packages/Rsolnp/")
    (synopsis "General non-linear optimization")
    (description "The Rsolnp package implements a general non-linear augmented
Lagrange multiplier method solver, a @dfn{sequential quadratic
programming} (SQP) based solver).")
    ;; Any version of the GPL.
    (license license:gpl2+)))

(define-public r-hardyweinberg
  (package
    (name "r-hardyweinberg")
    (version "1.6.3")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "HardyWeinberg" version))
       (sha256
        (base32
         "1irz44q6nf95h37av868f47aakwv3jgwgw217xfsfw0afkm7s25f"))))
    (properties `((upstream-name . "HardyWeinberg")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-mice" ,r-mice)
       ("r-rcpp" ,r-rcpp)
       ("r-rsolnp" ,r-rsolnp)))
    (home-page "https://cran.r-project.org/package=HardyWeinberg")
    (synopsis "Statistical tests and graphics for Hardy-Weinberg equilibrium")
    (description
     "This package contains tools for exploring Hardy-Weinberg equilibrium for
diallelic genetic marker data.  All classical tests (chi-square, exact,
likelihood-ratio and permutation tests) for Hardy-Weinberg equilibrium are
included in the package, as well as functions for power computation and for
the simulation of marker data under equilibrium and disequilibrium.  Routines
for dealing with markers on the X-chromosome are included.  Functions for
testing equilibrium in the presence of missing data by using multiple
imputation are also provided.  Implements several graphics for exploring the
equilibrium status of a large set of diallelic markers: ternary plots with
acceptance regions, log-ratio plots and Q-Q plots.")
    (license license:gpl2+)))

(define-public r-sm
  (package
    (name "r-sm")
    (version "2.2-5.6")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "sm" version))
       (sha256
        (base32
         "0c4whcx879gb4lwvqnzxl5n9xgpcqh2c54ip9ami3mwfprzcv45q"))))
    (build-system r-build-system)
    (native-inputs `(("gfortran" ,gfortran)))
    (home-page "http://www.stats.gla.ac.uk/~adrian/sm/")
    (synopsis "Smoothing methods for nonparametric regression and density estimation")
    (description
     "This is software accompanying the book 'Applied Smoothing Techniques for
Data Analysis---The Kernel Approach with S-Plus Illustrations', Oxford
University Press.  It provides smoothing methods for nonparametric regression
and density estimation")
    (license license:gpl2+)))

(define-public r-venndiagram
  (package
    (name "r-venndiagram")
    (version "1.6.20")
    (source (origin
              (method url-fetch)
              (uri (cran-uri "VennDiagram" version))
              (sha256
               (base32
                "1ic1jaxzw98si2p4n1fl4n3myhd7fpw0njb634cwhviwybzv6775"))))
    (properties `((upstream-name . "VennDiagram")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-futile-logger" ,r-futile-logger)))
    (home-page "https://cran.r-project.org/web/packages/VennDiagram/")
    (synopsis "Generate High-Resolution Venn and Euler Plots")
    (description
     "This package provides a set of functions to generate high-resolution
Venn and Euler plots.  It includes handling for several special cases,
including two-case scaling, and extensive customization of plot shape and
structure.")
    (license license:gpl2+)))

(define-public r-vioplot
  (package
    (name "r-vioplot")
    (version "0.3.4")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "vioplot" version))
       (sha256
        (base32
         "1fsklymilspzz5fzlj7666x09aglaw0v4x0yfjjzy4vr5qpjc529"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-sm" ,r-sm)
       ("r-zoo" ,r-zoo)))
    (home-page "http://wsopuppenkiste.wiso.uni-goettingen.de/~dadler")
    (synopsis "Violin plot")
    (description
     "This package provides a violin plot, which is a combination of a box
plot and a kernel density plot.")
    (license license:bsd-3)))

(define-public r-rsofia
  (package
    (name "r-rsofia")
    (version "1.1")
    (source (origin
              (method url-fetch)
              ;; This package has been removed from CRAN, so we can
              ;; only fetch it from the archives.
              (uri (string-append "https://cran.r-project.org/src/"
                                  "contrib/Archive/RSofia/RSofia_"
                                  version ".tar.gz"))
              (sha256
               (base32
                "0q931y9rcf6slb0s2lsxhgqrzy4yqwh8hb1124nxg0bjbxvjbihn"))))
    (properties `((upstream-name . "RSofia")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-rcpp" ,r-rcpp)))
    (home-page "https://cran.r-project.org/src/contrib/Archive/RSofia")
    (synopsis "Port of sofia-ml to R")
    (description "This package is a port of sofia-ml to R.  Sofia-ml is a
suite of fast incremental algorithms for machine learning that can be used for
training models for classification or ranking.")
    (license license:asl2.0)))

(define-public r-xts
  (package
    (name "r-xts")
    (version "0.12-0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "xts" version))
       (sha256
        (base32
         "0q4cc8ynp7ndmgll1jj3lxyl6wmgg89ad3wq09kjc2ngszdfc4fz"))))
    (build-system r-build-system)
    (propagated-inputs `(("r-zoo" ,r-zoo)))
    (home-page "https://github.com/joshuaulrich/xts")
    (synopsis "Extensible time series")
    (description
     "This package provides for uniform handling of R's different time-based
data classes by extending @code{zoo}, maximizing native format information
preservation and allowing for user-level customization and extension, while
simplifying cross-class interoperability.")
    (license license:gpl2+)))

(define-public r-performanceanalytics
  (package
    (name "r-performanceanalytics")
    (version "2.0.4")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "PerformanceAnalytics" version))
       (sha256
        (base32
         "0ci26hsj4wnw9g0mh4vrn0cg986cpcpx169rvw6v6rbnjxq718bq"))))
    (properties
     `((upstream-name . "PerformanceAnalytics")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-quadprog" ,r-quadprog)
       ("r-xts" ,r-xts)
       ("r-zoo" ,r-zoo)))
    (home-page "https://r-forge.r-project.org/projects/returnanalytics/")
    (synopsis "Econometric tools for performance and risk analysis")
    (description "This is a collection of econometric functions for
performance and risk analysis.  This package aims to aid practitioners and
researchers in utilizing the latest research in analysis of non-normal return
streams.  In general, it is most tested on return (rather than price) data on
a regular scale, but most functions will work with irregular return data as
well, and increasing numbers of functions will work with P&L or price data
where possible.")
    ;; Either version may be picked.
    (license (list license:gpl2 license:gpl3))))

(define-public r-laeken
  (package
    (name "r-laeken")
    (version "0.5.1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "laeken" version))
       (sha256
        (base32
         "199rjkhjjygpr6cjzab87as46acb5npi44m4yycvk7lnd0blma8s"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-boot" ,r-boot)
       ("r-mass" ,r-mass)))
    (home-page "https://cran.r-project.org/web/packages/laeken/")
    (synopsis "Estimation of indicators on social exclusion and poverty")
    (description "This package provides tools for the estimation of indicators
on social exclusion and poverty, as well as an implementation of Pareto tail
modeling for empirical income distributions.")
    (license license:gpl2+)))

(define-public r-vcd
  (package
    (name "r-vcd")
    (version "1.4-7")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "vcd" version))
       (sha256
        (base32
         "16aj688nhlcvdxzfsqh4s375v8f8vl8997dl8h1xg29b42nv52gc"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-colorspace" ,r-colorspace)
       ("r-lmtest" ,r-lmtest)
       ("r-mass" ,r-mass)))
    (home-page "https://cran.r-project.org/web/packages/vcd/")
    (synopsis "Visualizing categorical data")
    (description "This package provides visualization techniques, data sets,
summary and inference procedures aimed particularly at categorical data.
Special emphasis is given to highly extensible grid graphics.  The package was
originally inspired by the book \"Visualizing Categorical Data\" by Michael
Friendly and is now the main support package for a new book, \"Discrete Data
Analysis with R\" by Michael Friendly and David Meyer (2015).")
    (license license:gpl2)))

(define-public r-ica
  (package
    (name "r-ica")
    (version "1.0-2")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "ica" version))
       (sha256
        (base32
         "0ya1nph1zwhad0bfz4yxs27kl45yk1dhnphdlrq34p8pqrpmj8g7"))))
    (build-system r-build-system)
    (home-page "https://cran.r-project.org/web/packages/ica/")
    (synopsis "Independent component analysis")
    (description "This package provides tools for @dfn{Independent Component
Analysis} (ICA) using various algorithms: FastICA,
Information-Maximization (Infomax), and @dfn{Joint Approximate Diagonalization
of Eigenmatrices} (JADE).")
    (license license:gpl2+)))

(define-public r-dtw
  (package
    (name "r-dtw")
    (version "1.21-3")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "dtw" version))
       (sha256
        (base32
         "02hyhx1sy5h3vzh9zixy18a7d47df4k5d0wyflcvlcbsbcl6p90s"))))
    (build-system r-build-system)
    (propagated-inputs `(("r-proxy" ,r-proxy)))
    (home-page "http://dtw.r-forge.r-project.org/")
    (synopsis "Dynamic Time Warping Algorithms")
    (description "This package provides a comprehensive implementation of
@dfn{dynamic time warping} (DTW) algorithms in R.  DTW computes the
optimal (least cumulative distance) alignment between points of two time
series.  Common DTW variants covered include local (slope) and global (window)
constraints, subsequence matches, arbitrary distance definitions,
normalizations, minimum variance matching, and so on.")
    (license license:gpl2+)))

(define-public r-sdmtools
  (package
    (name "r-sdmtools")
    (version "1.1-221.2")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "SDMTools" version))
       (sha256
        (base32
         "1xvcd97ikqsfdpk2fddy3k0z1ajqga7nv9bgac9c1wnjk1gqrpgh"))))
    (properties `((upstream-name . "SDMTools")))
    (build-system r-build-system)
    (propagated-inputs `(("r-r-utils" ,r-r-utils)))
    (home-page "https://www.rforge.net/SDMTools/")
    (synopsis "Species distribution modelling tools")
    (description "This package provides a set of tools for post processing
the outcomes of species distribution modeling exercises.  It includes novel
methods for comparing models and tracking changes in distributions through
time.  It further includes methods for visualizing outcomes, selecting
thresholds, calculating measures of accuracy and landscape fragmentation
statistics, etc.")
    (license license:gpl3+)))

(define-public r-scatterplot3d
  (package
    (name "r-scatterplot3d")
    (version "0.3-41")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "scatterplot3d" version))
       (sha256
        (base32
         "152xqz9c70qab86mpgng049gxsg5f4fpf1m8dh93fb9v1avjd0sc"))))
    (build-system r-build-system)
    (home-page "https://cran.r-project.org/web/packages/scatterplot3d/")
    (synopsis "3D scatter plot")
    (description "This package provides an implementation of scatter plots for
plotting.  a three dimensional point cloud.")
    (license license:gpl2)))

(define-public r-ggridges
  (package
    (name "r-ggridges")
    (version "0.5.2")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "ggridges" version))
       (sha256
        (base32
         "03pz257aw0mkh5k75rby9givkc1ky3n5scvhjhjiz9vry9fpffmh"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-ggplot2" ,r-ggplot2)
       ("r-plyr" ,r-plyr)
       ("r-scales" ,r-scales)
       ("r-withr" ,r-withr)))
    (home-page "https://github.com/clauswilke/ggridges")
    (synopsis "Ridgeline plots in ggplot2")
    (description
     "Ridgeline plots provide a convenient way of visualizing changes in
distributions over time or space.  This package enables the creation of such
plots in @code{ggplot2}.")
    (license license:gpl2)))

(define-public r-ggjoy
  (package
    (name "r-ggjoy")
    (version "0.4.1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "ggjoy" version))
       (sha256
        (base32
         "012md2m0jqfcccb933j423m3ck31v3p0pd41gjxpyg9082y7ixyj"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-ggplot2" ,r-ggplot2)
       ("r-ggridges" ,r-ggridges)))
    (home-page "https://github.com/clauswilke/ggjoy")
    (synopsis "Joyplots in ggplot2")
    (description "Joyplots provide a convenient way of visualizing changes in
distributions over time or space.  This package enables the creation of such
plots in @code{ggplot2}.")
    (license license:gpl2)))

(define-public r-cli
  (package
    (name "r-cli")
    (version "2.0.2")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "cli" version))
       (sha256
        (base32
         "1dhkah6jvr96k4h4agcc2rfls75bpjb0j58fzaz3dc0fp3jk8229"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-assertthat" ,r-assertthat)
       ("r-crayon" ,r-crayon)
       ("r-fansi" ,r-fansi)
       ("r-glue" ,r-glue)))
    (home-page "https://github.com/r-lib/cli#readme")
    (synopsis "Helpers for developing command line interfaces")
    (description "This package provides a suite of tools designed to build
attractive command line interfaces (CLIs).  It includes tools for drawing
rules, boxes, trees, and Unicode symbols with ASCII alternatives.")
    (license license:expat)))

(define-public r-argparser
  (package
    (name "r-argparser")
    (version "0.6")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "argparser" version))
       (sha256
        (base32
         "1pxiz9jlhlnpzqn1lz349r07i7glw708w202x6dlnxp112fg7k4x"))))
    (build-system r-build-system)
    (home-page "https://bitbucket.org/djhshih/argparser")
    (synopsis "Command-line argument parser")
    (description
     "This package provides a cross-platform command-line argument parser
written purely in R with no external dependencies.  It is useful with the
Rscript front-end and facilitates turning an R script into an executable
script.")
    (license license:gpl3+)))

(define-public r-debugme
  (package
    (name "r-debugme")
    (version "1.1.0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "debugme" version))
       (sha256
        (base32
         "1c9sg55zvf10h8198jdnpamm6f66lzw3c3jnmdp9ls6na0j0xbjd"))))
    (build-system r-build-system)
    (propagated-inputs `(("r-crayon" ,r-crayon)))
    (home-page "https://github.com/r-lib/debugme#readme")
    (synopsis "Debug R packages")
    (description
     "This package allows the user to specify debug messages as special string
constants, and control debugging of packages via environment variables.")
    (license license:expat)))

(define-public r-processx
  (package
    (name "r-processx")
    (version "3.4.2")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "processx" version))
       (sha256
        (base32
         "02awswxq6wh3rl99dncw5n6c1xmd0v81xcdp2dfyi6vm6b3gz84l"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-ps" ,r-ps)
       ("r-r6" ,r-r6)))
    (home-page "https://github.com/r-lib/processx3")
    (synopsis "Execute and control system processes")
    (description
     "This package provides portable tools to run system processes in the
background.  It can check if a background process is running; wait on a
background process to finish; get the exit status of finished processes; kill
background processes and their children; restart processes.  It can read the
standard output and error of the processes, using non-blocking connections.
@code{processx} can poll a process for standard output or error, with a
timeout.  It can also poll several processes at once.")
    (license license:expat)))

(define-public r-tsp
  (package
    (name "r-tsp")
    (version "1.1-9")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "TSP" version))
       (sha256
        (base32
         "183m6crb0dv17llj86059n3hbgsahbhfcqlx0ijdzkssg11i1cy7"))))
    (properties `((upstream-name . "TSP")))
    (build-system r-build-system)
    (propagated-inputs `(("r-foreach" ,r-foreach)))
    (home-page "https://cran.r-project.org/web/packages/TSP/")
    (synopsis "Traveling salesperson problem (TSP)")
    (description "This package provides basic infrastructure and some
algorithms for the @dfn{traveling salesperson problem}(TSP) (also known as the
traveling salesman problem).")
    (license license:gpl3)))

(define-public r-qap
  (package
    (name "r-qap")
    (version "0.1-1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "qap" version))
       (sha256
        (base32
         "0d2d1ni1camixyi45lfy00f4pn3p063k7bsi8gj5scp6n15mdgb0"))))
    (build-system r-build-system)
    (native-inputs `(("gfortran" ,gfortran)))
    (home-page "https://cran.r-project.org/web/packages/qap/")
    (synopsis "Heuristics for the quadratic assignment problem (QAP)")
    (description "This package implements heuristics for the @dfn{quadratic
assignment problem} (QAP).  Currently only a simulated annealing heuristic is
available.")
    (license license:gpl3)))

(define-public r-gclus
  (package
    (name "r-gclus")
    (version "1.3.2")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "gclus" version))
       (sha256
        (base32
         "1cz0g0i972955hhaji30rx8448x7f3as7z1sww9i5h86ybgirilw"))))
    (build-system r-build-system)
    (propagated-inputs `(("r-cluster" ,r-cluster)))
    (home-page "https://cran.r-project.org/web/packages/gclus/")
    (synopsis "Clustering graphics")
    (description "This package orders panels in scatterplot matrices and
parallel coordinate displays by some merit index.  It contains various indices
of merit, ordering functions, and enhanced versions of @code{pairs} and
@code{parcoord} which color panels according to their merit level.")
    (license license:gpl2+)))

(define-public r-webshot
  (package
    (name "r-webshot")
    (version "0.5.2")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "webshot" version))
       (sha256
        (base32
         "0gq4h8cw51z95yvsnf38kj5l58wgljkm0dalmi8mn1sp06bxr0zi"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-callr" ,r-callr)
       ("r-jsonlite" ,r-jsonlite)
       ("r-magrittr" ,r-magrittr)))
    (home-page "https://github.com/wch/webshot/")
    (synopsis "Take screenshots of web pages")
    (description
     "Webshot makes it easy to take screenshots of web pages from within R.
It can also run Shiny applications locally and take screenshots of the
application; and it can render and screenshot static as well as interactive R
Markdown documents.")
    (license license:gpl2)))

(define-public r-seriation
  (package
    (name "r-seriation")
    (version "1.2-8")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "seriation" version))
       (sha256
        (base32
         "1zbdxq0s5rc5v307b69fw9k52m0654ls7pf22lh35ggirig6lwsk"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-cluster" ,r-cluster)
       ("r-colorspace" ,r-colorspace)
       ("r-dendextend" ,r-dendextend)
       ("r-gclus" ,r-gclus)
       ("r-gplots" ,r-gplots)
       ("r-mass" ,r-mass)
       ("r-qap" ,r-qap)
       ("r-registry" ,r-registry)
       ("r-tsp" ,r-tsp)))
    (native-inputs `(("gfortran" ,gfortran)))
    (home-page "https://s2.smu.edu/IDA/seriation/")
    (synopsis "Infrastructure for ordering objects using seriation")
    (description
     "This package provides infrastructure for seriation with an
implementation of several seriation/sequencing techniques to reorder matrices,
dissimilarity matrices, and dendrograms.  It also provides (optimally)
reordered heatmaps, color images and clustering visualizations like
dissimilarity plots, and visual assessment of cluster tendency plots (VAT and
iVAT).")
    (license license:gpl3)))

(define-public r-xfun
  (package
    (name "r-xfun")
    (version "0.12")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "xfun" version))
       (sha256
        (base32 "0sgh8kafi9x1glmmcp1ly827pm8q7fsfngbplr41fbb4nc9363df"))))
    (build-system r-build-system)
    (home-page "https://github.com/yihui/xfun")
    (synopsis "Miscellaneous functions")
    (description
     "This package provides miscellaneous functions commonly used in other
packages maintained by Yihui Xie.")
    (license license:expat)))

(define-public r-utf8
  (package
    (name "r-utf8")
    (version "1.1.4")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "utf8" version))
       (sha256
        (base32
         "0m0ywg8k3blfiahxvh1i4zn9dksrlc937d2lbza5fc38zjnrrnpn"))))
    (build-system r-build-system)
    (home-page "https://github.com/patperry/r-utf8")
    (synopsis "Unicode text processing")
    (description
     "This package provides tools to process and print UTF-8 encoded
international text (Unicode).  Input, validate, normalize, encode, format, and
display.")
    (license license:asl2.0)))

(define-public r-zeallot
  (package
    (name "r-zeallot")
    (version "0.1.0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "zeallot" version))
       (sha256
        (base32
         "1sd1igcfnv27pa3bqxlbyxchi562h7grnjg1l7wxx3bwr49i57s3"))))
    (build-system r-build-system)
    (home-page "https://github.com/nteetor/zeallot")
    (synopsis "Multiple, unpacking, and destructuring assignment")
    (description
     "This package provides a @code{%<-%} operator to perform multiple,
unpacking, and destructuring assignment in R.  The operator unpacks the
right-hand side of an assignment into multiple values and assigns these values
to variables on the left-hand side of the assignment.")
    (license license:expat)))

(define-public r-vctrs
  (package
    (name "r-vctrs")
    (version "0.2.4")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "vctrs" version))
       (sha256
        (base32
         "15sgzs6afvmhssk6jcg41rn3bvmzmbm4sgca6f6x8lfrsazvdj6w"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-digest" ,r-digest)
       ("r-ellipsis" ,r-ellipsis)
       ("r-glue" ,r-glue)
       ("r-rlang" ,r-rlang)))
    (native-inputs
     `(("r-knitr" ,r-knitr)))
    (home-page "https://github.com/r-lib/vctrs")
    (synopsis "Vector helpers")
    (description
     "There are three main goals to the @code{vctrs} package:

@enumerate
@item To propose @code{vec_size()} and @code{vec_type()} as alternatives to
  @code{length()} and @code{class()}.  These definitions are paired with a
  framework for type-coercion and size-recycling.
@item To define type- and size-stability as desirable function properties, use
  them to analyse existing base function, and to propose better alternatives.
  This work has been particularly motivated by thinking about the ideal
  properties of @code{c()}, @code{ifelse()}, and @code{rbind()}.
@item To provide a new @code{vctr} base class that makes it easy to create new
  S3 vectors.  @code{vctrs} provides methods for many base generics in terms of
  a few new @code{vctrs} generics, making implementation considerably simpler
  and more robust.
@end enumerate\n")
    (license license:gpl3)))

(define-public r-pillar
  (package
    (name "r-pillar")
    (version "1.4.3")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "pillar" version))
       (sha256
        (base32
         "02sn7zw80wq33jgxk2i6m5jb83sk7y72dfhgyy0apfinv05w92ss"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-cli" ,r-cli)
       ("r-crayon" ,r-crayon)
       ("r-fansi" ,r-fansi)
       ("r-rlang" ,r-rlang)
       ("r-utf8" ,r-utf8)
       ("r-vctrs" ,r-vctrs)))
    (home-page "https://github.com/r-lib/pillar")
    (synopsis "Coloured formatting for columns")
    (description
     "This package provides a @code{pillar} generic designed for formatting
columns of data using the full range of colours provided by modern
terminals.")
    (license license:gpl3)))

(define-public r-uuid
  (package
    (name "r-uuid")
    (version "0.1-4")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "uuid" version))
       (sha256
        (base32
         "0gm9ii7ncvllxbvyk6srsiinjmqyj7lmh84w43x4nhqpvafj9q4q"))))
    (build-system r-build-system)
    (home-page "https://www.rforge.net/uuid")
    (synopsis "Tools for generating and handling of UUIDs")
    (description
     "This package provides tools for generating and handling of
@dfn{Universally Unique Identifiers} (UUIDs).")
    (license license:expat)))

(define-public r-tinytex
  (package
    (name "r-tinytex")
    (version "0.21")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "tinytex" version))
       (sha256
        (base32
         "088zzc2v0izbcs45p19v547pi78vkr08ibpvvi1g9bkbya4x3mq9"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-xfun" ,r-xfun)))
    (home-page "https://github.com/yihui/tinytex")
    (synopsis "Helper functions for TeX Live and compiling LaTeX documents")
    (description
     "This package provides helper functions to install and maintain the LaTeX
distribution named TinyTeX, a lightweight, cross-platform, portable, and
easy-to-maintain version of TeX Live.  This package also contains helper
functions to compile LaTeX documents, and install missing LaTeX packages
automatically.")
    (license license:expat)))

(define-public r-network
  (package
    (name "r-network")
    (version "1.16.0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "network" version))
       (sha256
        (base32
         "0dnf1wl3za2lhx2lwd8smhlijl1cfhckgr8zz9piiirrfi2m2kx2"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-magrittr" ,r-magrittr)
       ("r-tibble" ,r-tibble)))
    (home-page "https://statnet.org/")
    (synopsis "Classes for relational data")
    (description
     "This package provides tools to create and modify network objects.  The
@code{network} class can represent a range of relational data types, and
supports arbitrary vertex/edge/graph attributes.")
    (license license:gpl2+)))

(define-public r-statnet-common
  (package
    (name "r-statnet-common")
    (version "4.3.0")
    (source
      (origin
        (method url-fetch)
        (uri (cran-uri "statnet.common" version))
        (sha256
          (base32
            "0ng90i0wm9wlyhjbnmnylc1bbqw396p1dr7f402dyry9x9ck6jl3"))))
    (properties
      `((upstream-name . "statnet.common")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-coda" ,r-coda)))
    (home-page "https://statnet.org")
    (synopsis "R scripts and utilities used by the Statnet software")
    (description "This package provides non-statistical utilities used by the
software developed by the Statnet Project.")
    (license license:gpl3)))

(define-public r-statcheck
  (package
    (name "r-statcheck")
    (version "1.3.0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "statcheck" version))
       (sha256
        (base32
         "0ivybdcrymlsfv6pg6p5bv70qdvgxf2vgp0kf4r0pf2fcvav1mcp"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-ggplot2" ,r-ggplot2)
       ("r-plyr" ,r-plyr)
       ("r-rmarkdown" ,r-rmarkdown)))
    (home-page "https://cran.r-project.org/web/packages/statcheck/")
    (synopsis "Extract statistics from articles and recompute p-values")
    (description "This package can automatically extract statistical
null-hypothesis significant testing (NHST) results from articles and recompute
the p-values based on the reported test statistic and degrees of freedom to
detect possible inconsistencies.")
    (license license:gpl2)))

(define-public r-sna
  (package
    (name "r-sna")
    (version "2.5")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "sna" version))
       (sha256
        (base32
         "1j3i6300m686qqfmyvadim377cd3mplzgj6mandygw8brg50id8k"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-network" ,r-network)
       ("r-statnet-common" ,r-statnet-common)))
    (home-page "https://statnet.org")
    (synopsis "Tools for social network analysis")
    (description
     "This package provides a range of tools for social network analysis,
including node and graph-level indices, structural distance and covariance
methods, structural equivalence detection, network regression, random graph
generation, and 2D/3D network visualization.")
    (license license:gpl2+)))

(define-public r-tfisher
  (package
    (name "r-tfisher")
    (version "0.2.0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "TFisher" version))
       (sha256
        (base32
         "0vz74ww1lf1prfwz74hfsi3a8nzq8ss7aqjr85c1d87vss2796xx"))))
    (properties `((upstream-name . "TFisher")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-matrix" ,r-matrix)
       ("r-mvtnorm" ,r-mvtnorm)
       ("r-sn" ,r-sn)))
    (home-page "https://cran.r-project.org/web/packages/TFisher/")
    (synopsis "Optimal thresholding Fisher's p-value combination method")
    (description
     "This package provides the @dfn{cumulative distribution function} (CDF),
quantile, and statistical power calculator for a collection of thresholding
Fisher's p-value combination methods, including Fisher's p-value combination
method, truncated product method and, in particular, soft-thresholding
Fisher's p-value combination method which is proven to be optimal in some
context of signal detection.  The p-value calculator for the omnibus version
of these tests are also included.")
    (license license:gpl2)))

(define-public r-ttr
  (package
    (name "r-ttr")
    (version "0.23-6")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "TTR" version))
       (sha256
        (base32
         "0rg22ma3x07s9djlxscfw5jcq1gbir05cwhgvwfi53x1sf4hmhdg"))))
    (properties `((upstream-name . "TTR")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-curl" ,r-curl)
       ("r-xts" ,r-xts)
       ("r-zoo" ,r-zoo)))
    (home-page "https://github.com/joshuaulrich/TTR")
    (synopsis "Technical trading rules")
    (description
     "This package provides functions and data to construct technical trading
rules with R.")
    (license license:gpl2)))

(define-public r-leaps
  (package
    (name "r-leaps")
    (version "3.1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "leaps" version))
       (sha256
        (base32
         "1dn3yl1p03n0iynd1vsdkrr0fhmvgrmfkv37y7n371765h83lz1x"))))
    (build-system r-build-system)
    (native-inputs `(("gfortran" ,gfortran)))
    (home-page "https://cran.r-project.org/web/packages/leaps/")
    (synopsis "Regression subset selection")
    (description
     "This package provides tools for regression subset selection, including
exhaustive search.")
    (license license:gpl2+)))

(define-public r-splus2r
  (package
    (name "r-splus2r")
    (version "1.2-2")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "splus2R" version))
       (sha256
        (base32
         "0xrbj8vxy0pc6hl7m8abv71d3hjw47cl51s7j7priadyqczkq6sz"))))
    (properties `((upstream-name . "splus2R")))
    (build-system r-build-system)
    (native-inputs `(("gfortran" ,gfortran)))
    (home-page "https://cran.r-project.org/web/packages/splus2R/")
    (synopsis "Supplemental S-PLUS functionality in R")
    (description
     "Currently there are many functions in S-PLUS that are missing in R.  To
facilitate the conversion of S-PLUS packages to R packages, this package
provides some missing S-PLUS functionality in R.")
    (license license:gpl2)))

(define-public r-ifultools
  (package
    (name "r-ifultools")
    (version "2.0-5")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "ifultools" version))
       (sha256
        (base32
         "040kvbczcmmbaiaz0k0pdq9af541pjj6iwzh1a3w4szh9w6b5a3j"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-mass" ,r-mass)
       ("r-splus2r" ,r-splus2r)))
    (home-page "https://cran.r-project.org/web/packages/ifultools/")
    (synopsis "Insightful research tools")
    (description "This package provides C code used by the wmtsa, fractal, and
sapa R packages.")
    (license license:gpl2)))

(define-public r-sapa
  (package
    (name "r-sapa")
    (version "2.0-2")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "sapa" version))
       (sha256
        (base32
         "056xlh14dnzq4x7sbp7ff2k61jxy7110a742b502vz549qfrr5ds"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-ifultools" ,r-ifultools)
       ("r-splus2r" ,r-splus2r)))
    (home-page "https://cran.r-project.org/web/packages/sapa/")
    (synopsis "Spectral analysis for physical applications")
    (description "This package provides software for the book Spectral
Analysis for Physical Applications, Donald B. Percival and Andrew T. Walden,
Cambridge University Press, 1993.")
    (license license:gpl2)))

(define-public r-aggregation
  (package
    (name "r-aggregation")
    (version "1.0.1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "aggregation" version))
       (sha256
        (base32
         "0j9g604m2ccc7hcy02539yja9cf3xcbl25gvp838bp4x8w18my46"))))
    (build-system r-build-system)
    (home-page "https://cran.r-project.org/web/packages/aggregation/")
    (synopsis "Methods for p-value aggregation")
    (description
     "This package contains functionality for performing the following methods
of p-value aggregation: Fisher's method, the Lancaster method (weighted
Fisher's method), and Sidak correction.")
    (license license:gpl3)))

(define-public r-quantmod
  (package
    (name "r-quantmod")
    (version "0.4.17")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "quantmod" version))
       (sha256
        (base32
         "1ss441rwlr88kz212m0wgx0hwgwi41rhy1jncg2lgqzqfvr5dzqa"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-curl" ,r-curl)
       ("r-ttr" ,r-ttr)
       ("r-xts" ,r-xts)
       ("r-zoo" ,r-zoo)))
    (home-page "https://cran.r-project.org/web/packages/quantmod/")
    (synopsis "Quantitative financial modelling framework")
    (description "This package provides a quantitative financial modelling
framework to allow users to specify, build, trade, and analyse quantitative
financial trading strategies.")
    (license license:gpl3)))

(define-public r-tseries
  (package
    (name "r-tseries")
    (version "0.10-47")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "tseries" version))
       (sha256
        (base32
         "0yzvc9djp3angvxdxqi60wi726y76ablsb71q88ycvw0avgpf8r0"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-quadprog" ,r-quadprog)
       ("r-quantmod" ,r-quantmod)
       ("r-zoo" ,r-zoo)))
    (native-inputs
     `(("gfortran" ,gfortran)))
    (home-page "https://cran.r-project.org/web/packages/tseries/")
    (synopsis "Time series analysis and computational finance")
    (description
     "This package provides functions relating to time series analysis and
computational finance.")
    (license license:gpl2)))

(define-public r-wmtsa
  (package
    (name "r-wmtsa")
    (version "2.0-3")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "wmtsa" version))
       (sha256
        (base32
         "1q436krz5p1f4a7a7sya6a9rh9x9mi8zzcgq66gbk9w9w4hcqcj6"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-ifultools" ,r-ifultools)
       ("r-mass" ,r-mass)
       ("r-splus2r" ,r-splus2r)))
    (home-page "https://cran.r-project.org/web/packages/wmtsa/")
    (synopsis "Wavelet methods for time series analysis")
    (description
     "This package provides software to accompany the book \"Wavelet Methods
for Time Series Analysis\", Donald B. Percival and Andrew T. Walden, Cambridge
University Press, 2000.")
    (license license:gpl2)))

(define-public r-tsa
  (package
    (name "r-tsa")
    (version "1.2")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "TSA" version))
       (sha256
        (base32
         "0gjfqibwdznz0nka95k4fjm935svxjpnqfywwz403crn2lh30h6q"))))
    (properties `((upstream-name . "TSA")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-leaps" ,r-leaps)
       ("r-locfit" ,r-locfit)
       ("r-mgcv" ,r-mgcv)))
    (home-page "https://homepage.divms.uiowa.edu/~kchan/TSA.htm")
    (synopsis "Time series analysis")
    (description
     "This package contains R functions and datasets detailed in the book
\"Time Series Analysis with Applications in R (second edition)\" by Jonathan
Cryer and Kung-Sik Chan.")
    (license license:gpl2+)))

(define-public r-extradistr
  (package
    (name "r-extradistr")
    (version "1.8.11")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "extraDistr" version))
       (sha256
        (base32
         "1vvqv1d4hxa025gmm8cbiph63qsqy87l3ri5idd524gyz3chbcl3"))))
    (properties `((upstream-name . "extraDistr")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-rcpp" ,r-rcpp)))
    (home-page "https://github.com/twolodzko/extraDistr")
    (synopsis "Additional univariate and multivariate distributions")
    (description
     "This package implements density, distribution functions, quantile
functions and random generation functions for a large number of univariate and
multivariate distributions.")
    (license license:gpl2)))

(define-public r-fractal
  (package
    (name "r-fractal")
    (version "2.0-4")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "fractal" version))
       (sha256
        (base32
         "18lr9z0gslvfc3z8vyj3krqj3bfhg60zv1fzinrwwkc4cpk1w7mp"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-ifultools" ,r-ifultools)
       ("r-mass" ,r-mass)
       ("r-sapa" ,r-sapa)
       ("r-scatterplot3d" ,r-scatterplot3d)
       ("r-splus2r" ,r-splus2r)
       ("r-wmtsa" ,r-wmtsa)))
    (home-page "https://cran.r-project.org/web/packages/fractal/")
    (synopsis "Fractal time series modeling and analysis")
    (description
     "This package provides tools for stochastic fractal and deterministic
chaotic time series analysis.")
    (license license:gpl2)))

(define-public r-urca
  (package
    (name "r-urca")
    (version "1.3-0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "urca" version))
       (sha256
        (base32
         "1akaqwf3fvvvx4sgfn641fd4sj51s0701pvfl6s5hnz2k0iwh732"))))
    (build-system r-build-system)
    (propagated-inputs `(("r-nlme" ,r-nlme)))
    (native-inputs `(("gfortran" ,gfortran)))
    (home-page "https://cran.r-project.org/web/packages/urca/")
    (synopsis "Unit root and cointegration tests for time series data")
    (description
     "This package provides unit root and cointegration tests encountered in
applied econometric analysis.")
    (license license:gpl2+)))

(define-public r-cubature
  (package
    (name "r-cubature")
    (version "2.0.4")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "cubature" version))
       (sha256
        (base32
         "0jpyq8j7x06dpiz29w48av879ygldzgls9z810192hsymkmfaz6r"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-rcpp" ,r-rcpp)))
    (home-page "https://github.com/bnaras/cubature")
    (synopsis "Adaptive multivariate integration over hypercubes")
    (description
     "This package is an R wrapper around the cubature C library for adaptive
multivariate integration over hypercubes.  This version provides both
@code{hcubature} and @code{pcubature} routines in addition to a vector
interface.")
    ;; The included cubature C library is released under GPLv2+, but the
    ;; wrapper declares the license to be GPLv3+.
    (license (list license:gpl2+ license:gpl3+))))

(define-public r-trend
  (package
    (name "r-trend")
    (version "1.1.2")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "trend" version))
       (sha256
        (base32
         "09b6ycyfgs4xlhx6kn6qm5rl2acp58hzhv8qclzn3kb1wjjyvxy5"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-extradistr" ,r-extradistr)))
    (native-inputs
     `(("gfortran" ,gfortran)))
    (home-page "https://cran.r-project.org/web/packages/trend/")
    (synopsis "Non-parametric trend tests and change-point detection")
    (description
     "The analysis of environmental data often requires the detection of
trends and change-points.  This package includes tests for trend
detection (Cox-Stuart Trend Test, Mann-Kendall Trend Test, (correlated)
Hirsch-Slack Test, partial Mann-Kendall Trend Test, multivariate (multisite)
Mann-Kendall Trend Test, (Seasonal) Sen's slope, partial Pearson and Spearman
correlation trend test), change-point detection (Lanzante's test procedures,
Pettitt's test, Buishand Range Test, Buishand U Test, Standard Normal
Homogeinity Test), detection of non-randomness (Wallis-Moore Phase Frequency
Test, Bartels rank von Neumann's ratio test, Wald-Wolfowitz Test) and the two
sample Robust Rank-Order Distributional Test.")
    (license license:gpl3)))

(define-public r-expm
  (package
    (name "r-expm")
    (version "0.999-4")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "expm" version))
       (sha256
        (base32
         "15k0acg2aqb2ajhwal6l7vhhp03m4lg579805d34554cl0kn9l2q"))))
    (build-system r-build-system)
    (propagated-inputs `(("r-matrix" ,r-matrix)))
    (native-inputs `(("gfortran" ,gfortran)))
    (home-page "https://r-forge.r-project.org/projects/expm/")
    (synopsis "Tools for matrix exponentials and related quantities")
    (description
     "This package provides tools for the computation of the matrix
exponential, logarithm, square root, and related quantities.")
    (license license:gpl2+)))

(define-public r-complexplus
  (package
    (name "r-complexplus")
    (version "2.1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "complexplus" version))
       (sha256
        (base32
         "16w9v7d1ckavqmr86l34frr37pkvdn0iqnb17ssb8xaggns5lgqx"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-expm" ,r-expm)
       ("r-matrix" ,r-matrix)))
    (home-page "https://cran.r-project.org/web/packages/complexplus/")
    (synopsis "Functions of complex or real variables")
    (description
     "This package extends several functions to the complex domain, including
the matrix exponential and logarithm, and the determinant.")
    (license license:gpl2)))

(define-public r-phontools
  (package
    (name "r-phontools")
    (version "0.2-2.1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "phonTools" version))
       (sha256
        (base32
         "01i481mhswsys3gpasw9gn6nxkfmi7bz46g5c84m13pg0cv8hxc7"))))
    (properties `((upstream-name . "phonTools")))
    (build-system r-build-system)
    (home-page "http://www.santiagobarreda.com/rscripts.html")
    (synopsis "Tools for phonetic and acoustic analyses")
    (description
     "This package contains tools for the organization, display, and analysis
of the sorts of data frequently encountered in phonetics research and
experimentation, including the easy creation of IPA vowel plots, and the
creation and manipulation of WAVE audio files.")
    (license license:bsd-2)))

(define-public r-np
  (package
    (name "r-np")
    (version "0.60-10")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "np" version))
       (sha256
        (base32
         "06h8k0kdv5s258jr6s08fabvlycrbs7iq34jk2f2hfmqm2y4nyx2"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-boot" ,r-boot)
       ("r-cubature" ,r-cubature)
       ("r-quadprog" ,r-quadprog)
       ("r-quantreg" ,r-quantreg)))
    (home-page "https://github.com/JeffreyRacine/R-Package-np")
    (synopsis "Non-parametric kernel smoothing methods for mixed data types")
    (description "This package provides non-parametric (and semi-parametric)
kernel methods that seamlessly handle a mix of continuous, unordered, and
ordered factor data types.")
    ;; Any version of the GPL.
    (license license:gpl3+)))

(define-public r-powerplus
  (package
    (name "r-powerplus")
    (version "3.1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "powerplus" version))
       (sha256
        (base32
         "0ayp6x34hkzgris4j3zbbs0r23n81bhww3wgfyy630ri4sk6brrn"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-complexplus" ,r-complexplus)
       ("r-expm" ,r-expm)
       ("r-mass" ,r-mass)
       ("r-matrix" ,r-matrix)
       ("r-phontools" ,r-phontools)))
    (home-page "https://cran.r-project.org/web/packages/powerplus/")
    (synopsis "Exponentiation operations")
    (description
     "This package provides tools for the computation of matrix and scalar
exponentiation.")
    (license license:gpl2)))

(define-public r-egg
  (package
    (name "r-egg")
    (version "0.4.5")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "egg" version))
       (sha256
        (base32
         "1fy7srpiavfn8kyrr1m84an7acgwi6ydzrg71m3b0vk7y9ybmj0m"))))
    (properties `((upstream-name . "egg")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-ggplot2" ,r-ggplot2)
       ("r-gridextra" ,r-gridextra)
       ("r-gtable" ,r-gtable)))
    (home-page "https://cran.r-project.org/web/packages/egg")
    (synopsis "Extensions for ggplot2")
    (description
     "This package provides miscellaneous functions to help customize ggplot2
objects.  High-level functions are provided to post-process ggplot2 layouts
and allow alignment between plot panels, as well as setting panel sizes to
fixed values.  Other functions include a custom @code{geom}, and helper
functions to enforce symmetric scales or add tags to facetted plots.")
    (license license:gpl3)))

(define-public r-heatmaply
  (package
    (name "r-heatmaply")
    (version "1.1.0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "heatmaply" version))
       (sha256
        (base32
         "133q8ir45vhfxs2lnd96k97g21ihg2arfhp349kmk339pk32fcxz"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-assertthat" ,r-assertthat)
       ("r-colorspace" ,r-colorspace)
       ("r-dendextend" ,r-dendextend)
       ("r-egg" ,r-egg)
       ("r-ggplot2" ,r-ggplot2)
       ("r-htmlwidgets" ,r-htmlwidgets)
       ("r-magrittr" ,r-magrittr)
       ("r-plotly" ,r-plotly)
       ("r-rcolorbrewer" ,r-rcolorbrewer)
       ("r-reshape2" ,r-reshape2)
       ("r-scales" ,r-scales)
       ("r-seriation" ,r-seriation)
       ("r-viridis" ,r-viridis)
       ("r-webshot" ,r-webshot)))
    (native-inputs
     `(("r-knitr" ,r-knitr)))
    (home-page "https://cran.r-project.org/package=heatmaply")
    (synopsis "Interactive cluster heat maps using plotly")
    (description
     "This package enables you to create interactive cluster heatmaps that can
be saved as a stand-alone HTML file, embedded in R Markdown documents or in a
Shiny app, and made available in the RStudio viewer pane.  Hover the mouse
pointer over a cell to show details or drag a rectangle to zoom.  A heatmap is
a popular graphical method for visualizing high-dimensional data, in which a
table of numbers is encoded as a grid of colored cells.  The rows and columns
of the matrix are ordered to highlight patterns and are often accompanied by
dendrograms.")
    ;; Either version of the license.
    (license (list license:gpl2 license:gpl3))))

(define-public r-h5
  (package
    (name "r-h5")
    (version "0.9.9")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "h5" version))
       (sha256
        (base32
         "14p7i1sj24ky87kd7qr3n9fc9l64s0bp0rwbyl6i2x69xn75gpsx"))))
    (build-system r-build-system)
    (inputs
     `(("zlib" ,zlib)
       ("hdf5" ,hdf5)))
    (native-inputs
     `(("which" ,which)))
    (propagated-inputs
     `(("r-rcpp" ,r-rcpp)))
    (home-page "https://github.com/mannau/h5")
    (synopsis "Interface to the HDF5 Library")
    (description
     "This package provides an S4 interface to the HDF5 library supporting
fast storage and retrieval of R-objects like vectors, matrices and arrays to
binary files in a language independent format.  The HDF5 format can therefore
be used as an alternative to R's save/load mechanism.  Since h5 is able to
access only subsets of stored data it can also handle data sets which do not
fit into memory.")
    (license license:bsd-2)))

(define-public r-cgdsr
  (package
    (name "r-cgdsr")
    (version "1.3.0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "cgdsr" version))
       (sha256
        (base32
         "07yc819hkabpzzh0g0cbqza6bcfy67b2marrzz1lj97f9iba78ja"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-httr" ,r-httr)
       ("r-r-methodss3" ,r-r-methodss3)
       ("r-r-oo" ,r-r-oo)))
    (home-page "https://github.com/cBioPortal/cgdsr")
    (synopsis "R-based API for accessing the MSKCC Cancer Genomics Data Server")
    (description
     "This package provides a basic set of R functions for querying the Cancer
Genomics Data Server (CGDS), hosted by the Computational Biology Center at
Memorial-Sloan-Kettering Cancer Center (MSKCC).")
    (license license:lgpl3)))

(define-public r-import
  (package
    (name "r-import")
    (version "1.1.0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "import" version))
       (sha256
        (base32
         "0blf9539rbfwcmw8zsb4k58slb4pdnc075v34vmyjw752fznhcji"))))
    (build-system r-build-system)
    (home-page "https://github.com/smbache/import")
    (synopsis "Import mechanism for R")
    (description
     "This is an alternative mechanism for importing objects from packages.
The syntax allows for importing multiple objects from a package with a single
command in an expressive way.  The import package bridges some of the gap
between using @code{library} (or @code{require}) and direct (single-object)
imports.  Furthermore the imported objects are not placed in the current
environment.  It is also possible to import objects from stand-alone @code{.R}
files.")
    (license license:expat)))

(define-public r-shinyace
  (package
    (name "r-shinyace")
    (version "0.4.1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "shinyAce" version))
       (sha256
        (base32
         "1m33dfm2kjirvgix7ybv1kbzgjkicdpv411g9c0q3fw6rnyhfxxn"))))
    (properties `((upstream-name . "shinyAce")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-shiny" ,r-shiny)
       ("r-jsonlite" ,r-jsonlite)))
    (home-page "https://cran.r-project.org/web/packages/shinyAce/")
    (synopsis "Ace editor bindings for Shiny")
    (description
     "This package provides Ace editor bindings to enable a rich text editing
environment within Shiny.")
    (license license:expat)))

(define-public r-randomizr
  (package
    (name "r-randomizr")
    (version "0.20.0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "randomizr" version))
       (sha256
        (base32
         "0dljyfldnardaps3fq6vi5wcs9x6qfaq5apapa78c51lnaa6fn9h"))))
    (properties `((upstream-name . "randomizr")))
    (build-system r-build-system)
    (native-inputs
     `(("r-knitr" ,r-knitr)))
    (home-page "https://declaredesign.org/r/randomizr/")
    (synopsis "Tools for common forms of random assignment and sampling")
    (description
     "This package provides tools for generating random assignments for common
experimental designs and random samples for common sampling designs.")
    (license license:expat)))

(define-public r-base64url
  (package
    (name "r-base64url")
    (version "1.4")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "base64url" version))
       (sha256
        (base32
         "0n1c2b68vza1dh7sk38v6biiwm72c4jpl79kpdg1bsb0hq9qy18x"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-backports" ,r-backports)))
    (home-page "https://github.com/mllg/base64url")
    (synopsis "Fast and URL-safe base64 encoder and decoder")
    (description
     "This package provides a URL-safe base64 encoder and decoder.  In
contrast to RFC3548, the 62nd character (@code{+}) is replaced with @code{-},
the 63rd character (@code{/}) is replaced with @code{_}.  Furthermore, the
encoder does not fill the string with trailing @code{=}.  The resulting
encoded strings comply to the regular expression pattern @code{[A-Za-z0-9_-]}
and thus are safe to use in URLs or for file names.  The package also comes
with a simple base32 encoder/decoder suited for case insensitive file
systems.")
    (license license:gpl3)))

(define-public r-radiant-data
  (package
    (name "r-radiant-data")
    (version "1.3.4")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "radiant.data" version))
       (sha256
        (base32
         "19sjjb49inrfl7jzq4zpwhdslni0zrp30bl58pisin29ka3ylpzs"))
       (modules '((guix build utils)))
       (snippet
        '(begin
           ;; Delete files that are under CC-NC-SA.
           (delete-file-recursively "inst/app/tools/help")
           #t))))
    (properties `((upstream-name . "radiant.data")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-base64enc" ,r-base64enc)
       ("r-broom" ,r-broom)
       ("r-car" ,r-car)
       ("r-curl" ,r-curl)
       ("r-dplyr" ,r-dplyr)
       ("r-dt" ,r-dt)
       ("r-glue" ,r-glue)
       ("r-ggplot2" ,r-ggplot2)
       ("r-import" ,r-import)
       ("r-jsonlite" ,r-jsonlite)
       ("r-knitr" ,r-knitr)
       ("r-lubridate" ,r-lubridate)
       ("r-magrittr" ,r-magrittr)
       ("r-markdown" ,r-markdown)
       ("r-mass" ,r-mass)
       ("r-patchwork" ,r-patchwork)
       ("r-plotly" ,r-plotly)
       ("r-psych" ,r-psych)
       ("r-randomizr" ,r-randomizr)
       ("r-readr" ,r-readr)
       ("r-readxl" ,r-readxl)
       ("r-rlang" ,r-rlang)
       ("r-rmarkdown" ,r-rmarkdown)
       ("r-rstudioapi" ,r-rstudioapi)
       ("r-scales" ,r-scales)
       ("r-shiny" ,r-shiny)
       ("r-shinyfiles" ,r-shinyfiles)
       ("r-shinyace" ,r-shinyace)
       ("r-stringi" ,r-stringi)
       ("r-tibble" ,r-tibble)
       ("r-tidyr" ,r-tidyr)
       ("r-writexl" ,r-writexl)))
    (home-page "https://github.com/radiant-rstats/radiant.data")
    (synopsis "Data menu for Radiant: business analytics using R and Shiny")
    (description
     "The Radiant Data menu includes interfaces for loading, saving, viewing,
visualizing, summarizing, transforming, and combining data.  It also contains
functionality to generate reproducible reports of the analyses conducted in
the application.")
    (license license:agpl3)))

(define-public r-algdesign
  (package
    (name "r-algdesign")
    (version "1.2.0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "AlgDesign" version))
       (sha256
        (base32 "0ammlg148gk0p24fh700116nd66636np0jb1wwh0axq5jphwk1pz"))))
    (properties `((upstream-name . "AlgDesign")))
    (build-system r-build-system)
    (home-page "https://github.com/jvbraun/AlgDesign")
    (synopsis "Algorithmic experimental design")
    (description
     "This package provides tools to calculate exact and approximate theory
experimental designs for D, A, and I criteria.  Very large designs may be
created.  Experimental designs may be blocked or blocked designs created from
a candidate list, using several criteria.  The blocking can be done when whole
and within plot factors interact.")
    (license license:gpl2+)))

(define-public r-signal
  (package
    (name "r-signal")
    (version "0.7-6")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "signal" version))
       (sha256
        (base32
         "1vsxramz5qd9q9s3vlqzmfdpmwl2rhlb2n904zw6f0fg0xxjfq3b"))))
    (build-system r-build-system)
    (propagated-inputs `(("r-mass" ,r-mass)))
    (native-inputs `(("gfortran" ,gfortran)))
    (home-page "https://cran.r-project.org/web/packages/signal/")
    (synopsis "Signal processing")
    (description
     "This package provides a set of signal processing functions originally
written for Matlab and GNU Octave.  It includes filter generation utilities,
filtering functions, resampling routines, and visualization of filter models.
It also includes interpolation functions.")
    (license license:gpl2)))

(define-public r-gsubfn
  (package
    (name "r-gsubfn")
    (version "0.7")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "gsubfn" version))
       (sha256
        (base32
         "00j6b8b6xsx6v370h220x233rpk6asca78165y3d48jpwvwisdc9"))))
    (build-system r-build-system)
    (propagated-inputs `(("r-proto" ,r-proto)))
    (home-page "https://code.google.com/archive/p/gsubfn/")
    (synopsis "Utilities for strings and function arguments.")
    (description
     "This package provides @code{gsubfn} which is like @code{gsub} but can
take a replacement function or certain other objects instead of the
replacement string.  Matches and back references are input to the replacement
function and replaced by the function output.  @code{gsubfn} can be used to
split strings based on content rather than delimiters and for quasi-perl-style
string interpolation.  The package also has facilities for translating
formulas to functions and allowing such formulas in function calls instead of
functions.")
    (license license:gpl2+)))

(define-public r-sqldf
  (package
    (name "r-sqldf")
    (version "0.4-11")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "sqldf" version))
       (sha256
        (base32
         "0q12vsb53p2wchgp8wfz5bk08wfnm0jxjrakclj4jyy6x3a7ksff"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-chron" ,r-chron)
       ("r-dbi" ,r-dbi)
       ("r-gsubfn" ,r-gsubfn)
       ("r-proto" ,r-proto)
       ("r-rsqlite" ,r-rsqlite)))
    (home-page "https://github.com/ggrothendieck/sqldf")
    (synopsis "Manipulate R data frames using SQL")
    (description
     "The @code{sqldf} function is typically passed a single argument which is
an SQL select statement where the table names are ordinary R data frame names.
@code{sqldf} transparently sets up a database, imports the data frames into
that database, performs the SQL statement and returns the result using a
heuristic to determine which class to assign to each column of the returned
data frame.  The @code{sqldf} or @code{read.csv.sql} functions can also be
used to read filtered files into R even if the original files are larger than
R itself can handle.")
    (license license:gpl2)))

(define-public r-abind
  (package
    (name "r-abind")
    (version "1.4-5")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "abind" version))
       (sha256
        (base32
         "0b1zd8jbnl6l292cr9rb50m09fy3ylxvzkpgi5lfb1nbzddcwfis"))))
    (build-system r-build-system)
    (home-page "https://cran.r-project.org/web/packages/abind/")
    (synopsis "Combine multidimensional arrays")
    (description
     "This package provides tools to combine multidimensional arrays into a
single array.  This is a generalization of @code{cbind} and @code{rbind}.  It
works with vectors, matrices, and higher-dimensional arrays.  It also provides
the functions @code{adrop}, @code{asub}, and @code{afill} for manipulating,
extracting and replacing data in arrays.")
    (license license:lgpl2.0+)))

(define-public r-prroc
  (package
    (name "r-prroc")
    (version "1.3.1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "PRROC" version))
       (sha256
        (base32
         "1m28h8pcd78049lz2qixhkcr9h5b3jik3maqzfbvq9y58z71i4a7"))))
    (properties `((upstream-name . "PRROC")))
    (build-system r-build-system)
    (home-page "https://cran.r-project.org/web/packages/PRROC/")
    (synopsis "Precision-Recall and ROC curves for weighted and unweighted data")
    (description
     "This package computes the areas under the @dfn{precision-recall} (PR)
and ROC curve for weighted (e.g. soft-labeled) and unweighted data.  In
contrast to other implementations, the interpolation between points of the PR
curve is done by a non-linear piecewise function.  In addition to the areas
under the curves, the curves themselves can also be computed and plotted by a
specific S3-method.")
    (license license:gpl3)))

(define-public r-vim
  (package
    (name "r-vim")
    (version "5.1.1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "VIM" version))
       (sha256
        (base32
         "0w22ir0gvym7gqd6nw2j7w5ivlb3az1dkfxv33imimkb7c83056a"))))
    (properties `((upstream-name . "VIM")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-car" ,r-car)
       ("r-colorspace" ,r-colorspace)
       ("r-data-table" ,r-data-table)
       ("r-e1071" ,r-e1071)
       ("r-laeken" ,r-laeken)
       ("r-magrittr" ,r-magrittr)
       ("r-mass" ,r-mass)
       ("r-nnet" ,r-nnet)
       ("r-ranger" ,r-ranger)
       ("r-rcpp" ,r-rcpp)
       ("r-robustbase" ,r-robustbase)
       ("r-sp" ,r-sp)
       ("r-vcd" ,r-vcd)))
    (home-page "https://github.com/alexkowa/VIM")
    (synopsis "Visualization and imputation of missing values")
    (description
     "This package provides tools for the visualization of missing and/or
imputed values are introduced, which can be used for exploring the data and
the structure of the missing and/or imputed values.  Depending on this
structure of the missing values, the corresponding methods may help to
identify the mechanism generating the missing values and allows to explore the
data including missing values.  In addition, the quality of imputation can be
visually explored using various univariate, bivariate, multiple and
multivariate plot methods.")
    (license license:gpl2+)))

(define-public r-fnn
  (package
    (name "r-fnn")
    (version "1.1.3")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "FNN" version))
       (sha256
        (base32
         "0cllqlnynm5yaj4r64mqyyfc8phkb38rwssq8k8ikgfgr4jklxny"))))
    (properties `((upstream-name . "FNN")))
    (build-system r-build-system)
    (home-page "https://cran.r-project.org/web/packages/FNN")
    (synopsis "Fast nearest neighbor search algorithms and applications")
    (description
     "This package provides cover-tree and kd-tree fast k-nearest neighbor
search algorithms.  Related applications including KNN classification,
regression and information measures are implemented.")
    ;; The DESCRIPTION file erroneously states that GPL version 2.1 or
    ;; later can be used.
    (license license:gpl2+)))

(define-public r-smoother
  (package
    (name "r-smoother")
    (version "1.1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "smoother" version))
       (sha256
        (base32
         "0nqr1bvlr5bnasqg74zmknjjl4x28kla9h5cxpga3kq5z215pdci"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-ttr" ,r-ttr)))
    (home-page "https://cran.r-project.org/web/packages/smoother")
    (synopsis "Functions relating to the smoothing of numerical data")
    (description
     "This package provides a collection of methods for smoothing numerical
data, commencing with a port of the Matlab gaussian window smoothing function.
In addition, several functions typically used in smoothing of financial data
are included.")
    (license license:gpl2)))

(define-public r-riverplot
  (package
    (name "r-riverplot")
    (version "0.6")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "riverplot" version))
       (sha256
        (base32
         "0q1icpny8nkxyjhawyjzwrw8qlz0ayn2xyrsqrm4vkxyv6c9xk8z"))))
    (build-system r-build-system)
    (home-page "https://logfc.wordpress.com")
    (synopsis "Sankey or ribbon plots")
    (description
     "Sankey plots are a type of diagram that is convenient to illustrate how
flow of information, resources etc. separates and joins, much like observing
how rivers split and merge.  For example, they can be used to compare
different clusterings.  This package provides an implementation of Sankey
plots for R.")
    (license license:gpl2+)))

(define-public r-dyn
  (package
    (name "r-dyn")
    (version "0.2-9.6")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "dyn" version))
       (sha256
        (base32
         "16fqv9k7yxdgybwzafjkyqm16qpgqz13lcjpi6a1nc8xbzlzh0gb"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-zoo" ,r-zoo)))
    (home-page "https://cran.r-project.org/web/packages/dyn")
    (synopsis "Time series regression")
    (description
     "This package provides the dyn class interfaces @code{ts}, @code{irts},
@code{zoo} and @code{zooreg} time series classes to @code{lm}, @code{glm},
@code{loess}, @code{quantreg::rq}, @code{MASS::rlm},
@code{MCMCpack::MCMCregress()}, @code{quantreg::rq()},
@code{randomForest::randomForest()} and other regression functions, allowing
those functions to be used with time series including specifications that may
contain lags, diffs and missing values.")
    ;; Any GPL version.
    (license license:gpl2+)))

(define-public r-catdap
  (package
    (name "r-catdap")
    (version "1.3.5")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "catdap" version))
       (sha256
        (base32
         "0fyhl69z2lznymvpzxra9qvcg85ggzkfjy68c6mzdmf1ja44d2k5"))))
    (build-system r-build-system)
    (native-inputs
     `(("gfortran" ,gfortran)))
    (home-page "https://cran.r-project.org/web/packages/catdap/")
    (synopsis "Tools for categorical data analysis")
    (description
     "This package provides functions for analyzing multivariate data.
Dependencies of the distribution of the specified variable (response
variable) to other variables (explanatory variables) are derived and
evaluated by the @dfn{Akaike Information Criterion} (AIC).")
    (license license:gpl2+)))

(define-public r-arules
  (package
    (name "r-arules")
    (version "1.6-4")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "arules" version))
       (sha256
        (base32
         "003c5cd3xzq39h7c19px077ygm0n1v7k83icy5zzrnkagyds2p8n"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-matrix" ,r-matrix)))
    (home-page "https://github.com/mhahsler/arules")
    (synopsis "Mining association rules and frequent itemsets")
    (description
     "This package provides an infrastructure for representing, manipulating
and analyzing transaction data and patterns (frequent itemsets and association rules).
It also provides C implementations of the association mining algorithms Apriori
and Eclat.")
    (license license:gpl3)))

(define-public r-parsedate
  (package
    (name "r-parsedate")
    (version "1.2.0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "parsedate" version))
       (sha256
        (base32
         "0gb3w6hmwxayhijpf36p5dk4h6bbdps57x3cgikwvvxkgi83rarr"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-rematch2" ,r-rematch2)))
    (home-page "https://github.com/gaborcsardi/parsedate")
    (synopsis
     "Recognize and parse dates in various formats")
    (description
     "This package provides three functions for dealing with dates:
@code{parse_iso_8601} recognizes and parses all valid ISO 8601 date and
time formats, @code{parse_date} parses dates in unspecified formats,
and @code{format_iso_8601} formats a date in ISO 8601 format.")
    (license license:gpl2)))

(define-public r-abc-data
  (package
    (name "r-abc-data")
    (version "1.0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "abc.data" version))
       (sha256
        (base32
         "1bv1n68ah714ws58cf285n2s2v5vn7382lfjca4jxph57lyg8hmj"))))
    (properties `((upstream-name . "abc.data")))
    (build-system r-build-system)
    (home-page "https://cran.r-project.org/web/packages/abc.data/")
    (synopsis "Data for Approximate Bayesian Computation (ABC) package")
    (description
     "This package contains data which are used by functions of the abc
package which implements several @dfn{Approximate Bayesian Computation} (ABC)
algorithms for performing parameter estimation, model selection, and
goodness-of-fit.")
    (license license:gpl3+)))

(define-public r-abc
  (package
    (name "r-abc")
    (version "2.1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "abc" version))
       (sha256
        (base32
         "0ngzaaz2y2s03fhngvwipmy4kq38xrmyddaz6a6l858rxvadrlhb"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-abc-data" ,r-abc-data)
       ("r-locfit" ,r-locfit)
       ("r-mass" ,r-mass)
       ("r-nnet" ,r-nnet)
       ("r-quantreg" ,r-quantreg)))
    (home-page "https://cran.r-project.org/web/packages/abc/")
    (synopsis "Tools for Approximate Bayesian Computation (ABC)")
    (description
     "This package implements several @dfn{Approximate Bayesian
Computation} (ABC) algorithms for performing parameter estimation, model
selection, and goodness-of-fit.  Cross-validation tools are also available for
measuring the accuracy of ABC estimates, and to calculate the
misclassification probabilities of different models.")
    (license license:gpl3+)))

(define-public r-zip
  (package
    (name "r-zip")
    (version "2.0.4")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "zip" version))
       (sha256
        (base32
         "1c02amk3pl6xir5jnbfiwiv2wvpkpbkkb1w71y6lf2yk7g3d0pdb"))))
    (build-system r-build-system)
    (home-page "https://github.com/gaborcsardi/zip")
    (synopsis "Cross-platform Zip compression")
    (description
     "This package provides a cross-platform Zip compression library for R.
It is a replacement for the @code{zip} function, that does not require any
additional external tools on any platform.")
    (license license:cc0)))

(define-public r-openxlsx
  (package
    (name "r-openxlsx")
    (version "4.1.4")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "openxlsx" version))
       (sha256
        (base32
         "1mwxldw9i9nfksx1i6h1kfs7vmsz9fgyllbsipar4vnfyqhqp8q7"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-rcpp" ,r-rcpp)
       ("r-stringi" ,r-stringi)
       ("r-zip" ,r-zip)))
    (home-page "https://github.com/awalker89/openxlsx")
    (synopsis "Read, write and edit XLSX files")
    (description
     "This package simplifies the creation of Excel @code{.xlsx} files by
providing a high level interface to writing, styling and editing worksheets.
Through the use of Rcpp, read/write times are comparable to the @code{xlsx}
and @code{XLConnect} packages with the added benefit of removing the
dependency on Java.")
    (license license:gpl3)))

(define-public r-rio
  (package
    (name "r-rio")
    (version "0.5.16")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "rio" version))
       (sha256
        (base32
         "0rfl56fdawlhc98451a9lcb6a6m56kw0i7dvd5hx58z025d8vsyk"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-curl" ,r-curl)
       ("r-data-table" ,r-data-table)
       ("r-foreign" ,r-foreign)
       ("r-haven" ,r-haven)
       ("r-openxlsx" ,r-openxlsx)
       ("r-readxl" ,r-readxl)
       ("r-tibble" ,r-tibble)))
    (home-page "https://github.com/leeper/rio")
    (synopsis "Swiss-army knife for data I/O")
    (description
     "This package provides streamlined data import and export infrastructure
by making assumptions that the user is probably willing to make: @code{import}
and @code{export} determine the data structure from the file extension,
reasonable defaults are used for data import and export (e.g.,
@code{stringsAsFactors=FALSE}), web-based import is natively
supported (including from SSL/HTTPS), compressed files can be read directly
without explicit decompression, and fast import packages are used where
appropriate.  An additional convenience function, @code{convert}, provides a
simple method for converting between file types.")
    (license license:gpl2)))

(define-public r-maptools
  (package
    (name "r-maptools")
    (version "0.9-9")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "maptools" version))
       (sha256
        (base32
         "0v4llkxk8qs61vq4ykvaim4k23aagdaz0p62ns7zfq02sln3pfk9"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-foreign" ,r-foreign)
       ("r-lattice" ,r-lattice)
       ("r-sp" ,r-sp)))
    (home-page "https://r-forge.r-project.org/projects/maptools/")
    (synopsis "Tools for reading and handling spatial objects")
    (description
     "This package provides a set of tools for manipulating and reading
geographic data, in particular ESRI Shapefiles.  It includes binary access to
GSHHG shoreline files.  The package also provides interface wrappers for
exchanging spatial objects with other R packages.")
    ;; The C source files from shapelib are released under the Expat license.
    ;; The R code is released under GPL version 2 or later.
    (license (list license:gpl2+
                   license:expat))))

(define-public r-later
  (package
    (name "r-later")
    (version "1.0.0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "later" version))
       (sha256
        (base32
         "11xjavj7siz0xv2ffq1ld4bwl35jyrcfpvvs4p3ilpifxx49hyr7"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-bh" ,r-bh)
       ("r-rcpp" ,r-rcpp)
       ("r-rlang" ,r-rlang)))
    (home-page "https://github.com/r-lib/later")
    (synopsis "Utilities for delaying function execution")
    (description
     "This package provides tools to execute arbitrary R or C functions some
time after the current time, after the R execution stack has emptied.")
    (license license:gpl2+)))

(define-public r-promises
  (package
    (name "r-promises")
    (version "1.1.0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "promises" version))
       (sha256
        (base32
         "01l0ydjvvy6afcg5d6pzvk1ikd3djq8n2flv8c831ksn68z0zsn8"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-later" ,r-later)
       ("r-magrittr" ,r-magrittr)
       ("r-r6" ,r-r6)
       ("r-rcpp" ,r-rcpp)
       ("r-rlang" ,r-rlang)))
    (home-page "https://rstudio.github.io/promises")
    (synopsis "Abstractions for promise-based asynchronous programming")
    (description
     "This package provides fundamental abstractions for doing asynchronous
programming in R using promises.  Asynchronous programming is useful for
allowing a single R process to orchestrate multiple tasks in the background
while also attending to something else.  Semantics are similar to JavaScript
promises, but with a syntax that is idiomatic R.")
    (license license:expat)))

(define-public r-dosnow
  (package
    (name "r-dosnow")
    (version "1.0.18")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "doSNOW" version))
       (sha256
        (base32
         "0rj72z5505cprh6wykhhiz08l9bmd966srqh2qypwivf321bvrvh"))))
    (properties `((upstream-name . "doSNOW")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-foreach" ,r-foreach)
       ("r-iterators" ,r-iterators)
       ("r-snow" ,r-snow)))
    (home-page "https://cran.r-project.org/web/packages/doSNOW")
    (synopsis "Foreach parallel adaptor for the snow package")
    (description
     "This package provides a parallel backend for the @code{%dopar%} function
using the @code{snow} package.")
    (license license:gpl2)))

(define-public r-snowfall
  (package
   (name "r-snowfall")
   (version "1.84-6.1")
   (source (origin
            (method url-fetch)
            (uri (cran-uri "snowfall" version))
            (sha256
             (base32 "13941rlw1jsdjsndp1plzj1cq5aqravizkrqn6l25r9im7rnsi2w"))))
   (build-system r-build-system)
   (propagated-inputs
    `(("r-snow" ,r-snow)))
   (home-page "https://cran.r-project.org/web/packages/snowfall/")
   (synopsis "Easier cluster computing")
   (description "This package is a usability wrapper around snow for easier
development of parallel R programs.  This package offers e.g. extended error
checks, and additional functions.  All functions work in sequential mode, too,
if no cluster is present or wished.  The package is also designed as connector
to the cluster management tool @code{sfCluster}, but can also used without
it.")
   (license license:gpl2+)))

(define-public r-rappdirs
  (package
    (name "r-rappdirs")
    (version "0.3.1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "rappdirs" version))
       (sha256
        (base32
         "0ji6sg3bdn5gazkq14xmmcq7jnbsyxw4lzmmbgv6526j2vn93n1g"))))
    (build-system r-build-system)
    (home-page "https://cran.r-project.org/web/packages/rappdirs/")
    (synopsis "Determine where to save data, caches, and logs")
    (description
     "This package provides an easy way to determine which directories on the
user's computer should be used to save data, caches and logs.  It is a port of
Python's @url{https://github.com/ActiveState/appdirs,Appdirs} to R.")
    (license license:expat)))

(define-public r-renv
  (package
    (name "r-renv")
    (version "0.9.3")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "renv" version))
       (sha256
        (base32
         "02ayfgbpw4b58148dcxz31anaxncwczmxs1zzkskwj0rzhb2x60r"))))
    (properties `((upstream-name . "renv")))
    (build-system r-build-system)
    (home-page "https://rstudio.github.io/renv")
    (synopsis "Project environments")
    (description
     "This package provides a dependency management toolkit for R.  Using
renv, you can create and manage project-local R libraries, save the state of
these libraries to a lockfile, and later restore your library as required.
Together, these tools can help make your projects more isolated, portable, and
reproducible.")
    (license license:expat)))

(define-public r-learnr
  (package
    (name "r-learnr")
    (version "0.10.1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "learnr" version))
       (sha256
        (base32
         "08xwmms6x58y3dsfbl9c6d03145hb4ij97nqr1cc9dxxilmr6x31"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-checkmate" ,r-checkmate)
       ("r-ellipsis" ,r-ellipsis)
       ("r-evaluate" ,r-evaluate)
       ("r-htmltools" ,r-htmltools)
       ("r-htmlwidgets" ,r-htmlwidgets)
       ("r-jsonlite" ,r-jsonlite)
       ("r-knitr" ,r-knitr)
       ("r-markdown" ,r-markdown)
       ("r-rappdirs" ,r-rappdirs)
       ("r-renv" ,r-renv)
       ("r-rmarkdown" ,r-rmarkdown)
       ("r-rprojroot" ,r-rprojroot)
       ("r-shiny" ,r-shiny)
       ("r-withr" ,r-withr)))
    (home-page "https://rstudio.github.io/learnr/")
    (synopsis "Interactive tutorials for R")
    (description
     "This package provides tools to create interactive tutorials using R
Markdown.  Use a combination of narrative, figures, videos, exercises, and
quizzes to create self-paced tutorials for learning about R and R packages.")
    (license license:asl2.0)))

