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diff --git a/doc/guix.texi b/doc/guix.texi
index 8241cb07bf..1b1690a8e3 100644
--- a/doc/guix.texi
+++ b/doc/guix.texi
@@ -950,6 +950,16 @@ created in @file{$HOME/.guix-profile}. This symlink always points to the
current generation of the user's default profile. Thus, users can add
@file{$HOME/.guix-profile/bin} to their @code{PATH} environment
variable, and so on.
+@cindex search paths
+If you are not using the Guix System Distribution, consider adding the
+following lines to your @file{~/.bash_profile} (@pxref{Bash Startup
+Files,,, bash, The GNU Bash Reference Manual}) so that newly-spawned
+shells get all the right environment variable definitions:
+
+@example
+GUIX_PROFILE="$HOME/.guix-profile" \
+source "$HOME/.guix-profile/etc/profile"
+@end example
In a multi-user setup, user profiles are stored in a place registered as
a @dfn{garbage-collector root}, which @file{$HOME/.guix-profile} points