diff options
Diffstat (limited to 'gnu/packages/bioinformatics.scm')
| -rw-r--r-- | gnu/packages/bioinformatics.scm | 195 |
1 files changed, 192 insertions, 3 deletions
diff --git a/gnu/packages/bioinformatics.scm b/gnu/packages/bioinformatics.scm index 87cf164c1a..c5157046ab 100644 --- a/gnu/packages/bioinformatics.scm +++ b/gnu/packages/bioinformatics.scm @@ -311,6 +311,7 @@ BAM files.") (sha256 (base32 "0093hkkvxmbwfaa7905s6185jymynvg42kq6sxv7fili11l5mxwz")) + (patches (search-patches "bcftools-regidx-unsigned-char.patch")) (modules '((guix build utils))) (snippet ;; Delete bundled htslib. @@ -2114,7 +2115,7 @@ identify enrichments with functional annotations of the genome.") (define-public diamond (package (name "diamond") - (version "0.9.9") + (version "0.9.10") (source (origin (method url-fetch) (uri (string-append @@ -2123,7 +2124,7 @@ identify enrichments with functional annotations of the genome.") (file-name (string-append name "-" version ".tar.gz")) (sha256 (base32 - "04i03046g3l2vk9722z47r1p7j415g97vvz6d76ywmbawyiihcb1")))) + "13qqzwg54n5dqh8pm5n3v8x6gqbczzakphwwjix63qv60hcd5bqd")))) (build-system cmake-build-system) (arguments '(#:tests? #f ; no "check" target @@ -8315,6 +8316,30 @@ package, and for letting R applications work on datasets that are larger than the available RAM.") (license license:artistic2.0))) +(define-public r-annotationfilter + (package + (name "r-annotationfilter") + (version "1.0.0") + (source (origin + (method url-fetch) + (uri (bioconductor-uri "AnnotationFilter" version)) + (sha256 + (base32 + "0pxvswjzwibdfmrkdragxmzcl844z73pmkn82z92wahwa6gjfyi7")))) + (properties + `((upstream-name . "AnnotationFilter"))) + (build-system r-build-system) + (propagated-inputs + `(("r-genomicranges" ,r-genomicranges) + ("r-lazyeval" ,r-lazyeval))) + (home-page "https://github.com/Bioconductor/AnnotationFilter") + (synopsis "Facilities for filtering Bioconductor annotation resources") + (description + "This package provides classes and other infrastructure to implement +filters for manipulating Bioconductor annotation resources. The filters are +used by @code{ensembldb}, @code{Organism.dplyr}, and other packages.") + (license license:artistic2.0))) + (define-public emboss (package (name "emboss") @@ -8672,6 +8697,52 @@ CopywriteR constitutes a widely applicable alternative to available copy number detection tools.") (license license:gpl2))) +(define-public r-methylkit + (package + (name "r-methylkit") + (version "1.2.0") + (source (origin + (method url-fetch) + (uri (bioconductor-uri "methylKit" version)) + (sha256 + (base32 + "02acdjf6jl0c1glymin84pdna4farn4vv0gb6107d9iqz3y3gkmm")))) + (properties `((upstream-name . "methylKit"))) + (build-system r-build-system) + (propagated-inputs + `(("r-data-table" ,r-data-table) + ("r-emdbook" ,r-emdbook) + ("r-fastseg" ,r-fastseg) + ("r-genomeinfodb" ,r-genomeinfodb) + ("r-genomicranges" ,r-genomicranges) + ("r-gtools" ,r-gtools) + ("r-iranges" ,r-iranges) + ("r-kernsmooth" ,r-kernsmooth) + ("r-limma" ,r-limma) + ("r-mclust" ,r-mclust) + ("r-qvalue" ,r-qvalue) + ("r-r-utils" ,r-r-utils) + ("r-rcpp" ,r-rcpp) + ("r-rhtslib" ,r-rhtslib) + ("r-rsamtools" ,r-rsamtools) + ("r-rtracklayer" ,r-rtracklayer) + ("r-s4vectors" ,r-s4vectors) + ("r-zlibbioc" ,r-zlibbioc))) + (inputs + `(("zlib" ,zlib))) + (home-page "http://code.google.com/p/methylkit/") + (synopsis + "DNA methylation analysis from high-throughput bisulfite sequencing results") + (description + "MethylKit is an R package for DNA methylation analysis and annotation +from high-throughput bisulfite sequencing. The package is designed to deal +with sequencing data from @dfn{Reduced representation bisulfite +sequencing} (RRBS) and its variants, but also target-capture methods and whole +genome bisulfite sequencing. It also has functions to analyze base-pair +resolution 5hmC data from experimental protocols such as oxBS-Seq and +TAB-Seq.") + (license license:artistic2.0))) + (define-public r-sva (package (name "r-sva") @@ -8816,7 +8887,8 @@ proteomics packages.") (properties `((upstream-name . "mzR"))) (build-system r-build-system) (inputs - `(("netcdf" ,netcdf))) + `(("boost" ,boost) + ("netcdf" ,netcdf))) (propagated-inputs `(("r-biobase" ,r-biobase) ("r-biocgenerics" ,r-biocgenerics) @@ -9234,6 +9306,123 @@ distributional differences between lanes (e.g., sequencing depth): global-scaling and full-quantile normalization.") (license license:artistic2.0))) +(define-public r-interactivedisplaybase + (package + (name "r-interactivedisplaybase") + (version "1.14.0") + (source + (origin + (method url-fetch) + (uri (bioconductor-uri "interactiveDisplayBase" version)) + (sha256 + (base32 + "12f6ap4bl3h2iwwhg8i3r9a7yyd28d8i5lb3fj1vnfvjs762r7r7")))) + (properties + `((upstream-name . "interactiveDisplayBase"))) + (build-system r-build-system) + (propagated-inputs + `(("r-biocgenerics" ,r-biocgenerics) + ("r-shiny" ,r-shiny))) + (home-page "http://bioconductor.org/packages/interactiveDisplayBase") + (synopsis "Base package for web displays of Bioconductor objects") + (description + "This package contains the basic methods needed to generate interactive +Shiny-based display methods for Bioconductor objects.") + (license license:artistic2.0))) + +(define-public r-annotationhub + (package + (name "r-annotationhub") + (version "2.8.2") + (source + (origin + (method url-fetch) + (uri (bioconductor-uri "AnnotationHub" version)) + (sha256 + (base32 + "1nh5si3j1nv37jcg4260582ayjg18851np47cskrm54prnvhwd9r")))) + (properties `((upstream-name . "AnnotationHub"))) + (build-system r-build-system) + (propagated-inputs + `(("r-annotationdbi" ,r-annotationdbi) + ("r-biocgenerics" ,r-biocgenerics) + ("r-biocinstaller" ,r-biocinstaller) + ("r-httr" ,r-httr) + ("r-interactivedisplaybase" ,r-interactivedisplaybase) + ("r-rsqlite" ,r-rsqlite) + ("r-s4vectors" ,r-s4vectors) + ("r-yaml" ,r-yaml))) + (home-page "http://bioconductor.org/packages/AnnotationHub") + (synopsis "Client to access AnnotationHub resources") + (description + "This package provides a client for the Bioconductor AnnotationHub web +resource. The AnnotationHub web resource provides a central location where +genomic files (e.g. VCF, bed, wig) and other resources from standard +locations (e.g. UCSC, Ensembl) can be discovered. The resource includes +metadata about each resource, e.g., a textual description, tags, and date of +modification. The client creates and manages a local cache of files retrieved +by the user, helping with quick and reproducible access.") + (license license:artistic2.0))) + +(define-public r-fastseg + (package + (name "r-fastseg") + (version "1.22.0") + (source + (origin + (method url-fetch) + (uri (bioconductor-uri "fastseg" version)) + (sha256 + (base32 + "083wiz03q9mynwchs9frlpp6c84dncri5ncibx6h82p228cpja6h")))) + (build-system r-build-system) + (propagated-inputs + `(("r-biobase" ,r-biobase) + ("r-biocgenerics" ,r-biocgenerics) + ("r-genomicranges" ,r-genomicranges) + ("r-iranges" ,r-iranges) + ("r-s4vectors" ,r-s4vectors))) + (home-page "http://www.bioinf.jku.at/software/fastseg/index.html") + (synopsis "Fast segmentation algorithm for genetic sequencing data") + (description + "Fastseg implements a very fast and efficient segmentation algorithm. +It can segment data from DNA microarrays and data from next generation +sequencing for example to detect copy number segments. Further it can segment +data from RNA microarrays like tiling arrays to identify transcripts. Most +generally, it can segment data given as a matrix or as a vector. Various data +formats can be used as input to fastseg like expression set objects for +microarrays or GRanges for sequencing data.") + (license license:lgpl2.0+))) + +(define-public r-qvalue + (package + (name "r-qvalue") + (version "2.8.0") + (source + (origin + (method url-fetch) + (uri (bioconductor-uri "qvalue" version)) + (sha256 + (base32 + "1dxdwa767a9r8n61r272ypi09qblcdfpzzwkmri74y5mbp1r3y4i")))) + (build-system r-build-system) + (propagated-inputs + `(("r-ggplot2" ,r-ggplot2) + ("r-reshape2" ,r-reshape2))) + (home-page "http://github.com/jdstorey/qvalue") + (synopsis "Q-value estimation for false discovery rate control") + (description + "This package takes a list of p-values resulting from the simultaneous +testing of many hypotheses and estimates their q-values and local @dfn{false +discovery rate} (FDR) values. The q-value of a test measures the proportion +of false positives incurred when that particular test is called significant. +The local FDR measures the posterior probability the null hypothesis is true +given the test's p-value. Various plots are automatically generated, allowing +one to make sensible significance cut-offs. The software can be applied to +problems in genomics, brain imaging, astrophysics, and data mining.") + ;; Any version of the LGPL. + (license license:lgpl3+))) + (define htslib-for-sambamba (let ((commit "2f3c3ea7b301f9b45737a793c0b2dcf0240e5ee5")) (package |