(define-public r-analytics
  (package
    (name "r-analytics")
    (version "3.0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "analytics" version))
       (sha256
        (base32
         "0js3c8lwj3knccb55nq03cbjlf4w390p9aid2mi5x80l3ayd9in1"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-car" ,r-car)
       ("r-cluster" ,r-cluster)
       ("r-fractal" ,r-fractal)
       ("r-lmtest" ,r-lmtest)
       ("r-mass" ,r-mass)
       ("r-np" ,r-np)
       ("r-powerplus" ,r-powerplus)
       ("r-robust" ,r-robust)
       ("r-trend" ,r-trend)
       ("r-tsa" ,r-tsa)
       ("r-urca" ,r-urca)
       ("r-vim" ,r-vim)))
    (home-page "https://cran.r-project.org/web/packages/analytics/")
    (synopsis "Collection of data analysis tools")
    (description
     "This package is a collection of data analysis tools.  It includes tools
for regression outlier detection in a fitted linear model, stationary
bootstrap using a truncated geometric distribution, a comprehensive test for
weak stationarity, column means by group, weighted biplots, and a heuristic to
obtain a better initial configuration in non-metric MDS.")
    (license license:gpl2)))

(define-public r-reticulate
  (package
    (name "r-reticulate")
    (version "1.15")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "reticulate" version))
       (sha256
        (base32
         "03dmnx9jhxx6vfbv2i5n6sln38kb9zkshz982pg3l9i4jjf3xns7"))))
    (build-system r-build-system)
    (inputs `(("python" ,python)))
    (propagated-inputs
     `(("r-rappdirs" ,r-rappdirs)
       ("r-jsonlite" ,r-jsonlite)
       ("r-matrix" ,r-matrix)
       ("r-rcpp" ,r-rcpp)))
    (native-inputs
     `(("r-knitr" ,r-knitr)))
    (home-page "https://github.com/rstudio/reticulate")
    (synopsis "R interface to Python")
    (description
     "This package provides an interface from R to Python modules, classes,
and functions.  When calling into Python, R data types are automatically
converted to their equivalent Python types.  When values are returned from
Python to R they are converted back to R types.")
    (license license:asl2.0)))

(define-public r-bibtex
  (package
    (name "r-bibtex")
    (version "0.4.2.2")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "bibtex" version))
       (sha256
        (base32
         "140hkjzdp3033cvji861rd06z1ixgpnn4n5amygqsmhnixk8ff07"))))
    (build-system r-build-system)
    (propagated-inputs `(("r-stringr" ,r-stringr)))
    (home-page "https://github.com/romainfrancois/bibtex")
    (synopsis "Bibtex parser")
    (description "This package provides a utility for R to parse a bibtex
file.")
    (license license:gpl2+)))

(define-public r-ggseqlogo
  (package
    (name "r-ggseqlogo")
    (version "0.1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "ggseqlogo" version))
       (sha256
        (base32
         "13q6kcpxrqxqbji889fx63p0nsi08lk5yymkchig75r5k1d18ky1"))))
    (build-system r-build-system)
    (propagated-inputs `(("r-ggplot2" ,r-ggplot2)))
    (home-page "https://github.com/omarwagih/ggseqlogo")
    (synopsis "ggplot2 extension for drawing genetic sequence logos")
    (description
     "The range of functions provided by this package makes it possible to
draw highly versatile genomic sequence logos.  Features include, but are not
limited to, modifying colour schemes and fonts used to draw the logo,
generating multiple logo plots, and aiding the visualisation with annotations.
Sequence logos can easily be combined with other ggplot2 plots.")
    ;; Unspecified version of the LGPL.
    (license license:lgpl3+)))

(define-public r-ggsci
  (package
    (name "r-ggsci")
    (version "2.9")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "ggsci" version))
       (sha256
        (base32
         "0g73x6grbka7ahjh6z23m3wrcifp5rdfdiasbl8lq4sp6rplxwaa"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-ggplot2" ,r-ggplot2)
       ("r-scales" ,r-scales)))
    (home-page "https://nanx.me/ggsci/")
    (synopsis "Scientific journal and sci-fi themed color palettes for ggplot2")
    (description
     "This package provides a collection of ggplot2 color palettes inspired by
plots in scientific journals, data visualization libraries, science fiction
movies, and TV shows.")
    (license license:gpl3)))

(define-public r-ggsignif
  (package
    (name "r-ggsignif")
    (version "0.6.0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "ggsignif" version))
       (sha256
        (base32
         "17j9hg967k1wp9xw3x84mqss58jkb8pvlrnlchz4i1hklgykxqbg"))))
    (build-system r-build-system)
    (native-inputs
     `(("r-knitr" ,r-knitr)))
    (propagated-inputs
     `(("r-ggplot2" ,r-ggplot2)))
    (home-page "https://github.com/const-ae/ggsignif")
    (synopsis "Significance brackets for ggplot2")
    (description
     "Enrich your ggplots with group-wise comparisons.  This package provides
an easy way to indicate if two groups are significantly different.  Commonly
this is shown by a bracket on top connecting the groups of interest which
itself is annotated with the level of significance.  The package provides a
single layer that takes the groups for comparison and the test as arguments
and adds the annotation to the plot.")
    (license license:gpl3)))

(define-public r-ggpubr
  (package
    (name "r-ggpubr")
    (version "0.2.5")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "ggpubr" version))
       (sha256
        (base32
         "0kb3hpmnhj4mkbx1kx0kv5y22himr8dijqx7ra0h8hi0pf2l2ha7"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-cowplot" ,r-cowplot)
       ("r-dplyr" ,r-dplyr)
       ("r-ggplot2" ,r-ggplot2)
       ("r-ggrepel" ,r-ggrepel)
       ("r-ggsci" ,r-ggsci)
       ("r-ggsignif" ,r-ggsignif)
       ("r-glue" ,r-glue)
       ("r-gridextra" ,r-gridextra)
       ("r-magrittr" ,r-magrittr)
       ("r-polynom" ,r-polynom)
       ("r-purrr" ,r-purrr)
       ("r-rlang" ,r-rlang)
       ("r-scales" ,r-scales)
       ("r-tidyr" ,r-tidyr)))
    (home-page "http://www.sthda.com/english/rpkgs/ggpubr")
    (synopsis "ggplot2-based publication-ready plots")
    (description
     "The ggplot2 package is an excellent and flexible package for elegant
data visualization in R.  However the default generated plots require some
formatting before we can send them for publication.  The ggpubr package
provides some easy-to-use functions for creating and customizing ggplot2-based
publication-ready plots.")
    (license license:gpl2)))

(define-public r-ellipse
  (package
    (name "r-ellipse")
    (version "0.4.1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "ellipse" version))
       (sha256
        (base32
         "0g82vc51m3c1k0hnpp2zla6amxxgk2mmkl8ssnsc49jv3599r6hs"))))
    (build-system r-build-system)
    (home-page "https://cran.r-project.org/web/packages/ellipse/")
    (synopsis "Functions for drawing ellipses and ellipse-like confidence regions")
    (description
     "This package contains various routines for drawing ellipses and
ellipse-like confidence regions, implementing the plots described in Murdoch
and Chow (1996), A graphical display of large correlation matrices, The
American Statistician 50, 178-180.  There are also routines implementing the
profile plots described in Bates and Watts (1988), Nonlinear Regression
Analysis and its Applications.")
    (license license:gpl2+)))

(define-public r-flashclust
  (package
    (name "r-flashclust")
    (version "1.01-2")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "flashClust" version))
       (sha256
        (base32
         "0l4lpz451ll7f7lfxmb7ds24ppzhfg1c3ypvydglcc35p2dq99s8"))))
    (properties `((upstream-name . "flashClust")))
    (build-system r-build-system)
    (native-inputs `(("gfortran" ,gfortran)))
    (home-page "https://cran.r-project.org/web/packages/flashClust/")
    (synopsis "Implementation of optimal hierarchical clustering")
    (description
     "This package provides a fast implementation of hierarchical
clustering.")
    (license license:gpl2+)))

(define-public r-factominer
  (package
    (name "r-factominer")
    (version "2.3")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "FactoMineR" version))
       (sha256
        (base32
         "0ldgf3daksh6lpblhqys67m4mxqx3q9s9n5plfam6dwshfik0ky6"))))
    (properties `((upstream-name . "FactoMineR")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-car" ,r-car)
       ("r-cluster" ,r-cluster)
       ("r-ellipse" ,r-ellipse)
       ("r-flashclust" ,r-flashclust)
       ("r-ggplot2" ,r-ggplot2)
       ("r-ggrepel" ,r-ggrepel)
       ("r-lattice" ,r-lattice)
       ("r-leaps" ,r-leaps)
       ("r-mass" ,r-mass)
       ("r-scatterplot3d" ,r-scatterplot3d)))
    (home-page "http://factominer.free.fr")
    (synopsis "Multivariate exploratory data analysis and data mining")
    (description
     "This package provides exploratory data analysis methods to summarize,
visualize and describe datasets.  The main principal component methods are
available, those with the largest potential in terms of applications:
principal component analysis (PCA) when variables are quantitative,
correspondence analysis (CA) and multiple correspondence analysis (MCA) when
variables are categorical, Multiple Factor Analysis when variables are
structured in groups, etc. and hierarchical cluster analysis.")
    (license license:gpl2+)))

(define-public r-factoextra
  (package
    (name "r-factoextra")
    (version "1.0.7")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "factoextra" version))
       (sha256
        (base32
         "1allvdjhd3pq8xz30b1cymwcik5iaahghrjrlnn54cwkfhfg0kv2"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-abind" ,r-abind)
       ("r-cluster" ,r-cluster)
       ("r-dendextend" ,r-dendextend)
       ("r-factominer" ,r-factominer)
       ("r-ggplot2" ,r-ggplot2)
       ("r-ggpubr" ,r-ggpubr)
       ("r-ggrepel" ,r-ggrepel)
       ("r-reshape2" ,r-reshape2)
       ("r-tidyr" ,r-tidyr)))
    (home-page "http://www.sthda.com/english/rpkgs/factoextra")
    (synopsis "Extract and visualize the results of multivariate data analyses")
    (description
     "This package provides some easy-to-use functions to extract and
visualize the output of multivariate data analyses, including
@code{PCA} (Principal Component Analysis), @code{CA} (Correspondence
Analysis), @code{MCA} (Multiple Correspondence Analysis), @code{FAMD} (Factor
Analysis of Mixed Data), @code{MFA} (Multiple Factor Analysis) and
@code{HMFA} (Hierarchical Multiple Factor Analysis) functions from different R
packages.  It contains also functions for simplifying some clustering analysis
steps and provides ggplot2-based elegant data visualization.")
    (license license:gpl2)))

(define-public r-fansi
  (package
    (name "r-fansi")
    (version "0.4.1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "fansi" version))
       (sha256
        (base32
         "028ywjy538psnmdnddvy5jr3idzffr4hikzr4x97x0m30g4fws9w"))))
    (build-system r-build-system)
    (native-inputs
     `(("r-knitr" ,r-knitr))) ; for vignettes
    (home-page "https://github.com/brodieG/fansi")
    (synopsis "ANSI control sequence aware string functions")
    (description
     "This package provides counterparts to R string manipulation functions
that account for the effects of ANSI text formatting control sequences.")
    (license license:gpl2+)))

(define-public r-nbclust
  (package
    (name "r-nbclust")
    (version "3.0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "NbClust" version))
       (sha256
        (base32
         "1vwb48zy6ln1ddpqmfngii1i80n8qmqyxnzdp6gbaq96lakl3w3c"))))
    (properties `((upstream-name . "NbClust")))
    (build-system r-build-system)
    (home-page "https://sites.google.com/site/malikacharrad/research/nbclust-package")
    (synopsis "Determine the best number of clusters in a data set")
    (description
     "NbClust provides 30 indexes for determining the optimal number of
clusters in a data set and offers the best clustering scheme from different
results to the user.")
    (license license:gpl2)))

(define-public r-hdf5r
  (package
    (name "r-hdf5r")
    (version "1.3.2")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "hdf5r" version))
       (sha256
        (base32
         "0c2p06k9bp9rf0fyavnxw5d8jr2bbgx3gjblahz581cpvsfksj9i"))))
    (build-system r-build-system)
    (inputs
     `(("hdf5" ,hdf5)
       ("zlib" ,zlib)))
    (propagated-inputs
     `(("r-bit64" ,r-bit64)
       ("r-r6" ,r-r6)))
    (native-inputs
     `(("r-knitr" ,r-knitr)))
    (home-page "https://hhoeflin.github.io/hdf5r")
    (synopsis "Interface to the HDF5 binary data format")
    (description
     "HDF5 is a data model, library and file format for storing and managing
large amounts of data.  This package provides a nearly feature complete,
object oriented wrapper for the HDF5 API using R6 classes.  Additionally,
functionality is added so that HDF5 objects behave very similar to their
corresponding R counterparts.")
    (license license:asl2.0)))

(define-public r-itertools
  (package
    (name "r-itertools")
    (version "0.1-3")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "itertools" version))
       (sha256
        (base32
         "1ls5biiva10pb1dj3ph4griykb9vam02hkrdmlr5a5wf660hg6xn"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-iterators" ,r-iterators)))
    (home-page "https://cran.r-project.org/web/packages/itertools/")
    (synopsis "Iterator tools")
    (description
     "This package provides various tools for creating iterators, many
patterned after functions in the Python @code{itertools} module, and others
patterned after functions in the snow package.")
    (license license:gpl2)))

(define-public r-polynom
  (package
    (name "r-polynom")
    (version "1.4-0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "polynom" version))
       (sha256
        (base32
         "1pflscwc0qzdf0y60j7s0dkglgmz18xajywfbn6s263idyr8idy5"))))
    (build-system r-build-system)
    (home-page "https://cran.r-project.org/web/packages/polynom/")
    (synopsis "Functions for univariate polynomial manipulations")
    (description
     "This package provides a collection of functions to implement a class for
univariate polynomial manipulations.")
    (license license:gpl2)))

(define-public r-gbrd
  (package
    (name "r-gbrd")
    (version "0.4-11")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "gbRd" version))
       (sha256
        (base32
         "06x97rw5i6v6cgjxkfhxnw4dn7lghn5q6ra7ri5ag1x9dkfzcl82"))))
    (properties `((upstream-name . "gbRd")))
    (build-system r-build-system)
    (home-page "https://cran.r-project.org/web/packages/gbRd/")
    (synopsis "Utilities for processing Rd objects and files")
    (description
     "This package provides utilities for processing Rd objects and files.
Extract argument descriptions and other parts of the help pages of
functions.")
    (license license:gpl2+)))

(define-public r-rjags
  (package
    (name "r-rjags")
    (version "4-10")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "rjags" version))
       (sha256
        (base32
         "1nhaim84ww8fd6m8xlpmngqcnp2qpql29ahc38366fxja3ghngmx"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-coda" ,r-coda)))
    (inputs
     `(("jags" ,jags)))
    (native-inputs
     `(("pkg-config" ,pkg-config)))
    (home-page "http://mcmc-jags.sourceforge.net")
    (synopsis "Bayesian graphical models using MCMC")
    (description
     "This package provides an R interface to the JAGS MCMC library.  JAGS is
Just Another Gibbs Sampler.  It is a program for analysis of Bayesian
hierarchical models using Markov Chain Monte Carlo (MCMC) simulation.")
    (license license:gpl2)))

(define-public r-rdpack
  (package
    (name "r-rdpack")
    (version "0.11-1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "Rdpack" version))
       (sha256
        (base32
         "080y15p2hl4jsq91ak2f1y2kx1iqq5c5wzyx3zyhjwp01cahy0jq"))))
    (properties `((upstream-name . "Rdpack")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-bibtex" ,r-bibtex)
       ("r-gbrd" ,r-gbrd)))
    (home-page "https://github.com/GeoBosh/Rdpack")
    (synopsis "Update and manipulate Rd documentation objects")
    (description
     "This package provides functions for manipulation of R documentation
objects, including functions @code{reprompt()} and @code{ereprompt()} for
updating Rd documentation for functions, methods and classes; it also includes
Rd macros for citations and import of references from bibtex files for use in
Rd files and roxygen2 comments, as well as many functions for manipulation of
references and Rd files.")
    (license license:gpl2+)))

(define-public r-officer
  (package
    (name "r-officer")
    (version "0.3.8")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "officer" version))
       (sha256
        (base32
         "0xhx5n6qksyh2s9hvwhnc8y0hn362asc5y94ld06snad786hz0rw"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-magrittr" ,r-magrittr)
       ("r-r6" ,r-r6)
       ("r-uuid" ,r-uuid)
       ("r-xml2" ,r-xml2)
       ("r-zip" ,r-zip)))
    (native-inputs
     `(("r-knitr" ,r-knitr)))
    (home-page "https://davidgohel.github.io/officer")
    (synopsis "Manipulation of Word and PowerPoint documents")
    (description
     "This package provides tools to access and manipulate Word and PowerPoint
documents from R.  The package focuses on tabular and graphical reporting from
R; it also provides two functions that let users get document content into
data objects.  A set of functions lets add and remove images, tables and
paragraphs of text in new or existing documents.  When working with PowerPoint
presentations, slides can be added or removed; shapes inside slides can also
be added or removed.  When working with Word documents, a cursor can be used
to help insert or delete content at a specific location in the document.")
    (license license:gpl3)))

(define-public r-abn
  (package
    (name "r-abn")
    (version "2.2")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "abn" version))
       (sha256
        (base32
         "19w6bdjyp4zwqs6p0flry4qxqynf9rh8ykdrfrp61wrdf7kysw0d"))))
    (build-system r-build-system)
    (inputs
     `(("gsl" ,gsl)))
    (propagated-inputs
     `(("r-lme4" ,r-lme4)
       ("r-mass" ,r-mass)
       ("r-nnet" ,r-nnet)
       ("r-rcpp" ,r-rcpp)
       ("r-rcpparmadillo" ,r-rcpparmadillo)
       ("r-rjags" ,r-rjags)))
    (home-page "https://r-bayesian-networks.org/")
    (synopsis "Modelling multivariate data with additive bayesian networks")
    (description
     "Bayesian network analysis is a form of probabilistic graphical models
which derives from empirical data a directed acyclic graph, DAG, describing
the dependency structure between random variables.  An additive Bayesian
network model consists of a form of a DAG where each node comprises a
@dfn{generalized linear model} (GLM).  Additive Bayesian network models are
equivalent to Bayesian multivariate regression using graphical modelling, they
generalises the usual multivariable regression, GLM, to multiple dependent
variables.  This package provides routines to help determine optimal Bayesian
network models for a given data set, where these models are used to identify
statistical dependencies in messy, complex data.")
    (license license:gpl2+)))

(define-public r-acd
  (package
    (name "r-acd")
    (version "1.5.3")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "ACD" version))
       (sha256
        (base32
         "1a67bi3hklq8nlc50r0qnyr4k7m9kpvijy8sqqpm54by5hsysfd6"))))
    (properties `((upstream-name . "ACD")))
    (build-system r-build-system)
    (home-page "https://cran.r-project.org/web/packages/ACD/")
    (synopsis "Categorical data analysis with complete or missing responses")
    (description
     "This package provides tools for categorical data analysis with complete
or missing responses.")
    (license license:gpl2+)))

(define-public r-acdm
  (package
    (name "r-acdm")
    (version "1.0.4")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "ACDm" version))
       (sha256
        (base32
         "0b4f02ga5ra66mbrm79g0bnlzmii82rks9kmxixxqgf18yhlyjil"))))
    (properties `((upstream-name . "ACDm")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-dplyr" ,r-dplyr)
       ("r-ggplot2" ,r-ggplot2)
       ("r-plyr" ,r-plyr)
       ("r-rsolnp" ,r-rsolnp)
       ("r-zoo" ,r-zoo)))
    (home-page "https://cran.r-project.org/web/packages/ACDm/")
    (synopsis "Tools for Autoregressive Conditional Duration Models")
    (description
     "ACDm is a package for Autoregressive Conditional Duration (ACD, Engle
and Russell, 1998) models.  It creates trade, price or volume durations from
transactions (tic) data, performs diurnal adjustments, fits various ACD models
and tests them.")
    (license license:gpl2+)))

(define-public r-overlap
  (package
    (name "r-overlap")
    (version "0.3.2")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "overlap" version))
       (sha256
        (base32
         "1j3m6ir1chdz0si2fhcw6gs7c9h09bv0chz18rpzxsywww6d4rzy"))))
    (build-system r-build-system)
    (home-page "https://cran.r-project.org/web/packages/overlap/")
    (synopsis "Estimates of coefficient of overlapping for animal activity patterns")
    (description
     "This package provides functions to fit kernel density functions to data
on temporal activity patterns of animals; estimate coefficients of overlapping
of densities for two species; and calculate bootstrap estimates of confidence
intervals.")
    (license license:gpl3+)))

(define-public r-snakecase
  (package
    (name "r-snakecase")
    (version "0.11.0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "snakecase" version))
       (sha256
        (base32
         "1ky1x2cp5rd0ffd9m1fji9sq4z4jsrpxzg30brw8bb4ihfjj114r"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-stringi" ,r-stringi)
       ("r-stringr" ,r-stringr)))
    (home-page "https://github.com/Tazinho/snakecase")
    (synopsis "Convert strings into any case")
    (description
     "This package provides a consistent, flexible and easy to use tool to
parse and convert strings into cases like snake or camel among others.")
    (license license:gpl3)))

(define-public r-prediction
  (package
    (name "r-prediction")
    (version "0.3.14")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "prediction" version))
       (sha256
        (base32
         "0awlq5lxfia6m2b91w73rksp93rbwv5gwqb36wbji4rgq41rzbrx"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-data-table" ,r-data-table)))
    (home-page "https://github.com/leeper/prediction")
    (synopsis "Tidy, type-safe prediction methods")
    (description
     "This package provides the @code{prediction()} function, a type-safe
alternative to @code{predict()} that always returns a data frame.  The package
currently supports common model types (e.g., @code{\"lm\"}, @code{\"glm\"})
from the @code{stats} package, as well as numerous other model classes from
other add-on packages.")
    (license license:expat)))

(define-public r-insight
  (package
    (name "r-insight")
    (version "0.8.2")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "insight" version))
       (sha256
        (base32
         "0fjf7dwpv1a7qfbzixppg348z1ksq19kdjm08vcb2am7w0k3plcj"))))
    (build-system r-build-system)
    (native-inputs
     `(("r-knitr" ,r-knitr)))
    (home-page "https://easystats.github.io/insight/")
    (synopsis "Easy access to model information for various model objects")
    (description
     "This package provides a tool to provide an easy, intuitive and
consistent access to information contained in various R models, like model
formulas, model terms, information about random effects, data that was used to
fit the model or data from response variables.  The package mainly revolves
around two types of functions: Functions that find (the names of) information,
starting with @code{find_}, and functions that get the underlying data,
starting with @code{get_}.  The package has a consistent syntax and works with
many different model objects, where otherwise functions to access these
information are missing.")
    (license license:gpl3)))

(define-public r-sjlabelled
  (package
    (name "r-sjlabelled")
    (version "1.1.3")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "sjlabelled" version))
       (sha256
        (base32
         "1amq7i9sxf0pkxhskqc53xq5wvc9rdxm7cxyb4b6xh6qsskjnlsj"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-haven" ,r-haven)
       ("r-insight" ,r-insight)))
    (home-page "https://github.com/strengejacke/sjlabelled")
    (synopsis "Labelled data utility functions")
    (description
     "This package provides a collection of functions dealing with labelled
data, like reading and writing data between R and other statistical software
packages.  This includes easy ways to get, set or change value and variable
label attributes, to convert labelled vectors into factors or numeric (and
vice versa), or to deal with multiple declared missing values.")
    (license license:gpl3)))

(define-public r-sjmisc
  (package
    (name "r-sjmisc")
    (version "2.8.3")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "sjmisc" version))
       (sha256
        (base32
         "0w8l9grmp4q775jrf4q6rxx36ld5daz9b0gdxyyh42xfihk6m62h"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-dplyr" ,r-dplyr)
       ("r-insight" ,r-insight)
       ("r-magrittr" ,r-magrittr)
       ("r-purrr" ,r-purrr)
       ("r-rlang" ,r-rlang)
       ("r-sjlabelled" ,r-sjlabelled)
       ("r-tidyselect" ,r-tidyselect)))
    (home-page "https://github.com/strengejacke/sjmisc")
    (synopsis "Data and variable transformation functions")
    (description
     "This package is a collection of miscellaneous utility functions,
supporting data transformation tasks like recoding, dichotomizing or grouping
variables, setting and replacing missing values.  The data transformation
functions also support labelled data, and all integrate seamlessly into a
tidyverse workflow.")
    (license license:gpl3)))

(define-public r-nortest
  (package
    (name "r-nortest")
    (version "1.0-4")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "nortest" version))
       (sha256
        (base32
         "17r0wpz72z9312c70nwi1i1kp1v9fm1h6jg7q5cx1mc1h420m1d3"))))
    (build-system r-build-system)
    (home-page "https://cran.r-project.org/web/packages/nortest/")
    (synopsis "Tests for normality")
    (description
     "This package provides five omnibus tests for testing the composite
hypothesis of normality.")
    (license license:gpl2+)))

(define-public r-moonbook
  (package
    (name "r-moonbook")
    (version "0.2.3")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "moonBook" version))
       (sha256
        (base32
         "0hys56mwbm776ff7dibi8wzyf69qiais9rs1jazv79lk6h56s9s6"))))
    (properties `((upstream-name . "moonBook")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-magrittr" ,r-magrittr)
       ("r-nortest" ,r-nortest)
       ("r-purrr" ,r-purrr)
       ("r-sjmisc" ,r-sjmisc)
       ("r-stringr" ,r-stringr)
       ("r-survival" ,r-survival)))
    (home-page "https://github.com/cardiomoon/moonBook")
    (synopsis "Functions and datasets for the book by Keon-Woong Moon")
    (description
     "This package provides several analysis-related functions for the book
entitled \"R statistics and graph for medical articles\" (written in Korean),
version 1, by Keon-Woong Moon with Korean demographic data with several plot
functions.")
    (license license:gpl2)))

(define-public r-flextable
  (package
    (name "r-flextable")
    (version "0.5.9")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "flextable" version))
       (sha256
        (base32
         "1rkz0nhwjy1l8sb0kmna5v492n2ydnk7gydswnmf88r8vfyjczhw"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-base64enc" ,r-base64enc)
       ("r-data-table" ,r-data-table)
       ("r-gdtools" ,r-gdtools)
       ("r-htmltools" ,r-htmltools)
       ("r-knitr" ,r-knitr)
       ("r-officer" ,r-officer)
       ("r-rlang" ,r-rlang)
       ("r-rmarkdown" ,r-rmarkdown)
       ("r-xml2" ,r-xml2)))
    (home-page "https://davidgohel.github.io/flextable")
    (synopsis "Functions for tabular reporting")
    (description
     "This package provides tools to create pretty tables for HTML documents
and other formats.  Functions are provided to let users create tables, modify
and format their content.  It extends the @code{officer} package and can be
used within R markdown documents when rendering to HTML and to Word
documents.")
    (license license:gpl3)))

(define-public r-writexl
  (package
    (name "r-writexl")
    (version "1.2")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "writexl" version))
       (sha256
        (base32
         "09fhdip6igcg97fjx4c7727cx2lb49l4d74l4i8rg2bag2s5lrj3"))))
    (build-system r-build-system)
    (inputs `(("zlib" ,zlib)))
    (home-page "https://github.com/ropensci/writexl")
    (synopsis "Export data frames to xlsx format")
    (description
     "This package provides a data frame to xlsx exporter based on
libxlsxwriter.")
    (license license:bsd-2)))

(define-public r-biasedurn
  (package
    (name "r-biasedurn")
    (version "1.07")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "BiasedUrn" version))
       (sha256
        (base32
         "13i2lgfnjhlbbm2yxfc2l5hswqw6x03pwba5csjmirv8kpjw4xr3"))))
    (properties `((upstream-name . "BiasedUrn")))
    (build-system r-build-system)
    (home-page "https://cran.r-project.org/web/packages/BiasedUrn/")
    (synopsis "Biased Urn model distributions")
    (description
     "This package provides statistical models of biased sampling in the form
of univariate and multivariate noncentral hypergeometric distributions,
including Wallenius' noncentral hypergeometric distribution and Fisher's
noncentral hypergeometric distribution (also called extended hypergeometric
distribution).")
    (license license:gpl3)))

(define-public r-goplot
  (package
    (name "r-goplot")
    (version "1.0.2")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "GOplot" version))
       (sha256
        (base32
         "1y8dv0kbzpr9za91njw0x233vx5d13vqml9hmpddcyi9s6va5nix"))))
    (properties `((upstream-name . "GOplot")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-ggdendro" ,r-ggdendro)
       ("r-ggplot2" ,r-ggplot2)
       ("r-gridextra" ,r-gridextra)
       ("r-rcolorbrewer" ,r-rcolorbrewer)))
    (home-page "https://github.com/wencke/wencke.github.io")
    (synopsis "Visualization of functional analysis data")
    (description
     "This package provides an implementation of multilayered visualizations
for enhanced graphical representation of functional analysis data.  It
combines and integrates omics data derived from expression and functional
annotation enrichment analyses.  Its plotting functions have been developed
with an hierarchical structure in mind: starting from a general overview to
identify the most enriched categories (modified bar plot, bubble plot) to a
more detailed one displaying different types of relevant information for the
molecules in a given set of categories (circle plot, chord plot, cluster plot,
Venn diagram, heatmap).")
    (license license:gpl2)))

(define-public r-getopt
  (package
    (name "r-getopt")
    (version "1.20.3")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "getopt" version))
       (sha256
        (base32
         "0zzmzgwl9a4y3s34600vmih22d6y32294f9bvxrnmffnvkgmy7sk"))))
    (build-system r-build-system)
    (home-page "https://github.com/trevorld/getopt")
    (synopsis "Command-line option processor for R")
    (description
     "This package is designed to be used with Rscript to write shebang
scripts that accept short and long options.  Many users will prefer to
use the packages @code{optparse} or @code{argparse} which add extra
features like automatically generated help options and usage texts,
support for default values, positional argument support, etc.")
    (license license:gpl2+)))

(define-public r-findpython
  (package
    (name "r-findpython")
    (version "1.0.5")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "findpython" version))
       (sha256
        (base32
         "0icifm4z6hhpmcjrg75a875iph0ci890ss02kdv3725pijc236iy"))))
    (build-system r-build-system)
    (home-page "https://github.com/trevorld/findpython")
    (synopsis "Functions to find an acceptable Python binary")
    (description
     "This package was designed to find an acceptable Python binary that
matches version and feature constraints.")
    (license license:expat)))

;; This in not the same as "r-argparser"
(define-public r-argparse
  (package
    (name "r-argparse")
    (version "2.0.1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "argparse" version))
       (sha256
        (base32
         "1as7h6z7kzgv0fqzpnp76qbm96b4jcd37azd58b7rz0l1n94764l"))))
    (build-system r-build-system)
    (inputs `(("python" ,python)))
    (propagated-inputs
     `(("r-findpython" ,r-findpython)
       ("r-jsonlite" ,r-jsonlite)
       ("r-r6" ,r-r6)))
    (home-page "https://github.com/trevorld/argparse")
    (synopsis "Command line optional and positional argument parser")
    (description
     "This package provides a command line parser to be used with Rscript to
write shebang scripts that gracefully accept positional and optional arguments
and automatically generate usage notices.")
    (license license:gpl2+)))

(define-public r-hash
  (package
    (name "r-hash")
    (version "2.2.6.1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "hash" version))
       (sha256
        (base32
         "0b3fl0rvgwb992knl81vm99lsldg5clvaqjh6mamm6zqmb6dz056"))))
    (build-system r-build-system)
    (home-page "https://cran.r-project.org/web/packages/hash/")
    (synopsis "Implementation of hash/associated arrays/dictionaries")
    (description
     "This package implements a data structure similar to hashes in Perl and
dictionaries in Python but with a purposefully R flavor.  For objects of
appreciable size, access using hashes outperforms native named lists and
vectors.")
    (license license:gpl2+)))

(define-public r-orddom
  (package
    (name "r-orddom")
    (version "3.1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "orddom" version))
       (sha256
        (base32
         "165axs15fvwhrp89xd87l81q3h2qjll1vrwcsap645cwvb85nwsh"))))
    (build-system r-build-system)
    (propagated-inputs `(("r-psych" ,r-psych)))
    (home-page "https://cran.r-project.org/web/packages/orddom/")
    (synopsis "Ordinal dominance statistics")
    (description
     "This package provides tools to compute ordinal, statistics and effect
sizes as an alternative to mean comparison: Cliff's delta or success rate
difference (SRD), Vargha and Delaney's A or the Area Under a Receiver
Operating Characteristic Curve (AUC), the discrete type of McGraw & Wong's
Common Language Effect Size (CLES) or Grissom & Kim's Probability of
Superiority (PS), and the Number needed to treat (NNT) effect size.  Moreover,
comparisons to Cohen's d are offered based on Huberty & Lowman's Percentage of
Group (Non-)Overlap considerations.")
    (license license:gpl2)))

(define-public r-deriv
  (package
    (name "r-deriv")
    (version "4.0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "Deriv" version))
       (sha256
        (base32
         "03mlfy8jzzzbh2l18gnmw0a71n9savx4cw72yhkxq93v2xj8fy3n"))))
    (properties `((upstream-name . "Deriv")))
    (build-system r-build-system)
    (home-page "https://cran.r-project.org/web/packages/Deriv")
    (synopsis "Symbolic differentiation")
    (description
     "This package provides an R-based solution for symbolic differentiation.
It admits user-defined functions as well as function substitution in arguments
of functions to be differentiated.  Some symbolic simplification is part of
the work.")
    (license license:gpl3+)))

(define-public r-doby
  (package
    (name "r-doby")
    (version "4.6.5")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "doBy" version))
       (sha256
        (base32
         "1ckazh701b4ilg8bj17ji903538jmb49d997gm49ah5j5jc1x0g7"))))
    (properties `((upstream-name . "doBy")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-broom" ,r-broom)
       ("r-deriv" ,r-deriv)
       ("r-dplyr" ,r-dplyr)
       ("r-magrittr" ,r-magrittr)
       ("r-mass" ,r-mass)
       ("r-matrix" ,r-matrix)
       ("r-plyr" ,r-plyr)
       ("r-pbkrtest" ,r-pbkrtest)
       ("r-tibble" ,r-tibble)))
    (home-page "http://people.math.aau.dk/~sorenh/software/doBy/")
    (synopsis "Groupwise statistics, LSmeans, linear contrasts, and utilities")
    (description
     "This package contains:

@itemize
@item facilities for working with grouped data: @code{do}
  something to data stratified @code{by} some variables.
@item implementations of least-squares means, general linear contrasts, and
@item miscellaneous other utilities.
@end itemize\n")
    (license license:gpl2+)))

(define-public r-refgenome
  (package
    (name "r-refgenome")
    (version "1.7.7")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "refGenome" version))
       (sha256
        (base32
         "1za89bn3am1zgvm641qi1ab6kaqpll4rb9p9f1sjwvcgqq6065g5"))))
    (properties `((upstream-name . "refGenome")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-dbi" ,r-dbi)
       ("r-doby" ,r-doby)
       ("r-rsqlite" ,r-rsqlite)))
    (home-page "https://cran.r-project.org/web/packages/refGenome/")
    (synopsis
     "Gene and splice site annotation using annotation data from Ensembl and UCSC")
    (description
     "This package contains functionality for importing and managing of
downloaded genome annotation data from the Ensembl genome browser (European
Bioinformatics Institute) and from the UCSC genome browser (University of
California, Santa Cruz) and annotation routines for genomic positions and
splice site positions.")
    (license license:gpl2)))

(define-public r-basix
  (package
    (name "r-basix")
    (version "1.1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "BASIX" version))
       (sha256
        (base32
         "18dkvv1iwskfnlpl6xridcgqpalbbpm2616mvc3hfrc0b26v01id"))))
    (properties `((upstream-name . "BASIX")))
    (build-system r-build-system)
    (home-page "https://cran.r-project.org/web/packages/BASIX/")
    (synopsis "Efficient C/C++ toolset for R")
    (description
     "BASIX provides some efficient C/C++ implementations of native R
procedures to speed up calculations in R.")
    (license license:gpl2)))

(define-public r-blockfest
  (package
    (name "r-blockfest")
    (version "1.6")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "BlockFeST" version))
       (sha256
        (base32
         "0hj7a5as7nxbgjac7lbj6qfwffx3g8x8phpf9a55f1c9cdzi73a5"))))
    (properties `((upstream-name . "BlockFeST")))
    (build-system r-build-system)
    (propagated-inputs `(("r-basix" ,r-basix)))
    (home-page "https://cran.r-project.org/web/packages/BlockFeST/")
    (synopsis "Bayesian calculation of region-specific fixation index")
    (description
     "This package provides an R implementation of an extension of the
BayeScan software for codominant markers, adding the option to group
individual SNPs into pre-defined blocks.  A typical application of this new
approach is the identification of genomic regions, genes, or gene sets
containing one or more SNPs that evolved under directional selection.")
    (license license:gpl2)))

(define-public r-proc
  (package
    (name "r-proc")
    (version "1.16.2")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "pROC" version))
       (sha256
        (base32
         "0apwa5zzqh74pjnvf5a1s5qf6i9r5h44jdllfrwymkd2v479d2xn"))))
    (properties `((upstream-name . "pROC")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-plyr" ,r-plyr)
       ("r-rcpp" ,r-rcpp)))
    (home-page "https://web.expasy.org/pROC/")
    (synopsis "Display and analyze ROC curves")
    (description
     "This package provides tools for visualizing, smoothing and comparing
receiver operating characteristic (ROC curves).  The area under the
curve (AUC) can be compared with statistical tests based on U-statistics or
bootstrap.  Confidence intervals can be computed for (p)AUC or ROC curves.")
    (license license:gpl3+)))

(define-public r-rootsolve
  (package
    (name "r-rootsolve")
    (version "1.8.2")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "rootSolve" version))
       (sha256
        (base32
         "0rj7c4zcrzgz7sb0vgvh7swpfafnw4040cxp7ypas3s8fnihn54l"))))
    (properties `((upstream-name . "rootSolve")))
    (build-system r-build-system)
    (native-inputs `(("gfortran" ,gfortran)))
    (home-page "https://cran.r-project.org/web/packages/rootSolve/")
    (synopsis "Tools for the analysis of ordinary differential equations")
    (description
     "This package provides routines to find the root of nonlinear functions,
and to perform steady-state and equilibrium analysis of @dfn{ordinary
differential equations} (ODE).  It includes routines that:

@enumerate
@item generate gradient and jacobian matrices (full and banded),
@item find roots of non-linear equations by the Newton-Raphson method,
@item estimate steady-state conditions of a system of (differential) equations
  in full, banded or sparse form, using the Newton-Raphson method, or by
  dynamically running,
@item solve the steady-state conditions for uni- and multicomponent 1-D, 2-D,
  and 3-D partial differential equations, that have been converted to ordinary
  differential equations by numerical differencing (using the method-of-lines
  approach).
@end enumerate\n")
    (license license:gpl2+)))

(define-public r-abcanalysis
  (package
    (name "r-abcanalysis")
    (version "1.2.1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "ABCanalysis" version))
       (sha256
        (base32 "0wac1ksmnxa36v99ca4hv8k0rsh3igwpcllmlv9wf7i9kgqviqwi"))))
    (properties `((upstream-name . "ABCanalysis")))
    (build-system r-build-system)
    (propagated-inputs `(("r-plotrix" ,r-plotrix)))
    (home-page "https://www.uni-marburg.de/fb12/arbeitsgruppen/datenbionik/software-en/")
    (synopsis "Computed ABC Analysis")
    (description
     "Multivariate data sets often differ in several factors or derived statistical
parameters, which have to be selected for a valid interpretation.  Basing this
selection on traditional statistical limits leads occasionally to the perception
of losing information from a data set.  This package provides tools to calculate
these limits on the basis of the mathematical properties of the distribution of
the analyzed items.")
    (license license:gpl3)))

(define-public r-slam
  (package
    (name "r-slam")
    (version "0.1-47")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "slam" version))
       (sha256
        (base32 "12fggw2c7hz3bpvsaqm24g3r6lbpq6jgli24g7x5j859iak5cqv9"))))
    (build-system r-build-system)
    (home-page "https://cran.r-project.org/web/packages/slam/")
    (synopsis "Sparse lightweight arrays and matrices")
    (description
     "This package contains data structures and algorithms for sparse arrays and matrices,
based on index arrays and simple triplet representations, respectively.")
    (license license:gpl2)))

(define-public r-manipulatewidget
  (package
    (name "r-manipulatewidget")
    (version "0.10.1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "manipulateWidget" version))
       (sha256
        (base32 "1vi71sjh7z1a880wffk8qqw7iysvk42q78giqxmm2sqz2a912qlx"))))
    (properties
     `((upstream-name . "manipulateWidget")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-base64enc" ,r-base64enc)
       ("r-codetools" ,r-codetools)
       ("r-htmltools" ,r-htmltools)
       ("r-htmlwidgets" ,r-htmlwidgets)
       ("r-knitr" ,r-knitr)
       ("r-miniui" ,r-miniui)
       ("r-shiny" ,r-shiny)
       ("r-webshot" ,r-webshot)))
    (home-page "https://github.com/rte-antares-rpackage/manipulateWidget/")
    (synopsis "Add even more interactivity to interactive charts")
    (description
     "This package lets you create in just a few lines of R code a nice user interface to
modify the data or the graphical parameters of one or multiple interactive
charts.  It is useful to quickly explore visually some data or for package
developers to generate user interfaces easy to maintain.")
    (license license:gpl2+)))

(define-public r-a3
  (package
    (name "r-a3")
    (version "1.0.0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "A3" version))
       (sha256
        (base32 "017hq9pjsv1h9i7cqk5cfx27as54shlhdsdvr6jkhb8jfkpdb6cw"))))
    (properties `((upstream-name . "A3")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-pbapply" ,r-pbapply)
       ("r-xtable" ,r-xtable)))
    (home-page "https://cran.r-project.org/web/packages/A3/")
    (synopsis "Error metrics for predictive models")
    (description
     "This package supplies tools for tabulating and analyzing the results of predictive
models.  The methods employed are applicable to virtually any predictive model
and make comparisons between different methodologies straightforward.")
    (license license:gpl2+)))

(define-public r-infotheo
  (package
    (name "r-infotheo")
    (version "1.2.0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "infotheo" version))
       (sha256
        (base32
         "18xacczfq3z3xpy434js4nf3l19lczngzd0lq26wh22pvg1yniwv"))))
    (build-system r-build-system)
    (home-page "http://homepage.meyerp.com/software")
    (synopsis "Information-theoretic measures")
    (description
     "This package implements various measures of information theory based on
several entropy estimators.")
    (license license:gpl3+)))

(define-public r-abcoptim
  (package
    (name "r-abcoptim")
    (version "0.15.0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "ABCoptim" version))
       (sha256
        (base32 "1ih0xk88qhsmpvnxf56041wx5sk8as2f4f2gdnpnwdym9mbr9n4b"))))
    (properties `((upstream-name . "ABCoptim")))
    (build-system r-build-system)
    (propagated-inputs `(("r-rcpp" ,r-rcpp)))
    (home-page "https://github.com/gvegayon/ABCoptim/")
    (synopsis "Optimization of Artificial Bee Colony algorithm")
    (description
     "Artificial Bee Colony (ABC) is one of the most recently defined algorithms by Dervis
Karaboga in 2005, motivated by the intelligent behavior of honey bees.  It is as
simple as Particle Swarm Optimization (PSO) and Differential Evolution (DE)
algorithms, and uses only common control parameters such as colony size and
maximum cycle number.  The @code{r-abcoptim} implements the Artificial bee
colony optimization algorithm @url{http://mf.erciyes.edu.tr/abc/pub/tr06_2005.pdf}.
  This version is a work-in-progress and is written in R code.")
    (license license:expat)))

(define-public r-abcp2
  (package
    (name "r-abcp2")
    (version "1.2")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "ABCp2" version))
       (sha256
        (base32 "1s2skkxpzss7c29i8600psgrp0hl46jcrxqrmy2b4db8hc0kcnbx"))))
    (properties `((upstream-name . "ABCp2")))
    (build-system r-build-system)
    (propagated-inputs `(("r-mass" ,r-mass)))
    (home-page "https://cran.r-project.org/web/packages/ABCp2/")
    (synopsis "Approximate Bayesian Computational Model for Estimating P2")
    (description
     "This package tests the goodness of fit of a distribution of offspring to the Normal,
Poisson, and Gamma distribution and estimates the proportional paternity of the
second male (P2) based on the best fit distribution.")
    (license license:gpl2)))

(define-public r-abcrf
  (package
    (name "r-abcrf")
    (version "1.8.1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "abcrf" version))
       (sha256
        (base32 "1ghbd24yhqy3xhdxas6ccn84nkavqpgldx5ck8kijknc7qjm8k27"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-doparallel" ,r-doparallel)
       ("r-foreach" ,r-foreach)
       ("r-mass" ,r-mass)
       ("r-matrixstats" ,r-matrixstats)
       ("r-ranger" ,r-ranger)
       ("r-rcpp" ,r-rcpp)
       ("r-rcpparmadillo" ,r-rcpparmadillo)
       ("r-readr" ,r-readr)
       ("r-stringr" ,r-stringr)))
    (home-page "https://cran.r-project.org/web/packages/abcrf/")
    (synopsis "Approximate bayesian computation via random forests")
    (description
     "This package performs approximate bayesian computation (ABC) model choice and
parameter inference via random forests.  This machine learning tool named random
forests (RF) can conduct selection among the highly complex models covered by
ABC algorithms.")
    (license license:gpl2+)))

(define-public r-abctools
  (package
    (name "r-abctools")
    (version "1.1.3")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "abctools" version))
       (sha256
        (base32 "07s9dg10i8lsxl73b4n2hynca2fjgb0ykb0dz8c3zv6cgw3cyx97"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-abc" ,r-abc)
       ("r-abind" ,r-abind)
       ("r-hmisc" ,r-hmisc)
       ("r-plyr" ,r-plyr)))
    (home-page "https://github.com/dennisprangle/abctools/")
    (synopsis "Tools for ABC analyses")
    (description
     "This @code{r-abctools} package provides tools for approximate Bayesian computation
including summary statistic selection and assessing coverage.  This includes
recent dimension reduction algorithms to tune the choice of summary statistics,
and coverage methods to tune the choice of threshold.")
    (license license:gpl2+)))

(define-public r-ggstance
  (package
    (name "r-ggstance")
    (version "0.3.4")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "ggstance" version))
       (sha256
        (base32 "0aqz3dn02cgij018a4sglqwrwr9dzzj12l8xr1064q7hfd4f64m1"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-ggplot2" ,r-ggplot2)
       ("r-plyr" ,r-plyr)
       ("r-rlang" ,r-rlang)
       ("r-withr" ,r-withr)))
    (home-page "https://cran.r-project.org/web/packages/ggstance/")
    (synopsis "Horizontal and vertical versions of @code{r-ggplot2}")
    (description
     "This package is a @code{r-ggplot2} extension that provides flipped components:
@enumerate
@item horizontal versions of @code{r-ggplot2} stats and @code{r-ggplot2} geoms;
@item vertical versions of @code{r-ggplot2} positions.
@end enumerate")
    (license license:gpl3)))

(define-public r-mosaiccore
  (package
    (name "r-mosaiccore")
    (version "0.6.0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "mosaicCore" version))
       (sha256
        (base32 "1klw97h6lchw1cpcl8s637ikcl428cckmjq0czi7mibh9q9mw72z"))))
    (properties `((upstream-name . "mosaicCore")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-dplyr" ,r-dplyr)
       ("r-lazyeval" ,r-lazyeval)
       ("r-mass" ,r-mass)
       ("r-rlang" ,r-rlang)
       ("r-tidyr" ,r-tidyr)))
    (home-page "https://github.com/ProjectMOSAIC/mosaicCore/")
    (synopsis "Common utilities for mosaic family packages")
    (description
     "Common utilities used in other Mosaic family packages are collected here.")
    (license license:gpl2+)))

(define-public r-ggformula
  (package
    (name "r-ggformula")
    (version "0.9.4")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "ggformula" version))
       (sha256
        (base32 "04vdhg1bbc1psrx9ggaphz7cx4fw5xsmhkqpqfcg2w4ba2bjy46f"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-ggforce" ,r-ggforce)
       ("r-ggplot2" ,r-ggplot2)
       ("r-ggstance" ,r-ggstance)
       ("r-magrittr" ,r-magrittr)
       ("r-mosaiccore" ,r-mosaiccore)
       ("r-rlang" ,r-rlang)
       ("r-stringr" ,r-stringr)
       ("r-tibble" ,r-tibble)))
    (home-page "https://github.com/ProjectMOSAIC/ggformula/")
    (synopsis "Formula interface for the @code{r-ggplot2}")
    (description
     "The @code{r-ggformula} introduces a family of graphics functions, gf_point(),
gf_density(), and so on, bring the formula interface to ggplot().  This captures
and extends the excellent simplicity of the lattice-graphics formula interface,
while providing the intuitive capabilities of @code{r-ggplot2}.")
    (license license:expat)))

(define-public r-mosaicdata
  (package
    (name "r-mosaicdata")
    (version "0.17.0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "mosaicData" version))
       (sha256
        (base32 "04z0mdm52mykqsxsinhmsihn181zf6cw321gayk2rjp7lj7mwdq9"))))
    (properties `((upstream-name . "mosaicData")))
    (build-system r-build-system)
    (home-page "https://cran.r-project.org/web/packages/mosaicData/")
    (synopsis "Data sets for project Mosaic")
    (description
     "This package provides data sets from project Mosaic @url{http://mosaic-web.org}
used to teach mathematics, statistics, computation and modeling.")
    (license license:gpl2+)))

(define-public r-raster
  (package
    (name "r-raster")
    (version "3.0-12")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "raster" version))
       (sha256
        (base32
         "0rrbsigkqxsdic8fly6nrsc79zsliwvr1x2b4xqpl9d34vr50dvg"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-rcpp" ,r-rcpp)
       ("r-sp" ,r-sp)))
    (home-page "https://www.rspatial.org/")
    (synopsis "Geographic data analysis and modeling")
    (description
     "The package implements basic and high-level functions for reading,
writing, manipulating, analyzing and modeling of gridded spatial data.
Processing of very large files is supported.")
    (license license:gpl3+)))

(define-public r-mosaic
  (package
   (name "r-mosaic")
   (version "1.4.0")
   (source
    (origin
     (method url-fetch)
     (uri (cran-uri "mosaic" version))
     (sha256
      (base32 "10jbrg8kli00kfgbh2f67bymm5cnlancc9dplb1j7fl552yjddn2"))))
   (build-system r-build-system)
   (propagated-inputs
    `(("r-broom" ,r-broom)
      ("r-dplyr" ,r-dplyr)
      ("r-ggdendro" ,r-ggdendro)
      ("r-ggformula" ,r-ggformula)
      ("r-ggplot2" ,r-ggplot2)
      ("r-ggrepel" ,r-ggrepel)
      ("r-glue" ,r-glue)
      ("r-gridextra" ,r-gridextra)
      ("r-lattice" ,r-lattice)
      ("r-latticeextra" ,r-latticeextra)
      ("r-lazyeval" ,r-lazyeval)
      ("r-mass" ,r-mass)
      ("r-matrix" ,r-matrix)
      ("r-mosaiccore" ,r-mosaiccore)
      ("r-mosaicdata" ,r-mosaicdata)
      ("r-readr" ,r-readr)
      ("r-tidyr" ,r-tidyr)))
   (native-inputs
    `(("r-knitr" ,r-knitr)))
   (home-page "https://github.com/ProjectMOSAIC/mosaic/")
   (synopsis "Mathematics, statistics, and computation teaching utilities")
   (description
    "This package contain data sets and utilities from
@url{http://mosaic-web.org, Project MOSAIC} used to teach mathematics,
statistics, computation and modeling.  Project MOSAIC is a community of
educators working to tie together aspects of quantitative work that students
in science, technology, engineering and mathematics will need in their
professional lives, but which are usually taught in isolation, if at all.")
   (license license:gpl2+)))

(define-public r-abd
  (package
    (name "r-abd")
    (version "0.2-8")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "abd" version))
       (sha256
        (base32 "191gspqzdv573vaw624ri0f5cm6v4j524bjs74d4a1hn3kn6r9b7"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-lattice" ,r-lattice)
       ("r-mosaic" ,r-mosaic)
       ("r-nlme" ,r-nlme)))
    (home-page "https://cran.r-project.org/web/packages/abd/")
    (synopsis "Analysis of biological data")
    (description
     "The @code{r-abd} package contains data sets and sample code for the Analysis of
biological data by Michael Whitlock and Dolph Schluter.")
    (license license:gpl2)))

(define-public r-svgui
  (package
    (name "r-svgui")
    (version "1.0.0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "svGUI" version))
       (sha256
        (base32 "1r7ab0p4yr8q03gj02hmj7k1ghksgkg4nx750c0ajfs2q9y1dxfc"))))
    (properties `((upstream-name . "svGUI")))
    (build-system r-build-system)
    (home-page "https://github.com/SciViews/svGUI/")
    (synopsis "Functions for managing GUI clients in R")
    (description
     "The SciViews @code{svGUI} package eases the management of Graphical User
Interfaces (GUI) in R.  It is independent from any particular GUI widgets.  It
centralizes info about GUI elements currently used, and it dispatches GUI
calls to the particular toolkits in use in function of the context.")
    (license license:gpl2)))

(define-public r-svdialogs
  (package
    (name "r-svdialogs")
    (version "1.0.0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "svDialogs" version))
       (sha256
        (base32 "0xqppydfawnwk84kb5qiybwbcmv38vn4imgz01mz2pnq4xb80p97"))))
    (properties `((upstream-name . "svDialogs")))
    (build-system r-build-system)
    (inputs
     `(("yad" ,yad)
       ("zenity" ,zenity)))
    (propagated-inputs
     `(("r-rstudioapi" ,r-rstudioapi)
       ("r-svgui" ,r-svgui)))
    (home-page "https://github.com/SciViews/svDialogs/")
    (synopsis "Portable dialog boxes")
    (description
     "This package helps to construct standard dialog boxes for your GUI, including
message boxes, input boxes, list, file or directory selection, and others.  In
case R cannot display GUI dialog boxes, a simpler command line version of these
interactive elements is also provided as a fallback solution.")
    (license license:gpl2)))

(define-public r-abe
  (package
    (name "r-abe")
    (version "3.0.1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "abe" version))
       (sha256
        (base32
         "1f19h3xzzmjhvwc1rrb8z0rai3ip03y4gdi2gg9bfr5sg2nfklk6"))))
    (build-system r-build-system)
    (home-page "https://cran.r-project.org/web/packages/abe/")
    (synopsis "Augmented backward elimination")
    (description
     "This package performs augmented backward elimination and checks the
stability of the obtained model.  Augmented backward elimination combines
significance or information based criteria with the change in estimate to
either select the optimal model for prediction purposes or to serve as a tool
to obtain a practically sound, highly interpretable model.")
    (license license:gpl2+)))

(define-public r-abf2
  (package
    (name "r-abf2")
    (version "0.7-1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "abf2" version))
       (sha256
        (base32 "0d65mc1w4pbiv7xaqzdlw1bfsxf25587rv597hh41vs0j0zlfpxx"))))
    (build-system r-build-system)
    (home-page "https://cran.r-project.org/web/packages/abf2/")
    (synopsis "Load gap-free axon @code{r-abf2} files")
    (description
     "This package loads electrophysiology data from ABF2 files, as created by
Axon Instruments/Molecular Devices software.  Only files recorded in gap-free
mode are currently supported.")
    (license license:artistic2.0)))

(define-public r-abhgenotyper
  (package
    (name "r-abhgenotyper")
    (version "1.0.1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "ABHgenotypeR" version))
       (sha256
        (base32 "08cpmnaaxsm5c5bjifnfxdlvg5inrf13biqpcl2yq5zpqjmiki0l"))))
    (properties `((upstream-name . "ABHgenotypeR")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-ggplot2" ,r-ggplot2)
       ("r-reshape2" ,r-reshape2)))
    (home-page "https://github.com/StefanReuscher/ABHgenotypeR/")
    (synopsis "Visualize and manipulate ABH genotypes")
    (description
     "The @code{r-abhgenotyper} package provides simple imputation,
error-correction and plotting capacities for genotype data.  The package is
supposed to serve as an intermediate but independent analysis tool between the
TASSEL GBS pipeline and the @code{r-qtl} package.  It provides functionalities
not found in either TASSEL or @code{r-qtl} in addition to visualization of
genotypes as \"graphical genotypes\".")
    (license license:gpl3)))

(define-public r-furrr
  (package
    (name "r-furrr")
    (version "0.1.0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "furrr" version))
       (sha256
        (base32
         "1ld9aa9hydna94hgm6p91zjbfv1dz1vsgchjlpknkg6irbvkfafx"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-future" ,r-future)
       ("r-globals" ,r-globals)
       ("r-purrr" ,r-purrr)
       ("r-rlang" ,r-rlang)))
    (home-page "https://github.com/DavisVaughan/furrr")
    (synopsis "Apply mapping functions in parallel using futures")
    (description
     "This package provides implementations of the family of @code{map()}
functions from the @code{purrr} package that can be resolved using any
@code{future}-supported backend, e.g. parallel on the local machine or
distributed on a compute cluster.")
    (license license:lgpl2.1+)))

(define-public r-abjutils
  (package
    (name "r-abjutils")
    (version "0.2.3")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "abjutils" version))
       (sha256
        (base32 "0n4zps65y3zg0gfzlv97w91si52a9izkncirskbkj5x9hk0nhxcv"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-devtools" ,r-devtools)
       ("r-dplyr" ,r-dplyr)
       ("r-furrr" ,r-furrr)
       ("r-future" ,r-future)
       ("r-glue" ,r-glue)
       ("r-httr" ,r-httr)
       ("r-magrittr" ,r-magrittr)
       ("r-progress" ,r-progress)
       ("r-purrr" ,r-purrr)
       ("r-readr" ,r-readr)
       ("r-rlang" ,r-rlang)
       ("r-rstudioapi" ,r-rstudioapi)
       ("r-scales" ,r-scales)
       ("r-stringi" ,r-stringi)
       ("r-stringr" ,r-stringr)
       ("r-tibble" ,r-tibble)
       ("r-tidyr" ,r-tidyr)))
    (home-page "https://github.com/abjur/abjutils/")
    (synopsis "Collection of tools for jurimetrical analysis")
    (description
     "This package implements general purpose tools, such as functions for
sampling and basic manipulation of Brazilian lawsuits identification number.
It also implements functions for text cleaning, such as accentuation
removal.")
    (license license:expat)))

(define-public r-abnormality
  (package
    (name "r-abnormality")
    (version "0.1.0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "abnormality" version))
       (sha256
        (base32 "1fzfskl9akl06nliy8hkv2a0pznpj8pwcypg3gj5r2nzvr3kan9v"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-mass" ,r-mass)
       ("r-matrix" ,r-matrix)))
    (home-page "https://cran.r-project.org/web/packages/abnormality/")
    (synopsis "Measure a subject's abnormality with respect to a reference population")
    (description
     "This package contains functions to implement the methodology and
considerations laid out by Marks et al. in the article \"Measuring abnormality
in high dimensional spaces: applications in biomechanical gait analysis\".
Using high-dimensional datasets to measure a subject's overall level of
abnormality as compared to a reference population is often needed in outcomes
research.")
    (license license:expat)))

(define-public r-abodoutlier
  (package
    (name "r-abodoutlier")
    (version "0.1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "abodOutlier" version))
       (sha256
        (base32 "1pvhgxmh23br84r0fbmv7g53z2427birdja96a67vqgz18r3fdvj"))))
    (properties `((upstream-name . "abodOutlier")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-cluster" ,r-cluster)))
    (home-page "https://cran.r-project.org/web/packages/abodOutlier/")
    (synopsis "Angle-based outlier detection")
    (description
     "This package performs angle-based outlier detection on a given data
frame.  It offers three methods to process data:
@enumerate
@item full but slow implementation using all the data that has cubic
  complexity;
@item a fully randomized method;
@item a method using k-nearest neighbours.
@end enumerate
These algorithms are well suited for high dimensional data outlier
detection.")
    (license license:expat)))

(define-public r-abps
  (package
    (name "r-abps")
    (version "0.3")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "ABPS" version))
       (sha256
        (base32 "0n3f66nmfi5v94il1mxy026mi84w01ph2aljk60vn3mrz8kwf2ll"))))
    (properties `((upstream-name . "ABPS")))
    (build-system r-build-system)
    (propagated-inputs `(("r-kernlab" ,r-kernlab)))
    (home-page "https://cran.r-project.org/web/packages/ABPS/")
    (synopsis "Abnormal blood profile score to detect blood doping")
    (description
     "This package offers an implementation of the @dfn{Abnormal blood profile score} (ABPS).
The ABPS is a part of the Athlete biological passport program of the World
anti-doping agency, which combines several blood parameters into a single
score in order to detect blood doping.  The package also contains functions to
calculate other scores used in anti-doping programs, such as the ratio of
hemoglobin to reticulocytes (OFF-score), as well as example data.")
    (license license:gpl2+)))

(define-public r-parmigene
  (package
    (name "r-parmigene")
    (version "1.0.2")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "parmigene" version))
       (sha256
        (base32
         "1fsm6pkr17jcbzkj1hbn91jf890fviqk1lq6ls8pihsdgah1zb4d"))))
    (build-system r-build-system)
    (home-page "https://cran.r-project.org/web/packages/parmigene/")
    (synopsis "Mutual information estimation for gene network reconstruction")
    (description
     "This package provides a parallel estimation of the mutual information
based on entropy estimates from k-nearest neighbors distances and algorithms
for the reconstruction of gene regulatory networks.")
    (license license:agpl3+)))

(define-public r-pscl
  (package
    (name "r-pscl")
    (version "1.5.5")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "pscl" version))
       (sha256
        (base32 "0vzf5wazs92bhqhqd66v3vwmbfmnh67gb2466g1xxawim649nk05"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-mass" ,r-mass)))
    (home-page "https://github.com/atahk/pscl/")
    (synopsis "Political science computational laboratory")
    (description
     "The @code{pscl} is an R package providing classes and methods for:
@enumerate
@item Bayesian analysis of roll call data (item-response models);
@item elementary Bayesian statistics;
@item maximum likelihood estimation of zero-inflated and hurdle models for count
data;
@item utility functions.
@end enumerate")
    (license license:gpl2)))

(define-public r-accelmissing
  (package
    (name "r-accelmissing")
    (version "1.4")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "accelmissing" version))
       (sha256
        (base32 "1nql9inx6azdzi3z4sfm2vdml2mms6krl8wzlf1dn1c97ahn57fy"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-mice" ,r-mice)
       ("r-pscl" ,r-pscl)))
    (home-page "https://cran.r-project.org/web/packages/accelmissing/")
    (synopsis "Missing value imputation for accelerometer data")
    (description
     "This package provides a statistical method to impute the missing values in
accelerometer data.  The methodology includes both parametric and
semi-parametric multiple imputations under the zero-inflated Poisson lognormal
model.  It also provides multiple functions to preprocess the accelerometer data
previous to the missing data imputation.  These include detecting the wearing
and the non-wearing time, selecting valid days and subjects, and creating plots.")
    (license license:gpl2+)))

(define-public r-mhsmm
  (package
    (name "r-mhsmm")
    (version "0.4.16")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "mhsmm" version))
       (sha256
        (base32 "009dj0zkj1zry7jr9hf4cknb686z50a2l967if64xm0dvjmp7dgs"))))
    (build-system r-build-system)
    (propagated-inputs `(("r-mvtnorm" ,r-mvtnorm)))
    (home-page "https://github.com/jaredo/mhsmm/")
    (synopsis "Inference for hidden Markov and semi-Markov models")
    (description
     "The @code{r-mhsmm} package implements estimation and prediction methods for
hidden Markov and semi-Markov models for multiple observation sequences.  Such
techniques are of interest when observed data is thought to be dependent on some
unobserved (or hidden) state.  Also, this package is suitable for equidistant
time series data, with multivariate and/or missing data.  Allows user defined
emission distributions.")
    (license license:gpl2+)))

(define-public r-nleqslv
  (package
    (name "r-nleqslv")
    (version "3.3.2")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "nleqslv" version))
       (sha256
        (base32 "1v9znvncyigw9r25wx2ma0b7ib179b488dl0qsrhp5zrcz7mcjgm"))))
    (build-system r-build-system)
    (native-inputs `(("gfortran" ,gfortran)))
    (home-page "https://cran.r-project.org/web/packages/nleqslv/")
    (synopsis "Solve systems of nonlinear equations")
    (description
     "The @code{r-nleqslv} package solves a system of nonlinear equations using a
Broyden or a Newton method with a choice of global strategies such as line
search and trust region.  There are options for using a numerical or user
supplied Jacobian, for specifying a banded numerical Jacobian and for allowing a
singular or ill-conditioned Jacobian.")
    (license license:gpl2+)))

(define-public r-physicalactivity
  (package
    (name "r-physicalactivity")
    (version "0.2-2")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "PhysicalActivity" version))
       (sha256
        (base32 "14z6plgwyr46vs9m997rvlz8sdglfs9g087an8668zqkzzs2w4ln"))))
    (properties
     `((upstream-name . "PhysicalActivity")))
    (build-system r-build-system)
    (home-page "https://cran.r-project.org/web/packages/PhysicalActivity/")
    (synopsis "Procesing accelerometer data for physical activity measurement")
    (description
     "This @code{r-physicalactivity} package provides a function @code{wearingMarking}
for classification of monitor wear and nonwear time intervals in accelerometer
data collected to assess physical activity.  The package also contains functions
for making plots of accelerometer data and obtaining the summary of various
information including daily monitor wear time and the mean monitor wear time
during valid days.  The revised package version 0.2-1 improved the functions
regarding speed, robustness and add better support for time zones and daylight
saving.  In addition, several functions were added:
@enumerate
@item the @code{markDelivery} can classify days for ActiGraph delivery by mail;
@item the @code{markPAI} can categorize physical activity intensity level based
on user-defined cut-points of accelerometer counts.
@end enumerate
  It also supports importing ActiGraph (AGD) files with @code{readActigraph} and
@code{queryActigraph} functions.")
    (license license:gpl3+)))

(define-public r-acc
  (package
    (name "r-acc")
    (version "1.3.3")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "acc" version))
       (sha256
        (base32 "1ii2vm47djxbixa75h690q1s2f9m9x6i8nkygik93j6dayr6kr1m"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-circlize" ,r-circlize)
       ("r-dbi" ,r-dbi)
       ("r-ggplot2" ,r-ggplot2)
       ("r-iterators" ,r-iterators)
       ("r-mhsmm" ,r-mhsmm)
       ("r-nleqslv" ,r-nleqslv)
       ("r-physicalactivity" ,r-physicalactivity)
       ("r-plyr" ,r-plyr)
       ("r-r-utils" ,r-r-utils)
       ("r-rcpp" ,r-rcpp)
       ("r-rcpparmadillo" ,r-rcpparmadillo)
       ("r-rsqlite" ,r-rsqlite)
       ("r-zoo" ,r-zoo)))
    (home-page "https://cran.r-project.org/web/packages/acc/")
    (synopsis "Exploring accelerometer data")
    (description
     "This package processes accelerometer data from uni-axial and tri-axial devices
and generates data summaries.  Also, includes functions to plot, analyze, and
simulate accelerometer data.")
    (license license:gpl2+)))

(define-public r-rbenchmark
  (package
    (name "r-rbenchmark")
    (version "1.0.0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "rbenchmark" version))
       (sha256
        (base32 "010fn3qwnk2k411cbqyvra1d12c3bhhl3spzm8kxffmirj4p2al9"))))
    (build-system r-build-system)
    (home-page "https://cran.r-project.org/web/packages/rbenchmark/")
    (synopsis "Benchmarking routine for R")
    (description
     "This @code{r-rbenchmark} package is inspired by the Perl module Benchmark,
and is intended to facilitate benchmarking of arbitrary R code.  The library
consists of just one function, benchmark, which is a simple wrapper around
system.time.  Given a specification of the benchmarking process (counts of
replications, evaluation environment) and an arbitrary number of expressions,
benchmark evaluates each of the expressions in the specified environment,
replicating the evaluation as many times as specified, and returning the results
conveniently wrapped into a data frame.")
    (license license:gpl2+)))

(define-public r-mitools
  (package
    (name "r-mitools")
    (version "2.4")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "mitools" version))
       (sha256
        (base32
         "0c2x2n1p53lcw0vx4vmy5j7m2f95i7g2iwbryl89imr99rvz617j"))))
    (build-system r-build-system)
    (propagated-inputs `(("r-dbi" ,r-dbi)))
    (home-page "https://cran.r-project.org/web/packages/mitools/")
    (synopsis "Tools for multiple imputation of missing data")
    (description
     "This package provides tools to perform analyses and combine results from
multiple-imputation datasets.")
    (license license:gpl2)))

(define-public r-magick
  (package
    (name "r-magick")
    (version "2.3")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "magick" version))
       (sha256
        (base32
         "182b4wahkq9q0scn99mql4vm9fp92nja0r5yizc4x9rjl492ahd8"))))
    (build-system r-build-system)
    (inputs
     `(("imagemagick" ,imagemagick)
       ("zlib" ,zlib)))
    (propagated-inputs
     `(("r-curl" ,r-curl)
       ("r-magrittr" ,r-magrittr)
       ("r-rcpp" ,r-rcpp)))
    (native-inputs
     `(("pkg-config" ,pkg-config)))
    (home-page "https://github.com/ropensci/magick")
    (synopsis "Advanced graphics and image-processing in R")
    (description
     "This package provides bindings to ImageMagick, a comprehensive image
processing library.  It supports many common formats (PNG, JPEG, TIFF, PDF,
etc.)  and manipulations (rotate, scale, crop, trim, flip, blur, etc).  All
operations are vectorized via the Magick++ STL meaning they operate either on
a single frame or a series of frames for working with layers, collages, or
animation.  In RStudio, images are automatically previewed when printed to the
console, resulting in an interactive editing environment.")
    (license license:expat)))

(define-public r-survey
  (package
    (name "r-survey")
    (version "3.37")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "survey" version))
       (sha256
        (base32
         "1f31dvh48gzzan13pdrwh84ls35x9116095i7mdrcbrhz809r8dy"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-lattice" ,r-lattice)
       ("r-matrix" ,r-matrix)
       ("r-minqa" ,r-minqa)
       ("r-mitools" ,r-mitools)
       ("r-numderiv" ,r-numderiv)
       ("r-survival" ,r-survival)))
    (home-page "http://r-survey.r-forge.r-project.org/survey/")
    (synopsis "Analysis of complex survey samples")
    (description
     "This package provides tools for the analysis of complex survey samples.
The provided features include: summary statistics, two-sample tests, rank
tests, generalised linear models, cumulative link models, Cox models,
loglinear models, and general maximum pseudolikelihood estimation for
multistage stratified, cluster-sampled, unequally weighted survey samples;
variances by Taylor series linearisation or replicate weights;
post-stratification, calibration, and raking; two-phase subsampling designs;
graphics; PPS sampling without replacement; principal components, and factor
analysis.")
    ;; Either version of the GPL.
    (license (list license:gpl2 license:gpl3))))

