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| -rw-r--r-- | gnu/packages/cran.scm | 28 |
1 files changed, 28 insertions, 0 deletions
diff --git a/gnu/packages/cran.scm b/gnu/packages/cran.scm index 6efd1a66c2..00ce9ad934 100644 --- a/gnu/packages/cran.scm +++ b/gnu/packages/cran.scm @@ -17963,3 +17963,31 @@ examples.") "This package provides tools for functional linear modeling and analysis of actigraphy data.") (license license:asl2.0))) + +(define-public r-activedriver + (package + (name "r-activedriver") + (version "1.0.0") + (source + (origin + (method url-fetch) + (uri (cran-uri "ActiveDriver" version)) + (sha256 + (base32 + "10c7ga48fwvpd5mc4dqiyw4kc2l0iz5qn4hg7xk15r1qmm5rsipa")))) + (properties `((upstream-name . "ActiveDriver"))) + (build-system r-build-system) + (propagated-inputs + `(("r-mass" ,r-mass))) + (home-page "https://cran.r-project.org/web/packages/ActiveDriver/") + (synopsis "Tools for finding cancer driver proteins") + (description + "This package provides a mutation analysis tool that discovers cancer +driver genes with frequent mutations in protein signalling sites such as +post-translational modifications (phosphorylation, ubiquitination, etc). The +Poisson generalized linear regression model identifies genes where cancer +mutations in signalling sites are more frequent than expected from the +sequence of the entire gene. Integration of mutations with signalling +information helps find new driver genes and propose candidate mechanisms to +known drivers.") + (license license:gpl2+))) |