(define-public r-gee
  (package
    (name "r-gee")
    (version "4.13-20")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "gee" version))
       (sha256
        (base32
         "167pzgnmj4cjc41ykps1mfwi6s7y32zxyycn5z17vn4v0pp4q0ak"))))
    (properties `((upstream-name . "gee")))
    (build-system r-build-system)
    (native-inputs
     `(("gfortran" ,gfortran)))
    (home-page "https://cran.r-project.org/web/packages/gee/")
    (synopsis "Generalized estimation equation solver")
    (description
     "This package provides a solver for generalized estimation equations.")
    (license license:gpl2)))

(define-public r-tab
  (package
    (name "r-tab")
    (version "4.1.1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "tab" version))
       (sha256
        (base32
         "0ds8n6gncidb66in7hlqkcmil5yfsf7ihqvmls789hrm2iz9xlfm"))))
    (properties `((upstream-name . "tab")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-dplyr" ,r-dplyr)
       ("r-gee" ,r-gee)
       ("r-knitr" ,r-knitr)
       ("r-mass" ,r-mass)
       ("r-survey" ,r-survey)
       ("r-survival" ,r-survival)
       ("r-xtable" ,r-xtable)))
    (home-page "https://cran.r-project.org/web/packages/tab/")
    (synopsis "Create summary tables for statistical reports")
    (description
     "This package contains functions for creating various types of summary
tables, e.g. comparing characteristics across levels of a categorical variable
and summarizing fitted generalized linear models, generalized estimating
equations, and Cox proportional hazards models.  Functions are available to
handle data from simple random samples as well as complex surveys.")
    (license license:gpl3+)))

(define-public r-dvmisc
  (package
    (name "r-dvmisc")
    (version "1.1.4")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "dvmisc" version))
       (sha256
        (base32 "01v6sixx0f3nrn6ymfifb3pvd2msfrwm21kmdv38laxq29vc4rsi"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-cubature" ,r-cubature)
       ("r-data-table" ,r-data-table)
       ("r-dplyr" ,r-dplyr)
       ("r-ggplot2" ,r-ggplot2)
       ("r-mass" ,r-mass)
       ("r-mvtnorm" ,r-mvtnorm)
       ("r-pracma" ,r-pracma)
       ("r-rbenchmark" ,r-rbenchmark)
       ("r-rcpp" ,r-rcpp)
       ("r-survey" ,r-survey)
       ("r-tab" ,r-tab)))
    (home-page "https://cran.r-project.org/web/packages/dvmisc/")
    (synopsis "Faster computation of common statistics and miscellaneous functions")
    (description
     "This package implements faster versions of base R functions (e.g. mean, standard
deviation, covariance, weighted mean), mostly written in C++, along with
miscellaneous functions for various purposes (e.g. create the histogram with
fitted probability density function or probability mass function curve, create
the body mass index groups, assess the linearity assumption in logistic
regression).")
    (license license:gpl2)))

(define-public r-accelerometry
  (package
    (name "r-accelerometry")
    (version "3.1.2")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "accelerometry" version))
       (sha256
        (base32 "13xzrwhr4i1nj9c8vrmfdg2rmrc8n446iihcyxmy99sm99hpzyip"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-dvmisc" ,r-dvmisc)
       ("r-rcpp" ,r-rcpp)))
    (home-page "https://cran.r-project.org/web/packages/accelerometry/")
    (synopsis "Functions for processing accelerometer data")
    (description
     "This package provides a collection of functions that perform operations on
time-series accelerometer data, such as identify the non-wear time, flag minutes
that are part of an activity bout, and find the maximum 10-minute average count
value.  The functions are generally very flexible, allowing for a variety of
algorithms to be implemented.")
    (license license:gpl3)))

(define-public r-absim
  (package
    (name "r-absim")
    (version "0.2.6")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "AbSim" version))
       (sha256
        (base32 "16ddjk8b6xw80ch4jis1y751i9561wdxh0gifbf15qiz3vjckq8m"))))
    (properties `((upstream-name . "AbSim")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-ape" ,r-ape)
       ("r-powerlaw" ,r-powerlaw)))
    (home-page "https://cran.r-project.org/web/packages/AbSim/")
    (synopsis "Time resolved simulations of antibody repertoires")
    (description
     "This package provides simulation methods for the evolution of antibody repertoires.
  The heavy and light chain variable region of both human and C57BL/6 mice can
be simulated in a time-dependent fashion.  Both single lineages using one set of
V-, D-, and J-genes or full repertoires can be simulated.  The algorithm begins
with an initial V-D-J recombination event, starting the first phylogenetic tree.
  Upon completion, the main loop of the algorithm begins, with each iteration
representing one simulated time step.  Various mutation events are possible at
each time step, contributing to a diverse final repertoire.")
    (license license:gpl2)))

(define-public r-quic
  (package
    (name "r-quic")
    (version "1.1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "QUIC" version))
       (sha256
        (base32 "021bp9xbaih60qmss015ycblbv6d1dvb1z89y93zpqqnc2qhpv3c"))))
    (properties `((upstream-name . "QUIC")))
    (build-system r-build-system)
    (home-page "https://www.cs.utexas.edu/users/sustik/QUIC/")
    (synopsis "Regularized sparse inverse covariance matrix estimation")
    (description
     "This package implements the regularized Gaussian maximum likelihood
estimation of the inverse of a covariance matrix.  It uses Newton's method and
coordinate descent to solve the regularized inverse covariance matrix
estimation problem.")
    ;; The project home page states that the release is under GPLv3 or later.
    ;; The CRAN page only says GPL-3.
    (license license:gpl3+)))

(define-public r-abundant
  (package
    (name "r-abundant")
    (version "1.1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "abundant" version))
       (sha256
        (base32 "1m76qdmqvwpgm0sihazi2dna7cgsz9rljal18vgffb5wamwmg9k7"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-quic" ,r-quic)))
    (home-page "https://cran.r-project.org/web/packages/abundant/")
    (synopsis "Abundant regression and high-dimensional principal fitted components")
    (description
     "This package provides tools to fit and predict with the high-dimensional
principal fitted components model.  This model is described by Cook, Forzani,
and Rothman (2012) @url{doi:10.1214/11-AOS962}.")
    ;; The DESCRIPTION file states GPL-2, but since it directly depends on a
    ;; GPLv3+ package (QUIC) this likely means GPLv2+.
    (license license:gpl2+)))

(define-public r-ac3net
  (package
    (name "r-ac3net")
    (version "1.2.2")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "Ac3net" version))
       (sha256
        (base32 "1ns4n0xxz6p34c11bj0k7nzgmyqr9mis2b0g5nfz37dbikndyqyz"))))
    (properties `((upstream-name . "Ac3net")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-data-table" ,r-data-table)))
    (home-page "https://cran.r-project.org/web/packages/Ac3net/")
    (synopsis "Inferring directional conservative causal core gene networks")
    (description "This package infers directional Conservative causal core
(gene) networks (C3NET).  This is a version of the algorithm C3NET with
directional network.")
    (license license:gpl3+)))

(define-public r-aca
  (package
    (name "r-aca")
    (version "1.1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "ACA" version))
       (sha256
        (base32 "1i3hm27nvnkvc39xlh0d1blq8q0q02czmvgi3cazmjx3jvxay0vq"))))
    (properties `((upstream-name . "ACA")))
    (build-system r-build-system)
    (home-page "https://cran.r-project.org/web/packages/ACA/")
    (synopsis "Abrupt change-point or aberration detection in point series")
    (description
     "This package offers an interactive function for the detection of breakpoints in
series.")
    ;; Any version of the GPL
    (license (list license:gpl2+ license:gpl3+))))

(define-public r-acceptancesampling
  (package
    (name "r-acceptancesampling")
    (version "1.0-6")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "AcceptanceSampling" version))
       (sha256
        (base32 "1z3rmln63ki2kik9kinbwr9qhr32ggbmh4mm3xqy6di119n47ca9"))))
    (properties
     `((upstream-name . "AcceptanceSampling")))
    (build-system r-build-system)
    (home-page "https://cran.r-project.org/web/packages/AcceptanceSampling/")
    (synopsis "Creation and evaluation of acceptance sampling plans")
    (description
     "This @code{r-acceptancesampling} provides functionality for creating and evaluating
acceptance sampling plans.  Acceptance sampling is a methodology commonly used
in quality control and improvement.  International standards of acceptance
sampling provide sampling plans for specific circumstances.  The aim of this
package is to provide an easy-to-use interface to visualize single, double or
multiple sampling plans.  In addition, methods have been provided to enable the
user to assess sampling plans against pre-specified levels of performance, as
measured by the probability of acceptance for a given level of quality in the
lot.")
    (license license:gpl3+)))

(define-public r-acclma
  (package
    (name "r-acclma")
    (version "1.0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "ACCLMA" version))
       (sha256
        (base32 "1na27sp18fq12gp6vxgqw1ffsz2yi1d8xvrxbrzx5g1kqxrayy0v"))))
    (properties `((upstream-name . "ACCLMA")))
    (build-system r-build-system)
    (home-page "https://cran.r-project.org/web/packages/ACCLMA/")
    (synopsis "ACC & LMA graph plotting")
    (description
     "This package contains a function that imports data from a @acronym{CSV,
Comma-Separated Values} file, or uses manually entered data from the format (x,
y, weight) and plots the appropriate @acronym{ACC, Absolute Concentration
Curve} vs @acronym{LOI, Line of Independence} graph and
@acronym{LMA, @acronym{LOI} Minus @acronym{ACC}} graph.  The main
function is @code{plotLMA} (source file, header) that takes a data set and plots the
appropriate @acronym{LMA} and @acronym{ACC} graphs.  If no source file (a
string) was passed, a manual data entry window is opened.  The header parameter
indicates by TRUE/FALSE (false by default) if the source @acronym{CSV} file has
a header row or not.  The dataset should contain only one independent variable
(x) and one dependent variable (y) and can contain a weight for each
observation.")
    (license license:gpl2)))

(define-public r-aspi
  (package
    (name "r-aspi")
    (version "0.2.0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "aspi" version))
       (sha256
        (base32 "0rhvxw243vvdv3hxa6pi343gcjc2cbxq1jzqirl9k1l4i3897l87"))))
    (build-system r-build-system)
    (home-page
     "https://cran.r-project.org/web/packages/aspi/")
    (synopsis
     "Analysis of symmetry of parasitic infections")
    (description
     "This package provides tools for the analysis and visualization of bilateral
      asymmetry in parasitic infections.")
    (license license:gpl3+)))

(define-public r-sandwich
  (package
    (name "r-sandwich")
    (version "2.5-1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "sandwich" version))
       (sha256
        (base32
         "1mk685b9wq7k566pbml52rj96i5h6b3vf215k9picgmq296nzvyv"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-zoo" ,r-zoo)))
    (home-page "https://cran.r-project.org/web/packages/sandwich/")
    (synopsis "Robust Covariance Matrix Estimators")
    (description
     "This package provides model-robust standard error estimators for
cross-sectional, time series, clustered, panel, and longitudinal data.")
    ;; Either version of the license.
    (license (list license:gpl2 license:gpl3))))

(define-public r-th-data
  (package
    (name "r-th-data")
    (version "1.0-10")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "TH.data" version))
       (sha256
        (base32
         "0mgz7aj2d9abbmdr65zgmg1ddp3fdbs3mfj83r5xadh5ldkir2k1"))))
    (properties `((upstream-name . "TH.data")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-mass" ,r-mass)
       ("r-survival" ,r-survival)))
    (home-page "https://cran.r-project.org/web/packages/TH.data/")
    (synopsis "Shared data sets")
    (description
     "This package contains supporting data sets that are used in other
packages maintained by Torsten Hothorn.")
    (license license:gpl3)))

(define-public r-multcomp
  (package
    (name "r-multcomp")
    (version "1.4-12")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "multcomp" version))
       (sha256
        (base32
         "14c2f10rz546w7ly5f4r6wnd07yj5gic38an17gxny1vf2nsff0b"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-codetools" ,r-codetools)
       ("r-mvtnorm" ,r-mvtnorm)
       ("r-sandwich" ,r-sandwich)
       ("r-survival" ,r-survival)
       ("r-th-data" ,r-th-data)))
    (home-page "https://cran.r-project.org/web/packages/multcomp/")
    (synopsis "Simultaneous inference in general parametric models")
    (description
     "Simultaneous tests and confidence intervals for general linear
hypotheses in parametric models, including linear, generalized linear, linear
mixed effects, and survival models.  The package includes demos reproducing
analyzes presented in the book \"Multiple Comparisons Using R\" (Bretz,
Hothorn, Westfall, 2010, CRC Press).")
    (license license:gpl2)))

(define-public r-emmeans
  (package
    (name "r-emmeans")
    (version "1.4.5")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "emmeans" version))
       (sha256
        (base32
         "10fmvmd6q4zjr6b18hhc85mwrzv778qzj6lwl9kbs2fsfvsgw7mm"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-estimability" ,r-estimability)
       ("r-mvtnorm" ,r-mvtnorm)
       ("r-numderiv" ,r-numderiv)
       ("r-plyr" ,r-plyr)
       ("r-xtable" ,r-xtable)))
    (home-page "https://github.com/rvlenth/emmeans")
    (synopsis "Estimated marginal means, aka least-squares means")
    (description
     "This package provides tools to obtain @dfn{estimated marginal
means} (EMMs) for many linear, generalized linear, and mixed models.  It can
be used to compute contrasts or linear functions of EMMs, trends, and
comparisons of slopes.")
    ;; Either version of the license.
    (license (list license:gpl2 license:gpl3))))

(define-public r-pwr
  (package
    (name "r-pwr")
    (version "1.3-0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "pwr" version))
       (sha256
        (base32
         "1kfzy73v3z6ipc3kdfkcjrp4b4p5k54nwk796gqi36srm93hgc2v"))))
    (build-system r-build-system)
    (native-inputs
     `(("r-knitr" ,r-knitr)))
    (home-page "https://github.com/heliosdrm/pwr")
    (synopsis "Basic functions for power analysis")
    (description
     "This package provides power analysis functions along the lines of
Cohen (1988).")
    (license license:gpl3+)))

(define-public r-libcoin
  (package
    (name "r-libcoin")
    (version "1.0-5")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "libcoin" version))
       (sha256
        (base32
         "1cm9x1dlg9f7fh7n5nw3x4a7rl88c7ylrlc8x3rx4mq5w1j42x0a"))))
    (build-system r-build-system)
    (propagated-inputs `(("r-mvtnorm" ,r-mvtnorm)))
    (home-page "https://cran.r-project.org/web/packages/libcoin")
    (synopsis "Linear test statistics for permutation inference")
    (description
     "This package provides basic infrastructure for linear test statistics
and permutation inference in the framework of Strasser and Weber (1999).")
    (license license:gpl2)))

(define-public r-coin
  (package
    (name "r-coin")
    (version "1.3-1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "coin" version))
       (sha256
        (base32
         "0qi03fyqw42a2vnqcia5l2m1mzyarj2q1iblknx9n19bdsd53qjx"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-libcoin" ,r-libcoin)
       ("r-matrixstats" ,r-matrixstats)
       ("r-modeltools" ,r-modeltools)
       ("r-multcomp" ,r-multcomp)
       ("r-mvtnorm" ,r-mvtnorm)
       ("r-survival" ,r-survival)))
    (home-page "http://coin.r-forge.r-project.org")
    (synopsis "Conditional inference procedures in a permutation test framework")
    (description
     "This package provides conditional inference procedures for the general
independence problem including two-sample, K-sample (non-parametric ANOVA),
correlation, censored, ordered and multivariate problems.")
    (license license:gpl2)))

(define-public r-bayesplot
  (package
    (name "r-bayesplot")
    (version "1.7.1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "bayesplot" version))
       (sha256
        (base32
         "0sq0ajnm96hmlqf1cv5n2gshh3qdij4n1zbm7qrniz2q6b5aj342"))))
    (build-system r-build-system)
    (inputs
     `(("pandoc" ,ghc-pandoc)
       ("pandoc-citeproc" ,ghc-pandoc-citeproc)))
    (propagated-inputs
     `(("r-dplyr" ,r-dplyr)
       ("r-ggplot2" ,r-ggplot2)
       ("r-ggridges" ,r-ggridges)
       ("r-glue" ,r-glue)
       ("r-reshape2" ,r-reshape2)
       ("r-rlang" ,r-rlang)
       ("r-tibble" ,r-tibble)
       ("r-tidyselect" ,r-tidyselect)))
    (home-page "https://mc-stan.org/bayesplot")
    (synopsis "Plotting for Bayesian models")
    (description
     "This package provides plotting functions for posterior analysis, model
checking, and MCMC diagnostics.  The package is designed not only to provide
convenient functionality for users, but also a common set of functions that
can be easily used by developers working on a variety of R packages for
Bayesian modeling.")
    (license license:gpl3+)))

(define-public r-tmb
  (package
    (name "r-tmb")
    (version "1.7.16")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "TMB" version))
       (sha256
        (base32
         "0lly12hdi99iklwr0vg9xkyhi038w4gncbf895qcwbndmqp0lx44"))))
    (properties `((upstream-name . "TMB")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-matrix" ,r-matrix)
       ("r-rcppeigen" ,r-rcppeigen)))
    (home-page "http://tmb-project.org")
    (synopsis "Template model builder: a general random effect tool")
    (description
     "With this tool, a user should be able to quickly implement complex
random effect models through simple C++ templates.  The package combines
@code{CppAD} (C++ automatic differentiation), @code{Eigen} (templated
matrix-vector library) and @code{CHOLMOD} (sparse matrix routines available
from R) to obtain an efficient implementation of the applied Laplace
approximation with exact derivatives.  Key features are: Automatic sparseness
detection, parallelism through BLAS and parallel user templates.")
    (license license:gpl2)))

(define-public r-sjstats
  (package
    (name "r-sjstats")
    (version "0.17.9")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "sjstats" version))
       (sha256
        (base32 "0938ac6ixvkif07azd2msa8g3qnn9rabj6jg17almbysl83kg4nm"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-bayestestr" ,r-bayestestr)
       ("r-broom" ,r-broom)
       ("r-dplyr" ,r-dplyr)
       ("r-effectsize" ,r-effectsize)
       ("r-emmeans" ,r-emmeans)
       ("r-insight" ,r-insight)
       ("r-lme4" ,r-lme4)
       ("r-magrittr" ,r-magrittr)
       ("r-mass" ,r-mass)
       ("r-modelr" ,r-modelr)
       ("r-parameters" ,r-parameters)
       ("r-performance" ,r-performance)
       ("r-purrr" ,r-purrr)
       ("r-rlang" ,r-rlang)
       ("r-sjlabelled" ,r-sjlabelled)
       ("r-sjmisc" ,r-sjmisc)
       ("r-tidyr" ,r-tidyr)))
    (home-page "https://github.com/strengejacke/sjstats")
    (synopsis "Functions for common statistical computations")
    (description
     "This package provides a collection of convenient functions for common
statistical computations, which are not directly provided by R's @code{base}
or @code{stats} packages.  This package aims at providing, first, shortcuts
for statistical measures, which otherwise could only be calculated with
additional effort.  Second, these shortcut functions are generic, and can be
applied not only to vectors, but also to other objects as well.  The focus of
most functions lies on summary statistics or fit measures for regression
models, including generalized linear models, mixed effects models and Bayesian
models.")
    (license license:gpl3)))

(define-public r-glmmtmb
  (package
    (name "r-glmmtmb")
    (version "1.0.1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "glmmTMB" version))
       (sha256
        (base32
         "0sdx1q7wc7895xh8747r4p0wkij0xjgn5ij62ipi9423zd0sr0mm"))))
    (properties `((upstream-name . "glmmTMB")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-lme4" ,r-lme4)
       ("r-matrix" ,r-matrix)
       ("r-nlme" ,r-nlme)
       ("r-rcppeigen" ,r-rcppeigen)
       ("r-tmb" ,r-tmb)))
    (native-inputs
     `(("r-knitr" ,r-knitr))) ; for vignettes
    (home-page "https://github.com/glmmTMB")
    (synopsis "Generalized linear mixed models")
    (description
     "Fit linear and generalized linear mixed models with various extensions,
including zero-inflation.  The models are fitted using maximum likelihood
estimation via the Template Model Builder.  Random effects are assumed to be
Gaussian on the scale of the linear predictor and are integrated out using the
Laplace approximation.  Gradients are calculated using automatic
differentiation.")
    (license license:agpl3+)))

(define-public r-bayestestr
  (package
    (name "r-bayestestr")
    (version "0.5.3")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "bayestestR" version))
       (sha256
        (base32
         "1q24qh5p6bz4nbf4546kckh7d518x5pm1yhhbc8fwcnbca4kgqjz"))))
    (properties `((upstream-name . "bayestestR")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-insight" ,r-insight)))
    (native-inputs
     `(("r-knitr" ,r-knitr)))
    (home-page "https://github.com/easystats/bayestestR")
    (synopsis "Describe Bayesian models and posterior distributions")
    (description
     "This package provides utilities to understand and describe posterior
distributions and Bayesian models.  It includes point-estimates such as
@dfn{Maximum A Posteriori} (MAP), measures of dispersion such as @dfn{Highest
Density Interval} (HDI), and indices used for null-hypothesis testing (such as
ROPE percentage and pd).")
    (license license:gpl3)))

(define-public r-performance
  (package
    (name "r-performance")
    (version "0.4.5")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "performance" version))
       (sha256
        (base32
         "0j6wmnwhfdd3v1a17qmg491q50579knjzscmyr4yk3xr0jbsbg8x"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-bayestestr" ,r-bayestestr)
       ("r-insight" ,r-insight)))
    (home-page "https://easystats.github.io/performance/")
    (synopsis "Assessment of regression models performance")
    (description
     "This package provides utilities for computing measures to assess model
quality, which are not directly provided by R's @code{base} or @code{stats}
packages.  These include e.g. measures like r-squared, intraclass correlation
coefficient, root mean squared error or functions to check models for
overdispersion, singularity or zero-inflation and more.  Functions apply to a
large variety of regression models, including generalized linear models, mixed
effects models and Bayesian models.")
    (license license:gpl3)))

(define-public r-ggeffects
  (package
    (name "r-ggeffects")
    (version "0.14.2")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "ggeffects" version))
       (sha256
        (base32
         "1y3yfb07jrr6vkc8hk6rp52l70dj7042jvqgjzllslzy7hx2jhyw"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-insight" ,r-insight)
       ("r-mass" ,r-mass)
       ("r-sjlabelled" ,r-sjlabelled)))
    (native-inputs
     `(("r-knitr" ,r-knitr)))
    (home-page "https://github.com/strengejacke/ggeffects")
    (synopsis "Create tidy data frames of marginal effects for ggplot")
    (description
     "This package provides tools to compute marginal effects from statistical
models and return the result as tidy data frames.  These data frames are ready
to use with the @code{ggplot2} package.  Marginal effects can be calculated
for many different models.  Interaction terms, splines and polynomial terms
are also supported.  The two main functions are @code{ggpredict()} and
@code{ggeffect()}.  There is a generic @code{plot()} method to plot the
results using @code{ggplot2}.")
    (license license:gpl3)))

(define-public r-effectsize
  (package
    (name "r-effectsize")
    (version "0.2.0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "effectsize" version))
       (sha256
        (base32
         "1liix8rf8xq3hzi7684bl0s20iflsq6g5mxr5k59wp2qwn1i6aww"))))
    (properties `((upstream-name . "effectsize")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-bayestestr" ,r-bayestestr)
       ("r-insight" ,r-insight)
       ("r-parameters" ,r-parameters)))
    (home-page "https://github.com/easystats/effectsize")
    (synopsis "Indices of effect size and standardized parameters")
    (description
     "This package provides utilities to work with indices of effect size and
standardized parameters for a wide variety of models, allowing computation and
conversion of indices such as Cohen's d, r, odds, etc.")
    (license license:gpl3)))

(define-public r-sjplot
  (package
    (name "r-sjplot")
    (version "2.8.3")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "sjPlot" version))
       (sha256
        (base32 "0ip1rkjlhyf3axlc8qqss1qq1f0xrda890c1jmcbhm98wwjw264f"))))
    (properties `((upstream-name . "sjPlot")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-bayestestr" ,r-bayestestr)
       ("r-dplyr" ,r-dplyr)
       ("r-effectsize" ,r-effectsize)
       ("r-ggeffects" ,r-ggeffects)
       ("r-ggplot2" ,r-ggplot2)
       ("r-insight" ,r-insight)
       ("r-knitr" ,r-knitr)
       ("r-mass" ,r-mass)
       ("r-parameters" ,r-parameters)
       ("r-performance" ,r-performance)
       ("r-purrr" ,r-purrr)
       ("r-rlang" ,r-rlang)
       ("r-scales" ,r-scales)
       ("r-sjlabelled" ,r-sjlabelled)
       ("r-sjmisc" ,r-sjmisc)
       ("r-sjstats" ,r-sjstats)
       ("r-tidyr" ,r-tidyr)))
    (native-inputs
     `(("r-knitr" ,r-knitr)))
    (home-page "https://strengejacke.github.io/sjPlot/")
    (synopsis "Data visualization for statistics in social science")
    (description
     "This package represents a collection of plotting and table output
functions for data visualization.  Results of various statistical
analyses (that are commonly used in social sciences) can be visualized using
this package, including simple and cross tabulated frequencies, histograms,
box plots, (generalized) linear models, mixed effects models, principal
component analysis and correlation matrices, cluster analyses, scatter plots,
stacked scales, effects plots of regression models (including interaction
terms) and much more.  This package supports labelled data.")
    (license license:gpl3)))

(define-public r-ini
  (package
    (name "r-ini")
    (version "0.3.1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "ini" version))
       (sha256
        (base32
         "04yqij344dwm0xqgara8xia42mlmij3i8711qbb5534w05a1l6bv"))))
    (build-system r-build-system)
    (home-page "https://github.com/dvdscripter/ini")
    (synopsis "Read and write configuration files")
    (description
     "This package provides tools to parse simple @code{.ini} configuration
files to an structured list.  Users can manipulate this resulting list with
@code{lapply()} functions.  This same structured list can be used to write
back to file after modifications.")
    (license license:gpl3)))

(define-public r-gh
  (package
    (name "r-gh")
    (version "1.1.0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "gh" version))
       (sha256
        (base32
         "1bc9bn1078s664hc806dh0y1ncxif77q479rfmxfir9z7hwaz7yy"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-cli" ,r-cli)
       ("r-httr" ,r-httr)
       ("r-ini" ,r-ini)
       ("r-jsonlite" ,r-jsonlite)))
    (home-page "https://github.com/r-lib/gh#readme")
    (synopsis "Access the GitHub API via R")
    (description
     "This package provides a minimal R client to access the GitHub API.")
    (license license:expat)))

(define-public r-fs
  (package
    (name "r-fs")
    (version "1.4.0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "fs" version))
       (sha256
        (base32
         "1ishdxrxy88w1lrn657a573wdra5v7xf1yfa1c4kss07rlynwrj7"))))
    (build-system r-build-system)
    (native-inputs
     `(("pkg-config" ,pkg-config)
       ("r-knitr" ,r-knitr)))
    (home-page "https://fs.r-lib.org")
    (synopsis "Cross-platform file system operations based on libuv")
    (description
     "This package provides a cross-platform interface to file system
operations, built on top of the libuv C library.")
    (license license:gpl3)))

(define-public r-clisymbols
  (package
    (name "r-clisymbols")
    (version "1.2.0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "clisymbols" version))
       (sha256
        (base32
         "1q7gi2zmykhzas9v8fdnbpdq7pzdcpbhim1yxvd2062l777g4j86"))))
    (build-system r-build-system)
    (home-page "https://github.com/gaborcsardi/clisymbols")
    (synopsis "Unicode symbols at the R prompt")
    (description
     "This package provides a small subset of Unicode symbols, that are useful
when building command line applications.  They fall back to alternatives on
terminals that do not support Unicode.")
    (license license:expat)))

(define-public r-usethis
  (package
    (name "r-usethis")
    (version "1.5.1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "usethis" version))
       (sha256
        (base32
         "07an5wbikilg7cb3q6x5aykw8dfqnjrc3wpfb7gjmy0d9fh20fcy"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-clipr" ,r-clipr)
       ("r-clisymbols" ,r-clisymbols)
       ("r-crayon" ,r-crayon)
       ("r-curl" ,r-curl)
       ("r-desc" ,r-desc)
       ("r-fs" ,r-fs)
       ("r-gh" ,r-gh)
       ("r-git2r" ,r-git2r)
       ("r-glue" ,r-glue)
       ("r-purrr" ,r-purrr)
       ("r-rlang" ,r-rlang)
       ("r-rprojroot" ,r-rprojroot)
       ("r-rstudioapi" ,r-rstudioapi)
       ("r-whisker" ,r-whisker)
       ("r-withr" ,r-withr)
       ("r-yaml" ,r-yaml)))
    (home-page "https://github.com/r-lib/usethis")
    (synopsis "Automate R package and project setup")
    (description
     "This package helps you to automate R package and project setup tasks
that are otherwise performed manually.  This includes setting up unit testing,
test coverage, continuous integration, Git, GitHub integration, licenses,
Rcpp, RStudio projects, and more.")
    (license license:gpl3)))

(define-public r-sessioninfo
  (package
    (name "r-sessioninfo")
    (version "1.1.1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "sessioninfo" version))
       (sha256
        (base32
         "0j5f3l58fynxx3v0w62vqpii7miabszgljpja36xx9s8hikh8sqn"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-cli" ,r-cli)
       ("r-withr" ,r-withr)))
    (home-page "https://github.com/r-lib/sessioninfo#readme")
    (synopsis "R session information")
    (description
     "This package provides tools to query and print information about the
current R session.  It is similar to @code{utils::sessionInfo()}, but includes
more information about packages, and where they were installed from.")
    (license license:gpl2)))

(define-public r-remotes
  (package
    (name "r-remotes")
    (version "2.1.1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "remotes" version))
       (sha256
        (base32
         "12qinl7jv54f2524ri13gcrv6d523rg1harpi500j676zi30fnaf"))))
    (build-system r-build-system)
    (home-page "https://github.com/r-lib/remotes#readme")
    (synopsis "R package installation from remote repositories")
    (description
     "Download and install R packages stored in GitHub, BitBucket, or plain
subversion or git repositories.  This package is a lightweight replacement of
the @code{install_*} functions in the @code{devtools} package.  Indeed most of
the code was copied over from @code{devtools}.")
    (license license:gpl2+)))

(define-public r-xopen
  (package
    (name "r-xopen")
    (version "1.0.0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "xopen" version))
       (sha256
        (base32
         "1vrvgdika1d63dwygynbv2wmd87ll8dji5dy89hj576n8hw601z2"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-processx" ,r-processx)))
    (home-page "https://github.com/r-lib/xopen#readme")
    (synopsis "Open system files, URLs, anything")
    (description
     "This package provides a cross-platform solution to open files,
directories or URLs with their associated programs.")
    (license license:expat)))

(define-public r-rcmdcheck
  (package
    (name "r-rcmdcheck")
    (version "1.3.3")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "rcmdcheck" version))
       (sha256
        (base32
         "1d4kzgfqy72r6b7bn1j4znyksrycgypx1jjvpv9lrmvn37mpkdhs"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-callr" ,r-callr)
       ("r-cli" ,r-cli)
       ("r-crayon" ,r-crayon)
       ("r-desc" ,r-desc)
       ("r-digest" ,r-digest)
       ("r-pkgbuild" ,r-pkgbuild)
       ("r-prettyunits" ,r-prettyunits)
       ("r-r6" ,r-r6)
       ("r-rprojroot" ,r-rprojroot)
       ("r-sessioninfo" ,r-sessioninfo)
       ("r-withr" ,r-withr)
       ("r-xopen" ,r-xopen)))
    (home-page "https://github.com/r-Lib/rcmdcheck#readme")
    (synopsis "Run R CMD check from R and capture results")
    (description
     "Run @code{R CMD check} from R programmatically, and capture the results
of the individual checks.")
    (license license:expat)))

(define-public r-rapportools
  (package
    (name "r-rapportools")
    (version "1.0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "rapportools" version))
       (sha256
        (base32
         "1sgv4sc737i12arh5dc3263kjsz3dzg06qihfmrqyax94mv2d01b"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-pander" ,r-pander)
       ("r-plyr" ,r-plyr)
       ("r-reshape" ,r-reshape)))
    (home-page "https://cran.r-project.org/web/packages/rapportools/")
    (synopsis "Miscellaneous helper functions with sane defaults for reporting")
    (description
     "This package provides helper functions that act as wrappers to more
advanced statistical methods with the advantage of having sane defaults for
quick reporting.")
    (license license:agpl3+)))

(define-public r-pander
  (package
    (name "r-pander")
    (version "0.6.3")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "pander" version))
       (sha256
        (base32
         "1bd9sdghlsppmff18k5fg3i0visq9f4wc82rlhwq5m82bmgdgnyi"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-digest" ,r-digest)
       ("r-rcpp" ,r-rcpp)))
    (home-page "https://rapporter.github.io/pander")
    (synopsis "Render R objects into Pandoc's markdown")
    (description
     "The main aim of the pander R package is to provide a minimal and easy
tool for rendering R objects into Pandoc's markdown.  The package is also
capable of exporting/converting complex Pandoc documents (reports) in various
ways.")
    ;; This package is licensed under either the AGPLv3+ or the very rarely
    ;; used OSL 3.0.
    (license license:agpl3+)))

(define-public r-summarytools
  (package
    (name "r-summarytools")
    (version "0.9.6")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "summarytools" version))
       (sha256
        (base32
         "03pcb2ild1rb9f15yq8b68p9bg10z5wk2x7ahgyzkwdh5f81vbq2"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-base64enc" ,r-base64enc)
       ("r-checkmate" ,r-checkmate)
       ("r-dplyr" ,r-dplyr)
       ("r-htmltools" ,r-htmltools)
       ("r-lubridate" ,r-lubridate)
       ("r-magick" ,r-magick)
       ("r-matrixstats" ,r-matrixstats)
       ("r-pander" ,r-pander)
       ("r-pryr" ,r-pryr)
       ("r-rapportools" ,r-rapportools)
       ("r-tibble" ,r-tibble)
       ("r-tidyr" ,r-tidyr)))
    (home-page "https://github.com/dcomtois/summarytools")
    (synopsis "Tools to quickly and neatly summarize data")
    (description
     "This package provides tools for data frame summaries, cross-tabulations,
weight-enabled frequency tables and common univariate statistics in concise
tables available in a variety of formats (plain ASCII, Markdown and HTML).  A
good point-of-entry for exploring data, both for experienced and new R
users.")
    (license license:gpl2)))

(define-public r-lsei
  (package
    (name "r-lsei")
    (version "1.2-0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "lsei" version))
       (sha256
        (base32
         "1xl06fb3is744pxlh42wx5hn1h0ab1k31wnmsmh0524kxzcyp0a7"))))
    (build-system r-build-system)
    (native-inputs
     `(("gfortran" ,gfortran)))
    (home-page "https://www.stat.auckland.ac.nz/~yongwang")
    (synopsis "Solve regression problems under equality/inequality constraints")
    (description
     "It contains functions that solve least squares linear regression
problems under linear equality/inequality constraints.  Functions for solving
quadratic programming problems are also available, which transform such
problems into least squares ones first.")
    (license license:gpl2+)))

(define-public r-npsurv
  (package
    (name "r-npsurv")
    (version "0.4-0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "npsurv" version))
       (sha256
        (base32
         "1wq4c9yfha5azjhrn40iiqkshmvh611sa90jp3lh82n4bl9zfk20"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-lsei" ,r-lsei)))
    (home-page "https://www.stat.auckland.ac.nz/~yongwang")
    (synopsis "Nonparametric survival analysis")
    (description
     "This package contains functions for non-parametric survival analysis of
exact and interval-censored observations.")
    (license license:gpl2+)))

(define-public r-clusteval
  (package
    (name "r-clusteval")
    (version "0.1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "clusteval" version))
       (sha256
        (base32
         "1ld0bdl4fy8dsfzm3k7a37cyxc6pfc9qs31x4pxd3z5rslghz7rj"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-mvtnorm" ,r-mvtnorm)
       ("r-rcpp" ,r-rcpp)))
    (home-page "https://cran.r-project.org/web/packages/clusteval/")
    (synopsis "Evaluation of clustering algorithms")
    (description
     "This R package provides a suite of tools to evaluate clustering
algorithms, clusterings, and individual clusters.")
    (license license:expat)))

(define-public r-tweedie
  (package
    (name "r-tweedie")
    (version "2.3.2")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "tweedie" version))
       (sha256
        (base32
         "10fv998qjxsyx0h94fi0xbh6xbf24nwgh254n9zfnmix9vk2cqls"))))
    (build-system r-build-system)
    (native-inputs `(("gfortran" ,gfortran)))
    (home-page "https://cran.r-project.org/web/packages/tweedie/")
    (synopsis "Evaluation of Tweedie exponential family models")
    (description
     "Maximum likelihood computations for Tweedie families, including the
series expansion (Dunn and Smyth, 2005; <doi10.1007/s11222-005-4070-y>) and
the Fourier inversion (Dunn and Smyth, 2008; <doi:10.1007/s11222-007-9039-6>),
and related methods.")
    (license license:gpl2+)))

(define-public r-rcppgsl
  (package
    (name "r-rcppgsl")
    (version "0.3.7")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "RcppGSL" version))
       (sha256
        (base32 "0cnw2k7cfqrm79r6j283aybflxig80x4n4rjkfp2317wf10mrsa5"))))
    (properties `((upstream-name . "RcppGSL")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-rcpp" ,r-rcpp)
       ("gsl" ,gsl)))
    (native-inputs
     `(("r-knitr" ,r-knitr)))           ; for vignettes
    (home-page "https://cran.r-project.org/web/packages/RcppGSL/")
    (synopsis "Rcpp integration for GSL vectors and matrices")
    (description
     "The GNU Scientific Library (or GSL) is a collection of numerical
routines for scientific computing.  It is particularly useful for C and C++
programs as it provides a standard C interface to a wide range of mathematical
routines.  There are over 1000 functions in total with an extensive test
suite.  The RcppGSL package provides an easy-to-use interface between GSL data
structures and R using concepts from Rcpp which is itself a package that eases
the interfaces between R and C++.")
    (license license:gpl2+)))

(define-public r-mvabund
  (package
    (name "r-mvabund")
    (version "4.1.3")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "mvabund" version))
       (sha256
        (base32
         "1z58h4dk3mc2hfnfvc7pghk471cbp7ah2s1z2ria5igw4s80962b"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-mass" ,r-mass)
       ("r-rcpp" ,r-rcpp)
       ("r-rcppgsl" ,r-rcppgsl)
       ("r-statmod" ,r-statmod)
       ("r-tweedie" ,r-tweedie)))
    (home-page "https://cran.r-project.org/web/packages/mvabund/")
    (synopsis "Statistical methods for analysing multivariate abundance data")
    (description
     "This package provides a set of tools for displaying, modeling and
analysing multivariate abundance data in community ecology.")
    (license license:lgpl2.1+)))

(define-public r-afex
  (package
    (name "r-afex")
    (version "0.27-2")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "afex" version))
       (sha256
        (base32
         "0qsmcddy4449qjj3ajmqvdiqdkhkswmz5dqf150wxwq897p3bvf2"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-car" ,r-car)
       ("r-lme4" ,r-lme4)
       ("r-lmertest" ,r-lmertest)
       ("r-pbkrtest" ,r-pbkrtest)
       ("r-reshape2" ,r-reshape2)))
    (native-inputs
     `(("r-knitr" ,r-knitr)))
    (home-page "https://afex.singmann.science/")
    (synopsis "Analysis of factorial experiments")
    (description
     "This package provides convenience functions for analyzing factorial
experiments using ANOVA or mixed models.")
    (license license:gpl2+)))

(define-public r-lmertest
  (package
    (name "r-lmertest")
    (version "3.1-1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "lmerTest" version))
       (sha256
        (base32
         "0r2vvs3nl6p8xla3gd943khb4ixp0alvspqpnz2y6n3wk8zgh3jj"))))
    (properties `((upstream-name . "lmerTest")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-ggplot2" ,r-ggplot2)
       ("r-lme4" ,r-lme4)
       ("r-mass" ,r-mass)
       ("r-numderiv" ,r-numderiv)))
    (home-page "https://github.com/runehaubo/lmerTestR")
    (synopsis "Tests in linear mixed effects models")
    (description
     "This package provides p-values in type I, II or III anova and summary
tables for @code{lmer} model fits via Satterthwaite's degrees of freedom
method.  A Kenward-Roger method is also available via the @code{pbkrtest}
package.  Model selection methods include step, drop1 and anova-like tables
for random effects (ranova).  Methods for Least-Square means (LS-means) and
tests of linear contrasts of fixed effects are also available.")
    (license license:gpl2+)))

(define-public r-r2glmm
  (package
    (name "r-r2glmm")
    (version "0.1.2")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "r2glmm" version))
       (sha256
        (base32
         "0iim92blpa59vgz97c2pi05yhbjjmaffdbkbmk5kplfb2vmazgiy"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-afex" ,r-afex)
       ("r-data-table" ,r-data-table)
       ("r-dplyr" ,r-dplyr)
       ("r-ggplot2" ,r-ggplot2)
       ("r-gridextra" ,r-gridextra)
       ("r-lmertest" ,r-lmertest)
       ("r-mass" ,r-mass)
       ("r-matrix" ,r-matrix)
       ("r-mgcv" ,r-mgcv)
       ("r-pbkrtest" ,r-pbkrtest)))
    (home-page "https://github.com/bcjaeger/r2glmm")
    (synopsis "Compute R squared for mixed (multilevel) models")
    (description
     "This package computes model and semi partial R squared with confidence
limits for the linear and generalized linear mixed model (LMM and GLMM).  The
R squared measure from L. J. Edwards et al. (2008) is extended to the GLMM
using @dfn{penalized quasi-likelihood} (PQL) estimation (see Jaeger et
al. (2016)).")
    (license license:gpl2)))

(define-public r-weights
  (package
    (name "r-weights")
    (version "1.0.1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "weights" version))
       (sha256
        (base32
         "1ka2kvzg464vn80qziqy4mrciy9wwd3jfasgq0d33wbiblhmxkj5"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-gdata" ,r-gdata)
       ("r-hmisc" ,r-hmisc)
       ("r-mice" ,r-mice)))
    (home-page
     "https://cran.r-project.org/web/packages/weights/")
    (synopsis "Weighting and weighted statistics")
    (description "This package Provides a variety of functions for producing
simple weighted statistics, such as weighted Pearson's correlations, partial
correlations, Chi-Squared statistics, histograms, and t-tests.  Also now
includes some software for quickly recoding survey data and plotting point
estimates from interaction terms in regressions (and multiply imputed
regressions).  NOTE: Weighted partial correlation calculations pulled to
address a bug.")
  (license license:gpl2+)))

(define-public r-rcppannoy
  (package
    (name "r-rcppannoy")
    (version "0.0.16")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "RcppAnnoy" version))
       (sha256
        (base32
         "0bfa35lp6vc4b0h3ymvdx50br233q8vvyjml34ngi81rj0imz3fr"))))
    (properties `((upstream-name . "RcppAnnoy")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-rcpp" ,r-rcpp)))
    (home-page "https://cran.r-project.org/web/packages/RcppAnnoy/")
    (synopsis "Rcpp bindings for Annoy, a library for Approximate Nearest Neighbors")
    (description
     "Annoy is a small C++ library for Approximate Nearest Neighbors written
for efficient memory usage as well an ability to load from and save to disk.
This package provides an R interface.")
    ;; Annoy is released under ASL 2.0, but this wrapper is released under
    ;; GPLv2+.
    (license (list license:gpl2+ license:asl2.0))))

(define-public r-rcpphnsw
  (package
    (name "r-rcpphnsw")
    (version "0.2.0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "RcppHNSW" version))
       (sha256
        (base32
         "0gqdkw7vkcm544rz45g0hplg836ygzbfwk9gh9wr0817icvdb3qv"))))
    (properties `((upstream-name . "RcppHNSW")))
    (build-system r-build-system)
    (propagated-inputs `(("r-rcpp" ,r-rcpp)))
    (home-page "https://cran.r-project.org/web/packages/RcppHNSW/")
    (synopsis "Rcpp bindings for hnswlib, a library for approximate nearest neighbors")
    (description
     "Hnswlib is a C++ library for approximate nearest neighbors.  This
package provides a minimal R interface by relying on the Rcpp package.")
    ;; hnswlib is released under Version 2.0 of the Apache License.
    (license (list license:gpl3 license:asl2.0))))

(define-public r-rcppparallel
  (package
    (name "r-rcppparallel")
    (version "5.0.0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "RcppParallel" version))
       (sha256
        (base32
         "1mhd6vp47xmfw533h0pkvydv96m57fspvd85g8m7iqb5rcxvhhdb"))))
    (properties `((upstream-name . "RcppParallel")))
    (build-system r-build-system)
    (home-page "https://rcppcore.github.io/RcppParallel/")
    (synopsis "Parallel programming tools for Rcpp")
    (description
     "This package provides high level functions for parallel programming with
Rcpp.  For example, the @code{parallelFor()} function can be used to convert
the work of a standard serial @code{for} loop into a parallel one and the
@code{parallelReduce()} function can be used for accumulating aggregates or
other values.")
    (license license:gpl2)))

(define-public r-ncdf4
  (package
    (name "r-ncdf4")
    (version "1.17")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "ncdf4" version))
       (sha256
        (base32
         "1xls44ln2zjrrlimxl8v4bk2ni3g45c9j0gxdnjx31rikmrc95fv"))))
    (build-system r-build-system)
    (inputs
     `(("netcdf" ,netcdf)
       ("zlib" ,zlib)))
    (home-page "https://cran.r-project.org/web/packages/ncdf4/index.html")
    (synopsis "R interface to Unidata netCDF format data files")
    (description
     "This package provides a high-level R interface to data files written
using Unidata's netCDF library (version 4 or earlier), which are binary data
files that are portable across platforms and include metadata information in
addition to the data sets.  Using this package, netCDF files can be opened and
data sets read in easily.  It is also easy to create new netCDF dimensions,
variables, and files, in either version 3 or 4 format, and manipulate existing
netCDF files.")
    (license license:gpl3+)))

(define-public r-biocmanager
  (package
    (name "r-biocmanager")
    (version "1.30.10")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "BiocManager" version))
       (sha256
        (base32 "03n9s2vf7vgpgb5alpxwamf9xfkn32cbzngwyn6spq1bnh9a9dzk"))))
    (properties `((upstream-name . "BiocManager")))
    (build-system r-build-system)
    (home-page "https://cran.r-project.org/web/packages/BiocManager/")
    (synopsis "Access the Bioconductor project package repository")
    (description
     "This package provides a convenient tool to install and update
Bioconductor packages.")
    (license license:artistic2.0)))

(define-public r-rgl
  (package
    (name "r-rgl")
    (version "0.100.50")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "rgl" version))
       (sha256
        (base32
         "165p932ml7dpjkm41zc47p5cdxar69il0m5yvg0avi8q01vr17ay"))))
    (build-system r-build-system)
    (native-inputs
     `(("pkg-config" ,pkg-config)))
    (inputs
     `(("freetype" ,freetype)
       ("libpng" ,libpng)
       ("glu" ,glu)
       ("libx11" ,libx11)
       ("ghc-pandoc" ,ghc-pandoc)
       ("zlib" ,zlib)))
    (propagated-inputs
     `(("r-crosstalk" ,r-crosstalk)
       ("r-htmltools" ,r-htmltools)
       ("r-htmlwidgets" ,r-htmlwidgets)
       ("r-jsonlite" ,r-jsonlite)
       ("r-knitr" ,r-knitr)
       ("r-magrittr" ,r-magrittr)
       ("r-manipulatewidget" ,r-manipulatewidget)
       ("r-shiny" ,r-shiny)))
    (home-page "https://r-forge.r-project.org/projects/rgl/")
    (synopsis "3D visualization using OpenGL")
    (description
     "This package provides medium to high level functions for 3D interactive graphics,
including functions modelled on base graphics (@code{plot3d()}, etc.) as well
as functions for constructing representations of geometric
objects (@code{cube3d()}, etc.).  Output may be on screen using OpenGL, or to
various standard 3D file formats including WebGL, PLY, OBJ, STL as well as 2D
image formats, including PNG, Postscript, SVG, PGF.")
    ;; Any version of the GPL.
    (license (list license:gpl2+ license:gpl3+))))

(define-public r-multicool
  (package
    (name "r-multicool")
    (version "0.1-11")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "multicool" version))
       (sha256
        (base32
         "0xk408qbz9cxwf51j3pmy55gcjcnws8mc6j3vyn9zhramxj7x40w"))))
    (build-system r-build-system)
    (propagated-inputs `(("r-rcpp" ,r-rcpp)))
    (home-page "https://cran.r-project.org/web/packages/multicool/")
    (synopsis "Permutations of multisets in cool-lex order")
    (description
     "This package provides a set of tools to permute multisets without loops
or hash tables and to generate integer partitions.  Cool-lex order is similar
to colexicographical order.")
    (license license:gpl2)))

(define-public r-misc3d
  (package
    (name "r-misc3d")
    (version "0.8-4")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "misc3d" version))
       (sha256
        (base32
         "0qjzpw3h09qi2gfz52b7nhzd95p7yyxsd03fldc9wzzn6wi3vpkm"))))
    (build-system r-build-system)
    (home-page "https://cran.r-project.org/web/packages/misc3d/")
    (synopsis "Miscellaneous 3D Plots")
    (description
     "This package provides a collection of miscellaneous 3d plots, including
isosurfaces.")
    ;; Any version of the GPL.
    (license (list license:gpl2+ license:gpl3+))))

(define-public r-ks
  (package
    (name "r-ks")
    (version "1.11.7")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "ks" version))
       (sha256
        (base32 "1f6jvxy0hmngyvnvrknzbmhl42njk0vqyycvydm4qnp8cqirqvba"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-fnn" ,r-fnn)
       ("r-kernlab" ,r-kernlab)
       ("r-kernsmooth" ,r-kernsmooth)
       ("r-matrix" ,r-matrix)
       ("r-mclust" ,r-mclust)
       ("r-mgcv" ,r-mgcv)
       ("r-multicool" ,r-multicool)
       ("r-mvtnorm" ,r-mvtnorm)))
    (home-page "http://www.mvstat.net/tduong/")
    (synopsis "Kernel smoothing")
    (description
     "This package provides kernel smoothers for univariate and multivariate
data, including density functions, density derivatives, cumulative
distributions, modal clustering, discriminant analysis, and two-sample
hypothesis testing.")
    ;; Either version of the GPL.
    (license (list license:gpl2 license:gpl3))))

(define-public r-feature
  (package
    (name "r-feature")
    (version "1.2.13")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "feature" version))
       (sha256
        (base32
         "07hkw0bv38naj2hdsx4xxrm2dngi6w3rbvgr7s50bjic8hlgy1ra"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-ks" ,r-ks)
       ("r-misc3d" ,r-misc3d)
       ("r-rgl" ,r-rgl)))
    (home-page "http://www.mvstat.net/tduong/")
    (synopsis "Inferential feature significance for kernel density estimation")
    (description
     "The feature package contains functions to display and compute kernel
density estimates, significant gradient and significant curvature regions.
Significant gradient and/or curvature regions often correspond to significant
features (e.g. local modes).")
    ;; Either version of the GPL.
    (license (list license:gpl2 license:gpl3))))

(define-public r-arm
  (package
    (name "r-arm")
    (version "1.10-1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "arm" version))
       (sha256
        (base32
         "0vvp90jygajd6ydky57z66wqjq9msfbl88irj5jbsray574mh4bg"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-abind" ,r-abind)
       ("r-coda" ,r-coda)
       ("r-lme4" ,r-lme4)
       ("r-mass" ,r-mass)
       ("r-matrix" ,r-matrix)
       ("r-nlme" ,r-nlme)))
    (home-page "https://cran.r-project.org/web/packages/arm/")
    (synopsis "Data analysis using regression and multilevel/hierarchical models")
    (description
     "This package provides functions to accompany A. Gelman and J. Hill,
Data Analysis Using Regression and Multilevel/Hierarchical Models, Cambridge
University Press, 2007.")
    (license license:gpl3+)))

(define-public r-circular
  (package
    (name "r-circular")
    (version "0.4-93")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "circular" version))
       (sha256
        (base32
         "0hki85rs8wc5950pjaw28q54rly2napfbcrx3pchlfap6wwy5kkn"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-boot" ,r-boot)
       ("r-mvtnorm" ,r-mvtnorm)))
    (native-inputs
     `(("gfortran" ,gfortran)))
    (home-page "https://cran.r-project.org/web/packages/circular/")
    (synopsis "Circular statistics")
    (description
     "This package provides tools for circular statistics, from \"Topics in
circular Statistics\" (2001) S. Rao Jammalamadaka and A. SenGupta, World
Scientific.")
    (license license:gpl2+)))

(define-public r-activity
  (package
    (name "r-activity")
    (version "1.3")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "activity" version))
       (sha256
        (base32
         "12imqj366dp6pam5gap6ji56p5wf1073xz5g4iikfxf5l8snxw92"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-circular" ,r-circular)
       ("r-insol" ,r-insol)
       ("r-pbapply" ,r-pbapply)))
    (home-page "https://cran.r-project.org/web/packages/activity/")
    (synopsis "Animal activity statistics")
    (description
     "This package provides functions to fit kernel density functions to
animal activity time data; plot activity distributions; quantify overall
levels of activity; statistically compare activity metrics through
bootstrapping; and evaluate variation in linear variables with time (or other
circular variables).")
    (license license:gpl3)))

(define-public r-ouch
  (package
    (name "r-ouch")
    (version "2.14-1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "ouch" version))
       (sha256
        (base32
         "0ddf9bw5lhj8vb0ja78jf99i0smq4rgmm842k4a4ygap41vdyn2b"))))
    (build-system r-build-system)
    (propagated-inputs `(("r-subplex" ,r-subplex)))
    (home-page "https://kingaa.github.io/ouch/")
    (synopsis "Ornstein-Uhlenbeck models for phylogenetic comparative hypotheses")
    (description
     "This package provides tools to fit and compare Ornstein-Uhlenbeck models
for evolution along a phylogenetic tree.")
    (license license:gpl2+)))

(define-public r-fmsb
  (package
    (name "r-fmsb")
    (version "0.7.0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "fmsb" version))
       (sha256
        (base32
         "0x1wkzfdvv4s5xmr0whcwjz4aac71gacwymj2c3mzj2bbswwlw45"))))
    (build-system r-build-system)
    (home-page "http://minato.sip21c.org/msb/")
    (synopsis "Functions for medical statistics book with demographic data")
    (description
     "This package provides several utility functions for the book entitled
\"Practices of Medical and Health Data Analysis using R\" (Pearson Education
Japan, 2007) with Japanese demographic data and some demographic analysis
related functions.")
    (license license:gpl2+)))

(define-public r-stabledist
  (package
    (name "r-stabledist")
    (version "0.7-1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "stabledist" version))
       (sha256
        (base32
         "0scar396wiq6wkbkvwp4qrxqc1m075y56p37i6iry5rw796p1i86"))))
    (build-system r-build-system)
    (home-page "https://www.rmetrics.org")
    (synopsis "Stable distribution functions")
    (description
     "This package provides density, probability and quantile functions, and
random number generation for (skew) stable distributions, using the
parametrizations of Nolan.")
    (license license:gpl2+)))

(define-public r-gsl
  (package
    (name "r-gsl")
    (version "2.1-6")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "gsl" version))
       (sha256
        (base32
         "0p4rh7npp6qbfc5sxjq86xjn7c9ivf3pd60qf1hldwckjqin7m7m"))))
    (build-system r-build-system)
    (inputs
     `(("gsl" ,gsl)))
    (home-page "https://cran.r-project.org/web/packages/gsl")
    (synopsis "Wrapper for the GNU Scientific Library")
    (description
     "This package provides an R wrapper for the special functions and quasi
random number generators of the GNU Scientific Library.")
    (license license:gpl2+)))

(define-public r-adgoftest
  (package
    (name "r-adgoftest")
    (version "0.3")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "ADGofTest" version))
       (sha256
        (base32
         "0ik817qzqp6kfbckjp1z7srlma0w6z2zcwykh0jdiv7nahwk3ncw"))))
    (properties `((upstream-name . "ADGofTest")))
    (build-system r-build-system)
    (home-page "https://cran.r-project.org/web/packages/ADGofTest")
    (synopsis "Anderson-Darling GoF test")
    (description
     "This package provides an implementation of the Anderson-Darling GoF test
with p-value calculation based on Marsaglia's 2004 paper \"Evaluating the
Anderson-Darling Distribution\".")
    ;; Any version of the GPL.
    (license license:gpl3+)))

(define-public r-softimpute
  (package
    (name "r-softimpute")
    (version "1.4")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "softImpute" version))
       (sha256
        (base32
         "07cxbzkl08q58m1455i139952rmryjlic4s2f2hscl5zxxmfdxcq"))))
    (properties `((upstream-name . "softImpute")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-matrix" ,r-matrix)))
    (native-inputs
     `(("gfortran" ,gfortran)))
    (home-page "https://cran.r-project.org/web/packages/softImpute")
    (synopsis "Matrix completion via iterative soft-thresholded SVD")
    (description
     "This package provides iterative methods for matrix completion that use
nuclear-norm regularization.  The package includes procedures for centering
and scaling rows, columns or both, and for computing low-rank @dfn{single
value decompositions} (SVDs) on large sparse centered matrices (i.e. principal
components).")
    (license license:gpl2)))

(define-public r-fftwtools
  (package
    (name "r-fftwtools")
    (version "0.9-8")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "fftwtools" version))
       (sha256
        (base32
         "1nqvpzda281rxi1cmwajxxsn3sc3gz7scv8bvs5jm34kf36whha6"))))
    (build-system r-build-system)
    (inputs `(("fftw" ,fftw)))
    (home-page "https://github.com/krahim/fftwtools")
    (synopsis "Wrapper for FFTW3")
    (description
     "This package provides a wrapper for several FFTW functions.  It provides
access to the two-dimensional FFT, the multivariate FFT, and the
one-dimensional real to complex FFT using the FFTW3 library.  The package
includes the functions @code{fftw()} and @code{mvfftw()} which are designed to
mimic the functionality of the R functions @code{fft()} and @code{mvfft()}.
The FFT functions have a parameter that allows them to not return the
redundant complex conjugate when the input is real data.")
    (license license:gpl2+)))

(define-public r-tiff
  (package
    (name "r-tiff")
    (version "0.1-5")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "tiff" version))
       (sha256
        (base32
         "0asf2bws3x3yd3g3ixvk0f86b0mdf882pl8xrqlxrkbgjalyc54m"))))
    (build-system r-build-system)
    (inputs
     `(("libtiff" ,libtiff)
       ("libjpeg" ,libjpeg)
       ("zlib" ,zlib)))
    (home-page "https://www.rforge.net/tiff/")
    (synopsis "Read and write TIFF images")
    (description
     "This package provides an easy and simple way to read, write and display
bitmap images stored in the TIFF format.  It can read and write both files and
in-memory raw vectors.")
    ;; Either of these two license versions.
    (license (list license:gpl2 license:gpl3))))

(define-public r-nlp
  (package
    (name "r-nlp")
    (version "0.2-0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "NLP" version))
       (sha256
        (base32
         "0xbhkrnxcbf322jfw31xcn4y2gnk5y7ccq1bz4h3prf44h0whr7w"))))
    (properties `((upstream-name . "NLP")))
    (build-system r-build-system)
    (home-page "https://cran.r-project.org/web/packages/NLP/")
    (synopsis "Natural language processing infrastructure")
    (description
     "This package provides basic classes and methods for Natural Language
Processing.")
    (license license:gpl3)))

(define-public r-tm
  (package
    (name "r-tm")
    (version "0.7-7")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "tm" version))
       (sha256
        (base32
         "0pyics8j7a4wkh5gzin46l0qars5vgbb1886xqpdqjs1z0gy9nyh"))))
    (properties `((upstream-name . "tm")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-bh" ,r-bh)
       ("r-nlp" ,r-nlp)
       ("r-rcpp" ,r-rcpp)
       ("r-slam" ,r-slam)
       ("r-xml2" ,r-xml2)))
    (home-page "http://tm.r-forge.r-project.org/")
    (synopsis "Text mining package")
    (description
     "This package provides a framework for text mining applications within R.")
    (license license:gpl3)))

(define-public r-waveslim
  (package
    (name "r-waveslim")
    (version "1.8.2")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "waveslim" version))
       (sha256
        (base32
         "0ibivnhz0l06sss5rrrcvyiwg3qpbyk3qn4vx4pp90kj09x4yg0k"))))
    (build-system r-build-system)
    (native-inputs
     `(("gfortran" ,gfortran)))
    (home-page "http://waveslim.blogspot.com")
    (synopsis "Basic wavelet routines for signal processing")
    (description
     "This package provides basic wavelet routines for time series (1D),
image (2D) and array (3D) analysis.  The code provided here is based on
wavelet methodology developed in Percival and Walden (2000); Gencay, Selcuk
and Whitcher (2001); the dual-tree complex wavelet transform (DTCWT) from
Kingsbury (1999, 2001) as implemented by Selesnick; and Hilbert wavelet
pairs (Selesnick 2001, 2002).")
    (license license:bsd-3)))

(define-public r-wordcloud
  (package
    (name "r-wordcloud")
    (version "2.6")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "wordcloud" version))
       (sha256
        (base32
         "0j96yyvm6bcrrpbdx4w26piqx44a0vbsr3px9cb4zk8a8da6jwak"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-rcolorbrewer" ,r-rcolorbrewer)
       ("r-rcpp" ,r-rcpp)
       ;; The "tm" package is only "suggested" according to CRAN, but the
       ;; wordcloud package cannot be loaded without it.
       ("r-tm" ,r-tm)))
    (home-page "https://cran.r-project.org/web/packages/wordcloud")
    (synopsis "Word clouds")
    (description
     "This package provides functionality to create pretty word clouds,
visualize differences and similarity between documents, and avoid
over-plotting in scatter plots with text.")
    (license license:lgpl2.1)))

(define-public r-colorramps
  (package
    (name "r-colorramps")
    (version "2.3")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "colorRamps" version))
       (sha256
        (base32
         "0shbjh83x1axv4drm5r3dwgbyv70idih8z4wlzjs4hiac2qfl41z"))))
    (properties `((upstream-name . "colorRamps")))
    (build-system r-build-system)
    (home-page "https://cran.r-project.org/web/packages/colorRamps")
    (synopsis "Build color tables")
    (description "This package provides features to build gradient color
maps.")
    ;; Any version of the GPL
    (license license:gpl3+)))

(define-public r-tidytree
  (package
    (name "r-tidytree")
    (version "0.3.3")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "tidytree" version))
       (sha256
        (base32 "05b53dap0f784kl6s1wgck6m7brwmy6ifqp7v5l06s1spfspagl6"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-ape" ,r-ape)
       ("r-dplyr" ,r-dplyr)
       ("r-lazyeval" ,r-lazyeval)
       ("r-magrittr" ,r-magrittr)
       ("r-rlang" ,r-rlang)
       ("r-tibble" ,r-tibble)))
    (native-inputs
     `(("r-knitr" ,r-knitr)))
    (home-page "https://github.com/GuangchuangYu/tidytree")
    (synopsis "Tidy tool for phylogenetic tree data manipulation")
    (description
     "Phylogenetic trees generally contain multiple components including nodes,
edges, branches and associated data.  This package provides an approach to
convert tree objects to tidy data frames.  It also provides tidy interfaces to
manipulate tree data.")
    (license license:artistic2.0)))

(define-public r-rvcheck
  (package
    (name "r-rvcheck")
    (version "0.1.8")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "rvcheck" version))
       (sha256
        (base32 "0627bc8qmhxmd63yh6f90qni3qw1zwdpxjln2qbychzmzd4am9ac"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-biocmanager" ,r-biocmanager)
       ("r-rlang" ,r-rlang)))
    (home-page "https://cran.r-project.org/web/packages/rvcheck")
    (synopsis "R package version check")
    (description
     "This package provides tools to check the latest release version of R and
R packages (on CRAN, Bioconductor or Github).")
    (license license:artistic2.0)))

(define-public r-docopt
  (package
    (name "r-docopt")
    (version "0.6.1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "docopt" version))
       (sha256
        (base32
         "06zknnd0c5s2y0hbddzdlr3m63ib783izpck6pgz7sjbab5pd068"))))
    (build-system r-build-system)
    (home-page "https://github.com/docopt/docopt.R")
    (synopsis "Command-line interface specification language")
    (description
     "This package enables you to define a command-line interface by just
giving it a description in the specific format.")
    (license license:expat)))

(define-public r-sparsesvd
  (package
    (name "r-sparsesvd")
    (version "0.2")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "sparsesvd" version))
       (sha256
        (base32
         "1xm969fjq3fv1p2sqza2apz8picibj4s2agpwf1sx9nwn3b587qs"))))
    (build-system r-build-system)
    (propagated-inputs `(("r-matrix" ,r-matrix)))
    (home-page "http://tedlab.mit.edu/~dr/SVDLIBC/")
    (synopsis "Sparse truncated singular value decomposition")
    (description
     "This package provides a Wrapper around the SVDLIBC library
for (truncated) singular value decomposition of a sparse matrix.  Currently,
only sparse real matrices in Matrix package format are supported.")
    ;; SVDLIBC is released under BSD-2.  The R interface is released under
    ;; BSD-3.
    (license (list license:bsd-3 license:bsd-2))))

(define-public r-speedglm
  (package
    (name "r-speedglm")
    (version "0.3-2")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "speedglm" version))
       (sha256
        (base32
         "1b25zimk0z7ad62yacqdg0zk0qs0jja4i918ym942xfw4j1z3jjz"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-mass" ,r-mass)
       ("r-matrix" ,r-matrix)))
    (home-page "https://cran.r-project.org/web/packages/speedglm")
    (synopsis "Fit linear and generalized linear models to large data sets")
    (description
     "This package provides tools for fitting linear models and generalized
linear models to large data sets by updating algorithms.")
    ;; Any version of the GPL
    (license license:gpl2+)))

(define-public r-densityclust
  (package
    (name "r-densityclust")
    (version "0.3")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "densityClust" version))
       (sha256
        (base32
         "1zry0vafajzmr37aylglxfvwplhdygbkb9cvzvh8cy0xgnjrnx13"))))
    (properties `((upstream-name . "densityClust")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-fnn" ,r-fnn)
       ("r-ggplot2" ,r-ggplot2)
       ("r-ggrepel" ,r-ggrepel)
       ("r-gridextra" ,r-gridextra)
       ("r-rcolorbrewer" ,r-rcolorbrewer)
       ("r-rcpp" ,r-rcpp)
       ("r-rtsne" ,r-rtsne)))
    (home-page "https://cran.r-project.org/web/packages/densityClust")
    (synopsis "Clustering by fast search and find of density peaks")
    (description
     "This package provides an improved implementation (based on k-nearest
neighbors) of the density peak clustering algorithm, originally described by
Alex Rodriguez and Alessandro Laio (Science, 2014 vol. 344).  It can handle
large datasets (> 100,000 samples) very efficiently.")
    (license license:gpl2+)))

(define-public r-combinat
  (package
    (name "r-combinat")
    (version "0.0-8")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "combinat" version))
       (sha256
        (base32
         "1h9hr88gigihc4na7lb5i7rn4az1xa7sb34zvnznaj6pdrmwy4qm"))))
    (build-system r-build-system)
    (home-page "https://cran.r-project.org/web/packages/combinat")
    (synopsis "Combinatorics utilities")
    (description "This package provides assorted routines for combinatorics.")
    (license license:gpl2)))

(define-public r-qlcmatrix
  (package
    (name "r-qlcmatrix")
    (version "0.9.7")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "qlcMatrix" version))
       (sha256
        (base32
         "0iqkcvvy8rxlk0s83sjq57dd6fadb18p5z31lzy0gnzv1hsy1x8y"))))
    (properties `((upstream-name . "qlcMatrix")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-docopt" ,r-docopt)
       ("r-matrix" ,r-matrix)
       ("r-slam" ,r-slam)
       ("r-sparsesvd" ,r-sparsesvd)))
    (home-page "https://cran.r-project.org/web/packages/qlcMatrix")
    (synopsis "Sparse matrix functions for quantitative language comparison")
    (description
     "This package provides an extension of the functionality of the Matrix
package for using sparse matrices.  Some of the functions are very general,
while other are highly specific for the special data format used for
@dfn{quantitative language comparison} (QLC).")
    (license license:gpl3)))

(define-public r-ddrtree
  (package
    (name "r-ddrtree")
    (version "0.1.5")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "DDRTree" version))
       (sha256
        (base32
         "16s5fjw7kwlxhrkzdny62sx32fvmg3rxjc3wrh6krd31jh1fqlfk"))))
    (properties `((upstream-name . "DDRTree")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-bh" ,r-bh)
       ("r-irlba" ,r-irlba)
       ("r-rcpp" ,r-rcpp)
       ("r-rcppeigen" ,r-rcppeigen)))
    (home-page "https://cran.r-project.org/web/packages/DDRTree")
    (synopsis "Learning principal graphs with DDRTree")
    (description
     "This package provides an implementation of the framework of
@dfn{reversed graph embedding} (RGE) which projects data into a reduced
dimensional space while constructs a principal tree which passes through the
middle of the data simultaneously.  DDRTree shows superiority to
alternatives (Wishbone, DPT) for inferring the ordering as well as the
intrinsic structure of single cell genomics data.  In general, it could be
used to reconstruct the temporal progression as well as the bifurcation
structure of any data type.")
    (license license:asl2.0)))

(define-public r-corpcor
  (package
    (name "r-corpcor")
    (version "1.6.9")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "corpcor" version))
       (sha256
        (base32
         "1hi3i9d3841snppq1ks5pd8cliq1b4rm4dpsczmfqvwksg8snkrf"))))
    (build-system r-build-system)
    (home-page "http://strimmerlab.org/software/corpcor/")
    (synopsis "Efficient estimation of covariance and (partial) correlation")
    (description
     "This package implements a James-Stein-type shrinkage estimator for the
covariance matrix, with separate shrinkage for variances and correlations.
Furthermore, functions are available for fast singular value decomposition,
for computing the pseudoinverse, and for checking the rank and positive
definiteness of a matrix.")
    (license license:gpl3+)))

(define-public r-rspectra
  (package
    (name "r-rspectra")
    (version "0.16-0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "RSpectra" version))
       (sha256
        (base32
         "1ab45as2ysjrvkhvmx7y3nbhd0y1w4j9k2a789lcd973zz4wzwda"))))
    (properties `((upstream-name . "RSpectra")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-matrix" ,r-matrix)
       ("r-rcpp" ,r-rcpp)
       ("r-rcppeigen" ,r-rcppeigen)))
    (home-page "https://github.com/yixuan/RSpectra")
    (synopsis "Solvers for large-scale Eigenvalue and SVD problems")
    (description
     "This package provides an R interface to the Spectra library for
large-scale eigenvalue and SVD problems.  It is typically used to compute a
few eigenvalues/vectors of an n by n matrix, e.g., the k largest eigenvalues,
which is usually more efficient than @code{eigen()} if k << n.")
    ;; MPL 2 or later.
    (license license:mpl2.0)))

(define-public r-vbsr
  (package
    (name "r-vbsr")
    (version "0.0.5")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "vbsr" version))
       (sha256
        (base32
         "1avskbxxyinjjdga4rnghcfvd4sypv4m39ysfaij5avvmi89bx3b"))))
    (build-system r-build-system)
    (home-page "https://cran.r-project.org/web/packages/vbsr")
    (synopsis "Variational Bayes spike regression regularized linear models")
    (description
     "This package provides an efficient algorithm for solving ultra-sparse
regularized regression models using a variational Bayes algorithm with a spike
prior.  The algorithm is solved on a path, with coordinate updates, and is
capable of generating very sparse models.  Very general model
diagnostics for controlling type-1 errors are also provided.")
    (license license:gpl2)))

(define-public r-flare
  (package
    (name "r-flare")
    (version "1.6.0.2")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "flare" version))
       (sha256
        (base32
         "1ybrsx1djqldw0l5l1iz4pfh6xxb8ckkg1ric7wnsr51wm9ljlh5"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-igraph" ,r-igraph)
       ("r-lattice" ,r-lattice)
       ("r-mass" ,r-mass)
       ("r-matrix" ,r-matrix)))
    (home-page "https://cran.r-project.org/web/packages/flare")
    (synopsis "Family of Lasso regression implementations")
    (description
     "This package provides implementations of a family of Lasso variants
including Dantzig Selector, LAD Lasso, SQRT Lasso, Lq Lasso for estimating
high dimensional sparse linear models.")
    (license license:gpl2)))

(define-public r-lassopv
  (package
    (name "r-lassopv")
    (version "0.2.0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "lassopv" version))
       (sha256
        (base32
         "0yawnjw063jypk3riy9xab9cmliv6c9dnabi18670khd3gzb2r9z"))))
    (build-system r-build-system)
    (propagated-inputs `(("r-lars" ,r-lars)))
    (home-page "https://github.com/lingfeiwang/lassopv")
    (synopsis "Non-parametric p-value estimation for predictors in Lasso")
    (description
     "This package enables you to estimate the p-values for predictors x
against target variable y in Lasso regression, using the regularization
strength when each predictor enters the active set of regularization path for
the first time as the statistic.")
    (license license:gpl3)))

(define-public r-splitstackshape
  (package
    (name "r-splitstackshape")
    (version "1.4.8")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "splitstackshape" version))
       (sha256
        (base32
         "0mpyf2kkfdl69pdc6brl1r6101vyc6pgr7z17s55ppg3y71k4q35"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-data-table" ,r-data-table)))
    (home-page "https://github.com/mrdwab/splitstackshape")
    (synopsis "Stack and reshape datasets after splitting concatenated values")
    (description
     "Online data collection tools like Google Forms often export
multiple-response questions with data concatenated in cells.  The
@code{concat.split} (cSplit) family of functions provided by this package
splits such data into separate cells.  This package also includes functions to
stack groups of columns and to reshape wide data, even when the data are
\"unbalanced\"---something which @code{reshape} (from base R) does not handle,
and which @code{melt} and @code{dcast} from @code{reshape2} do not easily
handle.")
    (license license:gpl3)))

(define-public r-tfmpvalue
  (package
    (name "r-tfmpvalue")
    (version "0.0.8")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "TFMPvalue" version))
       (sha256
        (base32
         "0h9qkl15k8v17v3g9bdnfwvh2s04ywjgg5y0xn2077dmywlja1bd"))))
    (properties `((upstream-name . "TFMPvalue")))
    (build-system r-build-system)
    (propagated-inputs `(("r-rcpp" ,r-rcpp)))
    (home-page "https://github.com/ge11232002/TFMPvalue")
    (synopsis "P-value computation for position weight matrices")
    (description
     "In putative @dfn{Transcription Factor Binding Sites} (TFBSs)
identification from sequence/alignments, we are interested in the significance
of certain match scores.  TFMPvalue provides the accurate calculation of a
p-value with a score threshold for position weight matrices, or the score with
a given p-value.  It is an interface to code originally made available by
Helene Touzet and Jean-Stephane Varre, 2007, Algorithms Mol Biol:2, 15.
Touzet and Varre (2007).")
    (license license:gpl2)))

(define-public r-rnifti
  (package
    (name "r-rnifti")
    (version "1.1.0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "RNifti" version))
       (sha256
        (base32
         "1z8ninp3aq18w0slcfn8r2fp48cdz8l0k0namsrnvgyp8lzcpqpn"))))
    (properties `((upstream-name . "RNifti")))
    (build-system r-build-system)
    (propagated-inputs `(("r-rcpp" ,r-rcpp)))
    (home-page "https://github.com/jonclayden/RNifti")
    (synopsis "Fast R and C++ access to NIfTI images")
    (description
     "This package provides very fast read and write access to images stored
in the NIfTI-1 and ANALYZE-7.5 formats, with seamless synchronisation between
compiled C and interpreted R code.  It also provides a C/C++ API that can be
used by other packages.")
    (license license:gpl2)))

(define-public r-shades
  (package
    (name "r-shades")
    (version "1.4.0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "shades" version))
       (sha256
        (base32
         "1zg95sjhrfvbdlfc387g9p0vnb8nb6agdk1mb3wq3kwkm2da0bqj"))))
    (build-system r-build-system)
    (home-page "https://github.com/jonclayden/shades")
    (synopsis "Simple color manipulation")
    (description
     "This package provides functions for easily manipulating colors,
creating color scales and calculating color distances.")
    (license license:bsd-3)))

(define-public r-ore
  (package
    (name "r-ore")
    (version "1.6.3")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "ore" version))
       (sha256
        (base32 "1vh6w3arrhgkfjjjw7ci91xmz4wpfr3cmwd5zkqch89dgn07skkv"))))
    (build-system r-build-system)
    (home-page "https://github.com/jonclayden/ore")
    (synopsis "R interface to the Onigmo regular expression library")
    (description
     "This package provides an alternative to R's built-in functionality for
handling regular expressions, based on the Onigmo library.  It offers
first-class compiled regex objects, partial matching and function-based
substitutions, amongst other features.")
    (license license:bsd-3)))

(define-public r-reportr
  (package
    (name "r-reportr")
    (version "1.3.0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "reportr" version))
       (sha256
        (base32
         "0zynplxqvbmf23cm2rsz3wz2jx6mv55z94mn1k44ny3lx625cnpw"))))
    (build-system r-build-system)
    (propagated-inputs `(("r-ore" ,r-ore)))
    (home-page "https://github.com/jonclayden/reportr")
    (synopsis "General message and error reporting system")
    (description
     "This package provides a system for reporting messages, which offers
certain useful features over the standard R system, such as the incorporation
of output consolidation, message filtering, assertions, expression
substitution, automatic generation of stack traces for debugging, and
conditional reporting based on the current \"output level\".")
    (license license:gpl2)))

(define-public r-tractor-base
  (package
    (name "r-tractor-base")
    (version "3.3.2")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "tractor.base" version))
       (sha256
        (base32
         "0y5gm0y4chl30f5qqq8qiiw4j8g32s4i9xrvyp3cwg902kf2p86i"))))
    (properties `((upstream-name . "tractor.base")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-ore" ,r-ore)
       ("r-reportr" ,r-reportr)
       ("r-rnifti" ,r-rnifti)
       ("r-shades" ,r-shades)))
    (home-page "https://www.tractor-mri.org.uk")
    (synopsis "Read, manipulate and visualize magnetic resonance images")
    (description
     "This package provides functions for working with magnetic resonance
images.  It supports reading and writing of popular file formats (DICOM,
Analyze, NIfTI-1, NIfTI-2, MGH); interactive and non-interactive
visualization; flexible image manipulation; metadata and sparse image
handling.")
    (license license:gpl2)))

(define-public r-grimport
  (package
    (name "r-grimport")
    (version "0.9-3")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "grImport" version))
       (sha256
        (base32
         "109mrdvq06xq3zgn9ngz0c7zzgqkv5zbpvsb2i636vmlk6y4dpkd"))))
    (properties `((upstream-name . "grImport")))
    (build-system r-build-system)
    (inputs
     `(("ghostscript" ,ghostscript)))
    (propagated-inputs
     `(("r-xml" ,r-xml)))
    (home-page "https://cran.r-project.org/web/packages/grImport")
    (synopsis "Convert, import, and draw PostScript pictures")
    (description
     "This package provides functions for converting, importing, and drawing
PostScript pictures in R plots.")
    (license license:gpl2+)))

(define-public r-grimport2
  (package
    (name "r-grimport2")
    (version "0.2-0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "grImport2" version))
       (sha256
        (base32
         "19q0dd8fpp1g4xf6sg5f8dxybwxjfw553ra6wgjd8b74fzca40m1"))))
    (properties `((upstream-name . "grImport2")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-base64enc" ,r-base64enc)
       ("r-jpeg" ,r-jpeg)
       ("r-png" ,r-png)
       ("r-xml" ,r-xml)))
    (home-page "https://cran.r-project.org/web/packages/grImport2/")
    (synopsis "Import SVG graphics")
    (description
     "This package provides functions for importing external vector images and
drawing them as part of R plots.  This package is different from the
@code{grImport} package because, where that package imports PostScript format
images, this package imports SVG format images.  Furthermore, this package
imports a specific subset of SVG, so external images must be preprocessed
using a package like @code{rsvg} to produce SVG that this package can import.
SVG features that are not supported by R graphics, such as gradient fills, can
be imported and then exported via the @code{gridSVG} package.")
    (license license:gpl2+)))

(define-public r-kohonen
  (package
    (name "r-kohonen")
    (version "3.0.10")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "kohonen" version))
       (sha256
        (base32
         "1ck7j13x701g67bx81x7plszz804jfhl1yg42krcj9x88vm5cscr"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-rcpp" ,r-rcpp)))
    (home-page "https://cran.r-project.org/web/packages/kohonen")
    (synopsis "Supervised and unsupervised self-organising maps")
    (description
     "This package provides functions to train @dfn{self-organising
maps} (SOMs).  Also interrogation of the maps and prediction using trained
maps are supported.  The name of the package refers to Teuvo Kohonen, the
inventor of the SOM.")
    (license license:gpl2+)))

(define-public r-nnls
  (package
    (name "r-nnls")
    (version "1.4")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "nnls" version))
       (sha256
        (base32
         "07vcrrxvswrvfiha6f3ikn640yg0m2b4yd9lkmim1g0jmsmpfp8f"))))
    (build-system r-build-system)
    (native-inputs `(("gfortran" ,gfortran)))
    (home-page "https://cran.r-project.org/web/packages/nnls")
    (synopsis "Lawson-Hanson algorithm for non-negative least squares")
    (description
     "This package provides an R interface to the Lawson-Hanson implementation
of an algorithm for @dfn{non-negative least squares} (NNLS).  It also allows
the combination of non-negative and non-positive constraints.")
    (license license:gpl2+)))

(define-public r-iso
  (package
    (name "r-iso")
    (version "0.0-18")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "Iso" version))
       (sha256
        (base32
         "014mm5b1f7i6nwlz3kyg1biph0y542kcx5bd13p68cv5a928qzid"))))
    (properties `((upstream-name . "Iso")))
    (build-system r-build-system)
    (native-inputs `(("gfortran" ,gfortran)))
    (home-page "https://www.stat.auckland.ac.nz/~rolf/")
    (synopsis "Functions to perform isotonic regression")
    (description
     "This package provides support for linear order and unimodal
order (univariate) isotonic regression and bivariate isotonic regression with
linear order on both variables.")
    (license license:gpl2+)))

(define-public r-chemometricswithr
  (package
    (name "r-chemometricswithr")
    (version "0.1.13")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "ChemometricsWithR" version))
       (sha256
        (base32
         "166va1g3m1wv21qkmw4wpz0bsrclh3jih8smxphdc13l9pqgclpq"))))
    (properties
     `((upstream-name . "ChemometricsWithR")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-devtools" ,r-devtools)
       ("r-kohonen" ,r-kohonen)
       ("r-mass" ,r-mass)
       ("r-pls" ,r-pls)))
    (home-page "https://github.com/rwehrens/CWR")
    (synopsis "Chemometrics with R")
    (description
     "This package provides functions and scripts used in the book
\"Chemometrics with R - Multivariate Data Analysis in the Natural Sciences and
Life Sciences\" by Ron Wehrens, Springer (2011).")
    (license license:gpl2+)))

(define-public r-als
  (package
    (name "r-als")
    (version "0.0.6")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "ALS" version))
       (sha256
        (base32
         "1swrn39vy50fazkpf97r7c542gkj6mlvy8gmcxllg7mf2mqx546a"))))
    (properties `((upstream-name . "ALS")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-iso" ,r-iso)
       ("r-nnls" ,r-nnls)))
    (home-page "https://cran.r-project.org/web/packages/ALS")
    (synopsis "Multivariate curve resolution alternating least squares")
    (description
     "Alternating least squares is often used to resolve components
contributing to data with a bilinear structure; the basic technique may be
extended to alternating constrained least squares.  This package provides an
implementation of @dfn{multivariate curve resolution alternating least
squares} (MCR-ALS).

Commonly applied constraints include unimodality, non-negativity, and
normalization of components.  Several data matrices may be decomposed
simultaneously by assuming that one of the two matrices in the bilinear
decomposition is shared between datasets.")
    (license license:gpl2+)))

(define-public r-strucchange
  (package
    (name "r-strucchange")
    (version "1.5-2")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "strucchange" version))
       (sha256
        (base32
         "1y022363a4pp0mnji91sjh1qiyspkh09sybqwj03r9pmwrd7q93x"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-sandwich" ,r-sandwich)
       ("r-zoo" ,r-zoo)))
    (home-page "https://cran.r-project.org/web/packages/strucchange")
    (synopsis "Testing, monitoring, and dating structural changes")
    (description
     "This package provides tools for testing, monitoring and dating
structural changes in (linear) regression models.  It features tests/methods
from the generalized fluctuation test framework as well as from the F
test (Chow test) framework.  This includes methods to fit, plot and test
fluctuation processes (e.g., CUSUM, MOSUM, recursive/moving estimates) and F
statistics, respectively.  It is possible to monitor incoming data online
using fluctuation processes.  Finally, the breakpoints in regression models
with structural changes can be estimated together with confidence intervals.
Emphasis is always given to methods for visualizing the data.")
    ;; Either of these two GPL versions
    (license (list license:gpl2 license:gpl3))))

(define-public r-pixmap
  (package
    (name "r-pixmap")
    (version "0.4-11")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "pixmap" version))
       (sha256
        (base32
         "04klxp6jndw1bp6z40v20fbmdmdpfca2g0czmmmgbkark9s1183g"))))
    (build-system r-build-system)
    (home-page "https://cran.r-project.org/web/packages/pixmap")
    (synopsis "Tools for bitmap images")
    (description
     "This package provides functions for importing, exporting, plotting and
other manipulations of bitmapped images.")
    (license license:gpl2)))

(define-public r-rapidjsonr
  (package
    (name "r-rapidjsonr")
    (version "1.2.0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "rapidjsonr" version))
       (sha256
        (base32
         "07zdirhbzmvq3cp4xn8ngk1lgxbbabzays315zxbs3sxrz6lzjb2"))))
    (build-system r-build-system)
    (home-page "https://cran.r-project.org/web/packages/rapidjsonr")
    (synopsis "JSON parser")
    (description
     "This package provides JSON parsing capability through the Rapidjson
library.")
    (license license:expat)))

(define-public r-ontologyindex
  (package
    (name "r-ontologyindex")
    (version "2.5")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "ontologyIndex" version))
       (sha256
        (base32
         "127hlf0z5fmbgnq4p9h8nvn6p72d2fpcn846zzb99s213421jnry"))))
    (properties `((upstream-name . "ontologyIndex")))
    (build-system r-build-system)
    (home-page "https://cran.r-project.org/web/packages/ontologyIndex")
    (synopsis "Functions for processing ontologies in R")
    (description
     "This package provides functions for reading ontologies into R as lists
and manipulating sets of ontological terms.")
    (license license:gpl2+)))

(define-public r-gargle
  (package
    (name "r-gargle")
    (version "0.4.0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "gargle" version))
       (sha256
        (base32
         "08zhfk2sl342w35i5n2c93ayypg3z0kbl0020l3y9adqka1vazgx"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-fs" ,r-fs)
       ("r-glue" ,r-glue)
       ("r-httr" ,r-httr)
       ("r-jsonlite" ,r-jsonlite)
       ("r-rlang" ,r-rlang)
       ("r-withr" ,r-withr)))
    (home-page "https://gargle.r-lib.org")
    (synopsis "Utilities for working with Google APIs")
    (description
     "This package provides utilities for working with Google APIs.  This
includes functions and classes for handling common credential types and for
preparing, executing, and processing HTTP requests.")
    (license license:expat)))

(define-public r-bigrquery
  (package
    (name "r-bigrquery")
    (version "1.2.0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "bigrquery" version))
       (sha256
        (base32
         "1ggh2gngr5x0g6y7d55y6kvn94anf7qi1bkc28cjmw61hxjq38fb"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-assertthat" ,r-assertthat)
       ("r-bit64" ,r-bit64)
       ("r-curl" ,r-curl)
       ("r-dbi" ,r-dbi)
       ("r-gargle" ,r-gargle)
       ("r-glue" ,r-glue)
       ("r-httr" ,r-httr)
       ("r-jsonlite" ,r-jsonlite)
       ("r-prettyunits" ,r-prettyunits)
       ("r-progress" ,r-progress)
       ("r-rapidjsonr" ,r-rapidjsonr)
       ("r-rcpp" ,r-rcpp)
       ("r-rlang" ,r-rlang)
       ("r-tibble" ,r-tibble)))
    (home-page "https://github.com/rstats-db/bigrquery")
    (synopsis "R interface to Google's BigQuery API")
    (description
     "This package provides an R interface to Google's BigQuery database.")
    (license license:gpl3)))

(define-public r-gmp
  (package
    (name "r-gmp")
    (version "0.5-13.6")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "gmp" version))
       (sha256
        (base32
         "0j2sz2nw41y9306rl1b8hbn0spz7453z5iawcq0bvslyrhc1d9ir"))))
    (build-system r-build-system)
    (arguments
     '(#:phases
       (modify-phases %standard-phases
         (add-after 'unpack 'set-CC
           (lambda _ (setenv "CC" "gcc") #t)))))
    (inputs `(("gmp" ,gmp)))
    (home-page "https://cran.r-project.org/web/packages/gmp")
    (synopsis "Multiple precision arithmetic")
    (description
     "This package supports multiple precision arithmetic (big integers and
rationals, prime number tests, matrix computation), \"arithmetic without
limitations\" using the GNU Multiple Precision library.")
    ;; Any version of the GPL.
    (license license:gpl3+)))

(define-public r-rmpfr
  (package
    (name "r-rmpfr")
    (version "0.8-1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "Rmpfr" version))
       (sha256
        (base32
         "09kw7hyca8xc09r2d88qj81cclar8acaq5q9q5rw9f49iffda0rr"))))
    (properties `((upstream-name . "Rmpfr")))
    (build-system r-build-system)
    (inputs
     `(("mpfr" ,mpfr)
       ("gmp" ,gmp)))
    (propagated-inputs
     `(("r-gmp" ,r-gmp)))
    (native-inputs
     `(("pkg-config" ,pkg-config)))
    (home-page "http://rmpfr.r-forge.r-project.org/")
    (synopsis "R bindings to the MPFR library")
    (description
     "This package supports arithmetic (via S4 classes and methods) for
arbitrary precision floating point numbers, including transcendental
functions.  To this end, the package interfaces with the @dfn{Multiple
Precision Floating-Point Reliable} (MPFR) library.")
    (license license:gpl2+)))

(define-public r-assertive-base
  (package
    (name "r-assertive-base")
    (version "0.0-7")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "assertive.base" version))
       (sha256
        (base32
         "1xs3ysvj0z57c58jw57pckq2rynia6ks4rmjmc02alczhk54wbgh"))))
    (properties
     `((upstream-name . "assertive.base")))
    (build-system r-build-system)
    (home-page "https://bitbucket.org/richierocks/assertive.base")
    (synopsis "Core of the assertive package")
    (description
     "This package provides a minimal set of predicates and assertions used by
the assertive package.  This is mainly for use by other package developers who
want to include run-time testing features in their own packages.")
    (license license:gpl3+)))

(define-public r-assertive-properties
  (package
    (name "r-assertive-properties")
    (version "0.0-4")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "assertive.properties" version))
       (sha256
        (base32
         "0sqs54acs9qk9kvm32rxzfbzxz1l8mjahpfnw7r30z2brgz661jw"))))
    (properties
     `((upstream-name . "assertive.properties")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-assertive-base" ,r-assertive-base)))
    (home-page "https://bitbucket.org/richierocks/assertive.properties")
    (synopsis "Assertions to check properties of variables")
    (description
     "This package provides a set of predicates and assertions for checking
the properties of variables, such as length, names and attributes.  This is
mainly for use by other package developers who want to include run-time
testing features in their own packages.")
    (license license:gpl3+)))

(define-public r-assertive-numbers
  (package
    (name "r-assertive-numbers")
    (version "0.0-2")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "assertive.numbers" version))
       (sha256
        (base32
         "0jc3ss64j4m7bjydhagwwmka5n7c72vpw4kfcch0m5jvkq5qrqds"))))
    (properties
     `((upstream-name . "assertive.numbers")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-assertive-base" ,r-assertive-base)))
    (home-page "https://bitbucket.org/richierocks/assertive.numbers")
    (synopsis "Assertions to check properties of numbers")
    (description
     "This package provides a set of predicates and assertions for checking
the properties of numbers.  This is mainly for use by other package developers
who want to include run-time testing features in their own packages.")
    (license license:gpl3+)))

(define-public r-assertive-sets
  (package
    (name "r-assertive-sets")
    (version "0.0-3")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "assertive.sets" version))
       (sha256
        (base32
         "1cqvh2syvh5b6d85h601zjmsdbbf3h8q98ids4dfl4frdshpasc7"))))
    (properties
     `((upstream-name . "assertive.sets")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-assertive-base" ,r-assertive-base)))
    (home-page "https://bitbucket.org/richierocks/assertive.sets")
    (synopsis "Assertions to check properties of sets")
    (description
     "This package provides a set of predicates and assertions for checking
the properties of sets.  This is mainly for use by other package developers
who want to include run-time testing features in their own packages.")
    (license license:gpl3+)))

(define-public r-assertive-matrices
  (package
    (name "r-assertive-matrices")
    (version "0.0-2")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "assertive.matrices" version))
       (sha256
        (base32
         "16sykzcndv6y2d43x6v9n7m95kv76364h39kh10w4z0xw6ksfqil"))))
    (properties
     `((upstream-name . "assertive.matrices")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-assertive-base" ,r-assertive-base)))
    (home-page "https://bitbucket.org/richierocks/assertive.matrices")
    (synopsis "Assertions to check properties of matrices")
    (description
     "This package provides a set of predicates and assertions for checking
the properties of matrices.  This is mainly for use by other package
developers who want to include run-time testing features in their own
packages.")
    (license license:gpl3+)))

(define-public r-assertive-models
  (package
    (name "r-assertive-models")
    (version "0.0-2")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "assertive.models" version))
       (sha256
        (base32
         "0bn4j4v5qvb2d672cgri61p8d9v258pmz35y3lvm6b9mdxwdi9mr"))))
    (properties
     `((upstream-name . "assertive.models")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-assertive-base" ,r-assertive-base)))
    (home-page "https://bitbucket.org/richierocks/assertive.models")
    (synopsis "Assertions to check properties of models")
    (description
     "This package provides a set of predicates and assertions for checking
the properties of models.  This is mainly for use by other package developers
who want to include run-time testing features in their own packages.")
    (license license:gpl3+)))

(define-public r-assertive-reflection
  (package
    (name "r-assertive-reflection")
    (version "0.0-4")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "assertive.reflection" version))
       (sha256
        (base32
         "19zmsbn00crfqm0kwd9ys5gv87xs3gi6wmlikrz9xiwzm7hp4dhj"))))
    (properties
     `((upstream-name . "assertive.reflection")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-assertive-base" ,r-assertive-base)))
    (home-page "https://bitbucket.org/richierocks/assertive.reflection")
    (synopsis "Assertions for checking the state of R")
    (description
     "This package provides a set of predicates and assertions for checking
the state and capabilities of R, the operating system it is running on, and
the IDE being used.  This is mainly for use by other package developers who
want to include run-time testing features in their own packages.")
    (license license:gpl3+)))

(define-public r-assertive-types
  (package
    (name "r-assertive-types")
    (version "0.0-3")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "assertive.types" version))
       (sha256
        (base32
         "0zxq1jfrzgw95ll7alvm0xnk7aihjdksngq4ya2whyvfjbmv4vdb"))))
    (properties
     `((upstream-name . "assertive.types")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-assertive-base" ,r-assertive-base)
       ("r-assertive-properties" ,r-assertive-properties)
       ("r-codetools" ,r-codetools)))
    (home-page "https://bitbucket.org/richierocks/assertive.types")
    (synopsis "Assertions to check types of variables")
    (description
     "This package provides a set of predicates and assertions for checking
the types of variables.  This is mainly for use by other package developers
who want to include run-time testing features in their own packages.")
    (license license:gpl3+)))

(define-public r-assertive-files
  (package
    (name "r-assertive-files")
    (version "0.0-2")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "assertive.files" version))
       (sha256
        (base32
         "02pfz8j5vwcj5kl6zca46894li7lxwnlrr29j922f14ay6kdssmy"))))
    (properties
     `((upstream-name . "assertive.files")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-assertive-base" ,r-assertive-base)
       ("r-assertive-numbers" ,r-assertive-numbers)))
    (home-page "https://bitbucket.org/richierocks/assertive.files")
    (synopsis "Assertions to check properties of files")
    (description
     "This package provides a set of predicates and assertions for checking
the properties of files and connections.  This is mainly for use by other
package developers who want to include run-time testing features in their own
packages.")
    (license license:gpl3+)))

(define-public r-assertive-code
  (package
    (name "r-assertive-code")
    (version "0.0-3")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "assertive.code" version))
       (sha256
        (base32
         "1qhbp668zfvhqs8avkhg9amp4zyazz6dsy4fc6kpdmw3sv8yi07g"))))
    (properties
     `((upstream-name . "assertive.code")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-assertive-base" ,r-assertive-base)
       ("r-assertive-properties" ,r-assertive-properties)
       ("r-assertive-types" ,r-assertive-types)))
    (home-page "https://bitbucket.org/richierocks/assertive.code")
    (synopsis "Assertions to check properties of code")
    (description
     "This package provides a set of predicates and assertions for checking
the properties of code.  This is mainly for use by other package developers
who want to include run-time testing features in their own packages.")
    (license license:gpl3+)))

(define-public r-assertive-datetimes
  (package
    (name "r-assertive-datetimes")
    (version "0.0-2")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "assertive.datetimes" version))
       (sha256
        (base32
         "00a98fx8p3pr3ckayh8wmxmm4rz01s67wah9697m92yci6pv3m78"))))
    (properties
     `((upstream-name . "assertive.datetimes")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-assertive-base" ,r-assertive-base)
       ("r-assertive-types" ,r-assertive-types)))
    (home-page "https://bitbucket.org/richierocks/assertive.datetimes")
    (synopsis "Assertions to check properties of dates and times")
    (description
     "This package provides a set of predicates and assertions for checking
the properties of dates and times.  This is mainly for use by other package
developers who want to include run-time testing features in their own
packages.")
    (license license:gpl3+)))

(define-public r-assertive-strings
  (package
    (name "r-assertive-strings")
    (version "0.0-3")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "assertive.strings" version))
       (sha256
        (base32
         "0n6jrk88670g4ym0r8ii40a08a90z1xadj8wcryk8h0nl04dchfm"))))
    (properties
     `((upstream-name . "assertive.strings")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-assertive-base" ,r-assertive-base)
       ("r-assertive-types" ,r-assertive-types)
       ("r-stringi" ,r-stringi)))
    (home-page "https://bitbucket.org/richierocks/assertive.strings")
    (synopsis "Assertions to check properties of strings")
    (description
     "This package provides a set of predicates and assertions for checking
the properties of strings.  This is mainly for use by other package developers
who want to include run-time testing features in their own packages.")
    (license license:gpl3+)))

(define-public r-assertive-data-us
  (package
    (name "r-assertive-data-us")
    (version "0.0-2")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "assertive.data.us" version))
       (sha256
        (base32
         "1bgspn0sccmp9z7s7djvdvprgxlyc5vrxznp4zfjb79kwvgn83hq"))))
    (properties
     `((upstream-name . "assertive.data.us")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-assertive-base" ,r-assertive-base)
       ("r-assertive-strings" ,r-assertive-strings)))
    (home-page "https://bitbucket.org/richierocks/assertive.data.us")
    (synopsis "Assertions to check properties of strings")
    (description
     "This package provides a set of predicates and assertions for checking
the properties of US-specific complex data types.  This is mainly for use by
other package developers who want to include run-time testing features in
their own packages.")
    (license license:gpl3+)))

(define-public r-assertive-data-uk
  (package
    (name "r-assertive-data-uk")
    (version "0.0-2")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "assertive.data.uk" version))
       (sha256
        (base32
         "1fzjvhwp7mwkqqix29khvs6zcrc82n6j4czvzzb473vyjyvdlj5b"))))
    (properties
     `((upstream-name . "assertive.data.uk")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-assertive-base" ,r-assertive-base)
       ("r-assertive-strings" ,r-assertive-strings)))
    (home-page "https://bitbucket.org/richierocks/assertive.data.uk")
    (synopsis "Assertions to check properties of strings")
    (description
     "This package provides a set of predicates and assertions for checking
the properties of UK-specific complex data types.  This is mainly for use by
other package developers who want to include run-time testing features in
their own packages.")
    (license license:gpl3+)))

(define-public r-assertive-data
  (package
    (name "r-assertive-data")
    (version "0.0-3")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "assertive.data" version))
       (sha256
        (base32
         "00cvg2g36mdl8plrzx40m63qd55742mddqrchwy9n3c7mm4gn02s"))))
    (properties
     `((upstream-name . "assertive.data")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-assertive-base" ,r-assertive-base)
       ("r-assertive-strings" ,r-assertive-strings)))
    (home-page "https://bitbucket.org/richierocks/assertive.data")
    (synopsis "Assertions to check properties of data")
    (description
     "This package provides a set of predicates and assertions for checking
the properties of (country independent) complex data types.  This is mainly
for use by other package developers who want to include run-time testing
features in their own packages.")
    (license license:gpl3+)))

(define-public r-assertive
  (package
    (name "r-assertive")
    (version "0.3-5")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "assertive" version))
       (sha256
        (base32
         "0blbbhlxcb5ffdxqxi62xs33ljiawh6s22a0pyvbbh79jf46rzr3"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-assertive-base" ,r-assertive-base)
       ("r-assertive-code" ,r-assertive-code)
       ("r-assertive-data" ,r-assertive-data)
       ("r-assertive-data-uk" ,r-assertive-data-uk)
       ("r-assertive-data-us" ,r-assertive-data-us)
       ("r-assertive-datetimes" ,r-assertive-datetimes)
       ("r-assertive-files" ,r-assertive-files)
       ("r-assertive-matrices" ,r-assertive-matrices)
       ("r-assertive-models" ,r-assertive-models)
       ("r-assertive-numbers" ,r-assertive-numbers)
       ("r-assertive-properties" ,r-assertive-properties)
       ("r-assertive-reflection" ,r-assertive-reflection)
       ("r-assertive-sets" ,r-assertive-sets)
       ("r-assertive-strings" ,r-assertive-strings)
       ("r-assertive-types" ,r-assertive-types)
       ("r-knitr" ,r-knitr)))
    (home-page "https://bitbucket.org/richierocks/assertive")
    (synopsis "Readable check functions to ensure code integrity")
    (description
     "This package provides lots of predicates (@code{is_*} functions) to
check the state of your variables, and assertions (@code{assert_*} functions)
to throw errors if they aren't in the right form.")
    (license license:gpl3+)))

(define-public r-dotcall64
  (package
    (name "r-dotcall64")
    (version "1.0-0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "dotCall64" version))
       (sha256
        (base32
         "1b8p7m3w0m7bp977c6jz74xkd611cxg11j49yza59k5fp338scb9"))))
    (properties `((upstream-name . "dotCall64")))
    (build-system r-build-system)
    (native-inputs `(("gfortran" ,gfortran)))
    (home-page "https://git.math.uzh.ch/reinhard.furrer/dotCall64")
    (synopsis "Enhanced foreign function interface supporting long vectors")
    (description
     "This package provides @code{.C64()}, an enhanced version of @code{.C()}
and @code{.Fortran()} from the R foreign function interface.  @code{.C64()}
supports long vectors, arguments of type 64-bit integer, and provides a
mechanism to avoid unnecessary copies of read-only and write-only arguments.
This makes it a convenient and fast interface to C/C++ and Fortran code.")
    (license license:gpl2+)))

(define-public r-spam
  (package
    (name "r-spam")
    (version "2.5-1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "spam" version))
       (sha256
        (base32 "0ry0a76cljlmilrzcriiizcidxyhq1i7i9bqhvl1qda81ld8hifi"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-dotcall64" ,r-dotcall64)))
    (native-inputs `(("gfortran" ,gfortran)))
    (home-page "https://www.math.uzh.ch/pages/spam/")
    (synopsis "Sparse matrix algebra")
    (description
     "This package provides a set of functions for sparse matrix algebra.
Differences with other sparse matrix packages are:

@enumerate
@item it only supports (essentially) one sparse matrix format;
@item it is based on transparent and simple structure(s);
@item it is tailored for MCMC calculations within G(M)RF;
@item and it is fast and scalable (with the extension package @code{spam64}).
@end enumerate\n")
    ;; Either of these licenses
    (license (list license:bsd-3 license:lgpl2.0))))

(define-public r-fields
  (package
    (name "r-fields")
    (version "10.3")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "fields" version))
       (sha256
        (base32 "12k97vfjlz5h8vynirnvik1nyj1iw25n8xl7awmx9mpd6wvgy2s9"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-maps" ,r-maps)
       ("r-spam" ,r-spam)))
    (native-inputs
     `(("gfortran" ,gfortran)))
    (home-page "https://www.image.ucar.edu/fields")
    (synopsis "Tools for spatial data")
    (description
     "This is a package for curve, surface and function fitting with an
emphasis on splines, spatial data and spatial statistics.  The major methods
include cubic, and thin plate splines, Kriging, and compactly supported
covariance functions for large data sets.")
    (license license:gpl2+)))

(define-public r-spatialextremes
  (package
    (name "r-spatialextremes")
    (version "2.0-8")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "SpatialExtremes" version))
       (sha256
        (base32
         "0r2byz5xxc46zqnigdax28q7446ibmzmsmi10lmm2hdks3ml6sl3"))))
    (properties
     `((upstream-name . "SpatialExtremes")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-fields" ,r-fields)
       ("r-maps" ,r-maps)))
    (home-page "http://spatialextremes.r-forge.r-project.org/")
    (synopsis "Modelling spatial extremes")
    (description
     "This package provides tools for the statistical modelling of spatial
extremes using max-stable processes, copula or Bayesian hierarchical models.
More precisely, this package allows (conditional) simulations from various
parametric max-stable models, analysis of the extremal spatial dependence, the
fitting of such processes using composite likelihoods or least square (simple
max-stable processes only), model checking and selection and prediction.")
    (license license:gpl2+)))

(define-public r-drc
  (package
    (name "r-drc")
    (version "3.0-1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "drc" version))
       (sha256
        (base32
         "0c8xn8ripzq270hy8d16fcnx02l02alddznd7fqwk3jyi6113h1y"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-car" ,r-car)
       ("r-gtools" ,r-gtools)
       ("r-mass" ,r-mass)
       ("r-multcomp" ,r-multcomp)
       ("r-plotrix" ,r-plotrix)
       ("r-scales" ,r-scales)))
    (home-page "https://cran.r-project.org/web/packages/drc")
    (synopsis "Analysis of dose-response curves")
    (description
     "This package provides a suite of flexible and versatile model fitting
and after-fitting functions for the analysis of dose-response data.")
    (license license:gpl2+)))

(define-public r-rmeta
  (package
    (name "r-rmeta")
    (version "3.0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "rmeta" version))
       (sha256
        (base32
         "0vkbnxp579v8zmcv1isdbzj5swpr6fq17zwparxcvzswjc2x9ydr"))))
    (build-system r-build-system)
    (home-page "https://cran.r-project.org/web/packages/rmeta")
    (synopsis "Tools for meta-analysis")
    (description
     "This package provides functions for simple fixed and random effects
meta-analysis for two-sample comparisons and cumulative meta-analyses.  It
draws standard summary plots, funnel plots, and computes summaries and tests
for association and heterogeneity.")
    (license license:gpl2)))

(define-public r-bootstrap
  (package
    (name "r-bootstrap")
    (version "2019.6")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "bootstrap" version))
       (sha256
        (base32
         "1546jqhhw5h177ii8jkdikyd26rv6gwkav816np1zks4p7zgsljj"))))
    (build-system r-build-system)
    (native-inputs `(("gfortran" ,gfortran)))
    (home-page "https://cran.r-project.org/web/packages/bootstrap")
    (synopsis "Functions for the book \"An Introduction to the Bootstrap\"")
    (description
     "This package provides software and data for the book \"An Introduction
to the Bootstrap\" by B. Efron and R. Tibshirani, 1993, Chapman and Hall.
This package is primarily provided for projects already based on it, and for
support of the book.  New projects should preferentially use the recommended
package \"boot\".")
    (license license:bsd-3)))

(define-public r-survivalroc
  (package
    (name "r-survivalroc")
    (version "1.0.3")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "survivalROC" version))
       (sha256
        (base32
         "0wnd65ff5w679hxa1zrpfrx9qg47q21pjxppsga6m3h4iq1yfj8l"))))
    (properties `((upstream-name . "survivalROC")))
    (build-system r-build-system)
    (home-page "https://cran.r-project.org/web/packages/survivalROC")
    (synopsis "Time-dependent ROC curve estimation from censored survival data")
    (description
     "Compute time-dependent ROC curve from censored survival data using
Kaplan-Meier (KM) or Nearest Neighbor Estimation (NNE) method of Heagerty,
Lumley & Pepe (Biometrics, Vol 56 No 2, 2000, PP 337-344)")
    (license license:gpl2+)))

(define-public r-longitudinal
  (package
    (name "r-longitudinal")
    (version "1.1.12")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "longitudinal" version))
       (sha256
        (base32
         "1d83ws28nxi3kw5lgd5n5y7865djq7ky72fw3ddi1fkkhg1r9y6l"))))
    (build-system r-build-system)
    (propagated-inputs `(("r-corpcor" ,r-corpcor)))
    (home-page "http://strimmerlab.org/software/longitudinal/")
    (synopsis "Analysis of multiple time course data")
    (description
     "This package contains general data structures and functions for
longitudinal data with multiple variables, repeated measurements, and
irregularly spaced time points.  It also implements a shrinkage estimator of
dynamical correlation and dynamical covariance.")
    (license license:gpl3+)))

(define-public r-genenet
  (package
    (name "r-genenet")
    (version "1.2.14")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "GeneNet" version))
       (sha256
        (base32
         "0cdhrj15rz0w0pyw3r8mikrzsdh95y5i1c0pa3cn0c2bjnjx3x3n"))))
    (properties `((upstream-name . "GeneNet")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-corpcor" ,r-corpcor)
       ("r-fdrtool" ,r-fdrtool)
       ("r-longitudinal" ,r-longitudinal)))
    (home-page "http://strimmerlab.org/software/genenet/")
    (synopsis "Modeling and inferring gene networks")
    (description
     "This package analyzes gene expression (time series) data with focus on
the inference of gene networks.  In particular, GeneNet implements the methods
of Schaefer and Strimmer (2005a,b,c) and Opgen-Rhein and Strimmer (2006, 2007)
for learning large-scale gene association networks (including assignment of
putative directions).")
    (license license:gpl3+)))

(define-public r-rbamtools
  (package
    (name "r-rbamtools")
    (version "2.16.17")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "rbamtools" version))
       (sha256
        (base32
         "0qj37ljdva3v29s01dkrbg31mcfzy3bl145cp40d54v4h9xhcghc"))))
    (build-system r-build-system)
    (inputs `(("zlib" ,zlib)))
    (propagated-inputs
     `(("r-refgenome" ,r-refgenome)))
    (home-page "https://cran.r-project.org/web/packages/rbamtools")
    (synopsis "Read and write BAM (binary alignment) files")
    (description
     "This package provides an R interface to functions of the SAMtools
library.")
    (license license:artistic2.0)))

(define-public r-protviz
  (package
    (name "r-protviz")
    (version "0.6.3")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "protViz" version))
       (sha256
        (base32
         "1ldciqh3f43xr9663yyhd9r6qwrg4c4vmkprlcancbnd460wakg7"))))
    (properties `((upstream-name . "protViz")))
    (build-system r-build-system)
    (propagated-inputs `(("r-rcpp" ,r-rcpp)))
    (home-page "https://github.com/protViz/protViz/")
    (synopsis "Visualizing and analyzing mass spectrometry data in proteomics")
    (description
     "This package helps with quality checks, visualizations and analysis of
mass spectrometry data, coming from proteomics experiments.  The package is
developed, tested and used at the Functional Genomics Center Zurich, where it
is used mainly for prototyping, teaching, and having fun with proteomics data.
But it can also be used to do data analysis for small scale data sets.")
    (license license:gpl3)))

(define-public r-cmprsk
  (package
    (name "r-cmprsk")
    (version "2.2-9")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "cmprsk" version))
       (sha256
        (base32 "0xhgfg5b4i9skkaxp7gzkafgg5bqs5q1rp4hpw2jjmykg2nifn99"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-survival" ,r-survival)))
    (native-inputs
     `(("gfortran" ,gfortran)))
    (home-page "https://cran.r-project.org/web/packages/cmprsk")
    (synopsis "Subdistribution analysis of competing risks")
    (description
     "This package provides tool for estimation, testing and regression
modeling of subdistribution functions in competing risks, as described in
Gray (1988), A class of K-sample tests for comparing the cumulative incidence
of a competing risk, Ann. Stat. 16:1141-1154, and Fine JP and Gray RJ (1999),
A proportional hazards model for the subdistribution of a competing risk,
JASA, 94:496-509.")
    (license license:gpl2+)))

(define-public r-etm
  (package
    (name "r-etm")
    (version "1.0.5.1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "etm" version))
       (sha256
        (base32
         "0m41pm277sd50pharigcqzr1a2g92wnmdf6fcab6fx16ia2fzrm7"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-data-table" ,r-data-table)
       ("r-lattice" ,r-lattice)
       ("r-rcpp" ,r-rcpp)
       ("r-rcpparmadillo" ,r-rcpparmadillo)
       ("r-survival" ,r-survival)))
    (home-page "https://cran.r-project.org/web/packages/etm")
    (synopsis "Empirical transition matrix")
    (description
     "The @dfn{empirical transition matrix} (etm) package estimates
the matrix of transition probabilities for any time-inhomogeneous multistate
model with finite state space using the Aalen-Johansen estimator.")
    (license license:expat)))

(define-public r-epi
  (package
    (name "r-epi")
    (version "2.40")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "Epi" version))
       (sha256
        (base32
         "046y10vwks5y84pzccmrn6d4pd6qz70imvp1hw5ywp8fnwzfh4g5"))))
    (properties `((upstream-name . "Epi")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-cmprsk" ,r-cmprsk)
       ("r-data-table" ,r-data-table)
       ("r-etm" ,r-etm)
       ("r-mass" ,r-mass)
       ("r-matrix" ,r-matrix)
       ("r-mgcv" ,r-mgcv)
       ("r-numderiv" ,r-numderiv)
       ("r-plyr" ,r-plyr)
       ("r-survival" ,r-survival)
       ("r-zoo" ,r-zoo)))
    (home-page "https://BendixCarstensen.com/Epi/")
    (synopsis "Statistical analysis in epidemiology")
    (description
     "This package provides functions for demographic and epidemiological
analysis in the Lexis diagram, i.e. register and cohort follow-up data, in
particular representation, manipulation and simulation of multistate data -
the Lexis suite of functions, which includes interfaces to the @code{mstate},
@code{etm} and @code{cmprsk} packages.  It also contains functions for
Age-Period-Cohort and Lee-Carter modeling and a function for interval censored
data and some useful functions for tabulation and plotting, as well as a
number of epidemiological data sets.")
    (license license:gpl2)))

(define-public r-ppls
  (package
    (name "r-ppls")
    (version "1.6-1.1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "ppls" version))
       (sha256
        (base32
         "1zyrisy3c4cz896j1bjh61sf57wdl9p8ywdq268cl819szfq78mx"))))
    (build-system r-build-system)
    (propagated-inputs `(("r-mass" ,r-mass)))
    (home-page "https://cran.r-project.org/web/packages/ppls")
    (synopsis "Penalized partial least squares")
    (description
     "This package contains linear and nonlinear regression methods based on
partial least squares and penalization techniques.  Model parameters are
selected via cross-validation, and confidence intervals ans tests for the
regression coefficients can be conducted via jackknifing.")
    (license license:gpl2+)))

(define-public r-huge
  (package
    (name "r-huge")
    (version "1.3.4.1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "huge" version))
       (sha256
        (base32 "11m80dnaxqw5v006q6kvhndl2y5ih5553fcqg4jcaljd8sp9xvvq"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-igraph" ,r-igraph)
       ("r-mass" ,r-mass)
       ("r-matrix" ,r-matrix)
       ("r-rcpp" ,r-rcpp)
       ("r-rcppeigen" ,r-rcppeigen)))
    (home-page "https://cran.r-project.org/web/packages/huge")
    (synopsis "High-dimensional undirected graph estimation")
    (description
     "This package provides a general framework for high-dimensional
undirected graph estimation.  It integrates data preprocessing, neighborhood
screening, graph estimation, and model selection techniques into a pipeline.")
    (license license:gpl2)))

(define-public r-parcor
  (package
    (name "r-parcor")
    (version "0.2-6")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "parcor" version))
       (sha256
        (base32
         "0vgs6k92vdr0cmb8cwbv2ff6qavw30agskfd8bfh17hsskrisvx0"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-epi" ,r-epi)
       ("r-genenet" ,r-genenet)
       ("r-glmnet" ,r-glmnet)
       ("r-mass" ,r-mass)
       ("r-ppls" ,r-ppls)))
    (home-page "https://cran.r-project.org/web/packages/parcor")
    (synopsis "Regularized estimation of partial correlation matrices")
    (description
     "This package estimates the matrix of partial correlations based on
different regularized regression methods: lasso, adaptive lasso, PLS, and
Ridge Regression.  In addition, the package provides model selection for
lasso, adaptive lasso and Ridge regression based on cross-validation.")
    (license license:gpl2+)))

(define-public r-mcmc
  (package
    (name "r-mcmc")
    (version "0.9-7")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "mcmc" version))
       (sha256
        (base32
         "0q42m8ab7b6bxhns494ksjdss5f3c5m2jjfdlfj6fk1nz7ax7i5p"))))
    (build-system r-build-system)
    (home-page "https://www.stat.umn.edu/geyer/mcmc/")
    (synopsis "Markov chain Monte Carlo")
    (description
     "This package simulates continuous distributions of random vectors using
@dfn{Markov chain Monte Carlo} (MCMC).  Users specify the distribution by an R
function that evaluates the log unnormalized density.  Algorithms are random
walk Metropolis algorithm (function @code{metrop}), simulated
tempering (function @code{temper}), and morphometric random walk
Metropolis (function @code{morph.metrop}), which achieves geometric ergodicity
by change of variable.")
    (license license:expat)))

(define-public r-listenv
  (package
    (name "r-listenv")
    (version "0.8.0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "listenv" version))
       (sha256
        (base32
         "0ps8bk7zlhbviawrw7vw25skjq81hkk3ijyi6g74dmfqy8zsyapx"))))
    (build-system r-build-system)
    (native-inputs
     `(("r-r-rsp" ,r-r-rsp))) ; vignette builder
    (home-page "https://github.com/HenrikBengtsson/listenv")
    (synopsis "Environments behaving (almost) as lists")
    (description
     "This package implements list environments.  List environments are
environments that have list-like properties.  For instance, the elements of a
list environment are ordered and can be accessed and iterated over using index
subsetting.")
    (license license:lgpl2.1+)))

(define-public r-globals
  (package
    (name "r-globals")
    (version "0.12.5")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "globals" version))
       (sha256
        (base32
         "1ha8iasgijp4q3v2b0b17y1wh7cd3nvzd9b03w49qm2bidkaf68m"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-codetools" ,r-codetools)))
    (home-page "https://github.com/HenrikBengtsson/globals")
    (synopsis "Identify global objects in R expressions")
    (description
     "This package provides tools to identify global (\"unknown\" or \"free\")
objects in R expressions by code inspection using various strategies, e.g.
conservative or liberal.  The objective of this package is to make it as
simple as possible to identify global objects for the purpose of exporting
them in distributed compute environments.")
    (license license:lgpl2.1+)))

(define-public r-future
  (package
    (name "r-future")
    (version "1.16.0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "future" version))
       (sha256
        (base32
         "1xaqh0b2knf5bp23mc0kriq0iqhqna31q3b7d960piqjhzrb03dm"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-digest" ,r-digest)
       ("r-globals" ,r-globals)
       ("r-listenv" ,r-listenv)))
    (native-inputs
     `(("r-r-rsp" ,r-r-rsp))) ; vignette builder
    (home-page "https://github.com/HenrikBengtsson/future")
    (synopsis "Unified parallel and distributed processing in R")
    (description
     "The purpose of this package is to provide a lightweight and unified
Future API for sequential and parallel processing of R expression via futures.
This package implements sequential, multicore, multisession, and cluster
futures.  With these, R expressions can be evaluated on the local machine, in
parallel a set of local machines, or distributed on a mix of local and remote
machines.  Extensions to this package implement additional backends for
processing futures via compute cluster schedulers etc.  Because of its unified
API, there is no need to modify any code in order to switch from sequential on
the local machine to, say, distributed processing on a remote compute cluster.")
    (license license:lgpl2.1+)))

(define-public r-future-apply
  (package
    (name "r-future-apply")
    (version "1.4.0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "future.apply" version))
       (sha256
        (base32
         "1kgq6dv96hdy35kysqkn606nj7s9dp4ibgpm6n46gqhc5n75lzkk"))))
    (properties `((upstream-name . "future.apply")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-future" ,r-future)
       ("r-globals" ,r-globals)))
    (native-inputs
     `(("r-r-rsp" ,r-r-rsp))) ; vignette builder
    (home-page "https://github.com/HenrikBengtsson/future.apply")
    (synopsis "Apply function to elements in parallel using futures")
    (description
     "This package provides implementations of @code{apply()},
@code{eapply()}, @code{lapply()}, @code{Map()}, @code{mapply()},
@code{replicate()}, @code{sapply()}, @code{tapply()}, and @code{vapply()} that
can be resolved using any future-supported backend, e.g. parallel on the local
machine or distributed on a compute cluster.")
    (license license:gpl2+)))

(define-public r-rsvd
  (package
    (name "r-rsvd")
    (version "1.0.3")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "rsvd" version))
       (sha256
        (base32
         "1fvrw46fl5xb2akaa4mp8nja4h7nn4bdhnjdrk22fsdfqc7hwmhk"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-matrix" ,r-matrix)))
    (home-page "https://github.com/erichson/rSVD")
    (synopsis "Randomized singular value decomposition")
    (description
     "Low-rank matrix decompositions are fundamental tools and widely used for
data analysis, dimension reduction, and data compression.  Classically, highly
accurate deterministic matrix algorithms are used for this task.  However, the
emergence of large-scale data has severely challenged our computational
ability to analyze big data.  The concept of randomness has been demonstrated
as an effective strategy to quickly produce approximate answers to familiar
problems such as the @dfn{singular value decomposition} (SVD).  This package
provides several randomized matrix algorithms such as the randomized singular
value decomposition (@code{rsvd}), randomized principal component
analysis (@code{rpca}), randomized robust principal component
analysis (@code{rrpca}), randomized interpolative decomposition (@code{rid}),
and the randomized CUR decomposition (@code{rcur}).  In addition several plot
functions are provided.")
    (license license:gpl3+)))

(define-public r-sloop
  (package
    (name "r-sloop")
    (version "1.0.1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "sloop" version))
       (sha256
        (base32
         "00fk5fr5zsk2qxc1kfhmshhjxgnamm3401089sx8m2l529zd6r8j"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-codetools" ,r-codetools)
       ("r-crayon" ,r-crayon)
       ("r-purrr" ,r-purrr)
       ("r-rlang" ,r-rlang)
       ("r-tibble" ,r-tibble)))
    (home-page "https://github.com/r-lib/sloop")
    (synopsis "Helpers for object-oriented programming in R")
    (description
     "This package provides a collection of helper functions designed to
help you to better understand object oriented programming in R, particularly
using @code{S3}.")
    (license license:gpl3)))

(define-public r-capushe
  (package
    (name "r-capushe")
    (version "1.1.1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "capushe" version))
       (sha256
        (base32
         "1aa76ir1kp67hiz7dr60azyc71yzslshyc640fjh0fpw0sp5kwbc"))))
    (build-system r-build-system)
    (propagated-inputs `(("r-mass" ,r-mass)))
    (home-page "https://cran.r-project.org/web/packages/capushe/index.html")
    (synopsis "Calibrating penalties using slope heuristics")
    (description
     "This package provides tools for the calibration of penalized criteria
for model selection.  The calibration methods available are based on the slope
heuristics.")
    (license license:gpl2+)))

(define-public r-dorng
  (package
    (name "r-dorng")
    (version "1.8.2")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "doRNG" version))
       (sha256
        (base32
         "1jff27zzrvd1fd61x2m9468h8xn3s1c9f6wibviy5zdhj5dx9s9k"))))
    (properties `((upstream-name . "doRNG")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-foreach" ,r-foreach)
       ("r-iterators" ,r-iterators)
       ("r-rngtools" ,r-rngtools)))
    (home-page "https://renozao.github.io/doRNG/")
    (synopsis "Generic reproducible parallel backend for foreach loops")
    (description
     "This package provides functions to perform reproducible parallel
@code{foreach} loops, using independent random streams as generated by
L'Ecuyer's combined multiple-recursive generator.  It enables to easily
convert standard @code{%dopar%} loops into fully reproducible loops,
independently of the number of workers, the task scheduling strategy, or the
chosen parallel environment and associated foreach backend.")
    (license license:gpl2+)))

(define-public r-blockmodeling
  (package
    (name "r-blockmodeling")
    (version "0.3.6")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "blockmodeling" version))
       (sha256
        (base32
         "12paf76l3wlxad14bkxn37lw9rg6ka473m86wlcf3yhriw8kbaiz"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-matrix" ,r-matrix)))
    (native-inputs `(("gfortran" ,gfortran)))
    (home-page "https://cran.r-project.org/web/packages/blockmodeling")
    (synopsis "Generalized and classical blockmodeling of valued networks")
    (description
     "This package is primarily meant as an implementation of generalized
blockmodeling for valued networks.  In addition, measures of similarity or
dissimilarity based on structural equivalence and regular equivalence (REGE
algorithms) can be computed and partitioned matrices can be plotted.")
    (license license:gpl2+)))

(define-public r-upsetr
  (package
    (name "r-upsetr")
    (version "1.4.0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "UpSetR" version))
       (sha256
        (base32
         "007i0njnjjy7vbrxabwav7a1kk2n0hn2mkvqsdzzfk10ckp5y7im"))))
    (properties `((upstream-name . "UpSetR")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-ggplot2" ,r-ggplot2)
       ("r-gridextra" ,r-gridextra)
       ("r-plyr" ,r-plyr)
       ("r-scales" ,r-scales)))
    (home-page "https://github.com/hms-dbmi/UpSetR")
    (synopsis "Visualize intersecting sets")
    (description
     "This package provides a more scalable alternative to Venn and Euler
diagrams for visualizing intersecting sets.  Create visualizations of
intersecting sets using a novel matrix design, along with visualizations of
several common set, element and attribute related tasks.")
    (license license:expat)))

;; This package includes a JavaScript file, which is not minified.  When
;; upgrading please check that there are no new minified JavaScript files.
(define-public r-shinybs
  (package
    (name "r-shinybs")
    (version "0.61")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "shinyBS" version))
       (sha256
        (base32
         "0rhim4mbp4x9vvm7xkmpl7mhb9qd1gr96cr4dv330v863ra2kgji"))))
    (properties `((upstream-name . "shinyBS")))
    (build-system r-build-system)
    ;; The tests spawn Shiny browser apps.  They cannot be run
    ;; non-interactively.
    (arguments '(#:tests? #f))
    (propagated-inputs
     `(("r-htmltools" ,r-htmltools)
       ("r-shiny" ,r-shiny)))
    (home-page "https://ebailey78.github.io/shinyBS/")
    (synopsis "Twitter Bootstrap components for Shiny")
    (description
     "This package adds additional Twitter Bootstrap components to Shiny.")
    (license license:gpl3)))

(define-public r-outliers
  (package
    (name "r-outliers")
    (version "0.14")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "outliers" version))
       (sha256
        (base32
         "0vcqfqmmv4yblyp3s6bd25r49pxb7hjzipiic5a82924nqfqzkmn"))))
    (build-system r-build-system)
    (home-page "https://cran.r-project.org/web/packages/outliers/index.html")
    (synopsis "Tests for outliers")
    (description
     "This package provides a collection of some tests commonly used for
identifying outliers.")
    (license license:gpl2+)))

(define-public r-bayesm
  (package
    (name "r-bayesm")
    (version "3.1-4")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "bayesm" version))
       (sha256
        (base32 "154glks7rsjkza0sfi1kj7wj727py9sl1ba6sswflwmwc9n226q6"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-rcpp" ,r-rcpp)
       ("r-rcpparmadillo" ,r-rcpparmadillo)))
    (home-page "http://www.perossi.org/home/bsm-1")
    (synopsis "Bayesian inference for marketing/micro-econometrics")
    (description
     "This package covers many important models used in marketing and
micro-econometrics applications, including Bayes Regression (univariate or
multivariate dep var), Bayes Seemingly Unrelated Regression (SUR), Binary and
Ordinal Probit, Multinomial Logit (MNL) and Multinomial Probit (MNP),
Multivariate Probit, Negative Binomial (Poisson) Regression, Multivariate
Mixtures of Normals (including clustering), Dirichlet Process Prior Density
Estimation with normal base, Hierarchical Linear Models with normal prior and
covariates, Hierarchical Linear Models with a mixture of normals prior and
covariates, Hierarchical Multinomial Logits with a mixture of normals prior
and covariates, Hierarchical Multinomial Logits with a Dirichlet Process prior
and covariates, Hierarchical Negative Binomial Regression Models, Bayesian
analysis of choice-based conjoint data, Bayesian treatment of linear
instrumental variables models, Analysis of Multivariate Ordinal survey data
with scale usage heterogeneity, and Bayesian Analysis of Aggregate Random
Coefficient Logit Models.")
    (license license:gpl2+)))

(define-public r-tensora
  (package
    (name "r-tensora")
    (version "0.36.1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "tensorA" version))
       (sha256
        (base32
         "176hjy3bvg3in62r97wxbhq187sjz6c1gwy9x6spaxl6k4my3zy7"))))
    (properties `((upstream-name . "tensorA")))
    (build-system r-build-system)
    (home-page "http://www.stat.boogaart.de/tensorA")
    (synopsis "Advanced tensor arithmetic with named indices")
    (description
     "This package provides convenience functions for advanced linear algebra
with tensors and computation with datasets of tensors on a higher level
abstraction.  It includes Einstein and Riemann summing conventions, dragging,
co- and contravariate indices, and parallel computations on sequences of
tensors.")
    (license license:gpl2+)))

(define-public r-rarpack
  (package
    (name "r-rarpack")
    (version "0.11-0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "rARPACK" version))
       (sha256
        (base32
         "12h2y46xcfldhjdmm960swgn9b23zvkj5vg2bi42s9qxwgi02d63"))))
    (properties `((upstream-name . "rARPACK")))
    (build-system r-build-system)
    (propagated-inputs `(("r-rspectra" ,r-rspectra)))
    (home-page "https://github.com/yixuan/rARPACK")
    (synopsis "Solvers for large scale eigenvalue and SVD problems")
    (description
     "This package was previously an R wrapper of the ARPACK library, and now
a shell of the R package RSpectra, an R interface to the Spectra library for
solving large scale eigenvalue/vector problems.  The current version of
rARPACK simply imports and exports the functions provided by RSpectra.  New
users of rARPACK are advised to switch to the RSpectra package.")
    (license license:bsd-3)))

(define-public r-compositions
  (package
    (name "r-compositions")
    (version "1.40-4")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "compositions" version))
       (sha256
        (base32
         "0z40llyij3cc80ac1vzzrpykk6ysp89bn6dyyh40fbnc4anwx69a"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-bayesm" ,r-bayesm)
       ("r-robustbase" ,r-robustbase)
       ("r-tensora" ,r-tensora)))
    (home-page "http://www.stat.boogaart.de/compositions")
    (synopsis "Compositional data analysis")
    (description
     "This package provides functions for the consistent analysis of
compositional data (e.g. portions of substances) and positive
numbers (e.g. concentrations).")
    (license license:gpl2+)))

(define-public r-cobs
  (package
    (name "r-cobs")
    (version "1.3-4")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "cobs" version))
       (sha256
        (base32
         "0hiw5smk6kgk0gb9840kcqkhkybl7n30s77xhjc395x09izbgix1"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-quantreg" ,r-quantreg)
       ("r-sparsem" ,r-sparsem)))
    (home-page "https://cran.r-project.org/web/packages/cobs")
    (synopsis "Constrained B-Splines (sparse matrix based)")
    (description
     "This package provides qualitatively constrained (regression) smoothing
splines via linear programming and sparse matrices.")
    (license license:gpl2+)))

(define-public r-drimpute
  (package
    (name "r-drimpute")
    (version "1.0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "DrImpute" version))
       (sha256
        (base32
         "1adzarrwqb282pqgx2yqswp9rpwd1naxsmar54kddr6qyd6b923b"))))
    (properties `((upstream-name . "DrImpute")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-rcpp" ,r-rcpp)
       ("r-rcpparmadillo" ,r-rcpparmadillo)))
    (home-page "https://github.com/ikwak2/DrImpute")
    (synopsis "Imputing dropout events in single-cell RNA-Seq data")
    (description
     "This is an R package for imputing dropout events.  Many statistical
methods in cell type identification, visualization and lineage reconstruction
do not account for dropout events.  DrImpute can improve the performance of
such software by imputing dropout events.")
    (license license:gpl3)))

(define-public r-gamlss-dist
  (package
    (name "r-gamlss-dist")
    (version "5.1-6")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "gamlss.dist" version))
       (sha256
        (base32 "1p904x0b07z4amaqdn2xhs7qzbq8lisr6lqc844s3pkxzmny7w1z"))))
    (properties `((upstream-name . "gamlss.dist")))
    (build-system r-build-system)
    (propagated-inputs `(("r-mass" ,r-mass)))
    (home-page "http://www.gamlss.org/")
    (synopsis "Distributions for Generalized Additive Models for location scale and shape")
    (description
     "This package provides a set of distributions which can be used for
modelling the response variables in Generalized Additive Models for Location
Scale and Shape.  The distributions can be continuous, discrete or mixed
distributions.  Extra distributions can be created, by transforming, any
continuous distribution defined on the real line, to a distribution defined on
ranges 0 to infinity or 0 to 1, by using a @code{log} or a @code{logit}
transformation, respectively.")
    ;; Either version of the GPL.
    (license (list license:gpl2 license:gpl3))))

;; This package includes JavaScript files, which are not minified.  When
;; upgrading please check that there are no new minified JavaScript files.
(define-public r-shinyjs
  (package
    (name "r-shinyjs")
    (version "1.1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "shinyjs" version))
       (sha256
        (base32
         "14k8y313ppj23m9rhlk8jc94x6sbn3qrsnx6xrijiyv8m8dii1l9"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-digest" ,r-digest)
       ("r-htmltools" ,r-htmltools)
       ("r-jsonlite" ,r-jsonlite)
       ("r-shiny" ,r-shiny)))
    (home-page "https://deanattali.com/shinyjs")
    (synopsis "Improve the user experience of your Shiny apps")
    (description
     "Perform common useful JavaScript operations in Shiny apps that will
greatly improve your apps without having to know any JavaScript.  Examples
include: hiding an element, disabling an input, resetting an input back to its
original value, delaying code execution by a few seconds, and many more useful
functions for both the end user and the developer.  Shinyjs can also be used
to easily call your own custom JavaScript functions from R.")
    (license license:agpl3+)))

;; This package includes minified JavaScript files.  When upgrading please
;; check that there are no new minified JavaScript files.
(define-public r-colourpicker
  (package
    (name "r-colourpicker")
    (version "1.0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "colourpicker" version))
       (sha256
        (base32
         "0z3v2083g7kwdp21x9s2n1crfh24agpdq3yxkcdzc2awn2pwpnpi"))))
    (build-system r-build-system)
    (arguments
     `(#:modules ((guix build utils)
                  (guix build r-build-system)
                  (srfi srfi-1)
                  (ice-9 popen))
       #:phases
       (modify-phases %standard-phases
         (add-after 'unpack 'process-javascript
           (lambda* (#:key inputs #:allow-other-keys)
             (with-directory-excursion "inst"
               (call-with-values
                   (lambda ()
                     (unzip2
                      `((,(assoc-ref inputs "js-salvattore")
                         "examples/colourInput/www/salvattore.min.js")
                        (,(assoc-ref inputs "js-jquery")
                         "htmlwidgets/lib/jquery/jquery.min.js")
                        ("www/shared/colourpicker/js/colourpicker.js"
                         "www/shared/colourpicker/js/colourpicker.min.js"))))
                 (lambda (sources targets)
                   (for-each (lambda (source target)
                               (format #t "Processing ~a --> ~a~%"
                                       source target)
                               (delete-file target)
                               (let ((minified (open-pipe* OPEN_READ "uglify-js" source)))
                                 (call-with-output-file target
                                   (lambda (port)
                                     (dump-port minified port)))))
                             sources targets))))
             #t)))))
    (propagated-inputs
     `(("r-ggplot2" ,r-ggplot2)
       ("r-htmltools" ,r-htmltools)
       ("r-htmlwidgets" ,r-htmlwidgets)
       ("r-jsonlite" ,r-jsonlite)
       ("r-miniui" ,r-miniui)
       ("r-shiny" ,r-shiny)
       ("r-shinyjs" ,r-shinyjs)))
    (native-inputs
     `(("uglify-js" ,uglify-js)
       ("js-jquery"
        ,(origin
           (method url-fetch)
           (uri "https://code.jquery.com/jquery-3.3.1.js")
           (sha256
            (base32
             "1b8zxrp6xwzpw25apn8j4qws0f6sr7qr7h2va5h1mjyfqvn29anq"))))
       ("js-salvattore"
        ,(origin
           (method url-fetch)
           (uri "https://raw.githubusercontent.com/rnmp/salvattore/v1.0.9/dist/salvattore.js")
           (sha256
            (base32
             "0lfrbx7l9w5x89jpc6njmd0pk7h8fpvg537vklai2vf7b1r2nnk5"))))))
    (home-page "https://github.com/daattali/colourpicker")
    (synopsis "Color picker tool for Shiny and for selecting colors in plots")
    (description
     "This package provides a color picker that can be used as an input in
Shiny apps or Rmarkdown documents.  The color picker supports alpha opacity,
custom color palettes, and many more options.  A plot color helper tool is
available as an RStudio Addin, which helps you pick colors to use in your
plots.  A more generic color picker RStudio Addin is also provided to let you
select colors to use in your R code.")
    (license license:expat)))

(define-public r-ggextra
  (package
    (name "r-ggextra")
    (version "0.9")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "ggExtra" version))
       (sha256
        (base32
         "18mbi6gblqmrsciad1d2c9ngllk6mayaqj43k40hjq9ydqnvjbgj"))))
    (properties `((upstream-name . "ggExtra")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-colourpicker" ,r-colourpicker)
       ("r-ggplot2" ,r-ggplot2)
       ("r-gtable" ,r-gtable)
       ("r-miniui" ,r-miniui)
       ("r-r6" ,r-r6)
       ("r-scales" ,r-scales)
       ("r-shiny" ,r-shiny)
       ("r-shinyjs" ,r-shinyjs)))
    (home-page "https://github.com/daattali/ggExtra")
    (synopsis "Marginal histograms for ggplot2 and other enhancements")
    (description
     "This package is a collection of functions and layers to enhance ggplot2.
The flagship function is @code{ggMarginal()}, which can be used to add
marginal histograms/boxplots/density plots to ggplot2 scatterplots.")
    (license license:expat)))

(define-public r-minpack-lm
  (package
    (name "r-minpack-lm")
    (version "1.2-1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "minpack.lm" version))
       (sha256
        (base32
         "18ym2pdql5vzngc7q5gn66d153hrfrnd8ilv8yh6vd7j7sx7vjql"))))
    (properties `((upstream-name . "minpack.lm")))
    (build-system r-build-system)
    (native-inputs `(("gfortran" ,gfortran)))
    (home-page "https://cran.r-project.org/web/packages/minpack.lm")
    (synopsis "Levenberg-Marquardt Nonlinear Least-Squares algorithm")
    (description
     "The @code{nls.lm} function provides an R interface to @code{lmder} and
@code{lmdif} from the MINPACK library, for solving nonlinear least-squares
problems by a modification of the Levenberg-Marquardt algorithm, with support
for lower and upper parameter bounds.  The implementation can be used via
@code{nls}-like calls using the @code{nlsLM} function.")
    (license license:gpl3)))

(define-public r-moments
  (package
    (name "r-moments")
    (version "0.14")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "moments" version))
       (sha256
        (base32
         "0f9y58w1hxcz4bqivirx25ywlmc80gbi6dfx5cnhkpdg1pk82fra"))))
    (build-system r-build-system)
    (home-page "https://cran.r-project.org/web/packages/moments")
    (synopsis "Moments, cumulants, skewness, kurtosis and related tests")
    (description
     "This package provides functions to calculate: moments, Pearson's
kurtosis, Geary's kurtosis and skewness; it also includes tests related to
them (Anscombe-Glynn, D'Agostino, Bonett-Seier).")
    (license license:gpl2+)))

(define-public r-msir
  (package
    (name "r-msir")
    (version "1.3.2")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "msir" version))
       (sha256
        (base32
         "0pvc3q162vqq3k39nni732x05zzfz4y9y2zf56d83185ypszv9kb"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-mclust" ,r-mclust)))
    (home-page "https://cran.r-project.org/web/packages/msir")
    (synopsis "Model-based sliced inverse regression")
    (description
     "This is an R package for dimension reduction based on finite Gaussian
mixture modeling of inverse regression.")
    (license license:gpl2+)))

(define-public r-pbivnorm
  (package
    (name "r-pbivnorm")
    (version "0.6.0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "pbivnorm" version))
       (sha256
        (base32
         "05jzrjqxzbcf6z245hlk7sjxiszv9paadaaimvcx5y5qgi87vhq7"))))
    (build-system r-build-system)
    (native-inputs `(("gfortran" ,gfortran)))
    (home-page "https://github.com/brentonk/pbivnorm")
    (synopsis "Vectorized bivariate normal CDF")
    (description
     "This package provides a vectorized R function for calculating
probabilities from a standard bivariate normal CDF.")
    (license license:gpl2+)))

(define-public r-lavaan
  (package
    (name "r-lavaan")
    (version "0.6-5")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "lavaan" version))
       (sha256
        (base32
         "04kvsh2m6mnzlhv83phr3hjzy4sx1ck6f7dgsm7xb8cs84dnxszy"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-mass" ,r-mass)
       ("r-mnormt" ,r-mnormt)
       ("r-numderiv" ,r-numderiv)
       ("r-pbivnorm" ,r-pbivnorm)))
    (home-page "http://lavaan.ugent.be")
    (synopsis "Latent variable analysis")
    (description
     "This package provides tools to fit a variety of latent variable models,
including confirmatory factor analysis, structural equation modeling and
latent growth curve models.")
    (license license:gpl2+)))

(define-public r-nonnest2
  (package
    (name "r-nonnest2")
    (version "0.5-3")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "nonnest2" version))
       (sha256
        (base32
         "1mnv4pa583ir9s03h952hk40lwdywr3g88g76sk1zsa54rcmn82c"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-compquadform" ,r-compquadform)
       ("r-lavaan" ,r-lavaan)
       ("r-mvtnorm" ,r-mvtnorm)
       ("r-sandwich" ,r-sandwich)))
    (native-inputs
     `(("r-knitr" ,r-knitr)))
    (home-page "https://cran.r-project.org/web/packages/nonnest2/")
    (synopsis "Tests of non-nested models")
    (description
     "This package allows for testing of non-nested models.  It includes tests
of model distinguishability and of model fit that can be applied to both
nested and non-nested models.  The package also includes functionality to
obtain confidence intervals associated with AIC and BIC.")
    ;; Either version of the GPL.
    (license (list license:gpl2 license:gpl3))))

(define-public r-penalized
  (package
    (name "r-penalized")
    (version "0.9-51")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "penalized" version))
       (sha256
        (base32
         "1zcrwa93mc27qj3g4ayc2k895r6g8q0g6qb2azmvj7wqk750va7a"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-rcpp" ,r-rcpp)
       ("r-rcpparmadillo" ,r-rcpparmadillo)
       ("r-survival" ,r-survival)))
    (home-page "https://cran.r-project.org/web/packages/penalized/")
    (synopsis "Penalized estimation in GLMs and in the Cox model")
    (description
     "This package provides tools for fitting possibly high dimensional
penalized regression models.  The penalty structure can be any combination of
an L1 penalty (lasso and fused lasso), an L2 penalty (ridge) and a positivity
constraint on the regression coefficients.  The supported regression models
are linear, logistic and Poisson regression and the Cox Proportional Hazards
model.  Cross-validation routines allow optimization of the tuning
parameters.")
    (license license:gpl2+)))

(define-public r-zim
  (package
    (name "r-zim")
    (version "1.1.0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "ZIM" version))
       (sha256
        (base32
         "0scyfjn4ilsvha3x41c3b8bcfi31hlhwm77wn2a8hj5dsvnnmzig"))))
    (properties `((upstream-name . "ZIM")))
    (build-system r-build-system)
    (propagated-inputs `(("r-mass" ,r-mass)))
    (home-page "https://github.com/biostatstudio/ZIM")
    (synopsis "Zero-inflated models (ZIM) for count time series with excess zeros")
    (description
     "Analyze count time series with excess zeros.  Two types of statistical
models are supported: Markov regression and state-space models.  They are also
known as observation-driven and parameter-driven models respectively in the
time series literature.  The functions used for Markov regression or
observation-driven models can also be used to fit ordinary regression models
with independent data under the zero-inflated Poisson (ZIP) or zero-inflated
negative binomial (ZINB) assumption.  The package also contains miscellaneous
functions to compute density, distribution, quantile, and generate random
numbers from ZIP and ZINB distributions.")
    (license license:gpl3)))

(define-public r-nor1mix
  (package
    (name "r-nor1mix")
    (version "1.3-0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "nor1mix" version))
       (sha256
        (base32
         "1817wcvlmxs70vs4db0jkxd7i037744zz8ay3c2a9949z29fxr4w"))))
    (build-system r-build-system)
    (home-page "https://cran.r-project.org/web/packages/nor1mix/")
    (synopsis "Normal (1-d) mixture models")
    (description
     "This package provides S3 classes and methods for one-dimensional normal
mixture models, for, e.g., density estimation or clustering algorithms
research and teaching; it provides the widely used Marron-Wand densities.  It
also provides tools for efficient random number generation and graphics.")
    (license license:gpl2+)))

(define-public r-beanplot
  (package
    (name "r-beanplot")
    (version "1.2")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "beanplot" version))
       (sha256
        (base32
         "0wmkr704fl8kdxkjwmaxw2a2h5dwzfgsgpncnk2p2wd4768jknj9"))))
    (build-system r-build-system)
    (home-page "https://cran.r-project.org/web/packages/beanplot/")
    (synopsis "Visualization via beanplots")
    (description
     "This package provides beanplots, an alternative to
boxplot/stripchart/violin plots.  It can be used to plot univariate comparison
graphs.")
    (license license:gpl2)))

(define-public r-pbdzmq
  (package
    (name "r-pbdzmq")
    (version "0.3-3")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "pbdZMQ" version))
       (sha256
        (base32
         "1jkfcfhspvqra7vbllrvkz3jx8j7d0ang6zzcdjgpb7200sc29mf"))))
    (properties `((upstream-name . "pbdZMQ")))
    (build-system r-build-system)
    (inputs
     `(("zeromq" ,zeromq)
       ("zlib" ,zlib)))
    (native-inputs
     `(("pkg-config" ,pkg-config)))
    (home-page "https://pbdr.org/")
    (synopsis "R interface to ZeroMQ")
    (description
     "ZeroMQ is a well-known library for high-performance asynchronous
messaging in scalable, distributed applications.  This package provides high
level R wrapper functions to easily utilize ZeroMQ.  The main focus is on
interactive client/server programming frameworks.  A few wrapper functions
compatible with @code{rzmq} are also provided.")
    (license license:gpl3)))

(define-public r-repr
  (package
    (name "r-repr")
    (version "1.1.0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "repr" version))
       (sha256
        (base32
         "15jz780w4nd9qjd1g3gq8f5lkh60p2v3ig3hm5kl1rg3z4cf0gvl"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-base64enc" ,r-base64enc)
       ("r-htmltools" ,r-htmltools)
       ("r-jsonlite" ,r-jsonlite)
       ("r-pillar" ,r-pillar)))
    (home-page "https://cran.r-project.org/web/packages/repr/")
    (synopsis "Serializable representations")
    (description
     "This package provides string and binary representations of objects for
several formats and MIME types.")
    (license license:gpl3)))

(define-public r-irdisplay
  (package
    (name "r-irdisplay")
    (version "0.7.0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "IRdisplay" version))
       (sha256
        (base32
         "12chk53nf4zckgc4yl7gbvd7m5dvli52inp5b3f0zvcjvfncksli"))))
    (properties `((upstream-name . "IRdisplay")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-repr" ,r-repr)))
    (home-page "https://cran.r-project.org/web/packages/IRdisplay/")
    (synopsis "Jupyter display machinery")
    (description
     "This package provides an interface to the rich display capabilities of
Jupyter front-ends (e.g. Jupyter Notebook).  It is designed to be used from a
running IRkernel session.")
    (license license:expat)))

(define-public r-irkernel
  (package
    (name "r-irkernel")
    (version "1.1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "IRkernel" version))
       (sha256
        (base32
         "1viqxs91dys1z4cf7gb59rmqvzb8lc7jdp4azrpmhgwa8qf46s94"))))
    (properties `((upstream-name . "IRkernel")))
    (build-system r-build-system)
    (arguments
     `(#:phases
       (modify-phases %standard-phases
         (add-after 'install 'install-kernelspec
           (lambda* (#:key outputs #:allow-other-keys)
             (let ((out (assoc-ref outputs "out")))
               (setenv "HOME" "/tmp")
               (invoke "jupyter" "kernelspec" "install"
                       "--name" "ir"
                       "--prefix" out
                       (string-append out "/site-library/IRkernel/kernelspec"))
               ;; Record the absolute file name of the 'R' executable in
               ;; 'kernel.json'.
               (substitute* (string-append out "/share/jupyter"
                                           "/kernels/ir/kernel.json")
                 (("\\[\"R\",")
                  (string-append "[\"" (which "R") "\",")))
               #t))))))
    (inputs
     `(("jupyter" ,jupyter)))
    (propagated-inputs
     `(("r-crayon" ,r-crayon)
       ("r-digest" ,r-digest)
       ("r-evaluate" ,r-evaluate)
       ("r-irdisplay" ,r-irdisplay)
       ("r-jsonlite" ,r-jsonlite)
       ;; sets R_LIBS_SITE, so R can actually find this package (IRkernel)
       ("r-minimal" ,r-minimal)
       ("r-pbdzmq" ,r-pbdzmq)
       ("r-repr" ,r-repr)
       ("r-uuid" ,r-uuid)))
    (home-page "https://cran.r-project.org/web/packages/IRkernel/")
    (synopsis "Native R kernel for Jupyter")
    (description
     "The R kernel for the Jupyter environment executes R code which the
front-end (Jupyter Notebook or other front-ends) submits to the kernel via the
network.")
    (license license:expat)))

(define-public r-gmodels
  (package
    (name "r-gmodels")
    (version "2.18.1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "gmodels" version))
       (sha256
        (base32
         "0s8kd8krqk4kwv2zqxpsfy3w8qdwf5naf4b5l383vidq9sil0qb2"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-gdata" ,r-gdata)
       ("r-mass" ,r-mass)))
    (home-page "https://cran.r-project.org/web/packages/gmodels/")
    (synopsis "Various R programming tools for model fitting")
    (description
     "This package provides various R programming tools for model fitting.")
    (license license:gpl2)))

(define-public r-apcluster
  (package
    (name "r-apcluster")
    (version "1.4.8")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "apcluster" version))
       (sha256
        (base32
         "0lzf2jqm56i74wif6x5sw3j0w2qc4sni49zq2fgbl89b7lwkvchj"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-matrix" ,r-matrix)
       ("r-rcpp" ,r-rcpp)))
    (home-page "https://cran.r-project.org/web/packages/apcluster/")
    (synopsis "Affinity propagation clustering")
    (description
     "This package implements affinity propagation clustering introduced by
Frey and Dueck (2007).  The package further provides leveraged affinity
propagation and an algorithm for exemplar-based agglomerative clustering that
can also be used to join clusters obtained from affinity propagation.  Various
plotting functions are available for analyzing clustering results.")
    (license license:gpl2+)))

(define-public r-valr
  (package
    (name "r-valr")
    (version "0.5.0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "valr" version))
       (sha256
        (base32
         "14jhrwkiwmha3vlmm7b50n2xxyizj6ddmy89gb20mpzq7qhz1ika"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-broom" ,r-broom)
       ("r-dplyr" ,r-dplyr)
       ("r-ggplot2" ,r-ggplot2)
       ("r-rcpp" ,r-rcpp)
       ("r-readr" ,r-readr)
       ("r-rlang" ,r-rlang)
       ("r-stringr" ,r-stringr)
       ("r-tibble" ,r-tibble)))
    (home-page "http://github.com/rnabioco/valr")
    (synopsis "Genome interval arithmetic in R")
    (description
     "This package enables you to read and manipulate genome intervals and
signals.  It provides functionality similar to command-line tool suites within
R, enabling interactive analysis and visualization of genome-scale data.")
    (license license:expat)))

(define-public r-rematch2
  (package
    (name "r-rematch2")
    (version "2.1.1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "rematch2" version))
       (sha256
        (base32
         "13siaa8s2ji9q6hykhb2r34ag76335ypmbqr90xaqilbir0klhnh"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-tibble" ,r-tibble)))
    (home-page "https://github.com/r-lib/rematch2")
    (synopsis "Tidy output from regular expression matching")
    (description
     "This package provides wrappers on @code{regexpr} and @code{gregexpr} to
return the match results in tidy data frames.")
    (license license:expat)))

(define-public r-picante
  (package
    (name "r-picante")
    (version "1.8.1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "picante" version))
       (sha256
        (base32
         "1b16zm8zjjsl181b8krkdcrbcw347kf772c4w7y5332qmfi7jhz0"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-ape" ,r-ape)
       ("r-nlme" ,r-nlme)
       ("r-vegan" ,r-vegan)))
    (home-page "https://cran.r-project.org/web/packages/picante/")
    (synopsis "Integrating phylogenies and ecology")
    (description
     "This package provides functions for phylocom integration, community
analyses, null-models, traits and evolution.  It implements numerous
ecophylogenetic approaches including measures of community phylogenetic and
trait diversity, phylogenetic signal, estimation of trait values for
unobserved taxa, null models for community and phylogeny randomizations, and
utility functions for data input/output and phylogeny plotting.  A full
description of package functionality and methods are provided by Kembel et
al. (2010).")
    (license license:gpl2)))

(define-public r-reinforcelearn
  (package
    (name "r-reinforcelearn")
    (version "0.2.1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "reinforcelearn" version))
       (sha256
        (base32
         "176z2q69p24i29a8sh19xxn2zl3h1z2ixdssr5i6m4yvkvdrvv3b"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-checkmate" ,r-checkmate)
       ("r-nnet" ,r-nnet)
       ("r-purrr" ,r-purrr)
       ("r-r6" ,r-r6)))
    (home-page "https://markusdumke.github.io/reinforcelearn")
    (synopsis "Reinforcement learning")
    (description
     "This package implements reinforcement learning environments and
algorithms as described in Sutton & Barto (1998).  The Q-Learning algorithm
can be used with function approximation, eligibility traces (Singh & Sutton,
1996) and experience replay (Mnih et al., 2013).")
    (license license:expat)))

(define-public r-lemon
  (package
    (name "r-lemon")
    (version "0.4.3")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "lemon" version))
       (sha256
        (base32
         "0wsn5bfg10wq4dnrgpyraz2bzx9p19c7hf1pwj3h4zmpqfgsdbpw"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-ggplot2" ,r-ggplot2)
       ("r-gridextra" ,r-gridextra)
       ("r-gtable" ,r-gtable)
       ("r-knitr" ,r-knitr)
       ("r-lattice" ,r-lattice)
       ("r-plyr" ,r-plyr)
       ("r-scales" ,r-scales)))
    (home-page "https://github.com/stefanedwards/lemon")
    (synopsis "Freshen up your ggplot2 plots")
    (description
     "This package provides functions for working with legends and axis lines
of ggplot2, facets that repeat axis lines on all panels, and some knitr
extensions.")
    (license license:gpl3)))

(define-public r-wgaim
  (package
    (name "r-wgaim")
    (version "2.0-1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "wgaim" version))
       (sha256
        (base32 "1qiyfkpsbzjr9xsq5kqq6rlqpndngkn2irdfh3gyi45h6hn118j4"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-ggplot2" ,r-ggplot2)
       ("r-qtl" ,r-qtl)))
    (home-page "https://cran.r-project.org/web/packages/wgaim")
    (synopsis "Whole genome average interval mapping for QTL detection")
    (description
     "This package integrates sophisticated mixed modelling methods with a
whole genome approach to detecting significant QTL in linkage maps.")
    (license license:gpl2+)))

(define-public r-bedr
  (package
    (name "r-bedr")
    (version "1.0.7")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "bedr" version))
       (sha256
        (base32
         "0zpqvyjgwyqawxm8qrhcv8zq2b3yxgcqkkc87br29yrl7sjb8h6j"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-data-table" ,r-data-table)
       ("r-r-utils" ,r-r-utils)
       ("r-testthat" ,r-testthat)
       ("r-venndiagram" ,r-venndiagram)
       ("r-yaml" ,r-yaml)
       ("bedops" ,bedops)
       ("bedtools" ,bedtools)
       ("htslib" ,htslib))) ; for tabix
    (native-inputs
     `(("r-knitr" ,r-knitr))) ; for vignettes
    (home-page "https://cran.r-project.org/web/packages/bedr")
    (synopsis "Genomic region processing")
    (description
     "This package is for genomic regions processing using command line tools
such as BEDTools, BEDOPS and Tabix.  These tools offer scalable and efficient
utilities to perform genome arithmetic e.g indexing, formatting and merging.
The bedr package's API enhances access to these tools as well as offers
additional utilities for genomic regions processing.")
    (license license:gpl2)))

(define-public r-sets
  (package
    (name "r-sets")
    (version "1.0-18")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "sets" version))
       (sha256
        (base32
         "16v7650p47khqrbbw0z98llmwmmhswqmhri0n7nrfhdqwmby1lbl"))))
    (properties `((upstream-name . "sets")))
    (build-system r-build-system)
    (home-page "https://cran.r-project.org/web/packages/sets")
    (synopsis "Sets, generalized sets, customizable sets and intervals")
    (description
     "This package provides data structures and basic operations for ordinary
sets, generalizations such as fuzzy sets, multisets, and fuzzy multisets,
customizable sets, and intervals.")
    (license license:gpl2)))

(define-public r-partitions
  (package
    (name "r-partitions")
    (version "1.9-22")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "partitions" version))
       (sha256
        (base32
         "1qqy4df28wy4q0g572azrj171jlhvrnzbh7x0wr2g7v6gr20y0ns"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-gmp" ,r-gmp)
       ("r-polynom" ,r-polynom)
       ("r-sets" ,r-sets)))
    (home-page "https://cran.r-project.org/web/packages/partitions")
    (synopsis "Additive partitions of integers")
    (description
     "This package provides tools to enumerates the partitions, unequal
partitions, and restricted partitions of an integer; the three corresponding
partition functions are also given.")
    ;; Any version of the GPL
    (license license:gpl2+)))

(define-public r-brobdingnag
  (package
    (name "r-brobdingnag")
    (version "1.2-6")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "Brobdingnag" version))
       (sha256
        (base32
         "1m3ajvcksqfck5l5hj5xiflj4ry6d896ybv4f0xxks8chgnwmv0r"))))
    (properties `((upstream-name . "Brobdingnag")))
    (build-system r-build-system)
    (home-page "https://github.com/RobinHankin/Brobdingnag.git")
    (synopsis "Very large numbers in R")
    (description
     "This package handles very large numbers in R.  Real numbers are held
using their natural logarithms, plus a logical flag indicating sign.  The
package includes a vignette that gives a step-by-step introduction to using S4
methods.")
    ;; Any version of the GPL
    (license license:gpl2+)))

(define-public r-untb
  (package
    (name "r-untb")
    (version "1.7-4")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "untb" version))
       (sha256
        (base32
         "1i7m4vfslsix98dwx4jlrsldm7fhhfp25gr7aapcxqxms7ryaby6"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-brobdingnag" ,r-brobdingnag)
       ("r-partitions" ,r-partitions)
       ("r-polynom" ,r-polynom)))
    (home-page "https://github.com/RobinHankin/untb.git")
    (synopsis "Ecological drift under the UNTB")
    (description
     "This package provides numerical simulations, and visualizations, of
Hubbell's @dfn{Unified Neutral Theory of Biodiversity} (UNTB).")
    (license license:gpl2+)))

(define-public r-stepwise
  (package
    (name "r-stepwise")
    (version "0.3")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "stepwise" version))
       (sha256
        (base32
         "1lbx1bxwkf9dw6q46w40pp7h5nkxgghmx8rkpaymm6iybc7gyir2"))))
    (build-system r-build-system)
    (home-page "https://stat.sfu.ca/statgen/research/stepwise.html")
    (synopsis "Stepwise detection of recombination breakpoints")
    (description
     "This package provides a stepwise approach to identifying recombination
breakpoints in a genomic sequence alignment.")
    (license license:gpl2+)))

(define-public r-snpmaxsel
  (package
    (name "r-snpmaxsel")
    (version "1.0-3")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "SNPmaxsel" version))
       (sha256
        (base32
         "0pjvixwqzjd3jwccc8yqq9c76afvbmfq0z1w0cwyj8bblrjpx13z"))))
    (properties `((upstream-name . "SNPmaxsel")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-combinat" ,r-combinat)
       ("r-mvtnorm" ,r-mvtnorm)))
    (home-page "https://cran.r-project.org/web/packages/SNPmaxsel/index.html")
    (synopsis "Maximally selected statistics for SNP data")
    (description
     "This package implements asymptotic methods related to maximally selected
statistics, with applications to @dfn{single-nucleotide polymorphism} (SNP)
data.")
    (license license:gpl2+)))

(define-public r-acsnminer
  (package
    (name "r-acsnminer")
    (version "0.16.8.25")
    (source (origin
              (method url-fetch)
              (uri (cran-uri "ACSNMineR" version))
              (sha256
               (base32
                "0gh604s8qall6zfjlwcg2ilxjvz08dplf9k5g47idhv43scm748l"))))
    (properties `((upstream-name . "ACSNMineR")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-ggplot2" ,r-ggplot2)
       ("r-gridextra" ,r-gridextra)))
    (home-page "https://cran.r-project.org/web/packages/ACSNMineR")
    (synopsis "Gene enrichment analysis")
    (description
     "This package provides tools to compute and represent gene set enrichment
or depletion from your data based on pre-saved maps from the @dfn{Atlas of
Cancer Signalling Networks} (ACSN) or user imported maps.  The gene set
enrichment can be run with hypergeometric test or Fisher exact test, and can
use multiple corrections.  Visualization of data can be done either by
barplots or heatmaps.")
    (license license:gpl2+)))

(define-public r-seqinr
  (package
    (name "r-seqinr")
    (version "3.6-1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "seqinr" version))
       (sha256
        (base32
         "0j30za6kji6y3v09cvcydiacnp65pv6ig8aw7cydl47l5s9chky4"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-ade4" ,r-ade4)
       ("r-segmented" ,r-segmented)))
    (inputs
     `(("zlib" ,zlib)))
    (home-page "http://seqinr.r-forge.r-project.org/")
    (synopsis "Biological sequences retrieval and analysis")
    (description
     "This package provides tools for exploratory data analysis and data
visualization of biological sequence (DNA and protein) data.  It also includes
utilities for sequence data management under the ACNUC system.")
    (license license:gpl2+)))

(define-public r-units
  (package
    (name "r-units")
    (version "0.6-6")
    (source
      (origin
        (method url-fetch)
        (uri (cran-uri "units" version))
        (sha256
          (base32
            "11x6xz1fbml28xmrhgn4sii9vfyj3gyfc1dfxahdg9cszdmcgdnh"))))
    (build-system r-build-system)
    (inputs
     `(("udunits" ,udunits)))
    (propagated-inputs
     `(("r-rcpp" ,r-rcpp)))
    (native-inputs
     `(("r-knitr" ,r-knitr)))
    (home-page "https://github.com/r-quantities/units/")
    (synopsis "Measurement Units for R Vectors")
    (description
      "This package provides support for measurement units in R vectors,
matrices and arrays: automatic propagation, conversion, derivation and
simplification of units; raising errors in case of unit incompatibility.  It
is compatible with the @code{POSIXct}, @code{Date} and @code{difftime}
classes.")
    (license license:gpl2)))

(define-public r-classint
  (package
    (name "r-classint")
    (version "0.4-2")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "classInt" version))
       (sha256
        (base32
         "0w980hrw8sgfdfyd5dsimalq7gwhvqm7507abk7k363pvgks23dv"))))
    (properties `((upstream-name . "classInt")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-class" ,r-class)
       ("r-e1071" ,r-e1071)
       ("r-kernsmooth" ,r-kernsmooth)))
    (native-inputs `(("gfortran" ,gfortran)))
    (home-page "https://github.com/r-spatial/classInt/")
    (synopsis "Choose univariate class intervals")
    (description
     "This package provides selected commonly used methods for choosing
univariate class intervals for mapping or other graphics purposes.")
    (license license:gpl2+)))

(define-public r-spdata
  (package
    (name "r-spdata")
    (version "0.3.3")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "spData" version))
       (sha256
        (base32
         "1v66qkvsx77hvv5c78v760yp0hknf7xzcjir2ri3ha456mz79yl5"))))
    (properties `((upstream-name . "spData")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-raster" ,r-raster)
       ("r-sp" ,r-sp)))
    (home-page "https://github.com/Nowosad/spData")
    (synopsis "Datasets for spatial analysis")
    (description
     "This a package containing diverse spatial datasets for demonstrating,
benchmarking and teaching spatial data analysis.  It includes R data of class
@code{sf}, @code{Spatial}, and @code{nb}.  It also contains data stored in a
range of file formats including GeoJSON, ESRI Shapefile and GeoPackage.  Some
of the datasets are designed to illustrate specific analysis techniques.
@code{cycle_hire()} and @code{cycle_hire_osm()}, for example, are designed to
illustrate point pattern analysis techniques.")
    (license license:cc0)))

(define-public r-learnbayes
  (package
    (name "r-learnbayes")
    (version "2.15.1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "LearnBayes" version))
       (sha256
        (base32
         "0ch54v2zz2yyyk0lvn5rfikdmyz1qh9j1wk3585wl8v58mc0h4cv"))))
    (properties `((upstream-name . "LearnBayes")))
    (build-system r-build-system)
    (home-page "https://cran.r-project.org/web/packages/LearnBayes")
    (synopsis "Functions for learning Bayesian inference")
    (description
     "This package provides a collection of functions helpful in learning the
basic tenets of Bayesian statistical inference.  It contains functions for
summarizing basic one and two parameter posterior distributions and predictive
distributions.  It contains MCMC algorithms for summarizing posterior
distributions defined by the user.  It also contains functions for regression
models, hierarchical models, Bayesian tests, and illustrations of Gibbs
sampling.")
    (license license:gpl2+)))

(define-public r-deldir
  (package
    (name "r-deldir")
    (version "0.1-25")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "deldir" version))
       (sha256
        (base32
         "0kdglv8rc1pb4ilcid4xc9wpv5kkj2y6x6wg7919k3hya7mz58ph"))))
    (build-system r-build-system)
    (native-inputs `(("gfortran" ,gfortran)))
    (home-page "https://cran.r-project.org/web/packages/deldir")
    (synopsis "Delaunay triangulation and Dirichlet (Voronoi) tessellation")
    (description
     "This package provides tools for calculating the Delaunay triangulation
and the Dirichlet or Voronoi tessellation (with respect to the entire plane)
of a planar point set.  It plots triangulations and tessellations in various
ways, clips tessellations to sub-windows, calculates perimeters of
tessellations, and summarizes information about the tiles of the
tessellation.")
    (license license:gpl2+)))

(define-public r-sf
  (package
    (name "r-sf")
    (version "0.9-0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "sf" version))
       (sha256
        (base32
         "117r9l3v7nkdj9bfy6qr0yz0gd5bv0pwnkc9vk2gv3xqj0h1fpf6"))))
    (build-system r-build-system)
    (inputs
     `(("gdal" ,gdal)
       ("geos" ,geos)
       ("proj" ,proj.4)
       ("zlib" ,zlib)))
    (propagated-inputs
     `(("r-classint" ,r-classint)
       ("r-dbi" ,r-dbi)
       ("r-magrittr" ,r-magrittr)
       ("r-rcpp" ,r-rcpp)
       ("r-units" ,r-units)))
    (native-inputs
     `(("pkg-config" ,pkg-config)
       ("r-knitr" ,r-knitr)))
    (home-page "https://github.com/r-spatial/sf/")
    (synopsis "Simple features for R")
    (description
     "This package provides support for simple features, a standardized way to
encode spatial vector data.  It binds to GDAL for reading and writing data, to
GEOS for geometrical operations, and to PROJ for projection conversions and
datum transformations.")
    ;; Either of these licenses
    (license (list license:gpl2 license:expat))))

(define-public r-spdep
  (package
    (name "r-spdep")
    (version "1.1-3")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "spdep" version))
       (sha256
        (base32
         "1f8cjffqqc6rnb3n4qym70ca6nz2kvrsd3g587wrqdr79nnbwnrk"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-boot" ,r-boot)
       ("r-coda" ,r-coda)
       ("r-deldir" ,r-deldir)
       ("r-expm" ,r-expm)
       ("r-gmodels" ,r-gmodels)
       ("r-learnbayes" ,r-learnbayes)
       ("r-mass" ,r-mass)
       ("r-matrix" ,r-matrix)
       ("r-nlme" ,r-nlme)
       ("r-sf" ,r-sf)
       ("r-sp" ,r-sp)
       ("r-spdata" ,r-spdata)))
    (home-page "https://github.com/r-spatial/spdep/")
    (synopsis "Spatial dependence: weighting schemes, statistics and models")
    (description
     "This package provides a collection of functions to create spatial
weights matrix objects from polygon contiguities, from point patterns by
distance and tessellations, for summarizing these objects, and for permitting
their use in spatial data analysis, including regional aggregation by minimum
spanning tree.")
    (license license:gpl2+)))

(define-public r-adegenet
  (package
    (name "r-adegenet")
    (version "2.1.2")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "adegenet" version))
       (sha256
        (base32
         "01fgrgbiddz2q4l3mx637hhwbs7r0c43yw7vpwl8p8pwbm3nykz0"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-ade4" ,r-ade4)
       ("r-ape" ,r-ape)
       ("r-boot" ,r-boot)
       ("r-dplyr" ,r-dplyr)
       ("r-ggplot2" ,r-ggplot2)
       ("r-igraph" ,r-igraph)
       ("r-mass" ,r-mass)
       ("r-reshape2" ,r-reshape2)
       ("r-seqinr" ,r-seqinr)
       ("r-shiny" ,r-shiny)
       ("r-spdep" ,r-spdep)
       ("r-vegan" ,r-vegan)))
    (home-page "https://github.com/thibautjombart/adegenet")
    (synopsis "Exploratory analysis of genetic and genomic data")
    (description
     "This package provides a toolset for the exploration of genetic and
genomic data.  Adegenet provides formal (S4) classes for storing and handling
various genetic data, including genetic markers with varying ploidy and
hierarchical population structure (@code{genind} class), alleles counts by
populations (@code{genpop}), and genome-wide SNP data (@code{genlight}).  It
also implements original multivariate methods (DAPC, sPCA), graphics,
statistical tests, simulation tools, distance and similarity measures, and
several spatial methods.  A range of both empirical and simulated datasets is
also provided to illustrate various methods.")
    (license license:gpl2+)))

(define-public r-pegas
  (package
    (name "r-pegas")
    (version "0.13")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "pegas" version))
       (sha256
        (base32 "002i7s4g0nhnq0v05gs0yssqiyhpq2f7rw2rhn31hsbgxc86frvy"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-adegenet" ,r-adegenet)
       ("r-ape" ,r-ape)))
    (home-page "http://ape-package.ird.fr/pegas.html")
    (synopsis "Population and evolutionary genetics analysis system")
    (description
     "This package provides functions for reading, writing, plotting,
analysing, and manipulating allelic and haplotypic data, including from VCF
files, and for the analysis of population nucleotide sequences and
micro-satellites including coalescent analyses, linkage disequilibrium,
population structure (Fst, Amova) and equilibrium (HWE), haplotype networks,
minimum spanning tree and network, and median-joining networks.")
    (license license:gpl2+)))

(define-public r-rmetasim
  (package
    (name "r-rmetasim")
    (version "3.1.14")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "rmetasim" version))
       (sha256
        (base32
         "0rdkhfgyr97r2d1kd9g8ipb2pn563qxm1y4m9z678q0kqan2ddl0"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-ade4" ,r-ade4)
       ("r-adegenet" ,r-adegenet)
       ("r-gtools" ,r-gtools)
       ("r-pegas" ,r-pegas)))
    (home-page "https://cran.r-project.org/web/packages/rmetasim")
    (synopsis "Individual-based population genetic simulation environment")
    (description
     "This package provides an interface between R and the metasim simulation
engine.  The simulation environment is documented in: Strand, A.(2002),
Metasim 1.0: an individual-based environment for simulating population
genetics of complex population dynamics.")
    ;; Any GPL version
    (license license:gpl2+)))

(define-public r-genetics
  (package
    (name "r-genetics")
    (version "1.3.8.1.2")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "genetics" version))
       (sha256
        (base32
         "1v0ylnia6c44v356dsmnkx6054vcxazpzsrdh3yph5ch5vg6gjrh"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-combinat" ,r-combinat)
       ("r-gdata" ,r-gdata)
       ("r-gtools" ,r-gtools)
       ("r-mass" ,r-mass)
       ("r-mvtnorm" ,r-mvtnorm)))
    (home-page "https://cran.r-project.org/web/packages/genetics/")
    (synopsis "Population genetics")
    (description
     "This package provides classes and methods for handling genetic data.
It includes classes to represent genotypes and haplotypes at single markers up
to multiple markers on multiple chromosomes.  Function include allele
frequencies, flagging homo/heterozygotes, flagging carriers of certain
alleles, estimating and testing for Hardy-Weinberg disequilibrium, estimating
and testing for linkage disequilibrium, ...")
    ;; Any GPL version.
    (license license:gpl2+)))

(define-public r-snp-plotter
  (package
    (name "r-snp-plotter")
    (version "0.5.1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "snp.plotter" version))
       (sha256
        (base32
         "16apsqvkah5l0d5qcwp3lq2jspkb6n62wzr0wskmj84jblx483vv"))))
    (properties `((upstream-name . "snp.plotter")))
    (build-system r-build-system)
    (propagated-inputs `(("r-genetics" ,r-genetics)))
    (home-page "https://cran.r-project.org/web/packages/snp.plotter/")
    (synopsis "Plot p-values using single SNP and/or haplotype data")
    (description
     "This package helps you create plots of p-values using single SNP and/or
haplotype data.  Main features of the package include options to display a
@dfn{linkage disequilibrium} (LD) plot and the ability to plot multiple
datasets simultaneously.  Plots can be created using global and/or individual
haplotype p-values along with single SNP p-values.  Images are created as
either PDF/EPS files.")
    (license license:gpl2+)))

(define-public r-polspline
  (package
    (name "r-polspline")
    (version "1.1.17")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "polspline" version))
       (sha256
        (base32 "0c7fnxpqpy3hibiim4yib6l6bq363s97wwvllxp4lp8h06fjcyyn"))))
    (build-system r-build-system)
    (native-inputs `(("gfortran" ,gfortran)))
    (home-page "https://cran.r-project.org/web/packages/polspline/")
    (synopsis "Polynomial spline routines")
    (description
     "This package provides routines for the polynomial spline fitting
routines hazard regression, hazard estimation with flexible tails, logspline,
lspec, polyclass, and polymars.")
    (license license:gpl2+)))

(define-public r-rms
  (package
    (name "r-rms")
    (version "5.1-4")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "rms" version))
       (sha256
        (base32 "19knh1sw0icw6jh9wfb2hq5jf49i2qfvp9myvqm5paa495689x9q"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-ggplot2" ,r-ggplot2)
       ("r-hmisc" ,r-hmisc)
       ("r-htmltable" ,r-htmltable)
       ("r-htmltools" ,r-htmltools)
       ("r-lattice" ,r-lattice)
       ("r-multcomp" ,r-multcomp)
       ("r-nlme" ,r-nlme)
       ("r-polspline" ,r-polspline)
       ("r-quantreg" ,r-quantreg)
       ("r-rpart" ,r-rpart)
       ("r-sparsem" ,r-sparsem)
       ("r-survival" ,r-survival)))
    (native-inputs `(("gfortran" ,gfortran)))
    (home-page "http://biostat.mc.vanderbilt.edu/rms")
    (synopsis "Regression modeling strategies")
    (description
     "This is a package for regression modeling, testing, estimation,
validation, graphics, prediction, and typesetting by storing enhanced model
design attributes in the fit.  The rms package is a collection of functions
that assist with and streamline modeling.  It also contains functions for
binary and ordinal logistic regression models, ordinal models for continuous Y
with a variety of distribution families, and the Buckley-James multiple
regression model for right-censored responses, and implements penalized
maximum likelihood estimation for logistic and ordinary linear models.  The
package works with almost any regression model, but it was especially written
to work with binary or ordinal regression models, Cox regression, accelerated
failure time models, ordinary linear models, the Buckley-James model,
generalized least squares for serially or spatially correlated observations,
generalized linear models, and quantile regression.")
    (license license:gpl2+)))

(define-public r-haplo-stats
  (package
    (name "r-haplo-stats")
    (version "1.7.9")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "haplo.stats" version))
       (sha256
        (base32
         "19kxascqq5qz0zdxx0w837ji207y1z2ggxkl4vmlbay03k2dw2mx"))))
    (properties `((upstream-name . "haplo.stats")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-rms" ,r-rms)))
    (native-inputs
     `(("r-r-rsp" ,r-r-rsp))) ; for vignettes
    (home-page "https://www.mayo.edu/research/labs/statistical-genetics-genetic-epidemiology/software")
    (synopsis "Analysis of haplotypes when linkage phase is ambiguous")
    (description
     "This package provides routines for the analysis of indirectly measured
haplotypes.  The statistical methods assume that all subjects are unrelated
and that haplotypes are ambiguous (due to unknown linkage phase of the genetic
markers).  The main functions are: @code{haplo.em()}, @code{haplo.glm()},
@code{haplo.score()}, and @code{haplo.power()}; all of which have detailed
examples in the vignette.")
    (license license:gpl2+)))

(define-public r-bqtl
  (package
    (name "r-bqtl")
    (version "1.0-32")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "bqtl" version))
       (sha256
        (base32
         "0jjqgsm9fmvz5nkgz608xfljjpmaf4rs4f7kxvpqn4b1l9s5lhci"))))
    (build-system r-build-system)
    (native-inputs `(("gfortran" ,gfortran)))
    (home-page "http://famprevmed.ucsd.edu/faculty/cberry/bqtl/")
    (synopsis "Bayesian QTL mapping toolkit")
    (description
     "This is a QTL mapping toolkit for inbred crosses and recombinant inbred
lines.  It includes maximum likelihood and Bayesian tools.")
    (license license:gpl2+)))

(define-public r-ibdreg
  (package
    (name "r-ibdreg")
    (version "0.2.5")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "ibdreg" version))
       (sha256
        (base32
         "1kaa5q1byi30wzr0mw4w2cv1ssxprzcwf91wrpqwkgcsdy7dkh2g"))))
    (build-system r-build-system)
    (home-page "https://www.mayo.edu/research/labs/\
statistical-genetics-genetic-epidemiology/software")
    (synopsis "Regression methods for IBD linkage with covariates")
    (description
     "This package provides a method to test genetic linkage with covariates
by regression methods with response IBD sharing for relative pairs.  Account
for correlations of IBD statistics and covariates for relative pairs within
the same pedigree.")
    (license license:gpl2+)))

(define-public r-dlmap
  (package
    (name "r-dlmap")
    (version "1.13")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "dlmap" version))
       (sha256
        (base32
         "0s6wlkggkm3qndwyvw72xv1n0mcjb7ss3ajbq2ll6rv30splq0db"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-ibdreg" ,r-ibdreg)
       ("r-mgcv" ,r-mgcv)
       ("r-nlme" ,r-nlme)
       ("r-qtl" ,r-qtl)
       ("r-wgaim" ,r-wgaim)))
    (home-page "https://cran.r-project.org/web/packages/dlmap/")
    (synopsis "Detection localization mapping for QTL")
    (description
     "This is package for QTL mapping in a mixed model framework with separate
detection and localization stages.  The first stage detects the number of QTL
on each chromosome based on the genetic variation due to grouped markers on
the chromosome; the second stage uses this information to determine the most
likely QTL positions.  The mixed model can accommodate general fixed and
random effects, including spatial effects in field trials and pedigree
effects.  It is applicable to backcrosses, doubled haploids, recombinant
inbred lines, F2 intercrosses, and association mapping populations.")
    (license license:gpl2)))

(define-public r-ldheatmap
  (package
    (name "r-ldheatmap")
    (version "0.99-7")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "LDheatmap" version))
       (sha256
        (base32
         "1r0j8bihi5z1x0sgaf7dwzpsw9i0nc1vylvipvc0cia2ka1lr9dc"))))
    (properties `((upstream-name . "LDheatmap")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-genetics" ,r-genetics)
       ("r-rcpp" ,r-rcpp)
       ("r-snpstats" ,r-snpstats)))
    (home-page "https://stat.sfu.ca/statgen/research/ldheatmap.html")
    (synopsis "Graphical display of pairwise linkage disequilibria between SNPs")
    (description
     "This package provides tools to produce a graphical display, as a heat
map, of measures of pairwise linkage disequilibria between SNPs.  Users may
optionally include the physical locations or genetic map distances of each SNP
on the plot.")
    (license license:gpl3)))

(define-public r-hwde
  (package
    (name "r-hwde")
    (version "0.67")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "hwde" version))
       (sha256
        (base32
         "0wb2f9i5qi7w77ygh8bvydfpr7j5x8dyvnnhdkajaz0wdcpkyaqy"))))
    (build-system r-build-system)
    (home-page "https://cran.r-project.org/web/packages/hwde/")
    (synopsis "Models and tests for departure from Hardy-Weinberg equilibrium")
    (description
     "This package fits models for genotypic disequilibria, as described in
Huttley and Wilson (2000), Weir (1996) and Weir and Wilson (1986).  Contrast
terms are available that account for first order interactions between loci.
It also implements, for a single locus in a single population, a conditional
exact test for Hardy-Weinberg equilibrium.")
    (license license:gpl2+)))

(define-public r-tdthap
  (package
    (name "r-tdthap")
    (version "1.1-11")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "tdthap" version))
       (sha256
        (base32
         "15qlj2bivvz3pizd8dq34wczbkbxhzqh3cqp1ixkdkprlyvcxj5k"))))
    (build-system r-build-system)
    (home-page "https://cran.r-project.org/web/packages/tdthap/")
    (synopsis "TDT tests for extended haplotypes")
    (description
     "Functions and examples are provided for transmission/disequilibrium
tests for extended marker haplotypes, as in Clayton, D. and Jones, H. (1999)
\"Transmission/disequilibrium tests for extended marker haplotypes\".")
    (license license:artistic2.0)))

(define-public r-sparql
  (package
    (name "r-sparql")
    (version "1.16")
    (source (origin
              (method url-fetch)
              (uri (cran-uri "SPARQL" version))
              (sha256
               (base32
                "0gak1q06yyhdmcxb2n3v0h9gr1vqd0viqji52wpw211qp6r6dcrc"))))
    (properties `((upstream-name . "SPARQL")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-rcurl" ,r-rcurl)
       ("r-xml" ,r-xml)))
    (home-page "https://cran.r-project.org/web/packages/SPARQL")
    (synopsis "SPARQL client for R")
    (description "This package provides an interface to use SPARQL to pose
SELECT or UPDATE queries to an end-point.")
    ;; The only license indication is found in the DESCRIPTION file,
    ;; which states GPL-3.  So we cannot assume GPLv3+.
    (license license:gpl3)))

(define-public r-bookdown
  (package
    (name "r-bookdown")
    (version "0.18")
    (source (origin
              (method url-fetch)
              (uri (cran-uri "bookdown" version))
              (sha256
               (base32
                "1my6g16phx21v5cvfqcnjibh3zcv02xkix347aafd6a7r3hnxpq5"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-htmltools" ,r-htmltools)
       ("r-knitr" ,r-knitr)
       ("r-rmarkdown" ,r-rmarkdown)
       ("r-tinytex" ,r-tinytex)
       ("r-xfun" ,r-xfun)
       ("pandoc" ,ghc-pandoc)))
    (home-page "https://github.com/rstudio/bookdown")
    (synopsis "Authoring books and technical documents with R markdown")
    (description "This package provides output formats and utilities for
authoring books and technical documents with R Markdown.")
    (license license:gpl3)))

(define-public r-optparse
  (package
    (name "r-optparse")
    (version "1.6.4")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "optparse" version))
       (sha256
        (base32
         "0wyrc42ja3ab5szx46zmz8lm7vzfqxkjca0m0sms8g9hqbmmay6d"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-getopt" ,r-getopt)))
    (home-page "https://github.com/trevorld/optparse")
    (synopsis "Command line option parser")
    (description
     "This package provides a command line parser inspired by Python's
@code{optparse} library to be used with Rscript to write shebang scripts
that accept short and long options.")
    (license license:gpl2+)))

(define-public r-wgcna
  (package
    (name "r-wgcna")
    (version "1.69")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "WGCNA" version))
       (sha256
        (base32
         "022hkprnrafvggi8pkjffkvk1qlnibmbbxxrni00wkrdbga5589f"))))
    (properties `((upstream-name . "WGCNA")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-annotationdbi" ,r-annotationdbi)
       ("r-doparallel" ,r-doparallel)
       ("r-dynamictreecut" ,r-dynamictreecut)
       ("r-fastcluster" ,r-fastcluster)
       ("r-foreach" ,r-foreach)
       ("r-go-db" ,r-go-db)
       ("r-hmisc" ,r-hmisc)
       ("r-impute" ,r-impute)
       ("r-rcpp" ,r-rcpp)
       ("r-survival" ,r-survival)
       ("r-matrixstats" ,r-matrixstats)
       ("r-preprocesscore" ,r-preprocesscore)))
    (home-page
     "http://www.genetics.ucla.edu/labs/horvath/CoexpressionNetwork/Rpackages/WGCNA/")
    (synopsis "Weighted correlation network analysis")
    (description
     "This package provides functions necessary to perform Weighted
Correlation Network Analysis on high-dimensional data.  It includes functions
for rudimentary data cleaning, construction and summarization of correlation
networks, module identification and functions for relating both variables and
modules to sample traits.  It also includes a number of utility functions for
data manipulation and visualization.")
    (license license:gpl2+)))

(define-public r-kernlab
  (package
    (name "r-kernlab")
    (version "0.9-29")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "kernlab" version))
       (sha256
        (base32 "0vqhndl4zm7pvkfvq0f6i9cbrm7pij6kmdp7d7w39pa100x6knn3"))))
    (build-system r-build-system)
    (home-page "https://cran.r-project.org/web/packages/kernlab")
    (synopsis "Kernel-based machine learning tools")
    (description
     "This package provides kernel-based machine learning methods for
classification, regression, clustering, novelty detection, quantile regression
and dimensionality reduction.  Among other methods @code{kernlab} includes
Support Vector Machines, Spectral Clustering, Kernel PCA, Gaussian Processes
and a QP solver.")
    (license license:gpl2)))

(define-public r-hierfstat
  (package
    (name "r-hierfstat")
    (version "0.04-22")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "hierfstat" version))
       (sha256
        (base32
         "1fav2v2996v5kb1ffa6v5wxfm921syxg6as034vd3j4jfhdibyfx"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-ade4" ,r-ade4)
       ("r-adegenet" ,r-adegenet)
       ("r-gtools" ,r-gtools)))
    (home-page "https://cran.r-project.org/web/packages/hierfstat/")
    (synopsis "Estimation and tests of hierarchical F-statistics")
    (description
     "This package allows the estimation of hierarchical F-statistics from
haploid or diploid genetic data with any numbers of levels in the hierarchy,
following the algorithm of Yang (Evolution, 1998, 52(4):950-956).  Functions
are also given to test via randomisations the significance of each F and
variance components, using the likelihood-ratio statistics G.")
    (license license:gpl2+)))

(define-public r-hapassoc
  (package
    (name "r-hapassoc")
    (version "1.2-8")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "hapassoc" version))
       (sha256
        (base32
         "0qs5jl0snzfchgpp6pabncwywxcmi743g91jvjiyyzw0lw85yv4s"))))
    (build-system r-build-system)
    (home-page "https://stat.sfu.ca/statgen/research/hapassoc.html")
    (synopsis "Inference of trait associations with SNP haplotypes")
    (description
     "Hapassoc performs likelihood inference of trait associations with
haplotypes and other covariates in @dfn{generalized linear models} (GLMs). The
functions are developed primarily for data collected in cohort or
cross-sectional studies.  They can accommodate uncertain haplotype phase and
handle missing genotypes at some SNPs.")
    (license license:gpl2)))

(define-public r-sampling
  (package
    (name "r-sampling")
    (version "2.8")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "sampling" version))
       (sha256
        (base32
         "06pj7dan0mknpsblmlnk7am78qrnwgnql5vvx7vmbfvib7rj6s9m"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-lpsolve" ,r-lpsolve)
       ("r-mass" ,r-mass)))
    (home-page "https://cran.r-project.org/web/packages/sampling/")
    (synopsis "Survey sampling")
    (description
     "This package provides functions for drawing and calibrating samples.")
    (license license:gpl2+)))

(define-public r-r2html
  (package
    (name "r-r2html")
    (version "2.3.2")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "R2HTML" version))
       (sha256
        (base32
         "00kxny7hajs9r2kw63qk7d03ggdxx2j1g8vbrmzp806y8aczvik9"))))
    (properties `((upstream-name . "R2HTML")))
    (build-system r-build-system)
    (home-page "https://github.com/nalimilan/R2HTML")
    (synopsis "HTML export for R objects")
    (description
     "This package includes HTML functions and methods to write in an HTML
file.  Thus, making HTML reports is easy.  It includes a function that allows
redirection on the fly, which appears to be very useful for teaching purposes,
as the student can keep a copy of the produced output to keep all that they
did during the course.  The package comes with a vignette describing how to
write HTML reports for statistical analysis.  Finally, a driver for Sweave
parses HTML flat files containing R code and to automatically write
the corresponding outputs (tables and graphs).")
    (license license:gpl2+)))

(define-public r-rjava
  (package
    (name "r-rjava")
    (version "0.9-12")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "rJava" version))
       (sha256
        (base32
         "03vv0pj6san03c51iyqsyb1rwh3097dfpl2s8iswzzmc7k3shj12"))))
    (properties `((upstream-name . "rJava")))
    (build-system r-build-system)
    (arguments
     `(#:modules ((guix build utils)
                  (guix build r-build-system)
                  (ice-9 match))
       #:phases
       (modify-phases %standard-phases
         (add-after 'unpack 'set-JAVA_HOME
           (lambda* (#:key inputs #:allow-other-keys)
             (let ((jdk (assoc-ref inputs "jdk")))
               (setenv "JAVA_HOME" jdk)
               (setenv "JAVA" (which "java"))
               (setenv "JAR" (which "jar"))
               (setenv "JAVAC" (which "javac"))
               (setenv "JAVAH" (which "javah"))
               (setenv "JAVA_CPPFLAGS"
                       (string-append "-I" jdk "/include "
                                      "-I" jdk "/include/linux"))
               (match (find-files (string-append jdk "/jre/lib/") "libjvm.so")
                 ((lib) (setenv "JAVA_LIBS" lib))
                 (_ (error "Could not find libjvm.so"))))
             #t)))))
    (inputs
     `(("icu4c" ,icu4c)
       ("jdk" ,icedtea-8 "jdk")
       ("pcre" ,pcre)
       ("zlib" ,zlib)))
    (home-page "https://www.rforge.net/rJava/")
    (synopsis "Low-Level R to Java interface")
    (description
     "This package provides a low-level interface to the Java VM very much
like .C/.Call and friends.  It allows the creation of objects, calling methods
and accessing fields.")
    (license license:gpl2)))

(define-public r-svmisc
  (package
    (name "r-svmisc")
    (version "1.1.0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "svMisc" version))
       (sha256
        (base32
         "01r2a73wx2sh1njky961fxabx5wgddqqjqba6vjg0f3h8r3abmn2"))))
    (properties `((upstream-name . "svMisc")))
    (build-system r-build-system)
    (home-page "https://github.com/SciViews/svMisc")
    (synopsis "Miscellaneous functions for SciViews")
    (description
     "This package provides miscellaneous functions for SciViews or general
use, including tools to manage a temporary environment attached to the search
path for temporary variables you do not want to @code{save()} or
@code{load()}; test the current platform; showing progress bars, etc.")
    (license license:gpl2)))

(define-public r-xyz
  (package
    (name "r-xyz")
    (version "0.2")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "xyz" version))
       (sha256
        (base32
         "13w4sb4pvgciwr8wsz785dafj2k2kpx7znz46r5d32wx88vkycp4"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-rcpp" ,r-rcpp)))
    (home-page "https://cran.r-project.org/web/packages/xyz/")
    (synopsis "Algorithm for fast interaction search in high-dimensional data")
    (description
     "High dimensional interaction search by brute force requires a quadratic
computational cost in the number of variables.  The xyz algorithm provably
finds strong interactions in almost linear time.  For details of the algorithm
see: G. Thanei, N. Meinshausen and R. Shah (2016).  The xyz algorithm for fast
interaction search in high-dimensional data.")
    ;; Any version of the GPL.
    (license license:gpl2+)))

(define-public r-rttf2pt1
  (package
    (name "r-rttf2pt1")
    (version "1.3.8")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "Rttf2pt1" version))
       (sha256
        (base32
         "0b3f2zkmbyshn19cnaaf042d0zwf43l9jnkqizfhxxwb93a4c1jn"))))
    (properties `((upstream-name . "Rttf2pt1")))
    (build-system r-build-system)
    (home-page "https://github.com/wch/Rttf2pt1")
    (synopsis "Font conversion utility")
    (description
     "This package contains the program @code{ttf2pt1}, for use with the
@code{extrafont} package.")
    ;; Most of the files are covered under the Expat license.  Some files are
    ;; covered under BSD-3.  Deviations for individual files are recorded in
    ;; the LICENSE file.
    (license (list license:bsd-3 license:expat
                   (license:non-copyleft "file://LICENSE")))))

(define-public r-extrafontdb
  (package
    (name "r-extrafontdb")
    (version "1.0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "extrafontdb" version))
       (sha256
        (base32
         "115n42hfvv5h4nn4cfkfmkmn968py4lpy8zd0d6w5yylwpzbm8gs"))))
    (build-system r-build-system)
    (home-page "https://github.com/wch/extrafontdb")
    (synopsis "Database for the extrafont package")
    (description
     "This package holds the database for the @code{extrafont} package.")
    (license license:gpl2)))

(define-public r-extrafont
  (package
    (name "r-extrafont")
    (version "0.17")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "extrafont" version))
       (sha256
        (base32
         "0b9k2n9sk23bh45hjgnkxpjyvpdrz1hx7kmxvmb4nhlhm1wpsv9g"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-extrafontdb" ,r-extrafontdb)
       ("r-rttf2pt1" ,r-rttf2pt1)))
    (home-page "https://github.com/wch/extrafont")
    (synopsis "Tools for using fonts in R")
    (description
     "The extrafont package makes it easier to use fonts other than the basic
PostScript fonts that R uses.  Fonts that are imported into extrafont can be
used with PDF or PostScript output files.  There are two hurdles for using
fonts in PDF (or Postscript) output files:

@enumerate
@item Making R aware of the font and the dimensions of the characters.
@item Embedding the fonts in the PDF file so that the PDF can be displayed
  properly on a device that doesn't have the font.  This is usually needed if
  you want to print the PDF file or share it with others.
@end enumerate

The extrafont package makes both of these things easier.")
    (license license:gpl2)))

(define-public r-xkcd
  (package
    (name "r-xkcd")
    (version "0.0.6")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "xkcd" version))
       (sha256
        (base32
         "1z2y0ihn68ppay7xkglhw7djki5654g6z4bbpyy41if57z9q554f"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-extrafont" ,r-extrafont)
       ("r-ggplot2" ,r-ggplot2)
       ("r-hmisc" ,r-hmisc)))
    (home-page "https://cran.r-project.org/web/packages/xkcd/")
    (synopsis "Plot ggplot2 graphics in the XKCD style")
    (description
     "This package provides the means to plot ggplot2 graphs in the style of
the XKCD web comic.")
    (license license:gpl3)))

(define-public r-msigdbr
  (package
    (name "r-msigdbr")
    (version "7.0.1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "msigdbr" version))
       (sha256
        (base32
         "19p8z617m3my8la7n1qgb1s2msf940r372im3q30qkbcx3qxg3sd"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-dplyr" ,r-dplyr)
       ("r-magrittr" ,r-magrittr)
       ("r-rlang" ,r-rlang)
       ("r-tibble" ,r-tibble)))
    (home-page "https://github.com/igordot/msigdbr")
    (synopsis "MSigDB gene sets for multiple organisms")
    (description
     "This package provides the @dfn{Molecular Signatures Database} (MSigDB)
gene sets typically used with the @dfn{Gene Set Enrichment Analysis} (GSEA)
software in a standard R data frame with key-value pairs.  Included are the
original human gene symbols and Entrez IDs as well as the equivalents for
various frequently studied model organisms such as mouse, rat, pig, fly, and
yeast.")
    ;; The package is covered under the Expat license, but the upstream MSigDB
    ;; files are made available under the Creative Commons Attribution 4.0
    ;; International license.
    (license (list license:expat license:cc-by4.0))))

(define-public r-gridgraphics
  (package
    (name "r-gridgraphics")
    (version "0.5-0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "gridGraphics" version))
       (sha256
        (base32
         "0rlyc3xk8kfrfzbfd8n4javq3yxqd7lsfmi4q5n6s61srnrl6c1r"))))
    (properties `((upstream-name . "gridGraphics")))
    (build-system r-build-system)
    (home-page "https://github.com/pmur002/gridgraphics")
    (synopsis "Redraw base graphics using @code{grid} graphics")
    (description
     "This package provides functions to convert a page of plots drawn with
the @code{graphics} package into identical output drawn with the @code{grid}
package.  The result looks like the original @code{graphics}-based plot, but
consists of @code{grid} grobs and viewports that can then be manipulated with
@code{grid} functions (e.g., edit grobs and revisit viewports).")
    (license license:gpl2+)))

(define-public r-farver
  (package
    (name "r-farver")
    (version "2.0.3")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "farver" version))
       (sha256
        (base32
         "1k75v07dsfkjra2gsgxg9s55cw3b46b1nh960kqphq7cg7gr058f"))))
    (build-system r-build-system)
    (home-page "https://github.com/thomasp85/farver")
    (synopsis "Vectorized color conversion and comparison")
    (description
     "The encoding of color can be handled in many different ways, using
different color spaces.  As different color spaces have different uses,
efficient conversion between these representations are important.  This
package provides a set of functions that gives access to very fast color space
conversion and comparisons implemented in C++, and offers 100-fold speed
improvements over the @code{convertColor} function in the @code{grDevices}
package.")
    (license license:expat)))

(define-public r-ggplotify
  (package
    (name "r-ggplotify")
    (version "0.0.5")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "ggplotify" version))
       (sha256
        (base32
         "0pfnp4lrissf21z7867kdm6slr979kchyva8iaf83i1302kscph3"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-ggplot2" ,r-ggplot2)
       ("r-gridgraphics" ,r-gridgraphics)
       ("r-rvcheck" ,r-rvcheck)))
    (native-inputs
     `(("r-knitr" ,r-knitr)))
    (home-page "https://github.com/GuangchuangYu/ggplotify")
    (synopsis "Convert plots to @code{grob} or @code{ggplot} object")
    (description
     "This package provides tools to convert plot function calls (using
expression or formula) to @code{grob} or @code{ggplot} objects that are
compatible with the @code{grid} and @code{ggplot2} environment.  With this
package, we are able to e.g. use @code{cowplot} to align plots produced by
@code{base} graphics, @code{grid}, @code{lattice}, @code{vcd} etc. by
converting them to @code{ggplot} objects.")
    (license license:artistic2.0)))

(define-public r-triebeard
  (package
    (name "r-triebeard")
    (version "0.3.0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "triebeard" version))
       (sha256
        (base32
         "1hqyz57gph02c9fdc07lxz113bbklif3g18sw8jan6pakhhdc7dz"))))
    (build-system r-build-system)
    (propagated-inputs `(("r-rcpp" ,r-rcpp)))
    (home-page "https://github.com/Ironholds/triebeard/")
    (synopsis "Radix trees in Rcpp")
    (description
     "Radix trees, or tries, are key-value data structures optimized for
efficient lookups, similar in purpose to hash tables.  This package provides
an implementation of radix trees for use in R programming and in developing
packages with Rcpp.")
    (license license:expat)))

(define-public r-tweenr
  (package
    (name "r-tweenr")
    (version "1.0.1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "tweenr" version))
       (sha256
        (base32
         "0sq90pbln6lkc2q3zflhkxxwpqdw5dd7igrxhdnlynkdrmi83mpg"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-farver" ,r-farver)
       ("r-magrittr" ,r-magrittr)
       ("r-rcpp" ,r-rcpp)
       ("r-rlang" ,r-rlang)))
    (home-page "https://github.com/thomasp85/tweenr")
    (synopsis "Interpolate data for smooth animations")
    (description
     "In order to create smooth animation between states of data, tweening is
necessary.  This package provides a range of functions for creating tweened
data that can be used as basis for animation.  Furthermore it adds a number of
vectorized interpolaters for common R data types such as numeric, date and
color.")
    (license license:expat)))

(define-public r-polyclip
  (package
    (name "r-polyclip")
    (version "1.10-0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "polyclip" version))
       (sha256
        (base32
         "0jyk4maqiblvj095jd59dr76kbniyli3v3xvy0a72ljszq6vrnkl"))))
    (build-system r-build-system)
    (native-inputs `(("pkg-config" ,pkg-config)))
    (home-page "http://www.angusj.com/delphi/clipper.php")
    (synopsis "Polygon clipping")
    (description
     "This package provides an R port of the library Clipper.  It performs
polygon clipping operations (intersection, union, set minus, set difference)
for polygonal regions of arbitrary complexity, including holes.  It computes
offset polygons (spatial buffer zones, morphological dilations, Minkowski
dilations) for polygonal regions and polygonal lines.  It computes the
Minkowski Sum of general polygons.  There is a function for removing
self-intersections from polygon data.")
    (license license:boost1.0)))

(define-public r-urltools
  (package
    (name "r-urltools")
    (version "1.7.3")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "urltools" version))
       (sha256
        (base32
         "04x3my655dd287cbsszbnf75q0swmjlxxrblcsay7a8n3df3a830"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-rcpp" ,r-rcpp)
       ("r-triebeard" ,r-triebeard)))
    (home-page "https://github.com/Ironholds/urltools/")
    (synopsis "Vectorized tools for URL handling and parsing")
    (description
     "This package provides a toolkit for all URL-handling needs, including
encoding and decoding, parsing, parameter extraction and modification.  All
functions are designed to be both fast and entirely vectorized.  It is
intended to be useful for people dealing with web-related datasets, such as
server-side logs, although may be useful for other situations involving large
sets of URLs.")
    (license license:expat)))

(define-public r-ggforce
  (package
    (name "r-ggforce")
    (version "0.3.1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "ggforce" version))
       (sha256
        (base32
         "04926cqrda6psvy2nzkkw4czwyxdp7fnxg76byp14v12kgd72lm0"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-ggplot2" ,r-ggplot2)
       ("r-gtable" ,r-gtable)
       ("r-mass" ,r-mass)
       ("r-polyclip" ,r-polyclip)
       ("r-rcpp" ,r-rcpp)
       ("r-rcppeigen" ,r-rcppeigen)
       ("r-rlang" ,r-rlang)
       ("r-scales" ,r-scales)
       ("r-tidyselect" ,r-tidyselect)
       ("r-tweenr" ,r-tweenr)
       ("r-withr" ,r-withr)))
    (home-page "https://ggforce.data-imaginist.com")
    (synopsis "Accelerating ggplot2")
    (description
     "The aim of the ggplot2 package is to aid in visual data investigations.
This focus has led to a lack of facilities for composing specialized plots.
Thi package aims to be a collection of mainly new statistics and geometries
that fills this gap.")
    (license license:expat)))

(define-public r-europepmc
  (package
    (name "r-europepmc")
    (version "0.3")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "europepmc" version))
       (sha256
        (base32
         "1ngqs1sqzkbwv98dd5z4cxj8bnz41wyd0g060a2vpqi3s99s4i2h"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-dplyr" ,r-dplyr)
       ("r-httr" ,r-httr)
       ("r-jsonlite" ,r-jsonlite)
       ("r-plyr" ,r-plyr)
       ("r-progress" ,r-progress)
       ("r-purrr" ,r-purrr)
       ("r-urltools" ,r-urltools)
       ("r-xml2" ,r-xml2)))
    (home-page "https://github.com/ropensci/europepmc/")
    (synopsis "R Interface to the Europe PubMed Central RESTful Web Service")
    (description
     "This package provides an R Client for the
@url{https://europepmc.org/RestfulWebService,Europe PubMed Central RESTful Web
Service}.  It gives access to both metadata on life science literature and
open access full texts.  Europe PMC indexes all PubMed content and other
literature sources including Agricola, a bibliographic database of citations
to the agricultural literature, or Biological Patents.  In addition to
bibliographic metadata, the client allows users to fetch citations and
reference lists.  Links between life-science literature and other EBI
databases, including ENA, PDB or ChEMBL are also accessible.")
    (license license:gpl3)))

(define-public r-ggraph
  (package
    (name "r-ggraph")
    (version "2.0.2")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "ggraph" version))
       (sha256
        (base32
         "1ckq82hg52vr2wydkqv2wrppgjyvddd6bwqzrngqlm7j71xapjl0"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-digest" ,r-digest)
       ("r-dplyr" ,r-dplyr)
       ("r-ggforce" ,r-ggforce)
       ("r-ggplot2" ,r-ggplot2)
       ("r-ggrepel" ,r-ggrepel)
       ("r-graphlayouts" ,r-graphlayouts)
       ("r-gtable" ,r-gtable)
       ("r-igraph" ,r-igraph)
       ("r-mass" ,r-mass)
       ("r-rcpp" ,r-rcpp)
       ("r-rlang" ,r-rlang)
       ("r-scales" ,r-scales)
       ("r-tidygraph" ,r-tidygraph)
       ("r-viridis" ,r-viridis)))
    (native-inputs
     `(("r-knitr" ,r-knitr)))
    (home-page "https://cran.r-project.org/web/packages/ggraph/")
    (synopsis "Implementation of grammar of graphics for graphs and networks")
    (description
     "The grammar of graphics as implemented in ggplot2 is a poor fit for
graph and network visualizations due to its reliance on tabular data input.
The ggraph package is an extension of the ggplot2 API tailored to graph
visualizations and provides the same flexible approach to building up plots
layer by layer.")
    (license license:gpl3)))

(define-public r-varselrf
  (package
    (name "r-varselrf")
    (version "0.7-8")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "varSelRF" version))
       (sha256
        (base32
         "0h49rl1j13yfh97rsfsyh9s2c4wajny4rzms2qw77d0cavxqg53i"))))
    (properties `((upstream-name . "varSelRF")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-randomforest" ,r-randomforest)))
    (home-page "https://www.ligarto.org/rdiaz/software/software")
    (synopsis "Variable selection using random forests")
    (description
     "This package provides tools for the variable selection from random
forests using both backwards variable elimination (for the selection of small
sets of non-redundant variables) and selection based on the importance
spectrum (somewhat similar to scree plots; for the selection of large,
potentially highly-correlated variables).  The main applications are in
high-dimensional data (e.g., microarray data, and other genomics and
proteomics applications).")
    (license license:gpl2+)))

(define-public r-pamr
  (package
    (name "r-pamr")
    (version "1.56.1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "pamr" version))
       (sha256
        (base32
         "0ycpgkk23y3zzkb42n2skcyl35ps1n7jmyzfj7pbxr3f6gr2grfh"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-cluster" ,r-cluster)
       ("r-survival" ,r-survival)))
    (native-inputs `(("gfortran" ,gfortran)))
    (home-page "https://cran.r-project.org/web/packages/pamr/")
    (synopsis "Prediction Analysis for Microarrays")
    (description
     "This package provides some functions for sample classification in
microarrays.")
    (license license:gpl2)))

(define-public r-rda
  (package
    (name "r-rda")
    (version "1.0.2-2.1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "rda" version))
       (sha256
        (base32
         "1y4fawslr3i6crjaxhsdb47kfsqkyszdx6avq3r5far5a4pvc639"))))
    (build-system r-build-system)
    (home-page "https://cran.r-project.org/web/packages/rda/")
    (synopsis "Shrunken centroids regularized discriminant analysis")
    (description
     "This package provides tools for shrunken centroids regularized
discriminant analysis for the purpose of classifying high dimensional data.")
    (license license:gpl2+)))

(define-public r-ggvis
  (package
    (name "r-ggvis")
    (version "0.4.5")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "ggvis" version))
       (sha256
        (base32
         "091i9f17912j8qcyxppjgwzjnyqj7769ixs9d2gjg6f2clskqdw2"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-assertthat" ,r-assertthat)
       ("r-dplyr" ,r-dplyr)
       ("r-htmltools" ,r-htmltools)
       ("r-jsonlite" ,r-jsonlite)
       ("r-lazyeval" ,r-lazyeval)
       ("r-magrittr" ,r-magrittr)
       ("r-shiny" ,r-shiny)))
    (home-page "https://ggvis.rstudio.com/")
    (synopsis "Interactive grammar of graphics")
    (description
     "This package is a data visualization package for R providing an
implementation of an interactive grammar of graphics, taking the best parts of
ggplot2, combining them with the reactive framework of Shiny and drawing web
graphics using Vega.")
    (license license:gpl2)))

(define-public r-gbm
  (package
    (name "r-gbm")
    (version "2.1.5")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "gbm" version))
       (sha256
        (base32
         "0vs6ljaqhwwpgr8wlbhmm4v147rd82kl16rpaijqiylxcc8dxyq6"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-gridextra" ,r-gridextra)
       ("r-lattice" ,r-lattice)
       ("r-survival" ,r-survival)))
    (home-page "https://github.com/gbm-developers/gbm")
    (synopsis "Generalized boosted regression models")
    (description
     "This package is an implementation of extensions to Freund and Schapire's
AdaBoost algorithm and Friedman's gradient boosting machine.  It includes
regression methods for least squares, absolute loss, t-distribution loss,
quantile regression, logistic, multinomial logistic, Poisson, Cox proportional
hazards partial likelihood, AdaBoost exponential loss, Huberized hinge loss,
and Learning to Rank measures (LambdaMart).")
    (license license:gpl2+)))

(define-public r-threejs
  (package
    (name "r-threejs")
    (version "0.3.3")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "threejs" version))
       (sha256
        (base32
         "1711h351nzxfkbbdwvfzyhciyvi9c6wx3jq1g97lzcqgnb45kivn"))))
    (build-system r-build-system)
    (arguments
     `(#:modules ((guix build utils)
                  (guix build r-build-system)
                  (srfi srfi-1)
                  (ice-9 popen))
       #:phases
       (modify-phases %standard-phases
         (add-after 'unpack 'process-javascript
           (lambda* (#:key inputs #:allow-other-keys)
             (with-directory-excursion "inst"
               (call-with-values
                   (lambda ()
                     (unzip2
                      `((,(assoc-ref inputs "js-jquery")
                         "htmlwidgets/lib/jquery/jquery.min.js")
                        (,(assoc-ref inputs "js-threejs-111")
                         "htmlwidgets/lib/threejs-111/three.min.js"))))
                 (lambda (sources targets)
                   (for-each (lambda (source target)
                               (format #t "Processing ~a --> ~a~%"
                                       source target)
                               (delete-file target)
                               (let ((minified (open-pipe* OPEN_READ "uglify-js" source)))
                                 (call-with-output-file target
                                   (lambda (port)
                                     (dump-port minified port)))))
                             sources targets))))
             #t)))))
    (propagated-inputs
     `(("r-base64enc" ,r-base64enc)
       ("r-crosstalk" ,r-crosstalk)
       ("r-htmlwidgets" ,r-htmlwidgets)
       ("r-igraph" ,r-igraph)))
    (native-inputs
     `(("uglify-js" ,uglify-js)
       ("js-jquery"
        ,(origin
           (method url-fetch)
           (uri "https://code.jquery.com/jquery-1.12.4.js")
           (sha256
            (base32
             "0x9mrc1668icvhpwzvgafm8xm11x9lfai9nwr66aw6pjnpwkc3s3"))))
       ("js-threejs-111"
        ,(origin
           (method url-fetch)
           (uri "https://raw.githubusercontent.com/mrdoob/three.js/r111/build/three.js")
           (sha256
            (base32
             "1cxdkw3plmlw1xvhbx5dm39gqczgzxip2dm887v6whhsxqxl9cky"))))))
    (home-page "https://bwlewis.github.io/rthreejs")
    (synopsis "Interactive 3D scatter plots, networks and globes")
    (description
     "Create interactive 3D scatter plots, network plots, and globes in R
using the three.js visualization library.")
    (license license:expat)))

(define-public r-mlbench
  (package
    (name "r-mlbench")
    (version "2.1-1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "mlbench" version))
       (sha256
        (base32
         "1rp035qxfgh5ail92zjh9jh57dj0b8babw3wsg29v8ricpal30bl"))))
    (build-system r-build-system)
    (home-page "https://cran.r-project.org/web/packages/mlbench/")
    (synopsis "Machine learning benchmark problems")
    (description
     "This package provides a collection of artificial and real-world machine
learning benchmark problems, including, e.g., several data sets from the UCI
repository.")
    (license license:gpl2)))

(define-public r-mpm
  (package
    (name "r-mpm")
    (version "1.0-22")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "mpm" version))
       (sha256
        (base32
         "0wijw8v0wmbfrda5564cmnp788qmlkk21yn5cp5qk8aprm9l1fnk"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-kernsmooth" ,r-kernsmooth)
       ("r-mass" ,r-mass)))
    (home-page "http://mpm.r-forge.r-project.org")
    (synopsis "Multivariate projection methods")
    (description
     "This is a package for exploratory graphical analysis of multivariate
data, specifically gene expression data with different projection methods:
principal component analysis, correspondence analysis, spectral map
analysis.")
    (license license:gpl2+)))

(define-public r-png
  (package
    (name "r-png")
    (version "0.1-7")
    (source (origin
              (method url-fetch)
              (uri (cran-uri "png" version))
              (sha256
               (base32
                "0g2mcp55lvvpx4kd3mn225mpbxqcq73wy5qx8b4lyf04iybgysg2"))))
    (build-system r-build-system)
    (inputs
     `(("libpng" ,libpng)
       ("zlib" ,zlib)))
    (home-page "https://www.rforge.net/png/")
    (synopsis "Read and write PNG images")
    (description
     "This package provides an easy and simple way to read, write and display
bitmap images stored in the PNG format.  It can read and write both files and
in-memory raw vectors.")
    ;; Any of these GPL versions.
    (license (list license:gpl2 license:gpl3))))

(define-public r-ggcorrplot
  (package
    (name "r-ggcorrplot")
    (version "0.1.3")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "ggcorrplot" version))
       (sha256
        (base32
         "0hi9lz121ya1l2lbm7rqlxg6fs6bvxck396dngnidrhl5fvqb41b"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-ggplot2" ,r-ggplot2)
       ("r-reshape2" ,r-reshape2)))
    (home-page "http://www.sthda.com/english/wiki/ggcorrplot")
    (synopsis "Visualization of a correlation matrix using ggplot2")
    (description
     "The ggcorrplot package can be used to visualize easily a correlation
matrix using ggplot2.  It provides a solution for reordering the correlation
matrix and displays the significance level on the plot.  It also includes a
function for computing a matrix of correlation p-values.")
    (license license:gpl2)))

(define-public r-flexdashboard
  (package
    (name "r-flexdashboard")
    (version "0.5.1.1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "flexdashboard" version))
       (sha256
        (base32
         "0fy3nbrr67zqgd44r2mc850s5sp0hzfcw3zqs15m8kxzj1aw067x"))))
    (build-system r-build-system)
    (arguments
     `(#:modules ((guix build utils)
                  (guix build r-build-system)
                  (srfi srfi-1)
                  (srfi srfi-26)
                  (ice-9 popen)
                  (ice-9 textual-ports))
       #:phases
       (modify-phases %standard-phases
         (add-after 'unpack 'process-javascript
           (lambda* (#:key inputs #:allow-other-keys)
             (with-directory-excursion "inst"
               ;; Concatenate all components of prism.js
               (let ((contents (string-join
                                (map (lambda (name)
                                       (call-with-input-file
                                           (assoc-ref inputs name)
                                         get-string-all))
                                     (list "js-prism"
                                           "js-prism-r"
                                           "js-prism-line-numbers"))
                                "\n")))
                 (call-with-output-file "prism-src.js"
                   (cut display contents <>)))
               (call-with-values
                   (lambda ()
                     (unzip2
                      `(("www/stickytableheaders/jquery.stickytableheaders.js"
                         "www/stickytableheaders/jquery.stickytableheaders.min.js")
                        ("www/sly/sly.js"
                         "www/sly/sly.min.js")
                        ("prism-src.js"
                         "www/prism/prism.js")
                        (,(assoc-ref inputs "js-raphael")
                         "htmlwidgets/lib/raphael/raphael-2.1.4.min.js")
                        (,(assoc-ref inputs "js-featherlight")
                         "www/featherlight/featherlight.min.js"))))
                 (lambda (sources targets)
                   (for-each (lambda (source target)
                               (format #t "Processing ~a --> ~a~%"
                                       source target)
                               (delete-file target)
                               (let ((minified (open-pipe* OPEN_READ "uglify-js" source)))
                                 (call-with-output-file target
                                   (lambda (port)
                                     (dump-port minified port)))))
                             sources targets))))
             #t)))))
    (propagated-inputs
     `(("r-htmltools" ,r-htmltools)
       ("r-htmlwidgets" ,r-htmlwidgets)
       ("r-jsonlite" ,r-jsonlite)
       ("r-knitr" ,r-knitr)
       ("r-rmarkdown" ,r-rmarkdown)
       ("r-shiny" ,r-shiny)))
    (native-inputs
     `(("uglify-js" ,uglify-js)
       ("js-raphael"
        ,(origin
           (method url-fetch)
           (uri "https://raw.githubusercontent.com/DmitryBaranovskiy/raphael/v2.1.4/raphael.js")
           (sha256
            (base32
             "1h4c4akrgcj7wra9j1z1rv2406j0yf68y9c0wg8v7w9ibw2iwf1x"))))
       ("js-prism"
        ,(origin
           (method url-fetch)
           (uri "https://raw.githubusercontent.com/PrismJS/prism/v1.16.0/prism.js")
           (sha256
            (base32
             "0gqa9irbp9k8p5r3d98cszajzhjnssnl43nrsc5aiy7ki52z500c"))))
       ("js-prism-r"
        ,(origin
           (method url-fetch)
           (uri "https://raw.githubusercontent.com/PrismJS/prism/v1.16.0/components/prism-r.js")
           (sha256
            (base32
             "1x31glci7wdgr2305njy0bm2lncb0jyn0j1s2g72rqi29xid9aki"))))
       ("js-prism-line-numbers"
        ,(origin
           (method url-fetch)
           (uri "https://raw.githubusercontent.com/PrismJS/prism/v1.16.0/plugins/line-numbers/prism-line-numbers.js")
           (sha256
            (base32
             "1543wgf3iynrilyb27jq8px3h5gvfz5xmdib5ik2ki400c1sl991"))))
       ("js-featherlight"
        ,(origin
           (method url-fetch)
           (uri "https://raw.githubusercontent.com/noelboss/featherlight/1.3.4/src/featherlight.js")
           (sha256
            (base32
             "14kkhwzvp8rxq2mrck5i0xcm8v5rqwqhwnmncbng8h4qq42zx3sb"))))))
    (home-page "https://rmarkdown.rstudio.com/flexdashboard")
    (synopsis "R Markdown format for flexible dashboards")
    (description
     "This package provides an R Markdown format for converting an R Markdown
document to a grid-oriented dashboard.  The dashboard flexibly adapts the size
of its components to the containing web page.")
    (license license:expat)))

(define-public r-preseqr
  (package
    (name "r-preseqr")
    (version "4.0.0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "preseqR" version))
       (sha256
        (base32
         "1g2rnnmi45649vpy6z45v5i3wxm54s138ajqrzwi3a5r7x3xnhq1"))))
    (properties `((upstream-name . "preseqR")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-polynom" ,r-polynom)))
    (home-page "https://cran.r-project.org/web/packages/preseqR/")
    (synopsis "Predicting species accumulation curves")
    (description
     "This package can be used to predict the r-species accumulation
curve (r-SAC), which is the number of species represented at least r times as
a function of the sampling effort.  When r = 1, the curve is known as the
species accumulation curve, or the library complexity curve in high-throughput
genomic sequencing.  The package includes both parametric and nonparametric
methods, as described by Deng C, et al. (2018).")
    (license license:gpl3)))

(define-public r-mapplots
  (package
    (name "r-mapplots")
    (version "1.5.1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "mapplots" version))
       (sha256
        (base32
         "18s2y66f8vi8g2r8a25zbgp2xm079r8v8qxv0w71h8krycs6vs9p"))))
    (build-system r-build-system)
    (home-page "https://cran.r-project.org/web/packages/mapplots/")
    (synopsis "Data visualization on maps")
    (description
     "This package helps you create simple maps; add sub-plots like pie plots
to a map or any other plot; format, plot and export gridded data.  The package
was developed for displaying fisheries data but most functions can be used for
more generic data visualisation.")
    (license license:gpl2+)))

(define-public r-pmcmr
  (package
    (name "r-pmcmr")
    (version "4.3")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "PMCMR" version))
       (sha256
        (base32
         "09bvdj2h1086r2cgy3myrhlylplxxlliv8nwx09c8kb1vn02i2ij"))))
    (properties `((upstream-name . "PMCMR")))
    (build-system r-build-system)
    (home-page "https://cran.r-project.org/web/packages/PMCMR/")
    (synopsis "Calculate pairwise multiple comparisons of mean rank sums")
    (description
     "This is a deprecated package for calculating pairwise multiple
comparisons of mean rank sums.  This package is superseded by the novel
PMCMRplus package.  The PMCMR package is no longer maintained, but kept for
compatibility of dependent packages for some time.")
    (license license:gpl3+)))

(define-public r-downloader
  (package
    (name "r-downloader")
    (version "0.4")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "downloader" version))
       (sha256
        (base32
         "1axggnsc27zzgr7snf41j3zd1vp3nfpmq4zj4d01axc709dyg40q"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-digest" ,r-digest)))
    (home-page "https://github.com/wch/downloader")
    (synopsis "Download files over HTTP and HTTPS")
    (description
     "This package provides a wrapper for the @code{download.file} function,
making it possible to download files over HTTPS across platforms.  The
@code{RCurl} package provides this functionality (and much more) but has
external dependencies.  This package has is implemented purely in R.")
    (license license:gpl2)))

(define-public r-rex
  (package
    (name "r-rex")
    (version "1.1.2")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "rex" version))
       (sha256
        (base32
         "0alsadgjgass3wr8y5d247j12qqzg454sc84vpskclrkmz778g5x"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-lazyeval" ,r-lazyeval)
       ("r-magrittr" ,r-magrittr)))
    (home-page "https://github.com/kevinushey/rex")
    (synopsis "Friendly regular expressions")
    (description
     "This package provides a friendly interface for the construction of
regular expressions.  Regular expressions are a very powerful feature, however
they are often difficult to interpret.  Rex allows you to build complex
regular expressions from human readable expressions")
    (license license:expat)))

(define-public r-xmlparsedata
  (package
    (name "r-xmlparsedata")
    (version "1.0.3")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "xmlparsedata" version))
       (sha256
        (base32
         "0gjr3l5z5dp276lchr2649as1rkj56d2mlvbr66yg393zzw50lsh"))))
    (properties `((upstream-name . "xmlparsedata")))
    (build-system r-build-system)
    (home-page "https://github.com/r-lib/xmlparsedata#readme")
    (synopsis "Parse data of @code{R} code as an @code{XML} tree")
    (description
     "This package provides tools to convert the output of
@code{utils::getParseData()} to an @code{XML} tree, that one can search via
@code{XPath}, and is easier to manipulate in general.")
    (license license:expat)))

(define-public r-cyclocomp
  (package
    (name "r-cyclocomp")
    (version "1.1.0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "cyclocomp" version))
       (sha256
        (base32
         "0gky3svk02wiajw7nfjh30684h3qxili4bvsab0m7b6cggw6bgyd"))))
    (properties `((upstream-name . "cyclocomp")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-callr" ,r-callr)
       ("r-crayon" ,r-crayon)
       ("r-desc" ,r-desc)
       ("r-remotes" ,r-remotes)
       ("r-withr" ,r-withr)))
    (home-page "https://github.com/MangoTheCat/cyclocomp")
    (synopsis "Cyclomatic complexity of R code")
    (description
     "Cyclomatic complexity is a software metric, used to indicate the
complexity of a program.  It is a quantitative measure of the number of
linearly independent paths through a program's source code.  This package
provides tools to compute this metric.")
    (license license:expat)))

(define-public r-lintr
  (package
    (name "r-lintr")
    (version "2.0.1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "lintr" version))
       (sha256
        (base32
         "14yfh641afg6griaadbdciyr3k94fl55s055qwzghgk5gdsj61zy"))))
    (properties `((upstream-name . "lintr")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-codetools" ,r-codetools)
       ("r-crayon" ,r-crayon)
       ("r-cyclocomp" ,r-cyclocomp)
       ("r-digest" ,r-digest)
       ("r-httr" ,r-httr)
       ("r-jsonlite" ,r-jsonlite)
       ("r-knitr" ,r-knitr)
       ("r-rex" ,r-rex)
       ("r-rstudioapi" ,r-rstudioapi)
       ("r-testthat" ,r-testthat)
       ("r-xml2" ,r-xml2)
       ("r-xmlparsedata" ,r-xmlparsedata)))
    (home-page "https://github.com/jimhester/lintr")
    (synopsis "Linter for R code")
    (description "This package checks adherence to a given style, syntax
errors and possible semantic issues.  It supports on the fly checking of R
code edited with @code{RStudio IDE}, @code{Emacs} and @code{Vim}.")
    (license license:expat)))

(define-public r-sctransform
  (package
    (name "r-sctransform")
    (version "0.2.1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "sctransform" version))
       (sha256
        (base32
         "07v3lzccsrkh1glfxd1q20r8f8gl9ls5az0s1dvxm4vcls0hlhyn"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-future-apply" ,r-future-apply)
       ("r-ggplot2" ,r-ggplot2)
       ("r-gridextra" ,r-gridextra)
       ("r-mass" ,r-mass)
       ("r-matrix" ,r-matrix)
       ("r-rcpp" ,r-rcpp)
       ("r-rcppeigen" ,r-rcppeigen)
       ("r-reshape2" ,r-reshape2)))
    (home-page "https://github.com/ChristophH/sctransform")
    (synopsis "Variance stabilizing transformations for Single Cell UMI Data")
    (description
     "This package provides a normalization method for single-cell UMI count
data using a variance stabilizing transformation.  The transformation is based
on a negative binomial regression model with regularized parameters.  As part
of the same regression framework, this package also provides functions for
batch correction, and data correction.")
    (license license:gpl3)))

(define-public r-styler
  (package
    (name "r-styler")
    (version "1.3.2")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "styler" version))
       (sha256
        (base32
         "1waglhsy2c53qjgd2qhlzda3z0lbzbwx9fkrfhac41y6h91mgkrz"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-backports" ,r-backports)
       ("r-cli" ,r-cli)
       ("r-magrittr" ,r-magrittr)
       ("r-purrr" ,r-purrr)
       ("r-r-cache" ,r-r-cache)
       ("r-rematch2" ,r-rematch2)
       ("r-rlang" ,r-rlang)
       ("r-rprojroot" ,r-rprojroot)
       ("r-tibble" ,r-tibble)
       ("r-withr" ,r-withr)
       ("r-xfun" ,r-xfun)))
    (home-page "https://github.com/r-lib/styler")
    (synopsis "Non-invasive pretty printing of R code")
    (description
     "This is a package for pretty-printing R code without changing the user's
formatting intent.")
    (license license:gpl3)))

(define-public r-scrime
  (package
    (name "r-scrime")
    (version "1.3.5")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "scrime" version))
       (sha256
        (base32
         "0y2mh9fsffjf3i15bafpasa17z99c1s75r8g6h4hgcwfgpjx75sx"))))
    (build-system r-build-system)
    (home-page "https://cran.r-project.org/web/packages/scrime/")
    (synopsis "Analysis of high-dimensional categorical data such as SNP data")
    (description
     "This package provides tools for the analysis of high-dimensional data
developed/implemented at the group \"Statistical Complexity Reduction In
Molecular Epidemiology\" (SCRIME).  The main focus is on SNP data, but most of
the functions can also be applied to other types of categorical data.")
    (license license:gpl2)))

(define-public r-pbmcapply
  (package
    (name "r-pbmcapply")
    (version "1.5.0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "pbmcapply" version))
       (sha256
        (base32
         "0i58gcqpnbyvc448qfgm45b7rpbmrnagsvk1h1hsqchbbicfslnz"))))
    (build-system r-build-system)
    (home-page "https://github.com/kvnkuang/pbmcapply")
    (synopsis "Track the progress of apply procedures with a progress bar")
    (description
     "This light-weight package helps you track and visualize the progress of
parallel versions of vectorized R functions of the @code{mc*apply} family.")
    (license license:expat)))

(define-public r-blme
  (package
    (name "r-blme")
    (version "1.0-4")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "blme" version))
       (sha256
        (base32
         "1ca2b0248k0fj3lczn9shfjplz1sl4ay4v6djldizp2ch2vwdgy2"))))
    (build-system r-build-system)
    (propagated-inputs `(("r-lme4" ,r-lme4)))
    (home-page "https://github.com/vdorie/blme")
    (synopsis "Bayesian linear mixed-effects models")
    (description
     "This package provides tools for maximum a posteriori estimation for
linear and generalized linear mixed-effects models in a Bayesian setting.  It
extends the lme4 package.")
    (license license:gpl2+)))

(define-public r-batchtools
  (package
    (name "r-batchtools")
    (version "0.9.13")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "batchtools" version))
       (sha256
        (base32
         "02bwfinwgn5nl638997javig61jmr0ci0qybmprz13jnvmam1yns"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-backports" ,r-backports)
       ("r-base64url" ,r-base64url)
       ("r-brew" ,r-brew)
       ("r-checkmate" ,r-checkmate)
       ("r-data-table" ,r-data-table)
       ("r-digest" ,r-digest)
       ("r-fs" ,r-fs)
       ("r-progress" ,r-progress)
       ("r-r6" ,r-r6)
       ("r-rappdirs" ,r-rappdirs)
       ("r-stringi" ,r-stringi)
       ("r-withr" ,r-withr)))
    (native-inputs
     `(("r-knitr" ,r-knitr)))
    (home-page "https://github.com/mllg/batchtools")
    (synopsis "Tools for computation on batch systems")
    (description
     "As a successor of the packages BatchJobs and BatchExperiments, this
package provides a parallel implementation of the Map function for high
performance computing systems managed by various schedulers.  A multicore and
socket mode allow the parallelization on a local machines, and multiple
machines can be hooked up via SSH to create a makeshift cluster.  Moreover,
the package provides an abstraction mechanism to define large-scale computer
experiments in a well-organized and reproducible way.")
    (license license:lgpl3)))

(define-public r-clue
  (package
    (name "r-clue")
    (version "0.3-57")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "clue" version))
       (sha256
        (base32
         "05rdcahawxlxci3fjxihjvvh33wqpxw50sx015165ab4nh3rsdkf"))))
    (build-system r-build-system)
    (propagated-inputs `(("r-cluster" ,r-cluster)))
    (home-page "https://cran.r-project.org/web/packages/clue/")
    (synopsis "Tools for analyzing cluster ensembles")
    (description "Cluster ensembles are collections of individual solutions to
a given clustering problem which are useful or necessary to consider in a wide
range of applications.  This R package provides an extensible computational
environment for creating and analyzing cluster ensembles, with basic data
structures for representing partitions and hierarchies, and facilities for
computing on them, including methods for measuring proximity and obtaining
consensus and secondary clusterings.")
    (license license:gpl2)))

(define-public r-sitmo
  (package
    (name "r-sitmo")
    (version "2.0.1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "sitmo" version))
       (sha256
        (base32
         "0apdhwy3kxs39agsbvx5vn3xsgb22bf3jrwmr2cmqk9kmxbx740c"))))
    (build-system r-build-system)
    (propagated-inputs `(("r-rcpp" ,r-rcpp)))
    (home-page "https://github.com/coatless/sitmo/")
    (synopsis "Parallel pseudo random number generator header files")
    (description
     "This package provides two high quality and fast PPRNGs that may be used
in an OpenMP parallel environment.  In addition, there is a generator for one
dimensional low-discrepancy sequence.")
    (license license:expat)))

(define-public r-dqrng
  (package
    (name "r-dqrng")
    (version "0.2.1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "dqrng" version))
       (sha256
        (base32
         "0rp8q5zijlvaqmpnkwr314w9w40sj4fz7sqsdgsffcfvn42w2jg1"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-bh" ,r-bh)
       ("r-rcpp" ,r-rcpp)
       ("r-sitmo" ,r-sitmo)))
    (home-page "https://www.daqana.org/dqrng")
    (synopsis "Fast pseudo random number generators")
    (description
     "Several fast random number generators are provided as C++ header-only
libraries: the PCG family as well as Xoroshiro128+ and Xoshiro256+.
Additionally, fast functions for generating random numbers according to a
uniform, normal and exponential distribution are included.  The latter two use
the Ziggurat algorithm originally proposed by Marsaglia and Tsang.  These
functions are exported to R and as a C++ interface and are enabled for use
with the default 64 bit generator from the PCG family, Xoroshiro128+ and
Xoshiro256+ as well as the 64 bit version of the 20 rounds Threefry
engine (Salmon et al., 2011) as provided by the package @code{sitmo}.")
    ;; This package includes code under CC0 and Apache 2.0 or Expat, but as a
    ;; whole is distributed under the terms of the AGPL 3.
    (license license:agpl3)))

(define-public r-dalex
  (package
    (name "r-dalex")
    (version "1.0.1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "DALEX" version))
       (sha256
        (base32
         "1jbyn57vn6d281a5y15h5d8ljin8cdb9lr7lbgggc950blyfv4g0"))))
    (properties `((upstream-name . "DALEX")))
    (build-system r-build-system)
    (propagated-inputs `(("r-ggplot2" ,r-ggplot2)))
    (home-page "https://pbiecek.github.io/DALEX/")
    (synopsis "Descriptive machine learning explanations")
    (description
     "Machine Learning models are widely used and have various applications in
classification or regression.  Models created with boosting, bagging, stacking
or similar techniques are often used due to their high performance, but such
black-box models usually lack interpretability.  The DALEX package contains
various explainers that help to understand the link between input variables
and model output.")
    ;; Any version of the GPL
    (license license:gpl3+)))

(define-public r-enrichr
  (package
    (name "r-enrichr")
    (version "2.1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "enrichR" version))
       (sha256
        (base32
         "0ymhzs9d2wl0s9rvbqc1hqb78mlzwhlc7mmijpfqkm5r720pf6m1"))))
    (properties `((upstream-name . "enrichR")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-httr" ,r-httr)
       ("r-rjson" ,r-rjson)))
    (home-page "https://cran.r-project.org/web/packages/enrichR/")
    (synopsis "R Interface to Enrichr database for analyzing gene sets")
    (description
     "This package provides an R interface to all Enrichr databases, a
web-based tool for analyzing gene sets and returns any enrichment of common
annotated biological functions.")
    (license license:gpl2+)))

(define-public r-plot3d
  (package
    (name "r-plot3d")
    (version "1.3")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "plot3D" version))
       (sha256
        (base32
         "1jfzndnlci9a975qbcv66jiy2l46hs3f2049654x4jp3i4kyrr5r"))))
    (properties `((upstream-name . "plot3D")))
    (build-system r-build-system)
    (propagated-inputs `(("r-misc3d" ,r-misc3d)))
    (home-page "https://cran.r-project.org/web/packages/plot3D")
    (synopsis "Plot multi-dimensional data")
    (description
     "This package provides functions for viewing 2D and 3D data, including
perspective plots, slice plots, surface plots, scatter plots, etc.  It
includes data sets from oceanography.")
    (license license:gpl3+)))

(define-public r-ggfortify
  (package
    (name "r-ggfortify")
    (version "0.4.9")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "ggfortify" version))
       (sha256
        (base32
         "1p6knrbyaynaqwd939w09hpf1zz1gn95cb46sfgppl8l98krb2h5"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-dplyr" ,r-dplyr)
       ("r-ggplot2" ,r-ggplot2)
       ("r-gridextra" ,r-gridextra)
       ("r-scales" ,r-scales)
       ("r-stringr" ,r-stringr)
       ("r-tibble" ,r-tibble)
       ("r-tidyr" ,r-tidyr)))
    (native-inputs
     `(("r-knitr" ,r-knitr)))
    (home-page "https://github.com/sinhrks/ggfortify")
    (synopsis "Data visualization tools for statistical analysis results")
    (description
     "This package provides unified plotting tools for statistics commonly
used, such as GLM, time series, PCA families, clustering and survival
analysis.  The package offers a single plotting interface for these analysis
results and plots in a unified style using the @code{ggplot2} package.")
    (license license:gpl2)))

(define-public r-refmanager
  (package
    (name "r-refmanager")
    (version "1.2.12")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "RefManageR" version))
       (sha256
        (base32
         "1hfxa1qacfryk36mpaqdhdgws5jwxiyy489ikd3wa18bp1wz8dkp"))))
    (properties `((upstream-name . "RefManageR")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-bibtex" ,r-bibtex)
       ("r-httr" ,r-httr)
       ("r-jsonlite" ,r-jsonlite)
       ("r-lubridate" ,r-lubridate)
       ("r-plyr" ,r-plyr)
       ("r-stringr" ,r-stringr)
       ("r-xml2" ,r-xml2)))
    (home-page "https://github.com/ropensci/RefManageR/")
    (synopsis "Straightforward BibTeX and BibLaTeX bibliography management")
    (description
     "This package provides tools for importing and working with bibliographic
references.  It greatly enhances the @code{bibentry} class by providing a
class @code{BibEntry} which stores BibTeX and BibLaTeX references, supports
UTF-8 encoding, and can be easily searched by any field, by date ranges, and
by various formats for name lists (author by last names, translator by full
names, etc.).  Entries can be updated, combined, sorted, printed in a number
of styles, and exported.  BibTeX and BibLaTeX @code{.bib} files can be read
into R and converted to @code{BibEntry} objects.")
    ;; Any of these licenses may be picked.
    (license (list license:gpl2 license:gpl3 license:bsd-3))))

(define-public r-citr
  (package
    (name "r-citr")
    (version "0.3.2")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "citr" version))
       (sha256
        (base32
         "1qbarvafjb8jgkrnrhh6jw7mcglmjwf7dpdiibxf39jkmlhf7las"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-assertthat" ,r-assertthat)
       ("r-curl" ,r-curl)
       ("r-httr" ,r-httr)
       ("r-miniui" ,r-miniui)
       ("r-refmanager" ,r-refmanager)
       ("r-rstudioapi" ,r-rstudioapi)
       ("r-shiny" ,r-shiny)
       ("r-shinyjs" ,r-shinyjs)
       ("r-yaml" ,r-yaml)))
    (home-page "https://github.com/crsh/citr")
    (synopsis "RStudio add-in to insert Markdown citations")
    (description
     "This package provides functions and an RStudio add-in that search a
BibTeX or BibLaTeX file to create and insert formatted Markdown citations into
the current document.")
    (license license:expat)))

(define-public r-xgboost
  (package
    (name "r-xgboost")
    (version "1.0.0.2")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "xgboost" version))
       (sha256
        (base32
         "1ld2w51c5fy3bl0kvjn1iplffc4lmin9s9zz5xx7xsm44d6j6kzd"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-data-table" ,r-data-table)
       ("r-magrittr" ,r-magrittr)
       ("r-matrix" ,r-matrix)
       ("r-stringi" ,r-stringi)))
    (native-inputs
     `(("r-knitr" ,r-knitr)))
    (home-page "https://github.com/dmlc/xgboost")
    (synopsis "Extreme gradient boosting")
    (description
     "This package provides an R interface to Extreme Gradient Boosting, which
is an efficient implementation of the gradient boosting framework from Chen
and Guestrin (2016).  The package includes efficient linear model solver and
tree learning algorithms.  The package can automatically do parallel
computation on a single machine.  It supports various objective functions,
including regression, classification and ranking.  The package is made to be
extensible, so that users are also allowed to define their own objectives
easily.")
    (license license:asl2.0)))

(define-public r-umap
  (package
    (name "r-umap")
    (version "0.2.5.0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "umap" version))
       (sha256
        (base32
         "0qp8zbh6fn8kn6q2h2lyjgmq3pr6gqwsd8ymqx25px13zjhxch9d"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-openssl" ,r-openssl)
       ("r-rcpp" ,r-rcpp)
       ("r-reticulate" ,r-reticulate)
       ("r-rspectra" ,r-rspectra)))
    (native-inputs
     `(("r-knitr" ,r-knitr)))
    (home-page "https://github.com/tkonopka/umap")
    (synopsis "Uniform manifold approximation and projection")
    (description
     "Uniform manifold approximation and projection is a technique for
dimension reduction.  This package provides an interface to the UMAP algorithm
in R, including a translation of the original algorithm into R.")
    (license license:expat)))

(define-public r-uwot
  (package
    (name "r-uwot")
    (version "0.1.8")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "uwot" version))
       (sha256
        (base32
         "1jzh8r1h6f7pw7pb1fr32vn6ai9g10s56ahkq0vi77iznihy1rpd"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-dqrng" ,r-dqrng)
       ("r-fnn" ,r-fnn)
       ("r-irlba" ,r-irlba)
       ("r-matrix" ,r-matrix)
       ("r-rcpp" ,r-rcpp)
       ("r-rcppannoy" ,r-rcppannoy)
       ("r-rcppprogress" ,r-rcppprogress)
       ("r-rspectra" ,r-rspectra)))
    (home-page "https://github.com/jlmelville/uwot")
    (synopsis "Uniform manifold approximation and projection")
    (description
     "This package provides an implementation of the Uniform Manifold
Approximation and Projection dimensionality reduction by McInnes et
al. (2018).  It also provides means to transform new data and to carry out
supervised dimensionality reduction.  An implementation of the related
LargeVis method of Tang et al. (2016) is also provided.")
    (license license:gpl3)))

(define-public r-kableextra
  (package
    (name "r-kableextra")
    (version "1.1.0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "kableExtra" version))
       (sha256
        (base32
         "1nicvw06xsf3a1f5c10mih07b76m2v5s5h165vmz0qx6n1a3492i"))))
    (properties `((upstream-name . "kableExtra")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-digest" ,r-digest)
       ("r-glue" ,r-glue)
       ("r-htmltools" ,r-htmltools)
       ("r-knitr" ,r-knitr)
       ("r-magrittr" ,r-magrittr)
       ("r-readr" ,r-readr)
       ("r-rmarkdown" ,r-rmarkdown)
       ("r-rstudioapi" ,r-rstudioapi)
       ("r-rvest" ,r-rvest)
       ("r-scales" ,r-scales)
       ("r-stringr" ,r-stringr)
       ("r-viridislite" ,r-viridislite)
       ("r-webshot" ,r-webshot)
       ("r-xml2" ,r-xml2)))
    (home-page "https://haozhu233.github.io/kableExtra/")
    (synopsis "Construct complex tables with pipe syntax")
    (description
     "Build complex HTML or LaTeX tables using @code{kable()} from
@code{knitr} and the piping syntax from @code{magrittr}.  The function
@code{kable()} is a light weight table generator coming from @code{knitr}.
This package simplifies the way to manipulate the HTML or LaTeX codes
generated by @code{kable()} and allows users to construct complex tables and
customize styles using a readable syntax.")
    (license license:expat)))

(define-public r-glasso
  (package
    (name "r-glasso")
    (version "1.11")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "glasso" version))
       (sha256
        (base32 "02p3612rpydk195n2qr77lp1j2w8zsw1ckkk98c8angm4r5q8dsc"))))
    (build-system r-build-system)
    (native-inputs `(("gfortran" ,gfortran)))
    (home-page "https://statweb.stanford.edu/~tibs/glasso/")
    (synopsis "Graphical Lasso: estimation of Gaussian graphical models")
    (description
     "This is a package for estimation of a sparse inverse covariance matrix
using a lasso (L1) penalty.  Facilities are provided for estimates along a
path of values for the regularization parameter.")
    (license license:gpl2)))

(define-public r-rhpcblasctl
  (package
    (name "r-rhpcblasctl")
    (version "0.20-17")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "RhpcBLASctl" version))
       (sha256
        (base32
         "0iwc06blr5sx7rylwczi2jrha8sk8qs0jklflwpidl0zj1jxdggp"))))
    (properties `((upstream-name . "RhpcBLASctl")))
    (build-system r-build-system)
    (home-page "https://prs.ism.ac.jp/~nakama/Rhpc/")
    (synopsis "Control the number of threads on BLAS")
    (description
     "This package allows you to control the number of threads the BLAS
library uses.  It is also possible to control the number of threads in
OpenMP.")
    (license license:agpl3+)))

(define-public r-lda
  (package
    (name "r-lda")
    (version "1.4.2")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "lda" version))
       (sha256
        (base32
         "03r4h5kgr8mfy44p66mfj5bp4k00g8zh4a1mhn46jw14pkhs21jn"))))
    (build-system r-build-system)
    (home-page "https://cran.r-project.org/web/packages/lda/")
    (synopsis "Collapsed Gibbs sampling methods for topic models")
    (description
     "This package implements @dfn{latent Dirichlet allocation} (LDA) and
related models.  This includes (but is not limited to) sLDA, corrLDA, and the
mixed-membership stochastic blockmodel.  Inference for all of these models is
implemented via a fast collapsed Gibbs sampler written in C.  Utility
functions for reading/writing data typically used in topic models, as well as
tools for examining posterior distributions are also included.")
    ;; Any version of the LGPL
    (license license:lgpl3+)))

(define-public r-rann-l1
  (package
    (name "r-rann-l1")
    (version "2.5.2")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "RANN.L1" version))
       (sha256
        (base32
         "1hanh3my84mdr5wy6b89fawqzfc184vff1y65wy4l5ld9qza1n44"))))
    (properties `((upstream-name . "RANN.L1")))
    (build-system r-build-system)
    (home-page "https://github.com/jefferis/RANN/tree/master-L1")
    (synopsis "Fast nearest neighbour search using L1 metric")
    (description
     "This package provides tools to find the k nearest neighbours for every
point in a given dataset in O(N log N) time using Arya and Mount's ANN
library.  There is support for approximate as well as exact searches, fixed
radius searches and @code{bd} as well as @code{kd} trees.  The distance is
computed using the L1 (Manhattan, taxicab) metric.")
    (license license:gpl3+)))

(define-public r-leiden
  (package
    (name "r-leiden")
    (version "0.3.3")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "leiden" version))
       (sha256
        (base32
         "1hh6bmbz6cpqwl4i94gxylgv9x92zbqdg81r8r4ymfy8c70f3df2"))))
    (properties `((upstream-name . "leiden")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-igraph" ,r-igraph)
       ("r-matrix" ,r-matrix)
       ("r-reticulate" ,r-reticulate)))
    (home-page "https://github.com/TomKellyGenetics/leiden")
    (synopsis "R implementation of Leiden clustering algorithm")
    (description
     "This package implements the Python @code{leidenalg} module to be called
in R.  It enables clustering using the Leiden algorithm for partitioning a
graph into communities.  See also Traag et al (2018) \"From Louvain to Leiden:
guaranteeing well-connected communities.\" <arXiv:1810.08473>.")
    (license license:gpl3)))

(define-public r-patchwork
  (package
    (name "r-patchwork")
    (version "1.0.0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "patchwork" version))
       (sha256
        (base32
         "0qrwbcswh7ylrmghi17k6wk7w51cz6mcmvcyyd41hy3m2ywmkywb"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-ggplot2" ,r-ggplot2)
       ("r-gtable" ,r-gtable)))
    (native-inputs
     `(("r-knitr" ,r-knitr)))
    (home-page "https://github.com/thomasp85/patchwork")
    (synopsis "Compose ggplot2 plots")
    (description
     "The @code{ggplot2} package provides a strong API for sequentially
building up a plot, but does not concern itself with composition of multiple
plots.  Patchwork is a package that expands the API to allow for arbitrarily
complex composition of plots by providing mathmatical operators for combining
multiple plots.")
    (license license:expat)))

(define-public r-liger
  (package
    (name "r-liger")
    (version "0.4.2")
    (source
     (origin
       (method git-fetch)
       (uri (git-reference
             (url "https://github.com/MacoskoLab/liger.git")
             (commit (string-append "v" version))))
       (file-name (git-file-name name version))
       (sha256
        (base32
         "16dzwwcpw6n78pxlc5w3kraigki35ix7zhd2cbx5f3y60bbkhlmx"))
       (modules '((guix build utils)))
       (snippet
        '(begin
           (delete-file "inst/java/ModularityOptimizer.jar")
           #t))))
    (build-system r-build-system)
    (arguments
     `(#:phases
       (modify-phases %standard-phases
         (add-after 'unpack 'build-java-part
           (lambda* (#:key inputs #:allow-other-keys)
             (invoke "unzip" (assoc-ref inputs "optimizer-src"))
             (for-each (lambda (file) (invoke "javac" file))
                       (find-files "." "\\.java$"))
             (apply invoke "jar" "cf" "inst/java/ModularityOptimizer.jar"
                    (find-files "." "\\.class$"))
             #t)))))
    (propagated-inputs
     `(("r-cowplot" ,r-cowplot)
       ("r-dosnow" ,r-dosnow)
       ("r-dplyr" ,r-dplyr)
       ("r-fnn" ,r-fnn)
       ("r-foreach" ,r-foreach)
       ("r-ggplot2" ,r-ggplot2)
       ("r-ggrepel" ,r-ggrepel)
       ("r-hmisc" ,r-hmisc)
       ("r-ica" ,r-ica)
       ("r-irlba" ,r-irlba)
       ("r-matrix" ,r-matrix)
       ("r-mclust" ,r-mclust)
       ("r-patchwork" ,r-patchwork)
       ("r-plyr" ,r-plyr)
       ("r-rann-l1" ,r-rann-l1)
       ("r-rcpp" ,r-rcpp)
       ("r-rcpparmadillo" ,r-rcpparmadillo)
       ("r-riverplot" ,r-riverplot)
       ("r-rtsne" ,r-rtsne)
       ("r-snow" ,r-snow)))
    (native-inputs
     `(("jdk" ,icedtea "jdk")
       ;; See https://github.com/MacoskoLab/liger/issues/96
       ;; The optimizer is released under the Expat license.
       ("optimizer-src"
        ,(origin
           (method url-fetch)
           (uri "http://www.ludowaltman.nl/slm/modularity_optimizer_source.zip")
           (sha256
            (base32
             "01hmm6sapcmldvayknqx2w4cav3qv71mwwkdkwj4qgq6dss09g18"))))
       ("unzip" ,unzip)
       ("r-knitr" ,r-knitr))) ; for vignettes
    (home-page "https://github.com/MacoskoLab/liger")
    (synopsis "Integrate and analyze multiple single-cell datasets")
    (description
     "LIGER is a package for integrating and analyzing multiple single-cell
datasets, developed and maintained by the Macosko lab.  It relies on
integrative non-negative matrix factorization to identify shared and
dataset-specific factors.")
    (license license:gpl3)))

(define-public r-harmony
  (package
    (name "r-harmony")
    (version "0.1")
    (source
     (origin
       (method git-fetch)
       (uri (git-reference
             (url "https://github.com/immunogenomics/harmony")
             (commit version)))
       (file-name (git-file-name name version))
       (sha256
        (base32
         "05r401q09rbr6fqhb9mbd95082cjdi3nag1cv6zn96xkr0f6imq9"))
       (modules '((guix build utils)))
       (snippet
        '(begin
           (for-each delete-file '("config.status" "configure"))
           #t))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-cowplot" ,r-cowplot)
       ("r-dplyr" ,r-dplyr)
       ("r-ggplot2" ,r-ggplot2)
       ("r-irlba" ,r-irlba)
       ("r-matrix" ,r-matrix)
       ("r-rcpp" ,r-rcpp)
       ("r-rcpparmadillo" ,r-rcpparmadillo)
       ("r-rcppprogress" ,r-rcppprogress)
       ("r-rlang" ,r-rlang)
       ("r-tibble" ,r-tibble)
       ("r-tidyr" ,r-tidyr)))
    (native-inputs
     `(("autoconf" ,autoconf)))
    (home-page "https://github.com/immunogenomics/harmony")
    (synopsis "Integration of single cell sequencing data")
    (description
     "This package provides an implementation of the Harmony algorithm for
single cell integration, described in Korsunsky et al
@url{doi.org/10.1101/461954}.  The package includes a standalone Harmony
function and interfaces to external frameworks.")
    (license license:gpl3)))

(define-public r-covr
  (package
    (name "r-covr")
    (version "3.5.0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "covr" version))
       (sha256
        (base32 "1pvr95h7jg9hqq1qq1cccy323pkxldrwafl08151cc410499k4fb"))))
    (properties `((upstream-name . "covr")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-crayon" ,r-crayon)
       ("r-digest" ,r-digest)
       ("r-httr" ,r-httr)
       ("r-jsonlite" ,r-jsonlite)
       ("r-rex" ,r-rex)
       ("r-withr" ,r-withr)
       ("r-yaml" ,r-yaml)))
    (native-inputs
     `(("r-knitr" ,r-knitr))) ; for vignettes
    (home-page "https://github.com/r-lib/covr")
    (synopsis "Test coverage for R packages")
    (description
     "Thisp package enables you to track and report code coverage for your
package and (optionally) upload the results to a coverage service.  Code
coverage is a measure of the amount of code being exercised by a set of tests.
It is an indirect measure of test quality and completeness.  This package is
compatible with any testing methodology or framework and tracks coverage of
both R code and compiled C/C++/FORTRAN code.")
    (license license:gpl3)))

(define-public r-systemfonts
  (package
    (name "r-systemfonts")
    (version "0.1.1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "systemfonts" version))
       (sha256
        (base32
         "0m0ljid683xcam2f14x7k2zv1yx4npac38a3gfv11vhxfbnpgp0z"))))
    (properties `((upstream-name . "systemfonts")))
    (build-system r-build-system)
    (inputs
     `(("fontconfig" ,fontconfig)
       ("freetype" ,freetype)
       ("zlib" ,zlib)))
    (native-inputs
     `(("pkg-config" ,pkg-config)))
    (home-page "https://github.com/r-lib/systemfonts")
    (synopsis "System native font finding")
    (description
     "This package provides system native access to the font catalogue.  As
font handling varies between systems it is difficult to correctly locate
installed fonts across different operating systems.  The 'systemfonts' package
provides bindings to the native libraries for finding font files that can then
be used further by e.g. graphic devices.")
    (license license:expat)))

(define-public r-graphlayouts
  (package
    (name "r-graphlayouts")
    (version "0.6.0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "graphlayouts" version))
       (sha256
        (base32
         "1la016m37kp79zk8p1yx9kaha8y6d4w52w39h0mzv1mfsi6d75w0"))))
    (properties `((upstream-name . "graphlayouts")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-igraph" ,r-igraph)
       ("r-rcpp" ,r-rcpp)
       ("r-rcpparmadillo" ,r-rcpparmadillo)))
    (home-page "https://github.com/schochastics/graphlayouts")
    (synopsis "Additional layout algorithms for network visualizations")
    (description
     "This package provides several layout algorithms to visualize networks
which are not part of the igraph library.  Most are based on the concept of
stress majorization by Gansner et al. (2004)
<doi:10.1007/978-3-540-31843-9_25>.  Some more specific algorithms
emphasize hidden group structures in networks or focus on specific nodes.")
    (license license:expat)))

(define-public r-tidygraph
  (package
    (name "r-tidygraph")
    (version "1.1.2")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "tidygraph" version))
       (sha256
        (base32
         "1zpsarm74afbc7p5dlyb0whc09670qdcddw1ckb25cfc9hfh0hjn"))))
    (properties `((upstream-name . "tidygraph")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-dplyr" ,r-dplyr)
       ("r-igraph" ,r-igraph)
       ("r-magrittr" ,r-magrittr)
       ("r-pillar" ,r-pillar)
       ("r-r6" ,r-r6)
       ("r-rcpp" ,r-rcpp)
       ("r-rlang" ,r-rlang)
       ("r-tibble" ,r-tibble)
       ("r-tidyr" ,r-tidyr)))
    (home-page "https://github.com/thomasp85/tidygraph")
    (synopsis "Tidy API for graph manipulation")
    (description
     "This package provides a graph implementation that can be thought of as
two tidy data frames describing node and edge data respectively.  It provides
an approach to manipulate these two virtual data frames using the API defined
in the @code{dplyr} package, and it also provides tidy interfaces to a lot of
common graph algorithms.")
    (license license:expat)))

(define-public r-soupx
  (let ((commit "a3354be76fb52fd795be6ddf163cf056c05c6cb8")
        (revision "1"))
    (package
      (name "r-soupx")
      (version (git-version "0.3.1" revision commit))
      (source
       (origin
         (method git-fetch)
         (uri (git-reference
               (url "https://github.com/constantAmateur/SoupX")
               (commit commit)))
         (file-name (git-file-name name version))
         (sha256
          (base32
           "1zmlyzrl0fz6l79gn2wswid670p88mm3y292is89sa5p3h7frr99"))))
      (properties `((upstream-name . "SoupX")))
      (build-system r-build-system)
      (propagated-inputs
       `(("r-ggplot2" ,r-ggplot2)
         ("r-matrix" ,r-matrix)
         ("r-seurat" ,r-seurat)))
      (home-page "https://github.com/constantAmateur/SoupX")
      (synopsis "Single cell mRNA Soup eXterminator")
      (description
       "This package provides a package for quantifying, profiling and
removing cell free mRNA contamination (the \"soup\") from droplet based single
cell RNA-seq experiments.")
      (license license:gpl2))))

(define-public r-assertr
  (package
    (name "r-assertr")
    (version "2.7")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "assertr" version))
       (sha256
        (base32
         "1x868pd4dac1c7b1q5390wqh2f6s50km8nqcpim3nxcj2l4qkqdb"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-dplyr" ,r-dplyr)
       ("r-mass" ,r-mass)
       ("r-rlang" ,r-rlang)))
    (native-inputs
     `(("r-knitr" ,r-knitr)))           ; needed for vignette
    (home-page "https://github.com/ropensci/assertr")
    (synopsis "Assertive programming for R analysis pipelines")
    (description
     "This package provides functionality to assert conditions that have to be
met so that errors in data used in analysis pipelines can fail quickly.  It is
similar to @code{stopifnot()} but more powerful, friendly, and easier for use
in pipelines.")
    (license license:expat)))

(define-public r-parameters
  (package
    (name "r-parameters")
    (version "0.6.0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "parameters" version))
       (sha256
        (base32
         "0zin3ikc013hc713n5zs0dbhc3m4nfw1vhc3924z0mrww8r241xn"))))
    (properties `((upstream-name . "parameters")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-bayestestr" ,r-bayestestr)
       ("r-insight" ,r-insight)))
    (native-inputs
     `(("r-knitr" ,r-knitr)))
    (home-page "https://cran.r-project.org/web/packages/parameters")
    (synopsis "Processing of model parameters")
    (description
     "This package provides utilities for processing the parameters of various
statistical models.  Beyond computing p values, CIs, and other indices for a
wide variety of models, this package implements features like standardization
or bootstrapping of parameters and models, feature reduction (feature
extraction and variable selection) as well as conversion between indices of
effect size.")
    (license license:gpl3)))

(define-public r-rgdal
  (package
    (name "r-rgdal")
    (version "1.4-8")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "rgdal" version))
       (sha256
        (base32 "1jd691amf3ghznq5im15gvhl6v6k25klpl75m4ngrqf9xlxaa3as"))))
    (properties `((upstream-name . "rgdal")))
    (build-system r-build-system)
    (inputs
     `(("gdal" ,gdal)
       ("proj.4" ,proj.4)
       ("zlib" ,zlib)))
    (propagated-inputs
     `(("r-sp" ,r-sp)))
    (native-inputs
     `(("pkg-config" ,pkg-config)))
    (home-page "http://rgdal.r-forge.r-project.org")
    (synopsis "Bindings for the Geospatial Data Abstraction Library")
    (description
     "This package provides bindings to the Geospatial Data Abstraction
Library (GDAL) and access to projection/transformation operations from the
PROJ.4 library.")
    (license license:gpl2+)))

(define-public r-insol
  (package
    (name "r-insol")
    (version "1.2.1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "insol" version))
       (sha256
        (base32
         "1d2vqmbp94ff80mfkmq4a8y12r6ryym8hh1568ip9qbn7snc64v1"))))
    (properties `((upstream-name . "insol")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-raster" ,r-raster)))
    (native-inputs
     `(("gfortran" ,gfortran)))
    (home-page "https://meteoexploration.com/R/insol/index.html")
    (synopsis "Tools for calculating solar radiation")
    (description
     "This package provides functions to compute insolation on tilted
surfaces, computes atmospheric transmittance and related parameters such as:
Earth radius vector, declination, sunset and sunrise, daylength, equation of
time, vector in the direction of the sun, vector normal to surface, and some
atmospheric physics.")
    (license license:gpl2+)))

(define-public r-lifecycle
  (package
    (name "r-lifecycle")
    (version "0.2.0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "lifecycle" version))
       (sha256
        (base32
         "0912865c6675fsblrfdk6s568krsj1x8qbk1kipy7m05xs6nwx19"))))
    (properties `((upstream-name . "lifecycle")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-glue" ,r-glue)
       ("r-rlang" ,r-rlang)))
    (native-inputs
     `(("r-knitr" ,r-knitr))) ; for vignettes
    (home-page "https://github.com/r-lib/lifecycle")
    (synopsis "Manage the life cycle of your package functions")
    (description
     "Manage the life cycle of your exported functions with shared
conventions, documentation badges, and non-invasive deprecation warnings.  The
lifecycle package defines four development stages (experimental, maturing,
stable, and questioning) and three deprecation stages (soft-deprecated,
deprecated, and defunct).  It makes it easy to insert badges corresponding to
these stages in your documentation.  Usage of deprecated functions are
signalled with increasing levels of non-invasive verbosity.")
    (license license:gpl3)))

(define-public r-assertable
  (package
    (name "r-assertable")
    (version "0.2.7")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "assertable" version))
       (sha256
        (base32
         "1npks9rcrnchmd0silq6qrvqkmdkp9fwjkyyvvp1lqjclyxk6vkk"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-data-table" ,r-data-table)))
    (home-page "https://cran.r-project.org/web/packages/assertable/")
    (synopsis "Verbose assertions for tabular data (data.frames and data.tables)")
    (description "This package provides simple, flexible assertions on
data.frame or data.table objects with verbose output for vetting.  While other
assertion packages apply towards more general use-cases, @code{assertable} is
tailored towards tabular data.  It includes functions to check variable names
and values, whether the dataset contains all combinations of a given set of
unique identifiers, and whether it is a certain length.  In addition,
@code{assertable} includes utility functions to check the existence of target
files and to efficiently import multiple tabular data files into one
data.table.")
    (license license:gpl3)))

(define-public r-quadprog
  (package
    (name "r-quadprog")
    (version "1.5-8")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "quadprog" version))
       (sha256
        (base32 "1ka9g8zak8sg4y2xbz93dfrldznlk9qpd4pq9z21cdcdn3b8s4i2"))))
    (build-system r-build-system)
    (native-inputs
     `(("gfortran" ,gfortran)))
    (home-page "https://cran.r-project.org/web/packages/quadprog")
    (synopsis "Functions to solve quadratic programming problems")
    (description
     "This package contains routines and documentation for solving quadratic
programming problems.")
    (license license:gpl3+)))

(define-public r-desolve
  (package
    (name "r-desolve")
    (version "1.28")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "deSolve" version))
       (sha256
        (base32 "0jasvdzig0pzhzspmy20089az19r91xjfb9q6h8gj7c4mr6fymac"))))
    (properties `((upstream-name . "deSolve")))
    (build-system r-build-system)
    (native-inputs
     `(("gfortran" ,gfortran)))
    (home-page "https://desolve.r-forge.r-project.org/")
    (synopsis "Solvers for initial value problems of differential equations")
    (description "This package provides functions that solve initial value
problems of a system of first-order @dfn{ordinary differential
equations} (ODE), of @dfn{partial differential equations} (PDE), of
@dfn{differential algebraic equations} (DAE), and of delay differential
equations.  The functions provide an interface to the FORTRAN functions
@code{lsoda}, @code{lsodar}, @code{lsode}, @code{lsodes} of the ODEPACK
collection, to the FORTRAN functions @code{dvode} and @code{daspk} and a
C-implementation of solvers of the Runge-Kutta family with fixed or variable
time steps.  The package contains routines designed for solving ODEs resulting
from 1-D, 2-D and 3-D partial differential equations that have been converted
to ODEs by numerical differencing.")
    (license license:gpl2+)))

(define-public r-pracma
  (package
    (name "r-pracma")
    (version "2.2.9")
    (source (origin
              (method url-fetch)
              (uri (cran-uri "pracma" version))
              (sha256
               (base32 "07mzhzz73wsjjw1q05l024gcd13hwnzsxf873q9dyhw6x3shzshc"))))
    (build-system r-build-system)
    (home-page "https://cran.r-project.org/web/packages/pracma/")
    (synopsis "Practical numerical math functions")
    (description "This package provides functions for numerical analysis and
linear algebra, numerical optimization, differential equations, plus some
special functions.  It uses Matlab function names where appropriate to simplify
porting.")
    (license license:gpl3+)))

(define-public r-subplex
  (package
    (name "r-subplex")
    (version "1.6")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "subplex" version))
       (sha256
        (base32
         "1yfbfjvpbhgky7vihw3f4jl41pxpqb39z4nc045d5z7z48bdl18d"))))
    (build-system r-build-system)
    (native-inputs
     `(("gfortran" ,gfortran)))
    (home-page "https://cran.r-project.org/web/packages/subplex")
    (synopsis "Unconstrained optimization using the subplex algorithm")
    (description
     "This package implements the Subplex optimization algorithm.
It solves unconstrained optimization problems using a simplex method on
subspaces.  The method is well suited for optimizing objective functions that
are noisy or are discontinuous at the solution.")
    (license license:gpl3+)))

(define-public r-txtplot
  (package
    (name "r-txtplot")
    (version "1.0-3")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "txtplot" version))
       (sha256
        (base32
         "1949ab1bzvysdb79g8x1gaknj0ih3d6g63pv9512h5m5l3a6c31h"))))
    (build-system r-build-system)
    (home-page "https://cran.r-project.org/web/packages/txtplot/")
    (synopsis "Text-based plotting")
    (description "This package provides functions to produce rudimentary ASCII
graphics directly in the terminal window.  This package provides a basic
plotting function (and equivalents of curve, density, acf and barplot) as well
as a boxplot function.")
    (license license:lgpl3+)))

(define-public r-bio3d
  (package
    (name "r-bio3d")
    (version "2.4-1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "bio3d" version))
       (sha256
        (base32
         "07rw6c2d95gb5myxh31727j0jrchd0xisa3x89jjmf4zzs3vv7v7"))))
    (properties `((upstream-name . "bio3d")))
    (build-system r-build-system)
    (inputs `(("zlib" ,zlib)))
    (propagated-inputs `(("r-rcpp" ,r-rcpp)))
    (home-page "http://thegrantlab.org/bio3d/")
    (synopsis "Biological structure analysis")
    (description
     "This package provides utilities to process, organize and explore protein
structure, sequence and dynamics data.  Features include the ability to read
and write structure, sequence and dynamic trajectory data, perform sequence
and structure database searches, data summaries, atom selection, alignment,
superposition, rigid core identification, clustering, torsion analysis,
distance matrix analysis, structure and sequence conservation analysis, normal
mode analysis, principal component analysis of heterogeneous structure data,
and correlation network analysis from normal mode and molecular dynamics data.
In addition, various utility functions are provided to enable the statistical
and graphical power of the R environment to work with biological sequence and
structural data.")
    (license license:gpl2+)))

(define-public r-bios2cor
  (package
    (name "r-bios2cor")
    (version "2.1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "Bios2cor" version))
       (sha256
        (base32
         "04wk1cjrrxhpv1kdhd67r1qvjv268xxi0z0r105wy912110z9m6x"))))
    (properties `((upstream-name . "Bios2cor")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-bigmemory" ,r-bigmemory)
       ("r-bio3d" ,r-bio3d)
       ("r-circular" ,r-circular)
       ("r-igraph" ,r-igraph)))
    (home-page "https://cran.r-project.org/web/packages/Bios2cor/")
    (synopsis "From biological sequences and simulations to correlation analysis")
    (description
     "This package provides utilities for computation and analysis of
correlation/covariation in multiple sequence alignments and in side chain
motions during molecular dynamics simulations.  Features include the
computation of correlation/covariation scores using a variety of scoring
functions between either sequence positions in alignments or side chain
dihedral angles in molecular dynamics simulations and utilities to analyze the
correlation/covariation matrix through a variety of tools including network
representation and principal components analysis.  In addition, several
utility functions are based on the R graphical environment to provide friendly
tools for help in data interpretation.")
    (license license:gpl2+)))

;; This package includes minified JavaScript files.  When upgrading please
;; check that there are no new minified JavaScript files.
(define-public r-networkd3
  (package
    (name "r-networkd3")
    (version "0.4")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "networkD3" version))
       (sha256
        (base32
         "02wxki67drppgfka1is1ykg1f2rxf0x0657c0crj7ipfy62jbf1k"))
       (snippet
        '(begin
           (delete-file "inst/htmlwidgets/lib/d3-4.5.0/d3.min.js")
           #t))))
    (properties `((upstream-name . "networkD3")))
    (build-system r-build-system)
    (arguments
     `(#:modules ((guix build utils)
                  (guix build r-build-system)
                  (srfi srfi-1)
                  (ice-9 popen))
       #:phases
       (modify-phases %standard-phases
         (add-after 'unpack 'process-javascript
           (lambda* (#:key inputs #:allow-other-keys)
             (with-directory-excursion "inst/htmlwidgets/lib/"
               (call-with-values
                   (lambda ()
                     (unzip2
                      `((,(assoc-ref inputs "d3.v4.js")
                         "d3-4.5.0/d3.min.js"))))
                 (lambda (sources targets)
                   (for-each (lambda (source target)
                               (format #t "Processing ~a --> ~a~%"
                                       source target)
                               (let ((minified (open-pipe* OPEN_READ "uglify-js" source)))
                                 (call-with-output-file target
                                   (lambda (port)
                                     (dump-port minified port)))))
                             sources targets))))
             #t)))))
    (native-inputs
     `(("uglify-js" ,uglify-js)
       ;; NOTE: Make sure that this version of d3 is still valid when
       ;; upgrading the package.
       ("d3.v4.js"
        ,(origin
           (method url-fetch)
           (uri "https://d3js.org/d3.v4.js")
           (sha256
            (base32
             "0y7byf6kcinfz9ac59jxc4v6kppdazmnyqfav0dm4h550fzfqqlg"))))))
    (propagated-inputs
     `(("r-htmlwidgets" ,r-htmlwidgets)
       ("r-igraph" ,r-igraph)
       ("r-magrittr" ,r-magrittr)))
    (home-page "https://cran.r-project.org/package=networkD3")
    (synopsis "D3 JavaScript network graphs from R")
    (description
     "This package creates D3 JavaScript network, tree, dendrogram, and Sankey
graphs from R.")
    (license license:gpl3+)))

(define-public r-aasea
  (package
    (name "r-aasea")
    (version "1.1.0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "aaSEA" version))
       (sha256
        (base32
         "0him4r8qyp0xssgrmdxjs45yn4d28h5anv4jyxxbbs9phb0m6j3h"))))
    (properties `((upstream-name . "aaSEA")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-bios2cor" ,r-bios2cor)
       ("r-dt" ,r-dt)
       ("r-hmisc" ,r-hmisc)
       ("r-magrittr" ,r-magrittr)
       ("r-networkd3" ,r-networkd3)
       ("r-plotly" ,r-plotly)
       ("r-seqinr" ,r-seqinr)
       ("r-shiny" ,r-shiny)
       ("r-shinydashboard" ,r-shinydashboard)))
    (home-page "https://cran.r-project.org/web/packages/aaSEA/")
    (synopsis "Amino acid substitution effect analyzer")
    (description
     "Given a protein multiple sequence alignment, it is a daunting task to
assess the effects of substitutions along sequence length.  The aaSEA package
is intended to help researchers to rapidly analyze property changes caused by
single, multiple and correlated amino acid substitutions in proteins.")
    (license license:gpl3)))

(define-public r-abacus
  (package
    (name "r-abacus")
    (version "1.0.0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "ABACUS" version))
       (sha256
        (base32
         "0m1dnkwjr1522l9ddbzzx7ayxvli17sbmk6s28adpmzzjwh2kd1i"))))
    (properties `((upstream-name . "ABACUS")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-ggplot2" ,r-ggplot2)
       ("r-shiny" ,r-shiny)))
    (home-page "https://shiny.abdn.ac.uk/Stats/apps/")
    (synopsis "Apps-based activities for communicating and understanding statistics")
    (description
     "This package provides a set of Shiny apps for effective communication
and understanding in statistics.  The current version includes properties of
normal distribution, properties of sampling distribution, one-sample z and t
tests, two samples independent (unpaired) t test and analysis of variance.")
    (license license:gpl3)))

(define-public r-abc-rap
  (package
    (name "r-abc-rap")
    (version "0.9.0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "ABC.RAP" version))
       (sha256
        (base32
         "1kdspln17v0krvahcd55vib4dv5azp60b3r1zf489x10qqbp1mxk"))))
    (properties `((upstream-name . "ABC.RAP")))
    (build-system r-build-system)
    (home-page "https://cran.r-project.org/web/packages/ABC.RAP/")
    (synopsis "Array-based CpG region analysis pipeline")
    (description
     "This package aims to identify candidate genes that are differentially
methylated between cases and controls.  It applies Student's t-test and delta
beta analysis to identify candidate genes containing multiple CpG sites.")
    (license license:gpl3)))

(define-public r-abcadm
  (package
    (name "r-abcadm")
    (version "1.0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "abcADM" version))
       (sha256
        (base32
         "0vcabnnnwc0psv9v3rda5aap9s8cq1pjh02zva3ki64hlavf2a10"))))
    (properties `((upstream-name . "abcADM")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-bh" ,r-bh)
       ("r-rcpp" ,r-rcpp)))
    (home-page "https://cran.r-project.org/web/packages/abcADM/")
    (synopsis "Fit accumulated damage models and estimate reliability using ABC")
    (description
     "This package provides tools to estimate parameters of accumulated
damage (load duration) models based on failure time data under a Bayesian
framework, using @dfn{Approximate Bayesian Computation} (ABC), and to assess
long-term reliability under stochastic load profiles.")
    (license license:gpl3)))

(define-public r-rglpk
  (package
    (name "r-rglpk")
    (version "0.6-4")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "Rglpk" version))
       (sha256
        (base32
         "19mzpyimzq9zqnbi05j79b2di3nzaln8swggs9p8sqdr60qvr3d2"))))
    (properties `((upstream-name . "Rglpk")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-slam" ,r-slam)))
    (inputs
     `(("glpk" ,glpk)))
    (home-page "https://r-forge.r-project.org/projects/rglp/")
    (synopsis "R interface to the GNU Linear Programming Kit")
    (description
     "This package provides an R interface to the GNU Linear Programming Kit,
software for solving large-scale @dfn{linear programming} (LP), @dfn{mixed
integer linear programming} (MILP) and other related problems.")
    ;; Either license
    (license (list license:gpl2 license:gpl3))))

(define-public r-abcdefba
  (package
    (name "r-abcdefba")
    (version "0.4")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "abcdeFBA" version))
       (sha256
        (base32
         "1rxjripy8v6bxi25vdfjnbk24zkmf752qbl73cin6nvnqflwxkx4"))))
    (properties `((upstream-name . "abcdeFBA")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-corrplot" ,r-corrplot)
       ("r-lattice" ,r-lattice)
       ("r-rgl" ,r-rgl)
       ("r-rglpk" ,r-rglpk)))
    (home-page "https://cran.r-project.org/web/packages/abcdeFBA/")
    (synopsis "A-Biologist-Can-Do-Everything of Flux Balance Analysis with this package")
    (description
     "This package provides functions for Constraint Based Simulation using
Flux Balance Analysis and informative analysis of the data generated during
simulation.")
    (license license:gpl2)))

(define-public r-abcrlda
  (package
    (name "r-abcrlda")
    (version "1.0.2")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "abcrlda" version))
       (sha256
        (base32
         "0zjdrbg3zx0znqnh0dvmifs9c12b8vjhbaf3nbwab9xh25nsmg75"))))
    (properties `((upstream-name . "abcrlda")))
    (build-system r-build-system)
    (home-page "https://ieeexplore.ieee.org/document/8720003/")
    (synopsis "Asymptotically bias-corrected regularized linear discriminant analysis")
    (description
     "This package offers methods to perform @dfn{asymptotically
bias-corrected regularized linear discriminant analysis} (ABC_RLDA) for
cost-sensitive binary classification.  The bias-correction is an estimate of
the bias term added to regularized discriminant analysis that minimizes the
overall risk.")
    (license license:gpl3)))

(define-public r-abemus
  (package
    (name "r-abemus")
    (version "1.0.1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "abemus" version))
       (sha256
        (base32
         "1dhllb184byp1yl15rg2w02zgw3iajag7cxshirg47mnmm7n70bb"))))
    (properties `((upstream-name . "abemus")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-data-table" ,r-data-table)))
    (home-page "https://cran.r-project.org/web/packages/abemus/")
    (synopsis "Adaptive base error model in ultra-deep sequencing data")
    (description
     "This package provides an implementation of @dfn{Adaptive Base Error
Model in Ultra-deep Sequencing data} (ABEMUS), which combines
platform-specific genetic knowledge and empirical signal to readily detect and
quantify somatic @dfn{single nucleotide variants} (SNVs) in @dfn{circulating
cell free DNA} (cfDNA).")
    (license license:gpl3)))

;; This package includes minified JavaScript files.  When upgrading please
;; check that there are no new minified JavaScript files.
(define-public r-rintrojs
  (package
    (name "r-rintrojs")
    (version "0.2.2")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "rintrojs" version))
       (sha256
        (base32
         "0vyqb3pyrh12saddar71ac9csn2vkd2j8ln6ygpqys8ky1lc3427"))))
    (properties `((upstream-name . "rintrojs")))
    (build-system r-build-system)
    (arguments
     `(#:modules ((guix build utils)
                  (guix build r-build-system)
                  (srfi srfi-1)
                  (ice-9 popen))
       #:phases
       (modify-phases %standard-phases
         (add-after 'unpack 'process-javascript
           (lambda* (#:key inputs #:allow-other-keys)
             (with-directory-excursion "inst/javascript/introjs/"
               (call-with-values
                   (lambda ()
                     (unzip2
                      `((,(assoc-ref inputs "intro.js")
                         "intro.min.js"))))
                 (lambda (sources targets)
                   (for-each (lambda (source target)
                               (format #t "Processing ~a --> ~a~%"
                                       source target)
                               (let ((minified (open-pipe* OPEN_READ "uglify-js" source)))
                                 (call-with-output-file target
                                   (lambda (port)
                                     (dump-port minified port)))))
                             sources targets))))
             #t)))))
    (native-inputs
     `(("uglify-js" ,uglify-js)
       ("intro.js"
        ,(origin
           (method url-fetch)
           (uri "https://raw.githubusercontent.com/usablica/intro.js/v2.9.3/intro.js")
           (sha256
            (base32
             "1qf8n1sfy9qkiqqnfgg0xbhmfgh0g3mqsjas8qhz230h3zzlzxj8"))))))
    (propagated-inputs
     `(("r-jsonlite" ,r-jsonlite)
       ("r-shiny" ,r-shiny)))
    (home-page "https://github.com/carlganz/rintrojs")
    (synopsis "Wrapper for the Intro.js library")
    (description
     "This package provides a wrapper for the @url{http://www.introjs.com,
Intro.js} library.  This package makes it easy to include step-by-step
introductions, and clickable hints in a Shiny application.  It supports both
static introductions in the UI, and programmatic introductions from the
server-side.")
    (license license:agpl3+)))

(define-public r-sysfonts
  (package
    (name "r-sysfonts")
    (version "0.8")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "sysfonts" version))
       (sha256
        (base32
         "0wng902plryf2d8fc7k7m3jx11acz51kb2d91cqbyhq7xpk06z43"))))
    (properties `((upstream-name . "sysfonts")))
    (build-system r-build-system)
    (inputs
     `(("freetype" ,freetype)
       ("libpng" ,libpng)
       ("zlib" ,zlib)))
    (native-inputs
     `(("pkg-config" ,pkg-config)))
    (home-page "https://github.com/yixuan/sysfonts")
    (synopsis "Loading fonts into R")
    (description
     "This is a package to simplify loading of system fonts and Google Fonts
into R, in order to support other packages.")
    (license license:gpl2)))

(define-public r-showtextdb
  (package
    (name "r-showtextdb")
    (version "2.0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "showtextdb" version))
       (sha256
        (base32
         "1qwwj9x2jvadvwn60h75k99c9xi7yhqjsgaakahz5paxgj583bsh"))))
    (properties `((upstream-name . "showtextdb")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-sysfonts" ,r-sysfonts)))
    (home-page "https://cran.r-project.org/web/packages/showtextdb/")
    (synopsis "Font files for the 'showtext' package")
    (description
     "This package provides font files that can be used by the @code{showtext}
package.")
    (license license:asl2.0)))

(define-public r-showtext
  (package
    (name "r-showtext")
    (version "0.7-1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "showtext" version))
       (sha256
        (base32
         "0a5gg72bfrc7wm0phj1aflj1wc08kfi81ac32na6ya9s2ivyimw5"))))
    (properties `((upstream-name . "showtext")))
    (build-system r-build-system)
    (inputs
     `(("freetype" ,freetype)
       ("libpng" ,libpng)
       ("zlib" ,zlib)))
    (propagated-inputs
     `(("r-showtextdb" ,r-showtextdb)
       ("r-sysfonts" ,r-sysfonts)))
    (native-inputs `(("pkg-config" ,pkg-config)))
    (home-page "https://github.com/yixuan/showtext")
    (synopsis "Using fonts more easily in R graphs")
    (description
     "This package aims to make it easy to use various types of
fonts (TrueType, OpenType, Type 1, web fonts, etc.) in R graphs, and supports
most output formats of R graphics including PNG, PDF and SVG.  Text glyphs
will be converted into polygons or raster images, hence after the plot has
been created, it no longer relies on the font files.  No external software
such as Ghostscript is needed to use this package.")
    (license license:asl2.0)))

(define-public r-emojifont
  (package
    (name "r-emojifont")
    (version "0.5.3")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "emojifont" version))
       (sha256
        (base32
         "1cdrrl3hvrs8rskyy6zgr7q2mmg8yb9k8sld1m64zsp7y009g19k"))))
    (properties `((upstream-name . "emojifont")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-ggplot2" ,r-ggplot2)
       ("r-proto" ,r-proto)
       ("r-showtext" ,r-showtext)
       ("r-sysfonts" ,r-sysfonts)))
    (home-page "https://guangchuangyu.github.io/emojifont")
    (synopsis "Emoji and Font Awesome in R graphics")
    (description
     "This package enables the use of emoji and the Font Awesome glyphs in
both base and ggplot2 graphics.")
    (license license:artistic2.0)))

(define-public r-abstractr
  (package
    (name "r-abstractr")
    (version "0.1.0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "abstractr" version))
       (sha256
        (base32
         "1ymwp7syrynwd4i8aj2x5n8jdi9d96fjzl6jb09n0bnr5fgl7vig"))))
    (properties `((upstream-name . "abstractr")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-colourpicker" ,r-colourpicker)
       ("r-emojifont" ,r-emojifont)
       ("r-ggplot2" ,r-ggplot2)
       ("r-gridextra" ,r-gridextra)
       ("r-rintrojs" ,r-rintrojs)
       ("r-shiny" ,r-shiny)
       ("r-shinythemes" ,r-shinythemes)))
    (home-page "https://matt-kumar.shinyapps.io/portfolio")
    (synopsis "R-Shiny application for creating visual abstracts")
    (description
     "This package provides an R Shiny application to create visual abstracts
for original research.  A variety of user defined options and formatting are
included.")
    (license license:gpl3)))

(define-public r-abtest
  (package
    (name "r-abtest")
    (version "0.2.0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "abtest" version))
       (sha256
        (base32
         "1ky3cf827kj24bhcpk00v5zl5jdkii1gca0x81ay1cjkzfispgws"))))
    (properties `((upstream-name . "abtest")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-matrix" ,r-matrix)
       ("r-mvtnorm" ,r-mvtnorm)
       ("r-plotrix" ,r-plotrix)
       ("r-rcolorbrewer" ,r-rcolorbrewer)
       ("r-rcpp" ,r-rcpp)
       ("r-sn" ,r-sn)
       ("r-truncnorm" ,r-truncnorm)
       ("r-vgam" ,r-vgam)))
    (home-page "https://cran.r-project.org/web/packages/abtest/")
    (synopsis "Bayesian A/B testing")
    (description
     "This package provides functions for Bayesian A/B testing including prior
elicitation options based on Kass and Vaidyanathan (1992)
@url{doi:10.1111/j.2517-6161.1992.tb01868.x}.")
    (license license:gpl2+)))

(define-public r-accept
  (package
    (name "r-accept")
    (version "0.7.1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "accept" version))
       (sha256
        (base32
         "0pn8q0jsi0nb2mm2kv6sjczflflshhy55y7nqqnk70yx9f6wm83y"))))
    (properties `((upstream-name . "accept")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-dplyr" ,r-dplyr)
       ("r-extrafont" ,r-extrafont)
       ("r-mass" ,r-mass)
       ("r-plotly" ,r-plotly)
       ("r-stringr" ,r-stringr)
       ("r-viridis" ,r-viridis)))
    (home-page "https://cran.r-project.org/web/packages/accept/")
    (synopsis "Acute COPD Exacerbation Prediction Tool (ACCEPT)")
    (description
     "This package allows clinicians to predict the rate and severity of
future acute exacerbation in @dfn{Chronic Obstructive Pulmonary
Disease} (COPD) patients, based on the clinical prediction model published in
Adibi et al. (2019) @url{doi:10.1101/651901}.")
    (license license:gpl3)))

(define-public r-smpracticals
  (package
    (name "r-smpracticals")
    (version "1.4-3")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "SMPracticals" version))
       (sha256
        (base32
         "0zxq84f9i3b86xx6msb25b61gyj9k09iab2b7wg4d93yas9qzayf"))))
    (properties `((upstream-name . "SMPracticals")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-ellipse" ,r-ellipse)
       ("r-mass" ,r-mass)
       ("r-nlme" ,r-nlme)
       ("r-survival" ,r-survival)))
    (home-page "http://statwww.epfl.ch/davison/SM/")
    (synopsis "Practicals for use with Davison (2003) Statistical Models")
    (description
     "This package contains the datasets and a few functions for use with the
practicals outlined in Appendix A of the book Statistical Models (Davison,
2003, Cambridge University Press).  The practicals themselves can be found at
@url{http://statwww.epfl.ch/davison/SM/}.")
    (license license:gpl2+)))

(define-public r-fgui
  (package
    (name "r-fgui")
    (version "1.0-8")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "fgui" version))
       (sha256
        (base32
         "024fzd1c7iwqprn26hwjb9l2qlvvyzl449d7iixy0x69djwsrysv"))))
    (properties `((upstream-name . "fgui")))
    (build-system r-build-system)
    (home-page
     "https://sites.google.com/site/thomashoffmannproject/software/fgui")
    (synopsis "Create GUI for R functions")
    (description
     "Rapidly create a GUI for a function you created by automatically
creating widgets for arguments of the function.  This package automatically
parses help routines for context-sensitive help to these arguments.  The
interface is essentially a wrapper to some Tcl/Tk routines to both simplify
and facilitate GUI creation.  More advanced Tcl/Tk routines/GUI objects can be
incorporated into the interface for greater customization for the more
experienced.")
    ;; Any version of the GPL.
    (license (list license:gpl2+ license:gpl3+))))

(define-public r-tcltk2
  (package
    (name "r-tcltk2")
    (version "1.2-11")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "tcltk2" version))
       (sha256
        (base32
         "1ibxld379600xx7kiqq3fck083s8psry12859980218rnzikl65d"))))
    (properties `((upstream-name . "tcltk2")))
    (build-system r-build-system)
    (inputs
     `(("tcl" ,tcl)
       ("tk" ,tk)))
    (home-page "https://www.sciviews.org/SciViews-R")
    (synopsis "Tcl/Tk additions")
    (description
     "This package provides a series of additional Tcl commands and Tk widgets
with style and various functions to supplement the tcltk package")
    (license license:lgpl3)))

(define-public r-accrual
  (package
    (name "r-accrual")
    (version "1.3")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "accrual" version))
       (sha256
        (base32
         "11clm9s5c5518nmp6hd6pjnp0s28y92b2i2x0xgj4j5g816p4j3z"))))
    (properties `((upstream-name . "accrual")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-fgui" ,r-fgui)
       ("r-smpracticals" ,r-smpracticals)
       ("r-tcltk2" ,r-tcltk2)))
    (home-page "https://cran.r-project.org/web/packages/accrual/")
    (synopsis "Bayesian accrual prediction")
    (description
     "Subject recruitment for medical research is challenging.  Slow patient
accrual leads to delay in research.  Accrual monitoring during the process of
recruitment is critical.  Researchers need reliable tools to manage the
accrual rate.  This package provides an implementation of a Bayesian method
that integrates researcher's experience on previous trials and data from the
current study, providing reliable prediction on accrual rate for clinical
studies.  It provides functions for Bayesian accrual prediction which can be
easily used by statisticians and clinical researchers.")
    (license license:gpl2)))

(define-public r-accrued
  (package
    (name "r-accrued")
    (version "1.4.1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "accrued" version))
       (sha256
        (base32
         "05g1jb5914z18rcai1ahn7nihn27vr2rnadwv94gc1j7ivvikvs5"))))
    (properties `((upstream-name . "accrued")))
    (build-system r-build-system)
    (home-page "https://cran.r-project.org/web/packages/accrued/")
    (synopsis "Data quality visualization tools for partially accruing data")
    (description
     "This is a package for visualizing data quality of partially accruing
data.")
    (license license:gpl3)))

(define-public r-mda
  (package
    (name "r-mda")
    (version "0.4-10")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "mda" version))
       (sha256
        (base32
         "19g6kn6g0shidrjfffklbmzc5w7mcimrxhagx4nmpslg59ibqdkh"))))
    (properties `((upstream-name . "mda")))
    (build-system r-build-system)
    (propagated-inputs `(("r-class" ,r-class)))
    (native-inputs `(("gfortran" ,gfortran)))
    (home-page "https://cran.r-project.org/web/packages/mda/")
    (synopsis "Mixture and flexible discriminant analysis")
    (description
     "This is a package for mixture and flexible discriminant analysis,
@dfn{multivariate adaptive regression splines} (MARS), BRUTO, and so on.")
    (license license:gpl2)))

(define-public r-elasticnet
  (package
    (name "r-elasticnet")
    (version "1.1.1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "elasticnet" version))
       (sha256
        (base32
         "0p9dplnsp28z4s2fl6afbwrgd0aj339fak8mmndicmrh7bb7rpmb"))))
    (properties `((upstream-name . "elasticnet")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-lars" ,r-lars)))
    (home-page "http://users.stat.umn.edu/~zouxx019/")
    (synopsis "Elastic-Net for sparse estimation and sparse PCA")
    (description
     "This package provides functions for fitting the entire solution path of
the Elastic-Net and also provides functions for estimating sparse Principal
Components.  The Lasso solution paths can be computed by the same function.")
    (license license:gpl2+)))

(define-public r-sparselda
  (package
    (name "r-sparselda")
    (version "0.1-9")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "sparseLDA" version))
       (sha256
        (base32
         "1k3sw9kc40yxnfss4vrsx34qxmv8ssddyhbfjhxrdldvblhbwchb"))))
    (properties `((upstream-name . "sparseLDA")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-elasticnet" ,r-elasticnet)
       ("r-mass" ,r-mass)
       ("r-mda" ,r-mda)))
    (home-page "https://www.imm.dtu.dk/~lkhc/")
    (synopsis "Sparse discriminant analysis")
    (description
     "This package performs sparse linear discriminant analysis for Gaussians
and mixture of Gaussian models.")
    (license license:gpl2+)))

(define-public r-accsda
  (package
    (name "r-accsda")
    (version "1.0.0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "accSDA" version))
       (sha256
        (base32
         "0sgxy5y8kkc1n35657kifwfjsba7y5m1vbr7rkk5lmbpkzahqm61"))))
    (properties `((upstream-name . "accSDA")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-ggplot2" ,r-ggplot2)
       ("r-ggthemes" ,r-ggthemes)
       ("r-gridextra" ,r-gridextra)
       ("r-mass" ,r-mass)
       ("r-rarpack" ,r-rarpack)
       ("r-sparselda" ,r-sparselda)))
    (home-page "https://github.com/gumeo/accSDA/wiki")
    (synopsis "Accelerated sparse discriminant analysis")
    (description
     "This package provides an implementation of sparse linear discriminant
analysis, which is a supervised classification method for multiple classes.
Various novel optimization approaches to this problem are implemented
including @dfn{alternating direction method of multipliers} (ADMM),
@dfn{proximal gradient} (PG) and @dfn{accelerated proximal gradient} (APG).
Functions for performing cross validation are also supplied along with basic
prediction and plotting functions.  @dfn{Sparse zero variance
discriminant} (SZVD) analysis is also included in the package.")
    (license license:gpl2+)))

(define-public r-ace2fastq
  (package
    (name "r-ace2fastq")
    (version "0.6.0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "ace2fastq" version))
       (sha256
        (base32
         "09kk3yyqnr2xp820g0p3aai9a21figigjr9lxkr3zjq2d8gzwfic"))))
    (properties `((upstream-name . "ace2fastq")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-stringr" ,r-stringr)))
    (home-page "https://github.com/c5sire/ace2fastq")
    (synopsis "ACE file to FASTQ converter")
    (description
     "The ACE file format is used in genomics to store contigs from sequencing
machines.  This tools converts it into FASTQ format.  Both formats contain the
sequence characters and their corresponding quality information.  Unlike the
FASTQ file, the ACE file stores the quality values numerically.  The
conversion algorithm uses the standard Sanger formula.  The package
facilitates insertion into pipelines, and content inspection.")
    (license license:gpl3)))

(define-public r-rngwell
  (package
    (name "r-rngwell")
    (version "0.10-6")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "rngWELL" version))
       (sha256
        (base32
         "0pjjcs9pqj7mf0mhb2cwd0aanqpwnm65bm86hk6mi2vw8rgnj2vv"))))
    (properties `((upstream-name . "rngWELL")))
    (build-system r-build-system)
    (home-page "https://cran.r-project.org/web/packages/rngWELL/")
    (synopsis "Toolbox for WELL random number generators")
    (description
     "This is a dedicated package to WELL pseudo random generators, which were
introduced in Panneton et al. (2006), ``Improved Long-Period Generators Based
on Linear Recurrences Modulo 2'', ACM Transactions on Mathematical Software.")
    (license license:bsd-3)))

(define-public r-randtoolbox
  (package
    (name "r-randtoolbox")
    (version "1.30.1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "randtoolbox" version))
       (sha256
        (base32
         "0qg20ar6qns858jdzqhmfq7yji81czhr6cim257958gqpj66sn95"))))
    (properties `((upstream-name . "randtoolbox")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-rngwell" ,r-rngwell)))
    (native-inputs
     `(("gfortran" ,gfortran)))
    (home-page "https://cran.r-project.org/web/packages/randtoolbox/")
    (synopsis "Toolbox for pseudo and quasi random number generation")
    (description
     "This package provides

@enumerate
@item pseudo random generators, such as general linear
congruential generators, multiple recursive generators and generalized
feedback shift register (SF-Mersenne Twister algorithm and WELL
generators)

@item quasi random generators, such as the Torus algorithm, the Sobol
sequence, the Halton sequence (including the Van der Corput sequence), and

@item some generator tests: the gap test, the serial test, the poker test.
@end enumerate

See e.g. Gentle (2003) @url{doi:10.1007/b97336}.")
    (license license:bsd-3)))

(define-public r-lhs
  (package
    (name "r-lhs")
    (version "1.0.1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "lhs" version))
       (sha256
        (base32
         "0lzaqr7xi3ckln5nglv5xf5njm359slpz1jc6s02hpsqdw6armd4"))))
    (properties `((upstream-name . "lhs")))
    (build-system r-build-system)
    (propagated-inputs `(("r-rcpp" ,r-rcpp)))
    (home-page "https://github.com/bertcarnell/lhs")
    (synopsis "Latin Hypercube Samples")
    (description
     "This package provides a number of methods for creating and augmenting
Latin Hypercube Samples.")
    (license license:gpl3)))

(define-public r-acebayes
  (package
    (name "r-acebayes")
    (version "1.9")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "acebayes" version))
       (sha256
        (base32
         "1imfwm1vpbb24vfmfn1nljhmaz8429mwjihw34892p387s8h7xz2"))))
    (properties `((upstream-name . "acebayes")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-compare" ,r-compare)
       ("r-lhs" ,r-lhs)
       ("r-randtoolbox" ,r-randtoolbox)
       ("r-rcpp" ,r-rcpp)
       ("r-rcpparmadillo" ,r-rcpparmadillo)))
    (home-page "https://cran.r-project.org/web/packages/acebayes/")
    (synopsis "Optimal Bayesian experimental design using the ACE algorithm")
    (description
     "Finding an optimal Bayesian experimental design involves maximizing an
objective function given by the expectation of some appropriately chosen
utility function with respect to the joint distribution of unknown
quantities (including responses).  This objective function is usually not
available in closed form and the design space can be continuous and of high
dimensionality.  This package uses @dfn{Approximate Coordinate Exchange} (ACE)
to maximise an approximation to the expectation of the utility function.")
    (license license:gpl2)))

(define-public r-acet
  (package
    (name "r-acet")
    (version "1.8.0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "ACEt" version))
       (sha256
        (base32
         "0626d6kg485xjya164wagrr5z223jvi93ywbwpdns7fkm03c0dlq"))))
    (properties `((upstream-name . "ACEt")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-bh" ,r-bh)
       ("r-mass" ,r-mass)
       ("r-rcpp" ,r-rcpp)
       ("r-rcpparmadillo" ,r-rcpparmadillo)))
    (home-page "https://cran.r-project.org/web/packages/ACEt/")
    (synopsis "Estimating dynamic heritability and twin model comparison")
    (description
     "This package supports twin models that are able to estimate the dynamic
behaviour of the variance components in the classical twin models with respect
to age using B-splines and P-splines.")
    (license license:gpl2+)))

(define-public r-acfmperiod
  (package
    (name "r-acfmperiod")
    (version "1.0.0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "acfMPeriod" version))
       (sha256
        (base32
         "1yww8isfrbs2v9s94hx7p2imyszcgadwafdgpj438n2ik0q6p9d5"))))
    (properties `((upstream-name . "acfMPeriod")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-mass" ,r-mass)))
    (home-page "https://cran.r-project.org/web/packages/acfMPeriod/")
    (synopsis "Estimation of the ACF from the M-periodogram")
    (description
     "This package support non-robust and robust computations of the sample
autocovariance (ACOVF) and sample autocorrelation functions (ACF) of
univariate and multivariate processes.  The methodology consists in reversing
the diagonalization procedure involving the periodogram or the
cross-periodogram and the Fourier transform vectors, and, thus, obtaining the
ACOVF or the ACF as discussed in Fuller (1995)
@url{doi:10.1002/9780470316917}.  The robust version is obtained by fitting
robust M-regressors to obtain the M-periodogram or M-cross-periodogram as
discussed in Reisen et al. (2017) @url{doi:10.1016/j.jspi.2017.02.008}.")
    (license license:gpl2+)))

(define-public r-gamlss-data
  (package
    (name "r-gamlss-data")
    (version "5.1-4")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "gamlss.data" version))
       (sha256
        (base32
         "1dgfspbmps6ipzcmw681wjdp320nm50dwsxafgrcwxndqgc7fdqd"))))
    (properties `((upstream-name . "gamlss.data")))
    (build-system r-build-system)
    (home-page "http://www.gamlss.org/")
    (synopsis "GAMLSS data")
    (description
     "This package provides data used as examples to demonstrate GAMLSS
models.")
    ;; Either version of the license
    (license (list license:gpl2 license:gpl3))))

(define-public r-gamlss
  (package
    (name "r-gamlss")
    (version "5.1-6")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "gamlss" version))
       (sha256
        (base32
         "16b7ick1khvldbvfmmpw9cjs1vznnrisvifq7717fxzd8c9s5jdr"))))
    (properties `((upstream-name . "gamlss")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-gamlss-data" ,r-gamlss-data)
       ("r-gamlss-dist" ,r-gamlss-dist)
       ("r-mass" ,r-mass)
       ("r-nlme" ,r-nlme)
       ("r-survival" ,r-survival)))
    (home-page "http://www.gamlss.org/")
    (synopsis "Generalized additive models for location scale and shape")
    (description
     "This package provides functions for fitting the generalized additive
models for location scale and shape introduced by Rigby and
Stasinopoulos (2005), @url{doi:10.1111/j.1467-9876.2005.00510.x}.  The models
use a distributional regression approach where all the parameters of the
conditional distribution of the response variable are modelled using
explanatory variables.")
    ;; Either version of the license
    (license (list license:gpl2 license:gpl3))))

(define-public r-acid
  (package
    (name "r-acid")
    (version "1.1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "acid" version))
       (sha256
        (base32
         "030i0y8s283ivbsmjccpbv9v7mgbcg2jk9df7vgcbbns74swf9hd"))))
    (properties `((upstream-name . "acid")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-gamlss" ,r-gamlss)
       ("r-gamlss-dist" ,r-gamlss-dist)
       ("r-hmisc" ,r-hmisc)))
    (home-page "https://cran.r-project.org/web/packages/acid/")
    (synopsis "Analysing conditional income distributions")
    (description
     "This package provides functions for the analysis of income distributions
for subgroups of the population as defined by a set of variables like age,
gender, region, etc.  This entails a Kolmogorov-Smirnov test for a mixture
distribution as well as functions for moments, inequality measures, entropy
measures and polarisation measures of income distributions.  This package thus
aides the analysis of income inequality by offering tools for the exploratory
analysis of income distributions at the disaggregated level.")
    (license license:gpl3)))

(define-public r-acm4r
  (package
    (name "r-acm4r")
    (version "1.0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "acm4r" version))
       (sha256
        (base32
         "1wqzc35i1rshx0zlmas8y4qkkvy6h9r4i4apscjjv1xg2wjflzxa"))))
    (properties `((upstream-name . "acm4r")))
    (build-system r-build-system)
    (propagated-inputs `(("r-mass" ,r-mass)))
    (home-page "https://cran.r-project.org/web/packages/acm4r/")
    (synopsis "Align-and-count method comparisons of RFLP data")
    (description
     "This is a package to compare sequence fragment lengths or molecular
weights from pairs of lanes.  The number of matching bands in the
@dfn{Restriction Fragment Length Polymorphism} (RFLP) data is calculated using
the align-and-count method.")
    ;; Any version of the GPL
    (license (list license:gpl2+ license:gpl3+))))

(define-public r-filematrix
  (package
    (name "r-filematrix")
    (version "1.3")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "filematrix" version))
       (sha256
        (base32
         "1v3aj1ng742msb0sfdnjsbqb508mqjf8jlq2v33vxldhradw5w0b"))))
    (properties `((upstream-name . "filematrix")))
    (build-system r-build-system)
    ;; These inputs are needed for vignettes
    (native-inputs
     `(("r-knitr" ,r-knitr)
       ("r-rmarkdown" ,r-rmarkdown)
       ("pandoc-citeproc" ,ghc-pandoc-citeproc)))
    (home-page "https://github.com/andreyshabalin/filematrix")
    (synopsis "File-backed matrix class with convenient read and write access")
    (description
     "This package provides an interface for working with large matrices
stored in files, not in computer memory.  It supports multiple non-character
data types (double, integer, logical and raw) of various sizes (e.g.  8 and 4
byte real values).  Access to parts of the matrix is done by indexing, exactly
as with usual R matrices.  It supports very large matrices; the package has
been tested on multi-terabyte matrices.  It allows for more than 2^32 rows or
columns, ad allows for quick addition of extra columns to a filematrix.")
    (license license:lgpl3)))

(define-public r-acmeeqtl
  (package
    (name "r-acmeeqtl")
    (version "1.6")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "ACMEeqtl" version))
       (sha256
        (base32
         "049xjv2ym35bbn43zwi68cq27fwdh404vp0r2ca5gxgmmx8kj1cz"))))
    (properties `((upstream-name . "ACMEeqtl")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-filematrix" ,r-filematrix)))
    (home-page "https://github.com/andreyshabalin/ACMEeqtl")
    (synopsis "Estimation of interpretable eQTL effect sizes")
    (description
     "This package provides a non-linear model, termed ACME, that reflects a
parsimonious biological model for allelic contributions of cis-acting eQTLs.
With non-linear least-squares algorithm the maximum likelihood parameters can
be estimated.  The ACME model provides interpretable effect size estimates and
p-values with well controlled Type-I error.")
    (license license:lgpl3)))

(define-public r-acmer
  (package
    (name "r-acmer")
    (version "1.1.0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "acmeR" version))
       (sha256
        (base32
         "000b2hqlhj93958nddw0fqb15ahigs08najv2miivym046x04mf7"))))
    (properties `((upstream-name . "acmeR")))
    (build-system r-build-system)
    (propagated-inputs `(("r-foreign" ,r-foreign)))
    (home-page "https://cran.r-project.org/web/packages/acmeR/")
    (synopsis "ACME estimator of bird and bat mortality by wind turbines")
    (description
     "This package provides an implementation of the ACME estimator, described
in Wolpert (2015), ACME: A Partially Periodic Estimator of Avian & Chiropteran
Mortality at Wind Turbines.  Unlike most other models, this estimator supports
decreasing-hazard Weibull model for persistence; decreasing search proficiency
as carcasses age; variable bleed-through at successive searches; and interval
mortality estimates.  The package provides, based on search data, functions
for estimating the mortality inflation factor in Frequentist and Bayesian
settings.")
    (license license:expat)))

(define-public r-r-huge
  (package
    (name "r-r-huge")
    (version "0.9.0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "R.huge" version))
       (sha256
        (base32
         "13p558qalv60pgr24nsm6mi92ryj65rsbqa6pgdwy0snjqx12bgi"))))
    (properties `((upstream-name . "R.huge")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-r-methodss3" ,r-r-methodss3)
       ("r-r-oo" ,r-r-oo)
       ("r-r-utils" ,r-r-utils)))
    (home-page "https://github.com/HenrikBengtsson/R.huge")
    (synopsis "Methods for accessing huge amounts of data")
    (description
     "This is a deprecated package for accessing huge amounts of data.
  Cross-platform alternatives are the following packages: bigmemory (CRAN),
ff (CRAN), or BufferedMatrix (Bioconductor).  The main usage of it was inside
the @code{aroma.affymetrix} package.")
    (license license:lgpl2.1+)))

(define-public r-r-filesets
  (package
    (name "r-r-filesets")
    (version "2.13.0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "R.filesets" version))
       (sha256
        (base32
         "124rygq0bl9n4akxcm868nl30cyk3rz0iprb98zlpk62gci9f5fg"))))
    (properties `((upstream-name . "R.filesets")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-digest" ,r-digest)
       ("r-r-cache" ,r-r-cache)
       ("r-r-methodss3" ,r-r-methodss3)
       ("r-r-oo" ,r-r-oo)
       ("r-r-utils" ,r-r-utils)))
    (home-page "https://github.com/HenrikBengtsson/R.filesets")
    (synopsis "Easy handling of and access to files")
    (description
     "This package provides classes and methods to locate, setup, subset,
navigate and iterate file sets, i.e. sets of files located in one or more
directories on the file system.  The API is designed such that these classes
can be extended via inheritance to provide a richer API for special file
formats.  Moreover, a specific name format is defined such that filenames and
directories can be considered to have full names which consists of a name
followed by comma-separated tags.  This adds additional flexibility to
identify file sets and individual files.")
    (license license:lgpl2.1+)))

(define-public r-r-devices
  (package
    (name "r-r-devices")
    (version "2.16.1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "R.devices" version))
       (sha256
        (base32
         "15zlnq3g27whq26fbcy5zfl5hiddm256h4rga4frblg6wqlbkvdd"))))
    (properties `((upstream-name . "R.devices")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-base64enc" ,r-base64enc)
       ("r-r-methodss3" ,r-r-methodss3)
       ("r-r-oo" ,r-r-oo)
       ("r-r-utils" ,r-r-utils)))
    (home-page "https://github.com/HenrikBengtsson/R.devices")
    (synopsis "Unified handling of graphics devices")
    (description
     "This package provides functions for creating plots and image files in a
unified way regardless of output format (EPS, PDF, PNG, SVG, TIFF, WMF, etc.).
Default device options as well as scales and aspect ratios are controlled in a
uniform way across all device types.  Switching output format requires minimal
changes in code.  This package is ideal for large-scale batch processing,
because it will never leave open graphics devices or incomplete image files
behind, even on errors or user interrupts.")
    (license license:lgpl2.1+)))

(define-public r-acnr
  (package
    (name "r-acnr")
    (version "1.0.0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "acnr" version))
       (sha256
        (base32
         "087hq4i7jp67ba2finzsqjfnqbiprl33na6ryjv9zqzsdawj9cym"))))
    (properties `((upstream-name . "acnr")))
    (build-system r-build-system)
    (home-page "https://github.com/mpierrejean/acnr")
    (synopsis "Annotated copy-number regions")
    (description
     "This package provides SNP array data from different types of copy-number
regions.  These regions were identified manually by the authors of the package
and may be used to generate realistic data sets with known truth.")
    (license license:lgpl2.1+)))

(define-public r-acopula
  (package
    (name "r-acopula")
    (version "0.9.3")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "acopula" version))
       (sha256
        (base32
         "0vvbbw8pfs9jwfz5c57lw48pr0qj661r0ys007q6zf9jmlrhx1ln"))))
    (properties `((upstream-name . "acopula")))
    (build-system r-build-system)
    (home-page "https://cran.r-project.org/web/packages/acopula/")
    (synopsis "Modelling dependence with multivariate Archimax copulas")
    (description
     "Archimax copulas are a mixture of Archimedean and EV copulas.  This
package provides definitions of several parametric families of generator and
dependence function, computes CDF and PDF, estimates parameters, tests for
goodness of fit, generates random sample and checks copula properties for
custom constructs.  In the 2-dimensional case explicit formulas for density
are used, contrary to higher dimensions when all derivatives are linearly
approximated.  Several non-archimax families (normal, FGM, Plackett) are
provided as well.")
    (license license:gpl2)))

(define-public r-tuner
  (package
    (name "r-tuner")
    (version "1.3.3")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "tuneR" version))
       (sha256
        (base32
         "0av978m4h2iqazyfq6n2cgkh4wpllihh7s29lah2nb8ngc0w5hxx"))))
    (properties `((upstream-name . "tuneR")))
    (build-system r-build-system)
    (propagated-inputs `(("r-signal" ,r-signal)))
    (home-page "https://cran.r-project.org/web/packages/tuneR/")
    (synopsis "Analysis of music and speech")
    (description
     "This is a package for the analysis of music and speech.  Analyze music
and speech, extract features like MFCCs, handle wave files and their
representation in various ways, read MP3, read MIDI, perform steps of a
transcription, ...")
    ;; Either of these versions.
    (license (list license:gpl2 license:gpl3))))

(define-public r-seewave
  (package
    (name "r-seewave")
    (version "2.1.5")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "seewave" version))
       (sha256
        (base32
         "1qg8f5gik9pw6f9mcxqmrc9x3003s8vdm6g01pjjpyc9qaqiz2vi"))))
    (properties `((upstream-name . "seewave")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-tuner" ,r-tuner)))
    (home-page "http://rug.mnhn.fr/seewave")
    (synopsis "Sound analysis and synthesis")
    (description
     "This package provides functions for analysing, manipulating, displaying,
editing and synthesizing time waves (particularly sound).  This package
processes time analysis (oscillograms and envelopes), spectral content,
resonance quality factor, entropy, cross correlation and autocorrelation,
zero-crossing, dominant frequency, analytic signal, frequency coherence, 2D
and 3D spectrograms and many other analyses.")
    (license license:gpl2+)))

(define-public r-acousticndlcoder
  (package
    (name "r-acousticndlcoder")
    (version "1.0.2")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "AcousticNDLCodeR" version))
       (sha256
        (base32
         "1fgzgwanpv2pzy74xdk3hamc44p8qch467wh163dxby8jr9ik0sb"))))
    (properties
     `((upstream-name . "AcousticNDLCodeR")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-seewave" ,r-seewave)
       ("r-tuner" ,r-tuner)
       ("r-zoo" ,r-zoo)))
    (home-page "https://cran.r-project.org/web/packages/AcousticNDLCodeR/")
    (synopsis "Coding sound files for use with NDL")
    (description
     "Make acoustic cues to use with the R package @code{ndl}.
The package implements functions used in the PLoS ONE paper \"Words from
spontaneous conversational speech can be recognized with human-like accuracy
by an error-driven learning algorithm that discriminates between meanings
straight from smart acoustic features, bypassing the phoneme as recognition
unit.\" @url{doi:10.1371/journal.pone.0174623}")
    (license license:gpl2+)))

(define-public r-acp
  (package
    (name "r-acp")
    (version "2.1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "acp" version))
       (sha256
        (base32
         "0lcwbjcyyr32m6qjmjqh25qjwrbyqj1n092xhgbhxzd8fslppnmn"))))
    (properties `((upstream-name . "acp")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-quantmod" ,r-quantmod)
       ("r-tseries" ,r-tseries)))
    (home-page "https://cran.r-project.org/web/packages/acp/")
    (synopsis "Autoregressive conditional Poisson")
    (description
     "This package supports the analysis of count data exhibiting
autoregressive properties, using the @dfn{Autoregressive Conditional Poisson}
model (ACP(p,q)) proposed by Heinen (2003).")
    (license license:gpl2)))

(define-public r-ada
  (package
    (name "r-ada")
    (version "2.0-5")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "ada" version))
       (sha256
        (base32
         "1h3a07czp0w3hrhjcg1fz721y8vsfclzqi3rq8qfzgpfb4h1f06r"))))
    (properties `((upstream-name . "ada")))
    (build-system r-build-system)
    (propagated-inputs `(("r-rpart" ,r-rpart)))
    (home-page "https://cran.r-project.org/web/packages/ada/")
    (synopsis "Stochastic boosting")
    (description
     "This package provides a straightforward, well-documented, and broad
boosting routine for classification, ideally suited for small to
moderate-sized data sets.  It performs discrete, real, and gentle boost under
both exponential and logistic loss on a given data set.")
    ;; Any version of the GPL.
    (license (list license:gpl2+ license:gpl3+))))

(define-public r-genalg
  (package
    (name "r-genalg")
    (version "0.2.0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "genalg" version))
       (sha256
        (base32
         "1wzfamq8k5yhwbdx0wy1w5bks93brj0p890xxc4yqrja4w38ja3s"))))
    (properties `((upstream-name . "genalg")))
    (build-system r-build-system)
    (home-page "https://github.com/egonw/genalg")
    (synopsis "R based genetic algorithm")
    (description
     "This package provides an R based genetic algorithm for binary and
floating point chromosomes.")
    (license license:gpl2)))

(define-public r-kernelfactory
  (package
    (name "r-kernelfactory")
    (version "0.3.0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "kernelFactory" version))
       (sha256
        (base32
         "001kw9k3ivd4drd4mwqapkkk3f4jgljiaprhg2630hmll064s89j"))))
    (properties `((upstream-name . "kernelFactory")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-auc" ,r-auc)
       ("r-genalg" ,r-genalg)
       ("r-kernlab" ,r-kernlab)
       ("r-randomforest" ,r-randomforest)))
    (home-page "https://cran.r-project.org/web/packages/kernelFactory/")
    (synopsis "Ensemble of kernel machines")
    (description
     "Kernel factory is an ensemble method where each base classifier (random
forest) is fit on the kernel matrix of a subset of the training data.")
    (license license:gpl2+)))

(define-public r-dummies
  (package
    (name "r-dummies")
    (version "1.5.6")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "dummies" version))
       (sha256
        (base32
         "01f84crqx17xd6xy55qxlvsj3knm8lhw7jl26p2rh2w3y0nvqlbm"))))
    (properties `((upstream-name . "dummies")))
    (build-system r-build-system)
    (home-page "https://decisionpatterns.com")
    (synopsis "Create dummy/indicator variables flexibly and efficiently")
    (description
     "This package lets you expand factors, characters and other eligible
classes into dummy/indicator variables.")
    (license license:gpl2+)))

(define-public r-acrm
  (package
    (name "r-acrm")
    (version "0.1.1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "aCRM" version))
       (sha256
        (base32
         "0kzp568hd9c9a9qgniia5s5gv0q5f89xfvvwpzb197gqhs3x092v"))))
    (properties `((upstream-name . "aCRM")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-ada" ,r-ada)
       ("r-dummies" ,r-dummies)
       ("r-kernelfactory" ,r-kernelfactory)
       ("r-randomforest" ,r-randomforest)))
    (home-page "https://cran.r-project.org/web/packages/aCRM/")
    (synopsis "Convenience functions for analytical customer relationship management")
    (description
     "This package provides convenience functions for data preparation and
modeling often used in @dfn{analytical customer relationship
management} (aCRM).")
    (license license:gpl2+)))

(define-public r-treeclust
  (package
    (name "r-treeclust")
    (version "1.1-7")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "treeClust" version))
       (sha256
        (base32
         "1s7kh6q0bkixsygrip95zf1bi10ihddsa5lq9dfxd68yh8rsby6z"))))
    (properties `((upstream-name . "treeClust")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-cluster" ,r-cluster)
       ("r-rpart" ,r-rpart)))
    (home-page "https://cran.r-project.org/web/packages/treeClust/")
    (synopsis "Cluster distances through trees")
    (description
     "This package provides tools to create a measure of inter-point
dissimilarity useful for clustering mixed data, and, optionally, perform the
clustering.")
    (license license:gpl2+)))

(define-public r-acrosstic
  (package
    (name "r-acrosstic")
    (version "1.0-3")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "AcrossTic" version))
       (sha256
        (base32
         "03180h79jhjd66ibrnsfp3yyp2jlfysp7cymw46phzj2palghsc0"))))
    (properties `((upstream-name . "AcrossTic")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-lpsolve" ,r-lpsolve)
       ("r-treeclust" ,r-treeclust)))
    (home-page "https://cran.r-project.org/web/packages/AcrossTic/")
    (synopsis "Cost-minimal regular spanning subgraph with TreeClust")
    (description
     "This is a package for constructing minimum-cost regular spanning
subgraph as part of a non-parametric two-sample test for equality of
distribution.")
    (license license:gpl2+)))

(define-public r-acrt
  (package
    (name "r-acrt")
    (version "1.0.1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "acrt" version))
       (sha256
        (base32
         "0y9ndcq8ffpfrv7w9rikm4zn68jpsj6baqisq9kp2433xrwzdb6s"))))
    (properties `((upstream-name . "acrt")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-rcpp" ,r-rcpp)
       ("r-rcppeigen" ,r-rcppeigen)
       ("r-sandwich" ,r-sandwich)))
    (home-page "https://cran.r-project.org/web/packages/acrt/")
    (synopsis "Autocorrelation robust testing")
    (description
     "This package provides functions for testing affine hypotheses on the
regression coefficient vector in regression models with autocorrelated
errors.")
    (license license:gpl2)))

(define-public r-acs
  (package
    (name "r-acs")
    (version "2.1.4")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "acs" version))
       (sha256
        (base32
         "0ajw9rf8l8akcvgqvbxjvryc6wjx74521xyxswz2b0bky3m6kah5"))))
    (properties `((upstream-name . "acs")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-httr" ,r-httr)
       ("r-plyr" ,r-plyr)
       ("r-rcpp" ,r-rcpp)
       ("r-stringr" ,r-stringr)
       ("r-xml" ,r-xml)))
    (home-page "https://dusp.mit.edu/faculty/ezra-haber-glenn")
    (synopsis "Work with data from the US Census")
    (description
     "This package provides a general toolkit for downloading, managing,
analyzing, and presenting data from the
@url{https://www.census.gov/data/developers/data-sets.html, U.S.  Census},
including SF1 (Decennial short-form), SF3 (Decennial long-form), and the
American Community Survey (ACS).  Confidence intervals provided with ACS data
are converted to standard errors to be bundled with estimates in complex
@code{acs} objects.  The package provides new methods to conduct standard
operations on @code{acs} objects and present/plot data in statistically
appropriate ways.")
    (license license:gpl3)))

(define-public r-acss-data
  (package
    (name "r-acss-data")
    (version "1.0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "acss.data" version))
       (sha256
        (base32
         "09kl4179ipr8bq19g89xcdi1xxs397zcx5cvgp6viy8gn687ilgv"))))
    (properties `((upstream-name . "acss.data")))
    (build-system r-build-system)
    (home-page "http://complexitycalculator.com/methodology.html")
    (synopsis "Data for algorithmic complexity of short strings")
    (description
     "This is a data only package providing the algorithmic complexity of
short strings, computed using the coding theorem method.  For a given set of
symbols in a string, all possible or a large number of random samples of
Turing machines with a given number of states (e.g., 5) and number of symbols
corresponding to the number of symbols in the strings were simulated until
they reached a halting state or failed to end.  This package contains data on
4.5 million strings from length 1 to 12 simulated on Turing machines with 2,
4, 5, 6, and 9 symbols.  The complexity of the string corresponds to the
distribution of the halting states.")
    (license license:gpl2+)))

(define-public r-acss
  (package
    (name "r-acss")
    (version "0.2-5")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "acss" version))
       (sha256
        (base32
         "0cqa60544f58l5qd7h6xmsir40b9hqnq6pqgd5hfx2j2l5n7qhmk"))))
    (properties `((upstream-name . "acss")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-acss-data" ,r-acss-data)
       ("r-zoo" ,r-zoo)))
    (home-page "http://complexitycalculator.com/methodology.html")
    (synopsis "Algorithmic complexity for short strings")
    (description
     "The main purpose of this package is to provide the algorithmic
complexity for short strings, an approximation of the Kolmogorov Complexity of
a short string using the coding theorem method.  While the database containing
the complexity is provided in the data only package @code{acss.data}, this
package provides functions accessing the data such as @code{prob_random}
returning the posterior probability that a given string was produced by a
random process.  In addition, two traditional (but problematic) measures of
complexity are also provided: entropy and change complexity.")
    (license license:gpl2+)))

(define-public r-acswr
  (package
    (name "r-acswr")
    (version "1.0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "ACSWR" version))
       (sha256
        (base32
         "195vjrkang5cl7gwsna0aq4p0h4jym9xg9yh94bnf8vq6wf8j83n"))))
    (properties `((upstream-name . "ACSWR")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-mass" ,r-mass)))
    (home-page "https://cran.r-project.org/web/packages/ACSWR/")
    (synopsis "Companion package for the book \"A Course in Statistics with R\"")
    (description
     "This is a companion package for the book \"A Course in Statistics with
R\" (ISBN 978-1-119-15272-9.)")
    (license license:gpl2)))

(define-public r-alabama
  (package
    (name "r-alabama")
    (version "2015.3-1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "alabama" version))
       (sha256
        (base32
         "0mlgk929gdismikwx4k2ndqq57nnqj7mlgvd3479b214hksgq036"))))
    (properties `((upstream-name . "alabama")))
    (build-system r-build-system)
    (propagated-inputs `(("r-numderiv" ,r-numderiv)))
    (home-page "https://cran.r-project.org/web/packages/alabama/")
    (synopsis "Constrained nonlinear optimization")
    (description
     "Alabama stands for Augmented Lagrangian Adaptive Barrier Minimization
Algorithm; it is used for optimizing smooth nonlinear objective functions with
constraints.  Linear or nonlinear equality and inequality constraints are
allowed.")
    (license license:gpl2+)))

(define-public r-gdina
  (package
    (name "r-gdina")
    (version "2.7.9")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "GDINA" version))
       (sha256
        (base32
         "13pmj069r04h38hg61ibyn1ab15zdy9m0qv60vi25ahgsmg6ccvx"))))
    (properties `((upstream-name . "GDINA")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-alabama" ,r-alabama)
       ("r-ggplot2" ,r-ggplot2)
       ("r-mass" ,r-mass)
       ("r-nloptr" ,r-nloptr)
       ("r-numderiv" ,r-numderiv)
       ("r-rcpp" ,r-rcpp)
       ("r-rcpparmadillo" ,r-rcpparmadillo)
       ("r-rsolnp" ,r-rsolnp)
       ("r-shiny" ,r-shiny)
       ("r-shinydashboard" ,r-shinydashboard)))
    (home-page "https://github.com/Wenchao-Ma/GDINA")
    (synopsis "Generalized DINA model framework")
    (description
     "This package provides a set of psychometric tools for cognitive
diagnosis modeling based on the generalized deterministic inputs, noisy and
gate (G-DINA) model by de la Torre (2011) @url{doi:10.1007/s11336-011-9207-7}
and its extensions, including the sequential G-DINA model by Ma and de la
Torre (2016) @url{doi:10.1111/bmsp.12070} for polytomous responses, and the
polytomous G-DINA model by Chen and de la Torre
@url{doi:10.1177/0146621613479818} for polytomous attributes.  Joint attribute
distribution can be independent, saturated, higher-order, loglinear smoothed
or structured.  Q-matrix validation, item and model fit statistics, model
comparison at test and item level and differential item functioning can also
be conducted.  A graphical user interface is also provided.")
    (license license:gpl3)))

(define-public r-actcd
  (package
    (name "r-actcd")
    (version "1.2-0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "ACTCD" version))
       (sha256
        (base32
         "0mzjxxr2zfdidw8ibh6w8mvpkw3q3nvngqi05g9ind26ckvk053p"))))
    (properties `((upstream-name . "ACTCD")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-gdina" ,r-gdina)
       ("r-r-methodss3" ,r-r-methodss3)))
    (native-inputs
     `(("gfortran" ,gfortran)))
    (home-page "https://cran.r-project.org/web/packages/ACTCD/")
    (synopsis "Asymptotic classification theory for cognitive diagnosis")
    (description
     "This is a package supporting cluster analysis for cognitive diagnosis
based on the Asymptotic Classification Theory (Chiu, Douglas & Li, 2009;
@url{doi:10.1007/s11336-009-9125-0}).  Given the sample statistic of
sum-scores, cluster analysis techniques can be used to classify examinees into
latent classes based on their attribute patterns.  In addition to the
algorithms used to classify data, three labeling approaches are proposed to
label clusters so that examinees' attribute profiles can be obtained.")
    (license license:gpl2+)))

(define-public r-ineq
  (package
    (name "r-ineq")
    (version "0.2-13")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "ineq" version))
       (sha256
        (base32
         "09fsxyrh0j7mwmb5hkhmrzgcy7kf85jxkh7zlwpgqgcsyl1n91z0"))))
    (properties `((upstream-name . "ineq")))
    (build-system r-build-system)
    (home-page "https://cran.r-project.org/web/packages/ineq/")
    (synopsis "Measuring inequality, concentration, and poverty")
    (description
     "This package provides tools for measuring inequality, concentration, and
poverty measures.  It provides both empirical and theoretical Lorenz curves.")
    ;; Either of these two versions.
    (license (list license:gpl2 license:gpl3))))

(define-public r-actfrag
  (package
    (name "r-actfrag")
    (version "0.1.1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "ActFrag" version))
       (sha256
        (base32
         "08r3gwjz4fkyy85dxqix0ffm5xyq45032qv3snnzxnlqxslxbqn1"))))
    (properties `((upstream-name . "ActFrag")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-accelerometry" ,r-accelerometry)
       ("r-dplyr" ,r-dplyr)
       ("r-ineq" ,r-ineq)
       ("r-survival" ,r-survival)
       ("r-tidyr" ,r-tidyr)))
    (home-page "https://github.com/junruidi/ActFrag")
    (synopsis "Activity fragmentation metrics extraction")
    (description
     "This package provides functions to extract commonly used fragmentation
metrics to quantify time accumulation strategies based on minute level
actigraphy-measured activity counts data.")
    (license license:gpl3)))

(define-public r-fda
  (package
    (name "r-fda")
    (version "2.4.8.1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "fda" version))
       (sha256
        (base32
         "0g50kj1dx7zarjv0lgwyzd2c7bv6di7nkndmywday5vjywgl8m7a"))))
    (properties `((upstream-name . "fda")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-matrix" ,r-matrix)))
    (home-page "https://www.functionaldata.org")
    (synopsis "Functional data analysis")
    (description
     "These functions were developed to support functional data analysis as
described in Ramsay, J. O. and Silverman, B. W. (2005) Functional Data
Analysis.  The package includes data sets and script files working many
examples.")
    (license license:gpl2+)))

(define-public r-actigraphy
  (package
    (name "r-actigraphy")
    (version "1.4.0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "Actigraphy" version))
       (sha256
        (base32
         "0bpmvszzv5fm72nar3wgnmfl5am7znqfajmlbv38ihkbi7jbwk20"))))
    (properties `((upstream-name . "Actigraphy")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-fda" ,r-fda)))
    (home-page "https://cran.r-project.org/web/packages/Actigraphy/")
    (synopsis "Actigraphy data analysis")
    (description
     "This package provides tools for functional linear modeling and analysis
of actigraphy data.")
    (license license:asl2.0)))

(define-public r-activedriver
  (package
    (name "r-activedriver")
    (version "1.0.0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "ActiveDriver" version))
       (sha256
        (base32
         "10c7ga48fwvpd5mc4dqiyw4kc2l0iz5qn4hg7xk15r1qmm5rsipa"))))
    (properties `((upstream-name . "ActiveDriver")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-mass" ,r-mass)))
    (home-page "https://cran.r-project.org/web/packages/ActiveDriver/")
    (synopsis "Tools for finding cancer driver proteins")
    (description
     "This package provides a mutation analysis tool that discovers cancer
driver genes with frequent mutations in protein signalling sites such as
post-translational modifications (phosphorylation, ubiquitination, etc).  The
Poisson generalized linear regression model identifies genes where cancer
mutations in signalling sites are more frequent than expected from the
sequence of the entire gene.  Integration of mutations with signalling
information helps find new driver genes and propose candidate mechanisms to
known drivers.")
    (license license:gpl2+)))

(define-public r-activitycounts
  (package
    (name "r-activitycounts")
    (version "0.1.2")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "activityCounts" version))
       (sha256
        (base32
         "0zgxr2sk3a8kmygfxx1p5hnrfwdkxx7php6jlrhm8wv6052ck8jz"))))
    (properties
     `((upstream-name . "activityCounts")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-lubridate" ,r-lubridate)
       ("r-magrittr" ,r-magrittr)
       ("r-seewave" ,r-seewave)
       ("r-signal" ,r-signal)
       ("r-tibble" ,r-tibble)))
    (home-page "https://github.com/walkabillylab/activityCounts")
    (synopsis "Generate ActiLife counts")
    (description
     "ActiLife generates activity counts from data collected by Actigraph
accelerometers.  Actigraph is one of the most common research-grade
accelerometers.  There is considerable research validating and developing
algorithms for human activity using ActiLife counts.  Unfortunately, ActiLife
counts are proprietary and difficult to implement if researchers use different
accelerometer brands.  The code creates ActiLife counts from raw acceleration
data for different accelerometer brands.")
    (license license:gpl3)))

(define-public r-activityindex
  (package
    (name "r-activityindex")
    (version "0.3.6")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "ActivityIndex" version))
       (sha256
        (base32
         "14k6d78s15j7kb7jhixf4msrdjdl28d0r264cbvy41p8dkq7ysvk"))))
    (properties `((upstream-name . "ActivityIndex")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-data-table" ,r-data-table)
       ("r-matrixstats" ,r-matrixstats)
       ("r-r-utils" ,r-r-utils)))
    (home-page "https://cran.r-project.org/web/packages/ActivityIndex/")
    (synopsis "Activity Index calculation using raw accelerometry data")
    (description
     "This is a package to read raw accelerometry from GT3X+ accelerometry
data and plain table data to calculate the Activity Index from Bai et
al. (2016) @url{doi:10.1371/journal.pone.0160644}.")
    (license license:gpl3)))

(define-public r-activpal
  (package
    (name "r-activpal")
    (version "0.1.3")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "activPAL" version))
       (sha256
        (base32
         "1h6hp5z89ji73gdzxy1dgbfwjysiy5lvcqh90xagpb7sa7ahs3na"))))
    (properties `((upstream-name . "activPAL")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-devtools" ,r-devtools)
       ("r-dplyr" ,r-dplyr)
       ("r-ggplot2" ,r-ggplot2)
       ("r-lubridate" ,r-lubridate)
       ("r-magrittr" ,r-magrittr)
       ("r-tidyr" ,r-tidyr)))
    (home-page "https://cran.r-project.org/web/packages/activPAL")
    (synopsis "Processing and chart generation from activPAL events files")
    (description
     "This package contains functions to generate pre-defined summary
statistics from activPAL events files.  The package also contains functions to
produce informative graphics that visualize physical activity behaviour and
trends.  This includes generating graphs that align physical activity
behaviour with additional time based observations described by other data
sets, such as sleep diaries and continuous glucose monitoring data.")
    (license license:gpl3)))

(define-public r-activpalprocessing
  (package
    (name "r-activpalprocessing")
    (version "1.0.2")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "activpalProcessing" version))
       (sha256
        (base32
         "1y0bjx2qx53iy930y9iww4q1yzjj8y16cwgixk1mq3w4g1f116d1"))))
    (properties
     `((upstream-name . "activpalProcessing")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-chron" ,r-chron)))
    (home-page "https://cran.r-project.org/web/packages/activpalProcessing/")
    (synopsis "Process activPAL events files")
    (description
     "This package performs estimation of physical activity and sedentary
behavior variables from activPAL events files.")
    ;; Either version of the GPL.
    (license (list license:gpl2 license:gpl3))))

(define-public r-actogrammr
  (package
    (name "r-actogrammr")
    (version "0.2.3")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "actogrammr" version))
       (sha256
        (base32
         "1jzvarmd41yqlrkagzlc8m19n5mn0w0b36fy50lyvgrfsafjfbqa"))))
    (properties `((upstream-name . "actogrammr")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-dplyr" ,r-dplyr)
       ("r-ggplot2" ,r-ggplot2)
       ("r-lubridate" ,r-lubridate)
       ("r-readr" ,r-readr)
       ("r-tidyr" ,r-tidyr)))
    (home-page "https://cran.r-project.org/web/packages/actogrammr/")
    (synopsis "Read in activity data and plot actograms")
    (description
     "Read in activity measurements from standard file formats used by
circadian rhythm researchers, currently only ClockLab format, and process and
plot the data.  The central type of plot is the actogram, as first described
in \"Activity and distribution of certain wild mice in relation to biotic
communities\" by MS Johnson (1926) @url{doi:10.2307/1373575}.")
    (license license:gpl3)))

(define-public r-expint
  (package
    (name "r-expint")
    (version "0.1-6")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "expint" version))
       (sha256
        (base32
         "0iai25cglcdnf44d2d1fz1xpw4q600my4zq4493fk4cs5673mlf7"))))
    (properties `((upstream-name . "expint")))
    (build-system r-build-system)
    (home-page "https://gitlab.com/vigou3/expint")
    (synopsis "Exponential integral and incomplete Gamma function")
    (description
     "This package provides the exponential integrals @code{E_1(x)},
@code{E_2(x)}, @code{E_n(x)} and @code{Ei(x)}, and the incomplete gamma
function @code{G(a, x)} defined for negative values of its first argument.
The package also gives easy access to the underlying C routines through an
API; see the package vignette for details.")
    (license license:gpl2+)))

(define-public r-actuar
  (package
    (name "r-actuar")
    (version "2.3-3")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "actuar" version))
       (sha256
        (base32
         "0aw3hlan5y22mdqk1wvnw9ksqhwp4yy5hi0dpv21p7s0hyxhphih"))))
    (properties `((upstream-name . "actuar")))
    (build-system r-build-system)
    (propagated-inputs `(("r-expint" ,r-expint)))
    (home-page "https://gitlab.com/vigou3/actuar")
    (synopsis "Actuarial functions and heavy tailed distributions")
    (description
     "This package provides functions and data sets for actuarial science:
modeling of loss distributions; risk theory and ruin theory; simulation of
compound models, discrete mixtures and compound hierarchical models;
credibility theory.  It boasts support for many additional probability
distributions to model insurance loss amounts and loss frequency: 19
continuous heavy tailed distributions; the Poisson-inverse Gaussian discrete
distribution; zero-truncated and zero-modified extensions of the standard
discrete distributions.  It also supports phase-type distributions commonly
used to compute ruin probabilities.")
    (license license:gpl2+)))

(define-public r-bmp
  (package
    (name "r-bmp")
    (version "0.3")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "bmp" version))
       (sha256
        (base32
         "0jd67r11bn98hjwgyr6gas423787xy7ji2hq7ay80blkkcj91xxx"))))
    (properties `((upstream-name . "bmp")))
    (build-system r-build-system)
    (home-page "https://cran.r-project.org/web/packages/bmp/")
    (synopsis "Read Bitmap (BMP) images")
    (description
     "This package provides pure R tools to read BMP format images.  It is
currently limited to 8 bit greyscale images and 24, 32 bit (A)RGB images.")
    (license license:gpl2+)))

(define-public r-readbitmap
  (package
    (name "r-readbitmap")
    (version "0.1.5")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "readbitmap" version))
       (sha256
        (base32
         "14825906l326w59g6apy00j55jg3h5kx2r6s031f4gdkbrc7szbk"))))
    (properties `((upstream-name . "readbitmap")))
    (build-system r-build-system)
    (inputs
     `(("libjpeg" ,libjpeg)
       ("libpng" ,libpng)))
    (propagated-inputs
     `(("r-bmp" ,r-bmp)
       ("r-jpeg" ,r-jpeg)
       ("r-png" ,r-png)
       ("r-tiff" ,r-tiff)))
    (home-page "https://github.com/jefferis/readbitmap")
    (synopsis "Unified interface to read bitmap images (BMP, JPEG, PNG, TIFF)")
    (description
     "This package provides tools to identify and read BMP, JPEG, PNG, and
TIFF format bitmap images.  Identification defaults to the use of the magic
number embedded in the file rather than the file extension.")
    (license license:gpl2+)))

(define-public r-imager
  (package
    (name "r-imager")
    (version "0.42.1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "imager" version))
       (sha256
        (base32
         "1d7a49lcna77wyfjf5q1b89jck3p3vnysnkgz4drb0qkpy6hz76b"))))
    (properties `((upstream-name . "imager")))
    (build-system r-build-system)
    (inputs
     `(("fftw" ,fftw)
       ("libtiff" ,libtiff)
       ("libx11" ,libx11)
       ("zlib" ,zlib)))
    (propagated-inputs
     `(("r-downloader" ,r-downloader)
       ("r-igraph" ,r-igraph)
       ("r-jpeg" ,r-jpeg)
       ("r-magrittr" ,r-magrittr)
       ("r-png" ,r-png)
       ("r-purrr" ,r-purrr)
       ("r-rcpp" ,r-rcpp)
       ("r-readbitmap" ,r-readbitmap)
       ("r-stringr" ,r-stringr)))
    (native-inputs `(("pkg-config" ,pkg-config)))
    (home-page "https://dahtah.github.io/imager/")
    (synopsis "Image processing library")
    (description
     "This is a package for fast image processing for images in up to 4
dimensions (two spatial dimensions, one time/depth dimension, one color
dimension).  It provides most traditional image processing tools (filtering,
morphology, transformations, etc.) as well as various functions for easily
analyzing image data using R.  The package wraps @url{http://cimg.eu, CImg}, a
simple, modern C++ library for image processing.")
    (license license:lgpl3)))

(define-public r-acuityview
  (package
    (name "r-acuityview")
    (version "0.1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "AcuityView" version))
       (sha256
        (base32
         "0f0iclmnwdc8ixiiai4svk4x1g3pjy7dhm3cm58fv6ckx12d3d2l"))))
    (properties `((upstream-name . "AcuityView")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-fftwtools" ,r-fftwtools)
       ("r-imager" ,r-imager)
       ("r-plotrix" ,r-plotrix)))
    (home-page "https://cran.r-project.org/web/packages/AcuityView/")
    (synopsis "Display scenes as seen by an animal with less acute vision")
    (description
     "This package provides a simple method for representing a visual scene as
it may be seen by an animal with less acute vision.")
    (license license:gpl2+)))

(define-public r-caret
  (package
    (name "r-caret")
    (version "6.0-86")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "caret" version))
       (sha256
        (base32
         "0dyflixdw98lvk2x3w136sw24ij0fwx5c7l709dmqr5z7xy1qjns"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-foreach" ,r-foreach)
       ("r-ggplot2" ,r-ggplot2)
       ("r-lattice" ,r-lattice)
       ("r-modelmetrics" ,r-modelmetrics)
       ("r-nlme" ,r-nlme)
       ("r-plyr" ,r-plyr)
       ("r-proc" ,r-proc)
       ("r-recipes" ,r-recipes)
       ("r-reshape2" ,r-reshape2)
       ("r-withr" ,r-withr)))
    (native-inputs
     `(("r-knitr" ,r-knitr)))
    (home-page "https://github.com/topepo/caret")
    (synopsis "Classification and regression training")
    (description
     "This package provides miscellaneous functions for training and plotting
classification and regression models.")
    (license license:gpl2+)))

(define-public r-adabag
  (package
    (name "r-adabag")
    (version "4.2")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "adabag" version))
       (sha256
        (base32
         "109wrl1pwvmyv2l909hrvk7dg4aa9pv449mvdycp50zwrsw9w0a7"))))
    (properties `((upstream-name . "adabag")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-caret" ,r-caret)
       ("r-doparallel" ,r-doparallel)
       ("r-foreach" ,r-foreach)
       ("r-rpart" ,r-rpart)))
    (home-page "https://cran.r-project.org/web/packages/adabag/")
    (synopsis "Multiclass AdaBoost.M1, SAMME and Bagging")
    (description
     "This package implements Freund and Schapire's Adaboost.M1 algorithm and
Breiman's Bagging algorithm using classification trees as individual
classifiers.  Once these classifiers have been trained, they can be used to
predict on new data.  Also, cross validation estimation of the error can be
done.")
    (license license:gpl2+)))

(define-public r-adagio
  (package
    (name "r-adagio")
    (version "0.7.1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "adagio" version))
       (sha256
        (base32
         "1h9l0ddrxq8y35iy9hdkxdvdwsqpnpkzzbkbwwhm4380lq1m7a3k"))))
    (properties `((upstream-name . "adagio")))
    (build-system r-build-system)
    (native-inputs `(("gfortran" ,gfortran)))
    (home-page "https://cran.r-project.org/web/packages/adagio/")
    (synopsis "Discrete and global optimization routines")
    (description
     "This package provides methods and algorithms for discrete optimization,
e.g. knapsack and subset sum procedures, derivative-free Nelder-Mead and
Hooke-Jeeves minimization, and some (evolutionary) global optimization
functions.")
    (license license:gpl3+)))

(define-public r-univoutl
  (package
    (name "r-univoutl")
    (version "0.1-5")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "univOutl" version))
       (sha256
        (base32
         "193wrpkvgmlrx43nag8w3ivrlqm37nm6g86wcvd3bgw3hchs70gi"))))
    (properties `((upstream-name . "univOutl")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-hmisc" ,r-hmisc)
       ("r-robustbase" ,r-robustbase)))
    (home-page "https://github.com/marcellodo/univOutl")
    (synopsis "Detection of univariate outliers")
    (description
     "This package provides well-known outlier detection techniques in the
univariate case.  Methods to deal with skewed distribution are included too.
The Hidiroglou-Berthelot (1986) method to search for outliers in ratios of
historical data is implemented as well.  When available, survey weights can be
used in outliers detection.")
    (license license:gpl2+)))

(define-public r-tolerance
  (package
    (name "r-tolerance")
    (version "2.0.0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "tolerance" version))
       (sha256
        (base32
         "001snzr2ipag3zprynydlbi9prkjzrllc054qh7m0qwkb3r19jjd"))))
    (properties `((upstream-name . "tolerance")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-mass" ,r-mass)
       ("r-rgl" ,r-rgl)))
    (home-page "https://cran.r-project.org/web/packages/tolerance/")
    (synopsis "Statistical tolerance intervals and regions")
    (description
     "This package provides functions for estimating tolerance
limits (intervals) for various univariate distributions (binomial, Cauchy,
discrete Pareto, exponential, two-parameter exponential, extreme value,
hypergeometric, Laplace, logistic, negative binomial, negative hypergeometric,
normal, Pareto, Poisson-Lindley, Poisson, uniform, and Zipf-Mandelbrot),
Bayesian normal tolerance limits, multivariate normal tolerance regions,
nonparametric tolerance intervals, tolerance bands for regression
settings (linear regression, nonlinear regression, nonparametric regression,
and multivariate regression), and analysis of variance tolerance intervals.
Visualizations are also available for most of these settings.")
    (license license:gpl2+)))

(define-public r-additivitytests
  (package
    (name "r-additivitytests")
    (version "1.1-4")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "additivityTests" version))
       (sha256
        (base32
         "048ds90wqjdjy1nyhna3m06asdklbh8sx1n556kss2j1r1pma1sw"))))
    (properties
     `((upstream-name . "additivityTests")))
    (build-system r-build-system)
    (home-page "https://github.com/simecek/additivityTests")
    (synopsis "Additivity tests in the two way Anova with single sub-class numbers")
    (description
     "This package provides an implementation of the Tukey, Mandel,
Johnson-Graybill, LBI, Tusell and modified Tukey non-additivity tests.")
    (license license:gpl3)))

(define-public r-flexclust
  (package
    (name "r-flexclust")
    (version "1.4-0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "flexclust" version))
       (sha256
        (base32
         "0x7wxk8y46ndyz6fdacym0rd6p9wh3pcfr28chjcg5d7fm849zl2"))))
    (properties `((upstream-name . "flexclust")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-class" ,r-class)
       ("r-lattice" ,r-lattice)
       ("r-modeltools" ,r-modeltools)))
    (home-page "https://cran.r-project.org/web/packages/flexclust/")
    (synopsis "Flexible cluster algorithms")
    (description
     "The main function @code{kcca} implements a general framework for
k-centroids cluster analysis supporting arbitrary distance measures and
centroid computation.  Further cluster methods include hard competitive
learning, neural gas, and QT clustering.  There are numerous visualization
methods for cluster results (neighborhood graphs, convex cluster hulls,
barcharts of centroids, ...), and bootstrap methods for the analysis of
cluster stability.")
    (license license:gpl2)))

(define-public r-biclust
  (package
    (name "r-biclust")
    (version "2.0.2")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "biclust" version))
       (sha256
        (base32
         "1pk7mvwlg4hkc4cn4w6wr2c192qx03d1xfwlzclk5bw1nmcg483b"))))
    (properties `((upstream-name . "biclust")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-additivitytests" ,r-additivitytests)
       ("r-colorspace" ,r-colorspace)
       ("r-flexclust" ,r-flexclust)
       ("r-ggplot2" ,r-ggplot2)
       ("r-lattice" ,r-lattice)
       ("r-mass" ,r-mass)
       ("r-tidyr" ,r-tidyr)))
    (home-page "https://cran.r-project.org/web/packages/biclust/")
    (synopsis "BiCluster algorithms")
    (description
     "The main function @code{biclust()} provides several algorithms to find
biclusters in two-dimensional data, spectral, plaid model, xmotifs, and bimax.
In addition, the package provides methods for data
preprocessing (normalization and discretization), visualization, and
validation of bicluster solutions.")
    (license license:gpl3)))

(define-public r-icge
  (package
    (name "r-icge")
    (version "0.3")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "ICGE" version))
       (sha256
        (base32
         "0xin7zml1nbygyi08hhg3wwr2jr1zcsvrlgia89zp4xanxlzgaqa"))))
    (properties `((upstream-name . "ICGE")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-cluster" ,r-cluster)
       ("r-mass" ,r-mass)))
    (home-page "https://cran.r-project.org/web/packages/ICGE/")
    (synopsis "Cluster estimation and identification of atypical units")
    (description
     "ICGE is a package that helps to estimate the number of real clusters in
data as well as to identify atypical units.  The underlying methods are based
on distances rather than on unit x variables.")
    (license license:gpl2+)))

(define-public r-depth
  (package
    (name "r-depth")
    (version "2.1-1.1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "depth" version))
       (sha256
        (base32
         "0szy0027nh4ps1z919i740i50app5q7cfyg1fj7pdyl45nbl8k6m"))))
    (properties `((upstream-name . "depth")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-abind" ,r-abind)
       ("r-circular" ,r-circular)
       ("r-rgl" ,r-rgl)))
    (native-inputs
     `(("gfortran" ,gfortran)))
    (home-page "https://cran.r-project.org/web/packages/depth/")
    (synopsis "Nonparametric depth functions for multivariate analysis")
    (description
     "This package provides tools for depth functions methodology applied to
multivariate analysis.  Besides allowing calculation of depth values and
depth-based location estimators, the package includes functions or drawing
contour plots and perspective plots of depth functions.  Euclidian and
spherical depths are supported.")
    (license license:gpl2)))

(define-public r-archetypes
  (package
    (name "r-archetypes")
    (version "2.2-0.1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "archetypes" version))
       (sha256
        (base32
         "0ibxsr173ib77gjhid91m85s8gjii4mi2w3d52q5301igv20p7r0"))))
    (properties `((upstream-name . "archetypes")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-modeltools" ,r-modeltools)
       ("r-nnls" ,r-nnls)))
    (home-page "https://cran.r-project.org/web/packages/archetypes")
    (synopsis "Archetypal analysis")
    (description
     "The main function @code{archetypes} implements a framework for
archetypal analysis supporting arbitrary problem solving mechanisms for the
different conceptual parts of the algorithm.")
    (license license:gpl2+)))

(define-public r-shapes
  (package
    (name "r-shapes")
    (version "1.2.5")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "shapes" version))
       (sha256
        (base32
         "0gfpdydfysp5mwg7qmkn73s67gvh2szb40mzqrx97h41ijgcgd8s"))))
    (properties `((upstream-name . "shapes")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-mass" ,r-mass)
       ("r-minpack-lm" ,r-minpack-lm)
       ("r-rgl" ,r-rgl)
       ("r-scatterplot3d" ,r-scatterplot3d)))
    (home-page "http://www.maths.nottingham.ac.uk/~ild/shapes")
    (synopsis "Statistical shape analysis")
    (description
     "This package provides routines for the statistical analysis of landmark
shapes, including Procrustes analysis, graphical displays, principal
components analysis, permutation and bootstrap tests, thin-plate spline
transformation grids and comparing covariance matrices.  See Dryden, I.L.  and
Mardia, K.V. (2016).  Statistical shape analysis, with Applications in R (2nd
Edition), John Wiley and Sons.")
    (license license:gpl2)))

(define-public r-anthropometry
  (package
    (name "r-anthropometry")
    (version "1.13")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "Anthropometry" version))
       (sha256
        (base32
         "1f568ri1s6psaby8y737vrkarbjg64v89d4jyw23hy17apdmszr8"))))
    (properties `((upstream-name . "Anthropometry")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-archetypes" ,r-archetypes)
       ("r-biclust" ,r-biclust)
       ("r-cluster" ,r-cluster)
       ("r-depth" ,r-depth)
       ("r-fnn" ,r-fnn)
       ("r-icge" ,r-icge)
       ("r-nnls" ,r-nnls)
       ("r-rgl" ,r-rgl)
       ("r-shapes" ,r-shapes)))
    (home-page "https://cran.r-project.org/web/packages/Anthropometry/")
    (synopsis "Statistical methods for anthropometric data")
    (description
     "This package provides statistical methods especially developed to
analyze anthropometric data.  These methods are aimed at providing effective
solutions to some commons problems related to Ergonomics and Anthropometry.
They are based on clustering, the statistical concept of data depth,
statistical shape analysis and archetypal analysis.")
    (license license:gpl2+)))

(define-public r-adamethods
  (package
    (name "r-adamethods")
    (version "1.2")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "adamethods" version))
       (sha256
        (base32
         "0mp73zh5x6h18gv29v981kb9n632kb58lvlcxwr6vcvrx393nrxh"))))
    (properties `((upstream-name . "adamethods")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-anthropometry" ,r-anthropometry)
       ("r-archetypes" ,r-archetypes)
       ("r-fnn" ,r-fnn)
       ("r-foreach" ,r-foreach)
       ("r-nnls" ,r-nnls)
       ("r-tolerance" ,r-tolerance)
       ("r-univoutl" ,r-univoutl)))
    (home-page "https://cran.r-project.org/web/packages/adamethods/")
    (synopsis "Archetypoid algorithms and anomaly detection")
    (description
     "This package is a collection of several algorithms to obtain
archetypoids with small and large databases and with both classical
multivariate data and functional data (univariate and multivariate).  Some of
these algorithms also allow to detect anomalies (outliers).")
    (license license:gpl2+)))

(define-public r-idpmisc
  (package
    (name "r-idpmisc")
    (version "1.1.20")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "IDPmisc" version))
       (sha256
        (base32
         "0zy6mxqa8arq0vvhsdcifzm3085c23rnwa1n36fhircph1xwvfdw"))))
    (properties `((upstream-name . "IDPmisc")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-lattice" ,r-lattice)))
    (home-page "https://cran.r-project.org/web/packages/IDPmisc/")
    (synopsis "Functions for data analyses and visualization")
    (description
     "This package provides different high-level graphics functions for
displaying large datasets, displaying circular data in a very flexible way,
finding local maxima, brewing color ramps, drawing nice arrows, zooming
2D-plots, creating figures with differently colored margin and plot region.
In addition, the package contains auxiliary functions for data manipulation
like omitting observations with irregular values or selecting data by logical
vectors, which include NAs.  Other functions are especially useful in
spectroscopy and analyses of environmental data: robust baseline fitting,
finding peaks in spectra, converting humidity measures.")
    (license license:gpl3+)))

(define-public r-qqman
  (package
    (name "r-qqman")
    (version "0.1.4")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "qqman" version))
       (sha256
        (base32
         "1v9s9ag1hfb47py87wb2nad4mbsfx35832hdmrh5kxrb2f11zl1s"))))
    (properties `((upstream-name . "qqman")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-calibrate" ,r-calibrate)))
    (home-page "https://cran.r-project.org/web/packages/qqman/")
    (synopsis "Q-Q and Manhattan plots for GWAS data")
    (description
     "This package allows you to create Q-Q and Manhattan plots for GWAS data
from PLINK results.")
    (license license:gpl3)))

(define-public r-ggplot-multistats
  (package
    (name "r-ggplot-multistats")
    (version "1.0.0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "ggplot.multistats" version))
       (sha256
        (base32
         "1afzfa86vc484bcwpg7m1ky03jpax584rigzgai8w06pifkmz0il"))))
    (properties
     `((upstream-name . "ggplot.multistats")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-ggplot2" ,r-ggplot2)
       ("r-hexbin" ,r-hexbin)
       ("r-rlang" ,r-rlang)
       ("r-scales" ,r-scales)))
    (home-page "https://github.com/flying-sheep/ggplot.multistats")
    (synopsis "Multiple summary statistics for binned stats/geometries")
    (description
     "This package provides the ggplot binning layer @code{stat_summaries_hex()},
which functions similar to its singular form, but allows the use of multiple
statistics per bin.  Those statistics can be mapped to multiple bin
aesthetics.")
    (license license:gpl3)))

(define-public r-knn-covertree
  (package
    (name "r-knn-covertree")
    (version "1.0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "knn.covertree" version))
       (sha256
        (base32
         "0msfcmwydws7q7m5jdb0dxab0nkbl7mq5llg6v3r4qrnlvrdggvz"))))
    (properties `((upstream-name . "knn.covertree")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-matrix" ,r-matrix)
       ("r-rcpp" ,r-rcpp)
       ("r-rcppeigen" ,r-rcppeigen)))
    (home-page "https://github.com/flying-sheep/knn.covertree")
    (synopsis "Accurate kNN Implementation with multiple distance measures")
    (description
     "Similarly to the FNN package, this package allows calculation of the k
nearest neighbors (kNN) of a data matrix.  The implementation is based on
cover trees introduced by Alina Beygelzimer, Sham Kakade, and John
Langford (2006) @url{doi:10.1145/1143844.1143857}.")
    (license license:agpl3+)))

(define-public r-poibin
  (package
    (name "r-poibin")
    (version "1.5")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "poibin" version))
       (sha256
        (base32
         "1sxryvwwz6ldsnkzdy56p8c895s5yvpcai9ndyjv1x5q3l05wf9v"))))
    (properties `((upstream-name . "poibin")))
    (build-system r-build-system)
    (home-page "https://cran.r-project.org/web/packages/poibin/")
    (synopsis "Poisson binomial distribution")
    (description
     "This package provides an implementation of both the exact and
approximation methods for computing the @dfn{cumulative distribution
function} (CDF) of the Poisson binomial distribution.  It also provides the
@dfn{probability mass function} (PMF), quantile function, and random number
generation for the Poisson binomial distribution.")
    (license license:gpl2)))

(define-public r-diagram
  (package
    (name "r-diagram")
    (version "1.6.4")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "diagram" version))
       (sha256
        (base32
         "0f6ffprn5k0ir1s7m9s7izc64aa17r3gnygagz5bihrlsvawaavw"))))
    (properties `((upstream-name . "diagram")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-shape" ,r-shape)))
    (home-page "https://cran.r-project.org/web/packages/diagram/")
    (synopsis "Visualize simple graphs (networks) and plot flow diagrams")
    (description
     "This package provides tools to visualize simple graphs (networks) based
on a transition matrix, utilities to plot flow diagrams, visualizing webs,
electrical networks, etc.  It also includes supporting material for the book
\"A practical guide to ecological modelling - using R as a simulation
platform\" by Karline Soetaert and Peter M.J. Herman (2009) and the book
\"Solving Differential Equations in R\" by Karline Soetaert, Jeff Cash and
Francesca Mazzia (2012).")
    (license license:gpl2+)))

(define-public r-lim
  (package
    (name "r-lim")
    (version "1.4.6")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "LIM" version))
       (sha256
        (base32
         "03x1gnm06bw1wrzc01110bjzd2mvjdzbc2mbrazh22jrmb32w5d8"))))
    (properties `((upstream-name . "LIM")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-diagram" ,r-diagram)
       ("r-limsolve" ,r-limsolve)))
    (home-page "https://cran.r-project.org/web/packages/LIM/")
    (synopsis "Linear inverse model examples and solution methods")
    (description
     "This package provides functions that read and solve linear inverse
problems (food web problems, linear programming problems).")
    (license license:gpl2+)))

(define-public r-shinycssloaders
  (package
    (name "r-shinycssloaders")
    (version "0.3")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "shinycssloaders" version))
       (sha256
        (base32
         "1gzq1lhcnhqd145ys3ixf0l13l560fiqr2sc3m2nrijwxlgcw54d"))))
    (properties
     `((upstream-name . "shinycssloaders")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-digest" ,r-digest)
       ("r-glue" ,r-glue)
       ("r-shiny" ,r-shiny)))
    (home-page "https://github.com/andrewsali/shinycssloaders")
    (synopsis "Add CSS loading animations to Shiny outputs")
    (description
     "This package provides tools to create a lightweight Shiny wrapper for
the css-loaders created by Luke Hass
@url{https://github.com/lukehaas/css-loaders}.  Wrapping a Shiny output will
automatically show a loader when the output is (re)calculating.")
    (license license:gpl3)))

(define-public r-rsvg
  (package
    (name "r-rsvg")
    (version "1.3")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "rsvg" version))
       (sha256
        (base32
         "11mccgf6hfskg45wqc114sx3qy2r494y6axdf73z6xwhs1wpm97g"))))
    (properties `((upstream-name . "rsvg")))
    (build-system r-build-system)
    (inputs
     `(("librsvg" ,librsvg)
       ("zlib" ,zlib)))
    (native-inputs
     `(("pkg-config" ,pkg-config)))
    (home-page "https://github.com/jeroen/rsvg#readme")
    (synopsis "Render SVG images into PDF, PNG, PostScript, or Bitmap arrays")
    (description
     "This package allows you to render vector-based SVG images into
high-quality custom-size bitmap arrays using the librsvg2 library.  The
resulting bitmap can be written to e.g. PNG, JPEG or WEBP format.  In
addition, the package can convert images directly to various formats such as
PDF or PostScript.")
    (license license:expat)))

(define-public r-influencer
  (package
    (name "r-influencer")
    (version "0.1.0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "influenceR" version))
       (sha256
        (base32
         "12p9362hkndlnz1rd8j2rykg57kbm6l7ks60by3rd25xg50k5jag"))))
    (properties `((upstream-name . "influenceR")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-igraph" ,r-igraph)
       ("r-matrix" ,r-matrix)))
    (home-page "https://github.com/rcc-uchicago/influenceR")
    (synopsis "Tools to quantify structural importance of nodes in a network")
    (description
     "This package provides functionality to compute various node centrality
measures on networks.  Included are functions to compute betweenness
centrality (by utilizing Madduri and Bader's SNAP library), implementations of
Burt's constraint and @dfn{effective network size} (ENS) metrics, Borgatti's
algorithm to identify key players, and Valente's bridging metric.  The
betweenness, Key Players, and bridging implementations are parallelized with
OpenMP.")
    (license license:gpl2)))

(define-public r-emplik
  (package
    (name "r-emplik")
    (version "1.0-4.3")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "emplik" version))
       (sha256
        (base32
         "1g4hz85bvw29c77zs0ig487z92jjl682vv457x81l077h0psvk7c"))))
    (properties `((upstream-name . "emplik")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-quantreg" ,r-quantreg)))
    (home-page "https://www.ms.uky.edu/~mai/EmpLik.html")
    (synopsis "Empirical likelihood ratio for censored/truncated data")
    (description
     "This package provides empirical likelihood ratio tests for
means/quantiles/hazards from possibly censored and/or truncated data.  It also
does regression.")
    (license license:gpl2+)))

(define-public r-imputeyn
  (package
    (name "r-imputeyn")
    (version "1.3")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "imputeYn" version))
       (sha256
        (base32
         "1b21w1aa5f7yiq8k0wa86wvbg4ij7f6ldwn6asfqwb0b90rvsgvs"))))
    (properties `((upstream-name . "imputeYn")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-boot" ,r-boot)
       ("r-emplik" ,r-emplik)
       ("r-mvtnorm" ,r-mvtnorm)
       ("r-quadprog" ,r-quadprog)
       ("r-survival" ,r-survival)))
    (home-page "https://cran.r-project.org/web/packages/imputeYn/")
    (synopsis "Impute last largest censored observation under weighted least squares")
    (description
     "This package allows for the imputation of the last largest censored
observantions.  This method brings less bias and more efficient estimates for
AFT models.")
    (license license:gpl2)))

(define-public r-adapenetclass
  (package
    (name "r-adapenetclass")
    (version "1.2")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "AdapEnetClass" version))
       (sha256
        (base32
         "01k3mj4g1ckbng7wkzzn9h0k9yf01cpnnkly0sjda574c5jhj0rc"))))
    (properties `((upstream-name . "AdapEnetClass")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-glmnet" ,r-glmnet)
       ("r-imputeyn" ,r-imputeyn)
       ("r-lars" ,r-lars)
       ("r-quadprog" ,r-quadprog)))
    (home-page "https://cran.r-project.org/web/packages/AdapEnetClass/")
    (synopsis "Class of adaptive elastic net methods for censored data")
    (description
     "This package provides methods for variable selection for AFT models.")
    (license license:gpl2)))

(define-public r-flock
  (package
    (name "r-flock")
    (version "0.7")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "flock" version))
       (sha256
        (base32
         "1zg93p74icj4bhxnmnssj2xp6vw4yaksyavq03497v33xfpdxss7"))))
    (properties `((upstream-name . "flock")))
    (build-system r-build-system)
    (propagated-inputs `(("r-rcpp" ,r-rcpp)))
    (home-page "https://cran.r-project.org/web/packages/flock/")
    (synopsis "Process synchronization using file locks")
    (description
     "This package implements synchronization between R processes (spawned by
using the @code{parallel} package for instance) using file locks.  It supports
both exclusive and shared locking.")
    (license license:asl2.0)))

(define-public r-archivist
  (package
    (name "r-archivist")
    (version "2.3.4")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "archivist" version))
       (sha256
        (base32
         "1i11hrcq1910jgd6diw6h3sxx624v57zjianm49pqvb2dvd0b8y7"))))
    (properties `((upstream-name . "archivist")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-dbi" ,r-dbi)
       ("r-digest" ,r-digest)
       ("r-flock" ,r-flock)
       ("r-httr" ,r-httr)
       ("r-lubridate" ,r-lubridate)
       ("r-magrittr" ,r-magrittr)
       ("r-rcurl" ,r-rcurl)
       ("r-rsqlite" ,r-rsqlite)))
    (home-page "https://pbiecek.github.io/archivist/")
    (synopsis "Tools for storing, restoring and searching for R objects")
    (description
     "Data exploration and modelling is a process in which a lot of data
artifacts are produced.  Artifacts like: subsets, data aggregates, plots,
statistical models, different versions of data sets and different versions of
results.  Archivist helps to store and manage artifacts created in R.  It
allows you to store selected artifacts as binary files together with their
metadata and relations.  Archivist allows sharing artifacts with others.  It
can look for already created artifacts by using its class, name, date of the
creation or other properties.  It also makes it easy to restore such
artifacts.")
    (license license:gpl2)))

(define-public r-versions
  (package
    (name "r-versions")
    (version "0.3")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "versions" version))
       (sha256
        (base32
         "0zm49j785dgv7fyr1yl9q5f0dsk8hhpim5q5bpkgrkzv7pwjribd"))))
    (properties `((upstream-name . "versions")))
    (build-system r-build-system)
    (home-page "https://cran.r-project.org/web/packages/versions/")
    (synopsis "Query and install specific versions of CRAN packages")
    (description
     "This package allows you to install specified versions of R packages
hosted on CRAN and provides functions to list available versions and the
versions of currently installed packages.")
    (license license:bsd-3)))

(define-public r-adapr
  (package
    (name "r-adapr")
    (version "2.0.0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "adapr" version))
       (sha256
        (base32
         "1s57jdbi5pik56xjz1d4438ax6cywg2yq2s47h5g6wrwvpgr1qfw"))))
    (properties `((upstream-name . "adapr")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-archivist" ,r-archivist)
       ("r-devtools" ,r-devtools)
       ("r-digest" ,r-digest)
       ("r-doparallel" ,r-doparallel)
       ("r-gdata" ,r-gdata)
       ("r-ggplot2" ,r-ggplot2)
       ("r-git2r" ,r-git2r)
       ("r-igraph" ,r-igraph)
       ("r-knitr" ,r-knitr)
       ("r-plotly" ,r-plotly)
       ("r-plyr" ,r-plyr)
       ("r-rmarkdown" ,r-rmarkdown)
       ("r-shiny" ,r-shiny)
       ("r-shinydashboard" ,r-shinydashboard)
       ("r-versions" ,r-versions)))
    (home-page "https://cran.r-project.org/web/packages/adapr/")
    (synopsis "Implementation of an accountable data analysis process")
    (description
     "This package tracks reading and writing within R scripts that are
organized into a directed acyclic graph.  It contains an interactive Shiny
application @code{adaprApp()}.  It uses Git and file hashes to track version
histories of inputs and outputs.")
    (license license:lgpl2.0)))

(define-public r-adapsamp
  (package
    (name "r-adapsamp")
    (version "1.1.1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "AdapSamp" version))
       (sha256
        (base32
         "1jayjrsiib2ij4rxxj59g71r3xhzl5yqh0lhi8k6cfy03i7dkvis"))))
    (properties `((upstream-name . "AdapSamp")))
    (build-system r-build-system)
    (propagated-inputs `(("r-pracma" ,r-pracma)))
    (home-page "https://cran.r-project.org/web/packages/AdapSamp/")
    (synopsis "Adaptive sampling algorithms")
    (description
     "For distributions whose probability density functions are log-concave,
the adaptive rejection sampling algorithm can be used to build envelope
functions for sampling.  For others, the modified adaptive rejection sampling
algorithm, the concave-convex adaptive rejection sampling algorithm, and the
adaptive slice sampling algorithm can be used.  This R package mainly includes
these four functions: @code{rARS()}, @code{rMARS()}, @code{rCCARS()}, and
@code{rASS()}.  These functions can realize sampling based on the algorithms
above.")
    (license license:gpl2)))

(define-public r-adaptalint
  (package
    (name "r-adaptalint")
    (version "0.2.4")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "adaptalint" version))
       (sha256
        (base32
         "15qdcvnnbgcps8j5k79354wsc9alswijv8lcafg2i3lghaw536yf"))))
    (properties `((upstream-name . "adaptalint")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-dplyr" ,r-dplyr)
       ("r-lintr" ,r-lintr)
       ("r-purrr" ,r-purrr)))
    (home-page "https://cran.r-project.org/web/packages/adaptalint/")
    (synopsis "Check R code style")
    (description
     "This package provides tools to infer the code style (which style rules
are followed and which ones are not) from one package and use it to check
another.  This makes it easier to find and correct the most important problems
first.")
    (license license:gpl3)))

(define-public r-fracdiff
  (package
    (name "r-fracdiff")
    (version "1.5-1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "fracdiff" version))
       (sha256
        (base32
         "1dhfjlhr9sb38qgpsx0sm73l9lgc13d0fk32l7fmjfnalhr3n45q"))))
    (properties `((upstream-name . "fracdiff")))
    (build-system r-build-system)
    (home-page "https://github.com/mmaechler/fracdiff")
    (synopsis
     "Fractionally differenced ARIMA aka ARFIMA(P,d,q) models")
    (description
     "This package provides tools for the maximum likelihood estimation of the
parameters of a fractionally differenced ARIMA(p,d,q) model (Haslett and
Raftery, Appl.Statistics, 1989); it includes inference and basic methods.")
    (license license:gpl2+)))

(define-public r-forecast
  (package
    (name "r-forecast")
    (version "8.12")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "forecast" version))
       (sha256
        (base32
         "1ycj5z4wd5a16nlcjy07dqm8jkih240xa02cn4wvysnnhkapyq7b"))))
    (properties `((upstream-name . "forecast")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-colorspace" ,r-colorspace)
       ("r-fracdiff" ,r-fracdiff)
       ("r-ggplot2" ,r-ggplot2)
       ("r-lmtest" ,r-lmtest)
       ("r-magrittr" ,r-magrittr)
       ("r-nnet" ,r-nnet)
       ("r-rcpp" ,r-rcpp)
       ("r-rcpparmadillo" ,r-rcpparmadillo)
       ("r-timedate" ,r-timedate)
       ("r-tseries" ,r-tseries)
       ("r-urca" ,r-urca)
       ("r-zoo" ,r-zoo)))
    (native-inputs
     `(("r-knitr" ,r-knitr)))           ; needed for vignettes
    (home-page "https://pkg.robjhyndman.com/forecast/")
    (synopsis "Forecasting functions for time series and linear models")
    (description
     "This package provides methods and tools for displaying and analysing
univariate time series forecasts including exponential smoothing via state
space models and automatic ARIMA modelling.")
    (license license:gpl3)))

(define-public r-xmisc
  (package
    (name "r-xmisc")
    (version "0.2.1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "Xmisc" version))
       (sha256
        (base32
         "11gwlcyxhz1p50m68cnqrxmisdk99v8vrsbvyr7k67f0kvsznzs1"))))
    (properties `((upstream-name . "Xmisc")))
    (build-system r-build-system)
    (home-page "https://cran.r-project.org/package=Xmisc")
    (synopsis
     "Xiaobei's miscellaneous classes and functions")
    (description
     "This package provides Xiaobei's miscellaneous classes and functions,
which are useful when developing R packages for @dfn{object oriented
programming} (OOP) using R Reference Class.")
    (license license:gpl2+)))

(define-public r-proxyc
  (package
    (name "r-proxyc")
    (version "0.1.5")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "proxyC" version))
       (sha256
        (base32
         "159bc42x4shm6n3rh9fc8ziv3ivq0ipmpbasrh279hhn1prc8gg6"))))
    (properties `((upstream-name . "proxyC")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-matrix" ,r-matrix)
       ("r-rcpp" ,r-rcpp)
       ("r-rcpparmadillo" ,r-rcpparmadillo)
       ("r-rcppparallel" ,r-rcppparallel)))
    (home-page "https://cran.r-project.org/package=proxyC")
    (synopsis "Compute proximity in large sparse matrices")
    (description
     "This package provides efficient tools to compute the proximity between
rows or columns of large matrices.  Functions are optimised for large sparse
matrices using the Armadillo and Intel TBB libraries.  Among several built-in
similarity/distance measures, computation of correlation, cosine similarity
and Euclidean distance is particularly fast.")
    (license license:gpl3)))

(define-public r-isocodes
  (package
    (name "r-isocodes")
    (version "2020.03.16")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "ISOcodes" version))
       (sha256
        (base32
         "1hz1sj57qkkkrgn8slsz2n4jv1fkyp40503j9rg30lxy4gmb83hn"))))
    (properties `((upstream-name . "ISOcodes")))
    (build-system r-build-system)
    (home-page "https://cran.r-project.org/package=ISOcodes")
    (synopsis "Selected ISO codes")
    (description
     "This package provides ISO language, territory, currency, script and
character codes.  It provides ISO 639 language codes, ISO 3166 territory
codes, ISO 4217 currency codes, ISO 15924 script codes, and the ISO 8859
character codes as well as the UN M.49 area codes.")
    (license license:gpl2)))

(define-public r-stopwords
  (package
    (name "r-stopwords")
    (version "1.0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "stopwords" version))
       (sha256
        (base32
         "1nmi0bpd0c238g5b8ch1v034m5ng9llhs519cgxdrj3sh9fplwlv"))))
    (properties `((upstream-name . "stopwords")))
    (build-system r-build-system)
    (propagated-inputs `(("r-isocodes" ,r-isocodes)))
    (home-page "https://github.com/quanteda/stopwords")
    (synopsis "Multilingual stopword lists")
    (description
     "This package provides multiple sources of stopwords, for use in text
analysis and natural language processing.")
    (license license:expat)))

(define-public r-spacyr
  (package
    (name "r-spacyr")
    (version "1.2.1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "spacyr" version))
       (sha256
        (base32
         "1b2ccgwsiqkvp7w37x8k7699c676q16vfrybkrfvyczyhki4s6nw"))))
    (properties `((upstream-name . "spacyr")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-data-table" ,r-data-table)
       ("r-reticulate" ,r-reticulate)))
    (home-page "https://spacyr.quanteda.io")
    (synopsis "R wrapper for the spaCy NLP library")
    (description
     "This package provides an R wrapper to the Python @dfn{natural language
processing} (NLP) library @code{spaCy}, from @url{http://spacy.io}.")
    (license license:gpl3)))

(define-public r-snowballc
  (package
    (name "r-snowballc")
    (version "0.7.0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "SnowballC" version))
       (sha256
        (base32
         "1wwm71mp4b2mjb5985x782p6xj519dfrpd40qli7lmig6afyw3xi"))))
    (properties `((upstream-name . "SnowballC")))
    (build-system r-build-system)
    (home-page "https://r-forge.r-project.org/projects/r-temis/")
    (synopsis "Snowball stemmers based on the C libstemmer UTF-8 library")
    (description
     "This package provides an R interface to the C @code{libstemmer} library
that implements Porter's word stemming algorithm for collapsing words to a
common root to aid comparison of vocabulary.  Currently supported languages
are Danish, Dutch, English, Finnish, French, German, Hungarian, Italian,
Norwegian, Portuguese, Romanian, Russian, Spanish, Swedish and Turkish.")
    (license license:bsd-3)))

(define-public r-quanteda
  (package
    (name "r-quanteda")
    (version "2.0.1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "quanteda" version))
       (sha256
        (base32
         "0pym6vdzqbkyj87m3pla229092xvvx4j830x67qflxzzdmc9dzhz"))))
    (properties `((upstream-name . "quanteda")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-data-table" ,r-data-table)
       ("r-extrafont" ,r-extrafont)
       ("r-fastmatch" ,r-fastmatch)
       ("r-ggplot2" ,r-ggplot2)
       ("r-ggrepel" ,r-ggrepel)
       ("r-jsonlite" ,r-jsonlite)
       ("r-magrittr" ,r-magrittr)
       ("r-matrix" ,r-matrix)
       ("r-network" ,r-network)
       ("r-proxyc" ,r-proxyc)
       ("r-rcpp" ,r-rcpp)
       ("r-rcpparmadillo" ,r-rcpparmadillo)
       ("r-rcppparallel" ,r-rcppparallel)
       ("r-sna" ,r-sna)
       ("r-snowballc" ,r-snowballc)
       ("r-stopwords" ,r-stopwords)
       ("r-stringi" ,r-stringi)
       ("r-xml2" ,r-xml2)
       ("r-yaml" ,r-yaml)))
    (native-inputs
     `(("r-knitr" ,r-knitr)))
    (home-page "https://quanteda.io")
    (synopsis "Quantitative analysis of textual data")
    (description
     "This package provides a fast, flexible, and comprehensive framework for
quantitative text analysis in R.  It provides functionality for corpus
management, creating and manipulating tokens and ngrams, exploring keywords in
context, forming and manipulating sparse matrices of documents by features and
feature co-occurrences, analyzing keywords, computing feature similarities and
distances, applying content dictionaries, applying supervised and unsupervised
machine learning, visually representing text and text analyses, and more.")
    (license license:gpl3)))

(define-public r-topicmodels
  (package
    (name "r-topicmodels")
    (version "0.2-9")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "topicmodels" version))
       (sha256
        (base32
         "1757r5x8bsl4dk106xg6481mvdkdz9vwg87n7rpbvdkavsvhyxs0"))))
    (properties `((upstream-name . "topicmodels")))
    (build-system r-build-system)
    (native-inputs
     `(("gsl" ,gsl)))
    (propagated-inputs
     `(("r-modeltools" ,r-modeltools)
       ("r-slam" ,r-slam)
       ("r-tm" ,r-tm)))
    (home-page "https://cran.r-project.org/package=topicmodels")
    (synopsis "Topic models")
    (description
     "This package provides an interface to the C code for @dfn{Latent
Dirichlet Allocation} (LDA) models and @dfn{Correlated Topics Models} (CTM) by
David M. Blei and co-authors and the C++ code for fitting LDA models using
Gibbs sampling by Xuan-Hieu Phan and co-authors.")
    (license license:gpl2)))

(define-public r-stm
  (package
    (name "r-stm")
    (version "1.3.5")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "stm" version))
       (sha256
        (base32
         "1yyfxaxqc6yq0yq68zhdnhpwpvsyp71dlmivn7zxixfmp932s6cn"))))
    (properties `((upstream-name . "stm")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-data-table" ,r-data-table)
       ("r-glmnet" ,r-glmnet)
       ("r-lda" ,r-lda)
       ("r-matrix" ,r-matrix)
       ("r-matrixstats" ,r-matrixstats)
       ("r-quadprog" ,r-quadprog)
       ("r-quanteda" ,r-quanteda)
       ("r-rcpp" ,r-rcpp)
       ("r-rcpparmadillo" ,r-rcpparmadillo)
       ("r-slam" ,r-slam)
       ("r-stringr" ,r-stringr)))
    (home-page "http://www.structuraltopicmodel.com/")
    (synopsis "Estimation of the Structural Topic Model")
    (description
     "The @dfn{Structural Topic Model} (STM) allows researchers to estimate
topic models with document-level covariates.  The package also includes tools
for model selection, visualization, and estimation of topic-covariate
regressions.")
    (license license:expat)))

(define-public r-polycor
  (package
    (name "r-polycor")
    (version "0.7-10")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "polycor" version))
       (sha256
        (base32
         "0wzwzklflbhi8sv9m7ijwr16v9zmkk0j0v4pbcpf32f8lbn3psna"))))
    (properties `((upstream-name . "polycor")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-matrix" ,r-matrix)
       ("r-mvtnorm" ,r-mvtnorm)))
    (home-page "https://r-forge.r-project.org/projects/polycor/")
    (synopsis "Polychoric and polyserial correlations")
    (description
     "This package provides tools to compute polychoric and polyserial
correlations by quick \"two-step\" methods or ML, optionally with standard
errors; tetrachoric and biserial correlations are special cases.")
    (license license:gpl2+)))

(define-public r-msm
  (package
    (name "r-msm")
    (version "1.6.8")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "msm" version))
       (sha256
        (base32
         "1d32y8f0vb2dfv3999liigpns788j145nrvd1xpxb9i2lsg8mwgk"))))
    (properties `((upstream-name . "msm")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-expm" ,r-expm)
       ("r-mvtnorm" ,r-mvtnorm)
       ("r-survival" ,r-survival)))
    (home-page "https://github.com/chjackson/msm")
    (synopsis "Multi-state Markov and hidden Markov models in continuous time")
    (description
     "This package provides functions for fitting continuous-time Markov and
hidden Markov multi-state models to longitudinal data.  It was designed for
processes observed at arbitrary times in continuous time (panel data) but some
other observation schemes are supported.  Both Markov transition rates and the
hidden Markov output process can be modelled in terms of covariates, which may
be constant or piecewise-constant in time.")
    (license license:gpl2+)))

(define-public r-ltm
  (package
    (name "r-ltm")
    (version "1.1-1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "ltm" version))
       (sha256
        (base32
         "1qrgzwx5l58qf5rfp1knxc84r0g943q5sdr3ky74zzwpnmrf2vf7"))))
    (properties `((upstream-name . "ltm")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-mass" ,r-mass)
       ("r-msm" ,r-msm)
       ("r-polycor" ,r-polycor)))
    (home-page "https://github.com/drizopoulos/ltm")
    (synopsis "Latent trait models under IRT")
    (description
     "This is a package supporting the analysis of multivariate dichotomous
and polytomous data using latent trait models under the Item Response Theory
approach.  It includes the Rasch, the Two-Parameter Logistic, the Birnbaum's
Three-Parameter, the Graded Response, and the Generalized Partial Credit
Models.")
    (license license:gpl2+)))

(define-public r-mi
  (package
    (name "r-mi")
    (version "1.0")
    (source
      (origin
        (method url-fetch)
        (uri (cran-uri "mi" version))
        (sha256
          (base32
            "1h47k5mpbvhid83277dvvj2di493bgzz9iarpyv3r30y219l7x1l"))))
    (properties `((upstream-name . "mi")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-arm" ,r-arm)
       ("r-matrix" ,r-matrix)))
    (home-page "http://www.stat.columbia.edu/~gelman/")
    (synopsis "Missing data imputation and model checking")
    (description
     "This package provides functions for data manipulation, imputing missing
values in an approximate Bayesian framework, diagnostics of the models used to
generate the imputations, confidence-building mechanisms to validate some of
the assumptions of the imputation algorithm, and functions to analyze multiply
imputed data sets with the appropriate degree of sampling uncertainty.")
    (license license:gpl2+)))

(define-public r-matrixcalc
  (package
    (name "r-matrixcalc")
    (version "1.0-3")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "matrixcalc" version))
       (sha256
        (base32
         "1c4w9dhi5w98qj1wwh9bbpnfk39rhiwjbanalr8bi5nmxkpcmrhp"))))
    (properties `((upstream-name . "matrixcalc")))
    (build-system r-build-system)
    (home-page "https://cran.r-project.org/web/packages/matrixcalc/")
    (synopsis "Collection of functions for matrix calculations")
    (description
     "This package provides a collection of functions to support matrix
calculations for probability, econometric and numerical analysis.  There are
additional functions that are comparable to APL functions which are useful for
actuarial models such as pension mathematics.")
    (license license:gpl2+)))

(define-public r-sem
  (package
    (name "r-sem")
    (version "3.1-9")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "sem" version))
       (sha256
        (base32
         "1f9c6g6pfx66gd2pappcsqh484ah6a0x4z47hpd46rah0817hcsa"))))
    (properties `((upstream-name . "sem")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-boot" ,r-boot)
       ("r-mass" ,r-mass)
       ("r-matrixcalc" ,r-matrixcalc)
       ("r-mi" ,r-mi)))
    (home-page "https://cran.r-project.org/package=sem")
    (synopsis "Structural equation models")
    (description
     "This package provides functions for fitting general linear structural
equation models (with observed and latent variables) using the RAM approach,
and for fitting structural equations in observed-variable models by two-stage
least squares.")
    (license license:gpl2+)))

(define-public r-semtools
  (package
    (name "r-semtools")
    (version "0.5-2")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "semTools" version))
       (sha256
        (base32
         "1zj841pszfsikzp82cmh463qyc4xhdrqjqcnhc2r8mcflv12irv6"))))
    (properties `((upstream-name . "semTools")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-lavaan" ,r-lavaan)))
    (home-page "https://github.com/simsem/semTools/wiki")
    (synopsis "Useful tools for structural equation modeling")
    (description
     "This package provides useful tools for structural equation modeling.")
    (license license:gpl2+)))

(define-public r-regsem
  (package
    (name "r-regsem")
    (version "1.5.2")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "regsem" version))
       (sha256
        (base32
         "0ch057010xfsw0nqcsarzakdbiplvxaldyqlbbacspqs65ax1yk7"))))
    (properties `((upstream-name . "regsem")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-lavaan" ,r-lavaan)
       ("r-rcpp" ,r-rcpp)
       ("r-rcpparmadillo" ,r-rcpparmadillo)
       ("r-rsolnp" ,r-rsolnp)))
    (home-page "https://cran.r-project.org/package=regsem")
    (synopsis "Regularized structural equation modeling")
    (description
     "This package uses both ridge and lasso penalties (and extensions) to
penalize specific parameters in structural equation models.  The package
offers additional cost functions, cross validation, and other extensions
beyond traditional structural equation models.  It also contains a function to
perform @dfn{exploratory mediation} (XMed).")
    (license license:gpl2+)))

(define-public r-stanheaders
  (package
    (name "r-stanheaders")
    (version "2.19.2")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "StanHeaders" version))
       (sha256
        (base32
         "0cmk0fzczx7dcywcw1dhm6gfq84qlsx77qrsk4z3bf3dhr4bznam"))))
    (properties `((upstream-name . "StanHeaders")))
    (build-system r-build-system)
    (inputs `(("pandoc" ,ghc-pandoc)))
    (native-inputs
     `(("gfortran" ,gfortran)
       ("r-knitr" ,r-knitr))) ; for vignettes
    (home-page "https://mc-stan.org/")
    (synopsis "C++ header files for Stan")
    (description
     "The C++ header files of the Stan project are provided by this package.
There is a shared object containing part of the @code{CVODES} library, but it
is not accessible from R.  @code{r-stanheaders} is only useful for developers
who want to utilize the @code{LinkingTo} directive of their package's
DESCRIPTION file to build on the Stan library without incurring unnecessary
dependencies.

The Stan project develops a probabilistic programming language that implements
full or approximate Bayesian statistical inference via Markov Chain Monte
Carlo or variational methods and implements (optionally penalized) maximum
likelihood estimation via optimization.  The Stan library includes an advanced
automatic differentiation scheme, templated statistical and linear algebra
functions that can handle the automatically differentiable scalar types (and
doubles, ints, etc.), and a parser for the Stan language.  The @code{r-rstan}
package provides user-facing R functions to parse, compile, test, estimate,
and analyze Stan models.")
    (license license:bsd-3)))

(define-public r-rpf
  (package
    (name "r-rpf")
    (version "1.0.3")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "rpf" version))
       (sha256
        (base32
         "1i2kqd7nx55nn35qnw89xmnqk23x9c8xhkh736c2xg7k2ai84ybl"))))
    (properties `((upstream-name . "rpf")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-lifecycle" ,r-lifecycle)
       ("r-mvtnorm" ,r-mvtnorm)
       ("r-rcpp" ,r-rcpp)
       ("r-rcppeigen" ,r-rcppeigen)))
    (home-page "https://github.com/jpritikin/rpf")
    (synopsis "Response probability functions")
    (description
     "The purpose of this package is to factor out logic and math common to
Item Factor Analysis fitting, diagnostics, and analysis.  It is envisioned as
core support code suitable for more specialized IRT packages to build upon.
Complete access to optimized C functions is made available with
@code{R_RegisterCCallable()}.")
    (license license:gpl3+)))

(define-public r-openmx
  (package
    (name "r-openmx")
    (version "2.17.3")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "OpenMx" version))
       (sha256
        (base32
         "1s2pcg281ag3qz2wz8yi826f2d3kj3qg916js7zz0nsrljcyv5bc"))))
    (properties `((upstream-name . "OpenMx")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-bh" ,r-bh)
       ("r-digest" ,r-digest)
       ("r-mass" ,r-mass)
       ("r-matrix" ,r-matrix)
       ("r-rcpp" ,r-rcpp)
       ("r-rcppeigen" ,r-rcppeigen)
       ("r-rpf" ,r-rpf)
       ("r-stanheaders" ,r-stanheaders)))
    (native-inputs `(("gfortran" ,gfortran)))
    (home-page "http://openmx.ssri.psu.edu")
    (synopsis "Extended structural equation modelling")
    (description
     "This package allows for the estimation of a wide variety of advanced
multivariate statistical models.  It consists of a library of functions and
optimizers that allow you to quickly and flexibly define an SEM model and
estimate parameters given observed data.")
    (license license:asl2.0)))

(define-public r-kutils
  (package
    (name "r-kutils")
    (version "1.69")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "kutils" version))
       (sha256
        (base32
         "12pg26a85h0jxlfcyai68dbh4bq1gnq8v1ngi8k9qvafbrpc6gx8"))))
    (properties `((upstream-name . "kutils")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-foreign" ,r-foreign)
       ("r-lavaan" ,r-lavaan)
       ("r-openxlsx" ,r-openxlsx)
       ("r-plyr" ,r-plyr)
       ("r-runit" ,r-runit)
       ("r-xtable" ,r-xtable)))
    (home-page "https://cran.r-project.org/package=kutils")
    (synopsis "Project management tools")
    (description
     "This package provides tools for data importation, recoding, and
inspection.  There are functions to create new project folders, R code
templates, create uniquely named output directories, and to quickly obtain a
visual summary for each variable in a data frame.  The main feature here is
the systematic implementation of the \"variable key\" framework for data
importation and recoding.")
    (license license:gpl2)))

(define-public r-rockchalk
  (package
    (name "r-rockchalk")
    (version "1.8.144")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "rockchalk" version))
       (sha256
        (base32
         "07dp1n155b9gfvk8l30h6bhjbhbylsjxfzns08mryn4mxj3nqpnb"))))
    (properties `((upstream-name . "rockchalk")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-cardata" ,r-cardata)
       ("r-kutils" ,r-kutils)
       ("r-lme4" ,r-lme4)
       ("r-mass" ,r-mass)))
    (home-page "https://cran.r-project.org/package=rockchalk")
    (synopsis "Regression estimation and presentation")
    (description
     "This package provides a collection of functions for interpretation and
presentation of regression analysis.  These functions are used to produce the
statistics lectures in @url{http://pj.freefaculty.org/guides}.  The package
includes regression diagnostics, regression tables, and plots of interactions
and \"moderator\" variables.  The emphasis is on \"mean-centered\" and
\"residual-centered\" predictors.  The vignette @code{rockchalk} offers a
fairly comprehensive overview.")
    (license license:gpl3+)))

(define-public r-lisreltor
  (package
    (name "r-lisreltor")
    (version "0.1.4")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "lisrelToR" version))
       (sha256
        (base32
         "0zicq0z3hhixan1p1apybnf3v5s6v6ysll4pcz8ivygwr2swv3p5"))))
    (properties `((upstream-name . "lisrelToR")))
    (build-system r-build-system)
    (home-page "https://cran.r-project.org/package=lisrelToR")
    (synopsis "Import output from LISREL into R")
    (description
     "This is an unofficial package aimed at automating the import of LISREL
output in R.")
    (license license:gpl2)))

(define-public r-bdgraph
  (package
    (name "r-bdgraph")
    (version "2.62")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "BDgraph" version))
       (sha256
        (base32
         "1b1vfar940swvn3pcil848qsp8ji50fjjll8jjzp6y2adx0f8pby"))))
    (properties `((upstream-name . "BDgraph")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-igraph" ,r-igraph)))
    (home-page "https://www.uva.nl/profile/a.mohammadi")
    (synopsis "Bayesian structure learning in graphical models")
    (description
     "This package provides statistical tools for Bayesian structure learning
in undirected graphical models for continuous, discrete, and mixed data.  It
uses a trans-dimensional @dfn{Markov Chain Monte Carlo} (MCMC) approach based
on a continuous-time birth-death process.")
    (license license:gpl2+)))

(define-public r-d3network
  (package
    (name "r-d3network")
    (version "0.5.2.1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "d3Network" version))
       (sha256
        (base32
         "1gh979z9wksyxxxdzlfzibn0ysvf6h1ij7vwpd55fvbwr308syaw"))))
    (properties `((upstream-name . "d3Network")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-plyr" ,r-plyr)
       ("r-rjson" ,r-rjson)
       ("r-whisker" ,r-whisker)))
    (home-page "http://christophergandrud.github.io/d3Network/")
    (synopsis "Create D3 JavaScript network, tree, dendrogram, and Sankey graphs")
    (description
     "This package is intended to make it easy to create D3 JavaScript
network, tree, dendrogram, and Sankey graphs from R using data frames.")
    (license license:gpl3+)))

(define-public r-qgraph
  (package
    (name "r-qgraph")
    (version "1.6.5")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "qgraph" version))
       (sha256
        (base32
         "0pwys9irxvp0ap158drplyypkplbmwqinv0fmlsblk7q875cr592"))))
    (properties `((upstream-name . "qgraph")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-abind" ,r-abind)
       ("r-bdgraph" ,r-bdgraph)
       ("r-colorspace" ,r-colorspace)
       ("r-corpcor" ,r-corpcor)
       ("r-d3network" ,r-d3network)
       ("r-dplyr" ,r-dplyr)
       ("r-fdrtool" ,r-fdrtool)
       ("r-ggplot2" ,r-ggplot2)
       ("r-ggraph" ,r-ggraph)
       ("r-glasso" ,r-glasso)
       ("r-gtools" ,r-gtools)
       ("r-hmisc" ,r-hmisc)
       ("r-huge" ,r-huge)
       ("r-igraph" ,r-igraph)
       ("r-jpeg" ,r-jpeg)
       ("r-lavaan" ,r-lavaan)
       ("r-matrix" ,r-matrix)
       ("r-pbapply" ,r-pbapply)
       ("r-plyr" ,r-plyr)
       ("r-png" ,r-png)
       ("r-psych" ,r-psych)
       ("r-rcpp" ,r-rcpp)
       ("r-reshape2" ,r-reshape2)
       ("r-tidygraph" ,r-tidygraph)))
    (home-page "http://sachaepskamp.com/qgraph/")
    (synopsis "Weighted network visualization and analysis")
    (description
     "This package implements tools for weighted network visualization and
analysis, as well as Gaussian graphical model computation.  It contains graph
plotting methods, and tools for psychometric data visualization and graphical
model estimation.  See Epskamp et al. (2012)
@url{doi:10.18637/jss.v048.i04}.")
    (license license:gpl2)))

(define-public r-semplot
  (package
    (name "r-semplot")
    (version "1.1.2")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "semPlot" version))
       (sha256
        (base32
         "0l1v9yi1pv59iwfknw4dh9qskk5y8r347jq1vq13gnfd3bmd71xr"))))
    (properties `((upstream-name . "semPlot")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-colorspace" ,r-colorspace)
       ("r-corpcor" ,r-corpcor)
       ("r-igraph" ,r-igraph)
       ("r-lavaan" ,r-lavaan)
       ("r-lisreltor" ,r-lisreltor)
       ("r-openmx" ,r-openmx)
       ("r-plyr" ,r-plyr)
       ("r-qgraph" ,r-qgraph)
       ("r-regsem" ,r-regsem)
       ("r-rockchalk" ,r-rockchalk)
       ("r-sem" ,r-sem)
       ("r-xml" ,r-xml)))
    (home-page "https://github.com/SachaEpskamp/semPlot")
    (synopsis "Unified visualizations of structural equation models")
    (description
     "Structural equation modeling (SEM) has a long history of representing
models graphically as path diagrams.  The semPlot package for R fills the gap
between advanced, but time-consuming, graphical software and the limited
graphics produced automatically by SEM software.  In addition, semPlot offers
more functionality than drawing path diagrams: it can act as a common ground
for importing SEM results into R.  Any result usable as input to semPlot can
also be represented in any of the three popular SEM frame-works, as well as
translated to input syntax for the R packages @code{sem} and @code{lavaan}.")
    (license license:gpl2)))

(define-public r-cdm
  (package
    (name "r-cdm")
    (version "7.5-15")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "CDM" version))
       (sha256
        (base32
         "159ny2dz0rf1r3k1mqlfwambffc8rx425sggf5bn51nybpzanq3l"))))
    (properties `((upstream-name . "CDM")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-mvtnorm" ,r-mvtnorm)
       ("r-polycor" ,r-polycor)
       ("r-rcpp" ,r-rcpp)
       ("r-rcpparmadillo" ,r-rcpparmadillo)))
    (home-page
     "https://github.com/alexanderrobitzsch/CDM")
    (synopsis "Cognitive diagnosis modeling")
    (description
     "This package provides functions for cognitive diagnosis modeling and
multidimensional item response modeling for dichotomous and polytomous item
responses.  It enables the estimation of the DINA and DINO model, the multiple
group (polytomous) GDINA model, the multiple choice DINA model, the general
diagnostic model (GDM), the structured latent class model (SLCA), and
regularized latent class analysis.  See George, Robitzsch, Kiefer, Gross, and
Uenlue (2017) @url{doi:10.18637/jss.v074.i02} for further details on
estimation and the package structure.  For tutorials on how to use the CDM
package see George and Robitzsch (2015, @url{doi:10.20982/tqmp.11.3.p189}) as
well as Ravand and Robitzsch (2015).")
    (license license:gpl2+)))

(define-public r-tam
  (package
    (name "r-tam")
    (version "3.4-26")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "TAM" version))
       (sha256
        (base32
         "111d7qkxhwh1lfvldyh9d61pdb5vb6x8lr8n9h95ssvw07vjqvk9"))))
    (properties `((upstream-name . "TAM")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-cdm" ,r-cdm)
       ("r-rcpp" ,r-rcpp)
       ("r-rcpparmadillo" ,r-rcpparmadillo)))
    (home-page "http://www.edmeasurementsurveys.com/TAM/Tutorials/")
    (synopsis "Test analysis modules")
    (description
     "This package includes tools for marginal maximum likelihood estimation
and joint maximum likelihood estimation for unidimensional and
multidimensional item response models.  The package functionality covers the
Rasch model, 2PL model, 3PL model, generalized partial credit model,
multi-faceted Rasch model, nominal item response model, structured latent
class model, mixture distribution IRT models, and located latent class models.
Latent regression models and plausible value imputation are also supported.")
    (license license:gpl2+)))

(define-public r-erm
  (package
    (name "r-erm")
    (version "1.0-1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "eRm" version))
       (sha256
        (base32
         "0njqzznnhnkvalmhiq5yq1w7gwp2myki5cv61w42ydvd27hdyyg9"))))
    (properties `((upstream-name . "eRm")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-colorspace" ,r-colorspace)
       ("r-lattice" ,r-lattice)
       ("r-mass" ,r-mass)
       ("r-matrix" ,r-matrix)
       ("r-psych" ,r-psych)))
    (native-inputs `(("gfortran" ,gfortran)))
    (home-page "https://cran.r-project.org/package=eRm")
    (synopsis "Extended Rasch modeling")
    (description
     "This package provides tools to fit @dfn{Rasch models} (RM), @dfn{linear
logistic test models} (LLTM), @dfn{rating scale model} (RSM), @dfn{linear
rating scale models} (LRSM), @dfn{partial credit models} (PCM), and
@dfn{linear partial credit models} (LPCM).  Missing values are allowed in the
data matrix.  Additional features are the ML estimation of the person
parameters, Andersen's LR-test, item-specific Wald test, Martin-Loef-Test,
nonparametric Monte-Carlo Tests, itemfit and personfit statistics including
infit and outfit measures, ICC and other plots, automated stepwise item
elimination, and a simulation module for various binary data matrices.")
    (license license:gpl3)))

(define-public r-irtoys
  (package
    (name "r-irtoys")
    (version "0.2.1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "irtoys" version))
       (sha256
        (base32
         "0h6iiaxikhbxhbyksbjnb09qdxinlkwr2v9yzs5wslbni14paq5q"))))
    (properties `((upstream-name . "irtoys")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-ltm" ,r-ltm)
       ("r-sm" ,r-sm)))
    (home-page "https://cran.r-project.org/package=irtoys")
    (synopsis "Collection of functions related to Item Response Theory (IRT)")
    (description
     "This package provides a collection of functions useful in learning and
practicing @dfn{Item Response Theory} (IRT), which can be combined into larger
programs.  It provides basic CTT analysis, a simple common interface to the
estimation of item parameters in IRT models for binary responses with three
different programs (ICL, BILOG-MG, and ltm), ability estimation (MLE, BME,
EAP, WLE, plausible values), item and person fit statistics, scaling
methods (MM, MS, Stocking-Lord, and the complete Hebaera method), and a rich
array of parametric and non-parametric (kernel) plots.  It estimates and plots
Haberman's interaction model when all items are dichotomously scored.")
    (license license:gpl2+)))

(define-public r-iheatmapr
  (package
    (name "r-iheatmapr")
    (version "0.4.12")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "iheatmapr" version))
       (sha256
        (base32
         "0s479j9l35xiss599vablxgvg6i2j9zq9sxphsq4vdk3bafg84bw"))))
    (properties `((upstream-name . "iheatmapr")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-fastcluster" ,r-fastcluster)
       ("r-ggdendro" ,r-ggdendro)
       ("r-htmlwidgets" ,r-htmlwidgets)
       ("r-jsonlite" ,r-jsonlite)
       ("r-knitr" ,r-knitr)
       ("r-magrittr" ,r-magrittr)
       ("r-plyr" ,r-plyr)
       ("r-rcolorbrewer" ,r-rcolorbrewer)
       ("r-s4vectors" ,r-s4vectors)
       ("r-scales" ,r-scales)))
    (home-page "https://docs.ropensci.org/iheatmapr")
    (synopsis "Interactive, Complex Heatmaps")
    (description
     "iheatmapr is an R package for building complex, interactive heatmaps
using modular building blocks.  \"Complex\" heatmaps are heatmaps in which
subplots along the rows or columns of the main heatmap add more information
about each row or column.  For example, a one column additional heatmap may
indicate what group a particular row or column belongs to.  Complex heatmaps
may also include multiple side by side heatmaps which show different types of
data for the same conditions.  Interactivity can improve complex heatmaps by
providing tooltips with information about each cell and enabling zooming into
interesting features. iheatmapr uses the plotly library for interactivity.")
    (license license:expat)))

(define-public r-packrat
  (package
    (name "r-packrat")
    (version "0.5.0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "packrat" version))
       (sha256
        (base32
         "1xy5dd2hrpqa07jfl4s7dsrya05mf36ms74j833scdz0zf89586n"))))
    (properties `((upstream-name . "packrat")))
    (build-system r-build-system)
    (home-page "https://github.com/rstudio/packrat/")
    (synopsis "Dependency management R projects")
    (description
     "This package provides a dependency manager for R projects that allows
you to manage the R packages your project depends on in an isolated, portable,
and reproducible way.")
    (license license:gpl2)))

(define-public r-rsconnect
  (package
    (name "r-rsconnect")
    (version "0.8.16")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "rsconnect" version))
       (sha256
        (base32
         "05ii0p0p7xpf8z0c1594s5q7wpwcs7lmlddrd67s5p2ka5m8qwiz"))))
    (properties `((upstream-name . "rsconnect")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-curl" ,r-curl)
       ("r-digest" ,r-digest)
       ("r-jsonlite" ,r-jsonlite)
       ("r-openssl" ,r-openssl)
       ("r-packrat" ,r-packrat)
       ("r-rstudioapi" ,r-rstudioapi)
       ("r-yaml" ,r-yaml)))
    (home-page "https://github.com/rstudio/rsconnect")
    (synopsis "Deployment interface for R Markdown documents and Shiny applications")
    (description
     "This package provides a programmatic deployment interface for RPubs,
shinyapps.io, and RStudio Connect.  Supported content types include R Markdown
documents, Shiny applications, Plumber APIs, plots, and static web content.")
    (license license:gpl2)))

;; This package includes minified JavaScript files.  When upgrading please
;; check that there are no new minified JavaScript files.
(define-public r-dygraphs
  (package
    (name "r-dygraphs")
    (version "1.1.1.6")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "dygraphs" version))
       (sha256
        (base32
         "022j007mzfa9k2n31yg4aizcsf571vv3jip092h23rqj03rk3ly3"))))
    (properties `((upstream-name . "dygraphs")))
    (build-system r-build-system)
    (arguments
     `(#:modules ((guix build utils)
                  (guix build r-build-system)
                  (srfi srfi-1)
                  (ice-9 popen))
       #:phases
       (modify-phases %standard-phases
         (add-after 'unpack 'process-javascript
           (lambda* (#:key inputs #:allow-other-keys)
             (with-directory-excursion "inst/htmlwidgets/lib/"
               (call-with-values
                   (lambda ()
                     (unzip2
                      `(("dygraphs/dygraph-combined-dev.js"
                         "dygraph-combined.js")
                        (,(assoc-ref inputs "js-jquery")
                         "jquery/jquery.min.js")
                        (,(assoc-ref inputs "js-fquarter")
                         "fquarter/moment-fquarter.min.js"))))
                 (lambda (sources targets)
                   (for-each (lambda (source target)
                               (format #t "Processing ~a --> ~a~%"
                                       source target)
                               (let ((minified (open-pipe* OPEN_READ "uglify-js" source)))
                                 (call-with-output-file target
                                   (lambda (port)
                                     (dump-port minified port)))))
                             sources targets))))
             #t)))))
    (native-inputs
     `(("uglify-js" ,uglify-js)
       ;; They actually use version 1.11.1, but this more recent version
       ;; should be just fine.
       ("js-jquery"
        ,(origin
           (method url-fetch)
           (uri "https://code.jquery.com/jquery-1.12.4.js")
           (sha256
            (base32
             "0x9mrc1668icvhpwzvgafm8xm11x9lfai9nwr66aw6pjnpwkc3s3"))))
       ("js-fquarter"
        ,(origin
           (method url-fetch)
           (uri (string-append "https://raw.githubusercontent.com/robgallen/"
                               "moment-fquarter/1.0.1/moment-fquarter.js"))
           (sha256
            (base32
             "01mdnsaibm9jy2f1qpbn692hpv309lhj5si9nagib4dawmrkffij"))))))
    (propagated-inputs
     `(("r-htmltools" ,r-htmltools)
       ("r-htmlwidgets" ,r-htmlwidgets)
       ("r-magrittr" ,r-magrittr)
       ("r-xts" ,r-xts)
       ("r-zoo" ,r-zoo)))
    (home-page "https://github.com/rstudio/dygraphs")
    (synopsis "Interface to Dygraphs interactive time series charting library")
    (description
     "This package provides an R interface to the dygraphs JavaScript charting
library (a copy of which is included in the package).  It provides rich
facilities for charting time-series data in R, including highly configurable
series- and axis-display and interactive features like zoom/pan and
series/point highlighting.")
    (license license:expat)))

(define-public r-shinystan
  (package
    (name "r-shinystan")
    (version "2.5.0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "shinystan" version))
       (sha256
        (base32
         "18alf5kiqw7y2l6m5nxxizwc2znsf9frxfsqhvgcad8hld9cbya5"))))
    (properties `((upstream-name . "shinystan")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-bayesplot" ,r-bayesplot)
       ("r-colourpicker" ,r-colourpicker)
       ("r-dt" ,r-dt)
       ("r-dygraphs" ,r-dygraphs)
       ("r-ggplot2" ,r-ggplot2)
       ("r-gridextra" ,r-gridextra)
       ("r-gtools" ,r-gtools)
       ("r-markdown" ,r-markdown)
       ("r-reshape2" ,r-reshape2)
       ("r-rsconnect" ,r-rsconnect)
       ("r-rstan" ,r-rstan)
       ("r-shiny" ,r-shiny)
       ("r-shinyjs" ,r-shinyjs)
       ("r-shinythemes" ,r-shinythemes)
       ("r-threejs" ,r-threejs)
       ("r-xtable" ,r-xtable)
       ("r-xts" ,r-xts)))
    (home-page "https://mc-stan.org/")
    (synopsis "Interactive visual and numerical analysis for Bayesian models")
    (description
     "This package provides a graphical user interface for interactive
@dfn{Markov chain Monte Carlo} (MCMC) diagnostics and plots and tables helpful
for analyzing a posterior sample.  The interface is powered by the Shiny web
application framework and works with the output of MCMC programs written in
any programming language (and has extended functionality for Stan models fit
using the @code{rstan} and @code{rstanarm} packages).")
    (license license:gpl3+)))

(define-public r-rstantools
  (package
    (name "r-rstantools")
    (version "2.0.0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "rstantools" version))
       (sha256
        (base32
         "1il0pn4ksbdkska5fmhvgaicvwnnc6cs08g6ags9fj1xkjiqmrsa"))))
    (properties `((upstream-name . "rstantools")))
    (build-system r-build-system)
    (inputs `(("pandoc" ,ghc-pandoc)))
    (propagated-inputs
     `(("r-desc" ,r-desc)
       ("r-rcpp" ,r-rcpp)))
    (home-page "https://mc-stan.org/rstantools/")
    (synopsis "Tools for developing R packages interfacing with Stan")
    (description
     "This package provides various tools for developers of R packages
interfacing with @url{https://mc-stan.org, Stan}, including functions to set
up the required package structure, S3 generics and default methods to unify
function naming across Stan-based R packages, and vignettes with
recommendations for developers.")
    (license license:gpl3+)))

(define-public r-loo
  (package
    (name "r-loo")
    (version "2.2.0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "loo" version))
       (sha256
        (base32
         "1hq1zcj76x55z9kic6cwf7mfq9pzqfbr341jbc9wp7x8ac4zcva6"))))
    (properties `((upstream-name . "loo")))
    (build-system r-build-system)
    (inputs
     `(("pandoc" ,ghc-pandoc)
       ("pandoc-citeproc" ,ghc-pandoc-citeproc)))
    (propagated-inputs
     `(("r-checkmate" ,r-checkmate)
       ("r-matrixstats" ,r-matrixstats)))
    (home-page "https://mc-stan.org/loo/")
    (synopsis "Leave-One-Out cross-validation and WAIC for Bayesian models")
    (description
     "This package provides an implementation of efficient approximate
@dfn{leave-one-out} (LOO) cross-validation for Bayesian models fit using
Markov chain Monte Carlo, as described in @url{doi:10.1007/s11222-016-9696-4}.
The approximation uses @dfn{Pareto smoothed importance sampling} (PSIS), a new
procedure for regularizing importance weights.  As a byproduct of the
calculations, we also obtain approximate standard errors for estimated
predictive errors and for the comparison of predictive errors between models.
The package also provides methods for using stacking and other model weighting
techniques to average Bayesian predictive distributions.")
    (license license:gpl3+)))

(define-public r-rstan
  (package
    (name "r-rstan")
    (version "2.19.3")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "rstan" version))
       (sha256
        (base32
         "128ndwjrhf8b1qvvqz4bl13qlm8718z9qs5ryc6gsdr3vk65s0np"))))
    (properties `((upstream-name . "rstan")))
    (build-system r-build-system)
    (arguments
     `(#:phases
       (modify-phases %standard-phases
         (add-before 'install 'set-timezone
           ;; This package is picky about timezones.
           (lambda* (#:key inputs #:allow-other-keys)
             (setenv "TZ" "UTC+1")
             (setenv "TZDIR"
                     (string-append (assoc-ref inputs "tzdata")
                                    "/share/zoneinfo"))
             #t)))))
    (native-inputs
     `(("tzdata" ,tzdata)
       ("pandoc" ,ghc-pandoc)))
    (propagated-inputs
     `(("r-bh" ,r-bh)
       ("r-ggplot2" ,r-ggplot2)
       ("r-gridextra" ,r-gridextra)
       ("r-inline" ,r-inline)
       ("r-loo" ,r-loo)
       ("r-pkgbuild" ,r-pkgbuild)
       ("r-rcpp" ,r-rcpp)
       ("r-rcppeigen" ,r-rcppeigen)
       ("r-stanheaders" ,r-stanheaders)))
    (home-page "https://discourse.mc-stan.org/")
    (synopsis "R interface to Stan")
    (description
     "User-facing R functions are provided to parse, compile, test, estimate,
and analyze Stan models by accessing the header-only Stan library provided by
the StanHeaders package.  The Stan project develops a probabilistic
programming language that implements full Bayesian statistical inference via
Markov Chain Monte Carlo, rough Bayesian inference via 'variational'
approximation, and (optionally penalized) maximum likelihood estimation via
optimization.  In all three cases, automatic differentiation is used to
quickly and accurately evaluate gradients without burdening the user with the
need to derive the partial derivatives.")
    (license license:gpl3+)))

(define-public r-rstanarm
  (package
    (name "r-rstanarm")
    (version "2.19.3")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "rstanarm" version))
       (sha256
        (base32
         "0gxjq8bdlvdd8kn3dhp12xlymdab036r7n12lzmd3xlkl4cnxq3s"))))
    (properties `((upstream-name . "rstanarm")))
    (build-system r-build-system)
    (inputs
     `(("pandoc" ,ghc-pandoc)
       ("pandoc-citeproc" ,ghc-pandoc-citeproc)))
    (propagated-inputs
     `(("r-bayesplot" ,r-bayesplot)
       ("r-bh" ,r-bh)
       ("r-ggplot2" ,r-ggplot2)
       ("r-lme4" ,r-lme4)
       ("r-loo" ,r-loo)
       ("r-matrix" ,r-matrix)
       ("r-nlme" ,r-nlme)
       ("r-rcpp" ,r-rcpp)
       ("r-rcppeigen" ,r-rcppeigen)
       ("r-rcppparallel" ,r-rcppparallel)
       ("r-rstan" ,r-rstan)
       ("r-rstantools" ,r-rstantools)
       ("r-shinystan" ,r-shinystan)
       ("r-stanheaders" ,r-stanheaders)
       ("r-survival" ,r-survival)))
    (home-page "https://mc-stan.org/rstanarm/")
    (synopsis "Bayesian applied regression modeling via Stan")
    (description
     "This package estimates previously compiled regression models using the
@code{rstan} package, which provides the R interface to the Stan C++ library
for Bayesian estimation.  Users specify models via the customary R syntax with
a formula and @code{data.frame} plus some additional arguments for priors.")
    (license license:gpl3+)))

(define-public r-kendall
  (package
    (name "r-kendall")
    (version "2.2")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "Kendall" version))
       (sha256
        (base32
         "0z2yr3x2nvdm81w2imb61hxwcbmg14kfb2bxgh3wmkmv3wfjwkwn"))))
    (properties `((upstream-name . "Kendall")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-boot" ,r-boot)))
    (native-inputs
     `(("gfortran" ,gfortran)))
    (home-page "https://cran.r-project.org/web/packages/Kendall/")
    (synopsis "Kendall rank correlation and Mann-Kendall trend test")
    (description
     "This package computes the Kendall rank correlation and Mann-Kendall
trend test.")
    (license license:gpl2+)))

(define-public r-zyp
  (package
    (name "r-zyp")
    (version "0.10-1.1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "zyp" version))
       (sha256
        (base32
         "03cxpkfbhrx1fy8l0dl9a13ghz93cqq6877wa8rig09ksdiivaw9"))))
    (properties `((upstream-name . "zyp")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-kendall" ,r-kendall)))
    (home-page "https://cran.r-project.org/web/packages/zyp/")
    (synopsis "Zhang + Yue-Pilon Trends Package")
    (description
     "This package contains an efficient implementation of Sen's slope
method (Sen, 1968) plus implementation of Xuebin Zhang's (Zhang, 1999) and
Yue-Pilon's (Yue, 2002) pre-whitening approaches to determining trends in
climate data.")
    (license license:lgpl2.1)))

(define-public r-zvcv
  (package
    (name "r-zvcv")
    (version "1.0.0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "ZVCV" version))
       (sha256
        (base32
         "1npw836q2skx54843lgxvb0rfwafckjc8k8dljykm60ad3z7zak8"))))
    (properties `((upstream-name . "ZVCV")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-abind" ,r-abind)
       ("r-glmnet" ,r-glmnet)
       ("r-mvtnorm" ,r-mvtnorm)
       ("r-partitions" ,r-partitions)
       ("r-rcpp" ,r-rcpp)
       ("r-rcpparmadillo" ,r-rcpparmadillo)))
    (home-page "https://cran.r-project.org/web/packages/ZVCV/")
    (synopsis "Zero-Variance Control Variates")
    (description
     "@dfn{Zero-variance control variates} (ZV-CV) is a post-processing method
to reduce the variance of Monte Carlo estimators of expectations using the
derivatives of the log target.  Once the derivatives are available, the only
additional computational effort is in solving a linear regression problem.
This method has been extended to higher dimensions using regularisation.  This
package can be used to easily perform ZV-CV or regularised ZV-CV when a set of
samples, derivatives and function evaluations are available.  Additional
functions for applying ZV-CV to two estimators for the normalising constant of
the posterior distribution in Bayesian statistics are also supplied.")
    (license license:gpl2+)))

(define-public r-ztype
  (package
    (name "r-ztype")
    (version "0.1.0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "ztype" version))
       (sha256
        (base32
         "0brbq2rgkl4mhjbb70kkfv47lzs66k9ppfs2klavcbripirxn5fx"))))
    (properties `((upstream-name . "ztype")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-assertthat" ,r-assertthat)
       ("r-dplyr" ,r-dplyr)
       ("r-ggplot2" ,r-ggplot2)
       ("r-lubridate" ,r-lubridate)
       ("r-magrittr" ,r-magrittr)
       ("r-rvest" ,r-rvest)
       ("r-stringr" ,r-stringr)))
    (home-page "https://cran.r-project.org/web/packages/ztype/")
    (synopsis "Run a Ztype game loaded with R functions")
    (description
     "How fast can you type R functions on your keyboard?  Find out by running
a @code{zty.pe} game: export R functions as instructions to type to destroy
opponents' vessels.")
    (license license:gpl3)))

(define-public r-zseq
  (package
    (name "r-zseq")
    (version "0.2.0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "Zseq" version))
       (sha256
        (base32
         "06dndi2b1q79bmxax11bv0l5ifcz1mhpvbn90y6a6xymrgcq0ivi"))))
    (properties `((upstream-name . "Zseq")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-gmp" ,r-gmp)))
    (home-page "https://cran.r-project.org/web/packages/Zseq/")
    (synopsis "Integer sequence generator")
    (description
     "This package generates well-known integer sequences.  The @code{gmp}
package is adopted for computing with arbitrarily large numbers.  Every
function has a hyperlink to its corresponding item in the @dfn{On-Line
Encyclopedia of Integer Sequences} (OEIS) in the function help page.")
    (license license:gpl3+)))

(define-public r-isoband
  (package
    (name "r-isoband")
    (version "0.2.0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "isoband" version))
       (sha256
        (base32
         "1r023s73qypnvpx18znr9ymylr022m90v65mz2jasn0a1kjrfcbq"))))
    (properties `((upstream-name . "isoband")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-rcpp" ,r-rcpp)
       ("r-testthat" ,r-testthat)))
    (home-page "https://github.com/wilkelab/isoband")
    (synopsis "Generate isolines and isobands from regularly spaced elevation grids")
    (description
     "This package provides a fast C++ implementation to generate contour
lines (isolines) and contour polygons (isobands) from regularly spaced grids
containing elevation data.")
    (license license:expat)))

(define-public r-ppcor
  (package
    (name "r-ppcor")
    (version "1.1")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "ppcor" version))
       (sha256
        (base32
         "1x9b2kb8s0bp92b17gby0jwzzr3i4cf3ap9c4nq7m8fav72g0y3a"))))
    (properties `((upstream-name . "ppcor")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-mass" ,r-mass)))
    (home-page "https://cran.r-project.org/web/packages/ppcor/")
    (synopsis "Partial and semi-partial correlation")
    (description
     "This package provides users not only with a function to readily
calculate the higher-order partial and semi-partial correlations but also with
statistics and p-values of the correlation coefficients.")
    (license license:gpl2)))

(define-public r-hrbrthemes
  (package
    (name "r-hrbrthemes")
    (version "0.8.0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "hrbrthemes" version))
       (sha256
        (base32 "057h60b5p53dcyjyfwlgjc1ry968s9s64dw78p443w8717zk7zpc"))))
    (properties `((upstream-name . "hrbrthemes")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-extrafont" ,r-extrafont)
       ("r-gdtools" ,r-gdtools)
       ("r-ggplot2" ,r-ggplot2)
       ("r-htmltools" ,r-htmltools)
       ("r-knitr" ,r-knitr)
       ("r-magrittr" ,r-magrittr)
       ("r-rmarkdown" ,r-rmarkdown)
       ("r-scales" ,r-scales)))
    (native-inputs
     `(("r-knitr" ,r-knitr)))
    (home-page "https://github.com/hrbrmstr/hrbrthemes/")
    (synopsis "Additional themes, theme components and utilities for @code{ggplot2}")
    (description
     "This package provides a compilation of extra @code{ggplot2} themes,
scales and utilities, including a spell check function for plot label fields
and an overall emphasis on typography.")
    (license license:expat)))

(define-public r-crochet
  (package
    (name "r-crochet")
    (version "2.2.0")
    (source
     (origin
      (method url-fetch)
      (uri (cran-uri "crochet" version))
      (sha256
       (base32
        "1cbv79nyycxk6f8ldcsnn2pvgxqlnrj0qs19nhafnq2clxy863k6"))))
    (build-system r-build-system)
    (home-page "https://github.com/agrueneberg/crochet")
    (synopsis "Implementation Helper for Matrix-Like Types")
    (description
     "Functions to help implement the extraction / subsetting / indexing
function @code{[} and replacement function @code{[<-} of custom matrix-like
types (based on S3, S4, etc.), modeled as closely to the base matrix class
as possible (with tests to prove it).")
    (license license:expat)))

(define-public r-boa
  (package
    (name "r-boa")
    (version "1.1.8-2")
    (source
     (origin
      (method url-fetch)
      (uri (cran-uri "boa" version))
      (sha256
       (base32
        "04lhqk5qfvaz1jk90glr2yi5vq7cdy0w8m6g2lnzk359l9y41zhp"))))
    (properties `((upstream-name . "boa")))
    (build-system r-build-system)
    (home-page "http://www.jstatsoft.org/v21/i11")
    (synopsis "Library for @dfn{Bayesian Output Analysis Program} (BOA) for MCMC")
    (description
     "This package provides a menu-driven program and library of functions for
carrying out convergence diagnostics and statistical and graphical analysis of
@dfn{Markov chain Monte Carlo} (MCMC) sampling output.")
    (license license:gpl2+)))

(define-public r-httpcode
  (package
    (name "r-httpcode")
    (version "0.2.0")
    (source (origin
              (method url-fetch)
              (uri (cran-uri "httpcode" version))
              (sha256
               (base32
                "06k853ihwzkcx4z3jzazpb03p91frqkwz18jy4fwr8j2nwyqbhgv"))))
    (build-system r-build-system)
    (home-page "https://github.com/sckott/httpcode")
    (synopsis "HTTP status code helper")
    (description "@code{httpcode} provides functionality for finding and
explaining the meaning of @code{HTTP} status codes.  Functions are included for
searching for codes by full or partial number, by message, and to get
appropriate dog and cat images for many status codes.")
    (license license:expat)))

(define-public r-latex2exp
  (package
    (name "r-latex2exp")
    (version "0.4.0")
    (source (origin
              (method url-fetch)
              (uri (cran-uri "latex2exp" version))
              (sha256
               (base32
                "12nbcgfmv13k6sc6m326ras9bcvy380b7rxcxphn06r3cfkby0zw"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-stringr" ,r-stringr)
       ("r-magrittr", r-magrittr)))
    (home-page "https://github.com/stefano-meschiari/latex2exp/")
    (synopsis "Use LaTeX expressions in plots")
    (description "@code{latex2exp} parses and converts LaTeX math formulas to
R's plotmath expressions, used to enter mathematical formulas and symbols to be
rendered as text, axis labels, etc. throughout R's plotting system.")
    (license license:expat)))

(define-public r-oai
  (package
    (name "r-oai")
    (version "0.3.0")
    (source (origin
              (method url-fetch)
              (uri (cran-uri "oai" version))
              (sha256
               (base32
                "1ipw9bq3ra66d1ddj1rylyyd20mlcb2i7phzhywra53s1fdifq1g"))))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-xml2" ,r-xml2)
       ("r-httr" ,r-httr)
       ("r-plyr" ,r-plyr)
       ("r-stringr" ,r-stringr)
       ("r-tibble" ,r-tibble)))
    (home-page "https://github.com/ropensci/oai/")
    (synopsis "General purpose OAI-PMH services client")
    (description "@code{oai} provides a general purpose client to work with
any @dfn{Open Archives Initiative Protocol for 'Metadata' Harvesting} (OAI-PMH)
service.  Functions are provided to work with the OAI-PMH verbs:
@code{GetRecord}, @code{Identify}, @code{ListIdentifiers},
@code{ListMetadataFormats}, @code{ListRecords}, and @code{ListSets}.")
    (license license:expat)))

(define-public r-argon2
  (package
    (name "r-argon2")
    (version "0.2-0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "argon2" version))
       (sha256
        (base32
         "0kqn06rpb39jlzizjlnc5c44mfic8llrshxn7ljgmyj35lbqwxqh"))))
    (properties `((upstream-name . "argon2")))
    (build-system r-build-system)
    (home-page "https://github.com/wrathematics/argon2")
    (synopsis "Secure password hashing based on the argon2 algorithm")
    (description
     "This package provides utilities for secure password hashing via the
argon2 algorithm.")
    (license license:bsd-2)))

(define-public r-getpass
  (package
    (name "r-getpass")
    (version "0.2-2")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "getPass" version))
       (sha256
        (base32
         "03ydafhh0sk3rcnpr3paajyji64x2ddp6p814p9mvbmyrblcgzcc"))))
    (properties `((upstream-name . "getPass")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-rstudioapi" ,r-rstudioapi)))
    (home-page "https://github.com/wrathematics/getPass")
    (synopsis "Masked user input")
    (description
     "This package provides a micro-package for reading \"passwords\", i.e.
reading user input with masking, so that the input is not displayed as it is
typed.  Currently, RStudio, the command line (every OS), and any platform
where tcltk is present are supported.")
    (license license:bsd-2)))

(define-public r-remoter
  (package
    (name "r-remoter")
    (version "0.4-0")
    (source
     (origin
       (method url-fetch)
       (uri (cran-uri "remoter" version))
       (sha256
        (base32
         "1a7m63l8phv5jnazvdqdrqkaqjwqzaac5y4jm2jn0ypy4n8jvkfl"))))
    (properties `((upstream-name . "remoter")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-argon2" ,r-argon2)
       ("r-getpass" ,r-getpass)
       ("r-pbdzmq" ,r-pbdzmq)
       ("r-png" ,r-png)))
    (home-page "https://github.com/RBigData/remoter")
    (synopsis "Control a remote R session from a local one")
    (description
     "This package provides a set of utilities for client/server computing
with R, controlling a remote R session (the server) from a local one (the
client).")
    (license license:bsd-2)))

(define-public r-asd
  (package
    (name "r-asd")
    (version "2.2")
    (source
      (origin
        (method url-fetch)
        (uri (cran-uri "asd" version))
        (sha256
          (base32
            "0p3r4qjam3sl3rpcilb0pgx4xx3ly71xqnvkv31vzjs885lgxz4l"))))
    (properties `((upstream-name . "asd")))
    (build-system r-build-system)
    (propagated-inputs
     `(("r-mvtnorm" ,r-mvtnorm)))
    (home-page "https://cran.r-project.org/web/packages/asd")
    (synopsis "Simulations for Adaptive Seamless Designs")
    (description
     "This package provdes means to run simulations for adaptive seamless
designs with and without early outcomes for treatment selection and
subpopulation type designs.")
    (license license:gpl3)))